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Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway.

Benedikz EK, Bailey D, Cook CNL, Gonçalves-Carneiro D, Buckner MMC, Blair JMA, Wells TJ, Fletcher NF, Goodall M, Flores-Langarica A, Kingsley RA, Madsen J, Teeling J, Johnston SL, MacLennan CA, Balfe P, Henderson IR, Piddock LJV, Cunningham AF, McKeating JA.

Sci Rep. 2019 May 27;9(1):7903. doi: 10.1038/s41598-019-44263-7.


A preliminary service evaluation of a personality disorder case management service.

Graham S, Sullivan K, Briggs L, Goodall M, Iraci Capucinello R.

Personal Ment Health. 2019 May;13(2):65-74. doi: 10.1002/pmh.1439. Epub 2019 Feb 25.


A Glucuronoxylomannan Epitope Exhibits Serotype-Specific Accessibility and Redistributes towards the Capsule Surface during Titanization of the Fungal Pathogen Cryptococcus neoformans.

Probert M, Zhou X, Goodall M, Johnston SA, Bielska E, Ballou ER, May RC.

Infect Immun. 2019 Mar 25;87(4). pii: e00731-18. doi: 10.1128/IAI.00731-18. Print 2019 Apr.


The Unexpected Role of Carbonate Impurities in Polyphosphate Corrosion Inhibition.

Morsch S, Emad S, Farren LA, Goodall MD, Lyon SB, Gibbon SR.

Sci Rep. 2018 Nov 28;8(1):17450. doi: 10.1038/s41598-018-35512-2.


LRRK2 deficiency impairs trans-Golgi to lysosome trafficking and endocytic cargo degradation in human renal proximal tubule epithelial cells.

Lanning NJ, VanOpstall C, Goodall ML, MacKeigan JP, Looyenga BD.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1465-F1477. doi: 10.1152/ajprenal.00009.2018. Epub 2018 Aug 8.


IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates.

Schager AE, Dominguez-Medina CC, Necchi F, Micoli F, Goh YS, Goodall M, Flores-Langarica A, Bobat S, Cook CNL, Arcuri M, Marini A, King LDW, Morris FC, Anderson G, Toellner KM, Henderson IR, López-Macías C, MacLennan CA, Cunningham AF.

MBio. 2018 Mar 6;9(2). pii: e02379-17. doi: 10.1128/mBio.02379-17.


CD103+CD11b+ mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin.

Flores-Langarica A, Müller Luda K, Persson EK, Cook CN, Bobat S, Marshall JL, Dahlgren MW, Hägerbrand K, Toellner KM, Goodall MD, Withers DR, Henderson IR, Johansson Lindbom B, Cunningham AF, Agace WW.

Mucosal Immunol. 2018 May;11(3):681-692. doi: 10.1038/mi.2017.105. Epub 2017 Dec 20.


Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope.

Avnir Y, Prachanronarong KL, Zhang Z, Hou S, Peterson EC, Sui J, Zayed H, Kurella VB, McGuire AT, Stamatatos L, Hilbert BJ, Bohn MF, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Goodall M, Jefferis R, Zhu Q, Kurt Yilmaz N, Schiffer CA, Marasco WA.

Cell Rep. 2017 Dec 12;21(11):3243-3255. doi: 10.1016/j.celrep.2017.11.056.


IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium.

Zhang Y, Dominguez-Medina C, Cumley NJ, Heath JN, Essex SJ, Bobat S, Schager A, Goodall M, Kracker S, Buckley CD, May RC, Kingsley RA, MacLennan CA, López-Macías C, Cunningham AF, Toellner KM.

J Immunol. 2017 Dec 15;199(12):4103-4109. doi: 10.4049/jimmunol.1700952. Epub 2017 Nov 10.


A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81.

Grove J, Hu K, Farquhar MJ, Goodall M, Walker L, Jamshad M, Drummer HE, Bill RM, Balfe P, McKeating JA.

Wellcome Open Res. 2017 Sep 7;2:82. doi: 10.12688/wellcomeopenres.12058.1. eCollection 2017.


NICE guidance on ibrutinib for previously treated chronic lymphocytic leukaemia and untreated chronic lymphocytic leukaemia in the presence of 17p deletion or TP53 mutation.

Mikudina B, Goodall M, Adler AI.

Lancet Oncol. 2017 Mar;18(3):289-290. doi: 10.1016/S1470-2045(17)30062-1. Epub 2017 Jan 25. No abstract available.


Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.

Mulcahy Levy JM, Zahedi S, Griesinger AM, Morin A, Davies KD, Aisner DL, Kleinschmidt-DeMasters BK, Fitzwalter BE, Goodall ML, Thorburn J, Amani V, Donson AM, Birks DK, Mirsky DM, Hankinson TC, Handler MH, Green AL, Vibhakar R, Foreman NK, Thorburn A.

Elife. 2017 Jan 17;6. pii: e19671. doi: 10.7554/eLife.19671.


Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells.

Thorburn J, Staskiewicz L, Goodall ML, Dimberg L, Frankel AE, Ford HL, Thorburn A.

Mol Pharmacol. 2017 Jan;91(1):58-64. Epub 2016 Nov 9.


Autophagy RIPs into cell death.

Goodall ML, Cramer SD, Thorburn A.

Cell Cycle. 2016 Nov 16;15(22):3014-3015. Epub 2016 Aug 30. No abstract available.


Development of a rapid and quantitative lateral flow assay for the simultaneous measurement of serum κ and λ immunoglobulin free light chains (FLC): inception of a new near-patient FLC screening tool.

Campbell JP, Heaney JL, Shemar M, Baldwin D, Griffin AE, Oldridge E, Goodall M, Afzal Z, Plant T, Cobbold M, Jefferis R, Jacobs JF, Hand C, Drayson MT.

Clin Chem Lab Med. 2017 Mar 1;55(3):424-434. doi: 10.1515/cclm-2016-0194.


Autophagy complexes cell death by necroptosis.

Goodall ML, Cramer SD, Thorburn A.

Oncotarget. 2016 Aug 9;7(32):50818-50819. doi: 10.18632/oncotarget.10640. No abstract available.


Cabazitaxel for metastatic hormone-relapsed prostate cancer treated with docetaxel.

Lovett R, Kelly V, Goodall M, Adler AI.

Lancet Oncol. 2016 Jul;17(7):872-873. doi: 10.1016/S1470-2045(16)30165-6. Epub 2016 May 24. No abstract available.


The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis.

Goodall ML, Fitzwalter BE, Zahedi S, Wu M, Rodriguez D, Mulcahy-Levy JM, Green DR, Morgan M, Cramer SD, Thorburn A.

Dev Cell. 2016 May 23;37(4):337-349. doi: 10.1016/j.devcel.2016.04.018.


Humanized mouse G6 anti-idiotypic monoclonal antibody has therapeutic potential against IGHV1-69 germline gene-based B-CLL.

Chang DK, Kurella VB, Biswas S, Avnir Y, Sui J, Wang X, Sun J, Wang Y, Panditrao M, Peterson E, Tallarico A, Fernandes S, Goodall M, Zhu Q, Brown JR, Jefferis R, Marasco WA.

MAbs. 2016 May-Jun;8(4):787-98. doi: 10.1080/19420862.2016.1159365. Epub 2016 Mar 10.


Salivary immunoglobulin free light chains: reference ranges and responses to exercise in young and older adults.

Heaