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Items: 46

1.

Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness.

Bogeas A, Morvan-Dubois G, El-Habr EA, Lejeune FX, Defrance M, Narayanan A, Kuranda K, Burel-Vandenbos F, Sayd S, Delaunay V, Dubois LG, Parrinello H, Rialle S, Fabrega S, Idbaih A, Haiech J, Bièche I, Virolle T, Goodhardt M, Chneiweiss H, Junier MP.

Acta Neuropathol. 2018 Feb;135(2):267-283. doi: 10.1007/s00401-017-1783-x. Epub 2017 Nov 17.

2.

Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells.

Fernandez-Rebollo E, Mentrup B, Ebert R, Franzen J, Abagnale G, Sieben T, Ostrowska A, Hoffmann P, Roux PF, Rath B, Goodhardt M, Lemaitre JM, Bischof O, Jakob F, Wagner W.

Sci Rep. 2017 Jul 11;7(1):5132. doi: 10.1038/s41598-017-05207-1.

3.

Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation.

Djeghloul D, Kuranda K, Kuzniak I, Barbieri D, Naguibneva I, Choisy C, Bories JC, Dosquet C, Pla M, Vanneaux V, Socié G, Porteu F, Garrick D, Goodhardt M.

Stem Cell Reports. 2016 Jun 14;6(6):970-984. doi: 10.1016/j.stemcr.2016.05.007.

4.

Absence of bone sialoprotein (BSP) alters profoundly hematopoiesis and upregulates osteopontin.

Granito RN, Bouleftour W, Sabido O, Lescale C, Thomas M, Aubin JE, Goodhardt M, Vico L, Malaval L.

J Cell Physiol. 2015 Jun;230(6):1342-51. doi: 10.1002/jcp.24877.

PMID:
25502698
5.

Hind limb unloading, a model of spaceflight conditions, leads to decreased B lymphopoiesis similar to aging.

Lescale C, Schenten V, Djeghloul D, Bennabi M, Gaignier F, Vandamme K, Strazielle C, Kuzniak I, Petite H, Dosquet C, Frippiat JP, Goodhardt M.

FASEB J. 2015 Feb;29(2):455-63. doi: 10.1096/fj.14-259770. Epub 2014 Nov 5.

PMID:
25376832
6.

Epigenetic control of NF-κB-dependent FAS gene transcription during progression of myelodysplastic syndromes.

Ettou S, Humbrecht C, Benet B, Billot K, d'Allard D, Mariot V, Goodhardt M, Kosmider O, Mayeux P, Solary E, Fontenay M.

Mol Cancer Res. 2013 Jul;11(7):724-35. doi: 10.1158/1541-7786.MCR-12-0607. Epub 2013 Apr 19.

7.

AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway.

Parcelier A, Maharzi N, Delord M, Robledo-Sarmiento M, Nelson E, Belakhdar-Mekid H, Pla M, Kuranda K, Parietti V, Goodhardt M, Legrand N, Bernstein ID, Gluckman JC, Sigaux F, Canque B.

Blood. 2011 Aug 18;118(7):1784-96. doi: 10.1182/blood-2011-01-333179. Epub 2011 Jun 28.

8.

Age-related changes in human hematopoietic stem/progenitor cells.

Kuranda K, Vargaftig J, de la Rochere P, Dosquet C, Charron D, Bardin F, Tonnelle C, Bonnet D, Goodhardt M.

Aging Cell. 2011 Jun;10(3):542-6. doi: 10.1111/j.1474-9726.2011.00675.x. Epub 2011 Mar 22.

9.

Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age.

Lescale C, Dias S, Maës J, Cumano A, Szabo P, Charron D, Weksler ME, Dosquet C, Vieira P, Goodhardt M.

Aging Cell. 2010 Jun;9(3):410-9. doi: 10.1111/j.1474-9726.2010.00566.x. Epub 2010 Mar 13.

10.

Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells.

Brugat T, Gault N, Baccelli I, Maës J, Roborel de Climens A, Nguyen-Khac F, Davi F, Merle-Béral H, Gilson E, Goodhardt M, Delic J.

Leukemia. 2010 Jan;24(1):246-51. doi: 10.1038/leu.2009.213. Epub 2009 Oct 22. No abstract available.

PMID:
19847201
11.

Chromatin modifications in hematopoietic multipotent and committed progenitors are independent of gene subnuclear positioning relative to repressive compartments.

Guillemin C, Maleszewska M, Guais A, Maës J, Rouyez MC, Yacia A, Fichelson S, Goodhardt M, Francastel C.

Stem Cells. 2009 Jan;27(1):108-15. doi: 10.1634/stemcells.2008-0755.

12.

Lymphoid-affiliated genes are associated with active histone modifications in human hematopoietic stem cells.

Maës J, Maleszewska M, Guillemin C, Pflumio F, Six E, André-Schmutz I, Cavazzana-Calvo M, Charron D, Francastel C, Goodhardt M.

Blood. 2008 Oct 1;112(7):2722-9. doi: 10.1182/blood-2008-02-140806. Epub 2008 Jul 14.

PMID:
18625888
13.

Re-expression of DNA methylation-silenced CD44 gene in a resistant NB4 cell line: rescue of CD44-dependent cell death by cAMP.

Abecassis I, Maes J, Carrier JL, Hillion J, Goodhardt M, Medjber K, Wany L, Lanotte M, Karniguian A.

Leukemia. 2008 Mar;22(3):511-20. Epub 2007 Dec 20.

PMID:
18094716
14.

Activation of V(D)J recombination at the IgH chain JH locus occurs within a 6-kilobase chromatin domain and is associated with nucleosomal remodeling.

Maës J, Chappaz S, Cavelier P, O'Neill L, Turner B, Rougeon F, Goodhardt M.

J Immunol. 2006 May 1;176(9):5409-17.

15.
16.

The effect of age on B cell development and humoral immunity.

Weksler ME, Goodhardt M, Szabo P.

Springer Semin Immunopathol. 2002;24(1):35-52. Review. No abstract available.

PMID:
11974580
17.

Chromatin remodeling at the Ig loci prior to V(D)J recombination.

Maës J, O'Neill LP, Cavelier P, Turner BM, Rougeon F, Goodhardt M.

J Immunol. 2001 Jul 15;167(2):866-74.

18.
20.

A DNA double-strand break defective fibroblast cell line (180BR) derived from a radiosensitive patient represents a new mutant phenotype.

Badie C, Goodhardt M, Waugh A, Doyen N, Foray N, Calsou P, Singleton B, Gell D, Salles B, Jeggo P, Arlett CF, Malaise EP.

Cancer Res. 1997 Oct 15;57(20):4600-7.

21.

B lineage-restricted rearrangement of a human Ig kappa transgene.

Cavelier P, Nato F, Coquilleau I, Rolink A, Rougeon F, Goodhardt M.

Eur J Immunol. 1997 Jul;27(7):1626-31.

PMID:
9247570
22.

In vivo replication of the hamster polyomavirus genome and generation of specific deletions in the process of lymphomagenesis.

Mazur S, Goodhardt M, Feunteun J, de La Roche Saint André C.

J Virol. 1994 Sep;68(9):5629-37.

23.

The intronic immunoglobulin kappa gene enhancer acts independently on rearrangement and on transcription.

Kallenbach S, Babinet C, Pournin S, Cavelier P, Goodhardt M, Rougeon F.

Eur J Immunol. 1993 Aug;23(8):1917-21.

PMID:
8344354
24.

Methylation status of immunoglobulin kappa gene segments correlates with their recombination potential.

Goodhardt M, Cavelier P, Doyen N, Kallenbach S, Babinet C, Rougeon F.

Eur J Immunol. 1993 Aug;23(8):1789-95.

PMID:
8344341
25.

Mutation of immunoglobulin J chi splice sites does not affect the rearrangement frequency of J chi segments.

Kallenbach S, Goodhardt M, Babinet C, Rougeon F.

Res Immunol. 1991 Nov-Dec;142(9):741-7.

PMID:
1796208
26.

Biased VH gene expression in murine CD5 B cells results from age-dependent cellular selection.

Andrade L, Huetz F, Poncet P, Thomas-Vaslin V, Goodhardt M, Coutinho A.

Eur J Immunol. 1991 Sep;21(9):2017-23.

PMID:
1716209
27.

A rapid test for V(D)J recombinase activity.

Kallenbach S, Goodhardt M, Rougeon F.

Nucleic Acids Res. 1990 Nov 25;18(22):6730. No abstract available.

28.

Immunoglobulin kappa light chain gene promoter and enhancer are not responsible for B-cell restricted gene rearrangement.

Goodhardt M, Babinet C, Lutfalla G, Kallenbach S, Cavelier P, Rougeon F.

Nucleic Acids Res. 1989 Sep 25;17(18):7403-15.

29.

Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.

Goodhardt M, Cavelier P, Akimenko MA, Lutfalla G, Babinet C, Rougeon F.

Proc Natl Acad Sci U S A. 1987 Jun;84(12):4229-33.

30.

Does the guanine nucleotide regulatory protein Ni mediate progesterone inhibition of Xenopus oocyte adenylate cyclase?

Goodhardt M, Ferry N, Buscaglia M, Baulieu EE, Hanoune J.

EMBO J. 1984 Nov;3(11):2653-7.

31.

The hepatic alpha 1-adrenergic receptor.

Goodhardt M, Ferry N, Aggerbeck M, Hanoune J.

Biochem Pharmacol. 1984 Mar 15;33(6):863-8.

PMID:
6324802
32.

Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Bowen DM, Allen SJ, Benton JS, Goodhardt MJ, Haan EA, Palmer AM, Sims NR, Smith CC, Spillane JA, Esiri MM, Neary D, Snowdon JS, Wilcock GK, Davison AN.

J Neurochem. 1983 Jul;41(1):266-72.

PMID:
6306169
33.

Biochemical evidence of selective nerve cell changes in the normal ageing human and rat brain.

Allen SJ, Benton JS, Goodhardt MJ, Haan EA, Sims NR, Smith CC, Spillane JA, Bowen DM, Davison AN.

J Neurochem. 1983 Jul;41(1):256-65.

PMID:
6134787
34.

Binding of yohimbine stereoisomers to alpha-adrenoceptors in rat liver and human platelets.

Ferry N, Goodhardt M, Hanoune J, Sevenet T.

Br J Pharmacol. 1983 Feb;78(2):359-64.

35.

Hepatic alpha 1-adrenergic receptors show agonist-specific regulation by guanine nucleotides. Loss of nucleotide effect after adrenalectomy.

Goodhardt M, Ferry N, Geynet P, Hanoune J.

J Biol Chem. 1982 Oct 10;257(19):11577-83. No abstract available.

36.

Subunit structure of rat liver alpha 1 adrenergic receptor.

Guellaen G, Goodhardt M, Barouki R, Hanoune J.

Biochem Pharmacol. 1982 Sep 1;31(17):2817-20. No abstract available.

PMID:
6291546
37.

Recent advances in the purification of the alpha 1-adrenoceptor.

Guellaen G, Goodhardt M, Hanoune J.

J Cardiovasc Pharmacol. 1982;4 Suppl 1:S30-4.

PMID:
6175841
38.

Specific antibodies against the irreversible alpha-adrenergic antagonist, phenoxybenzamine.

Goodhardt M, Guellaen G, Hanoune J.

Biochem Pharmacol. 1981 Jun 15;30(12):1685-92. No abstract available.

PMID:
6115649
39.

The hepatic alpha-adrenergic receptor.

Hanoune J, Aggerbeck M, Ferry N, Borsodi A, Geynet P, Goodhardt M, Guellaen G.

Adv Cyclic Nucleotide Res. 1981;14:507-19. No abstract available.

PMID:
6116390
40.

Accelerated ageing or selective neuronal loss as an important cause of dementia?

Bowen DM, White P, Spillane JA, Goodhardt MJ, Curzon G, Iwangoff P, Meier-Ruge W, Davison AN.

Lancet. 1979 Jan 6;1(8106):11-4.

PMID:
83462
41.

Chemical pathology of organic dementias. I. Validity of biochemical measurements on human post-mortem brain specimens.

Bowen DM, Smith CB, White P, Goodhardt MJ, Spillane JA, Flack RH, Davison AN.

Brain. 1977 Sep;100(3):397-426. No abstract available.

PMID:
22388
42.

Neocortical cholinergic neurons in elderly people.

White P, Hiley CR, Goodhardt MJ, Carrasco LH, Keet JP, Williams IE, Bowen DM.

Lancet. 1977 Mar 26;1(8013):668-71.

PMID:
66473
43.

The effects of middle-cerebral-artery occlusion on neurotransmitter metabolism in baboons.

Goodhardt MJ, Strong AJ, Bowen DM, White P, Branston NM, Symon L, Davison AN.

Biochem Soc Trans. 1977;5(1):160-3. No abstract available.

PMID:
408203
44.

A comparison of the effects of ischaemia on tissue flow, electrical activity and extracellular potassium ion concentration in cerebral cortex of baboons.

Strong AJ, Goodhardt MJ, Branston NM, Symon L.

Biochem Soc Trans. 1977;5(1):158-60. No abstract available.

PMID:
408202
45.

The relationship between intensity and duration of cortical ischaemia and reduction of synaptosomal uptake of neurotransmitter in baboons.

Strong AJ, Goodhardt MJ, Branston NM, Bowen DM, Symon L.

Acta Neurol Scand Suppl. 1977;64:372-3. No abstract available.

PMID:
19916
46.

Biochemical indices of brain structure, function and "hypoxia" in cortex from baboons with middle cerebral artery occlusion.

Bowen DM, Goodhardt MJ, Strong AJ, Smith CB, White P, Branston NM, Symon L, Davison AN.

Brain Res. 1976 Dec 3;117(3):503-7. No abstract available.

PMID:
825198

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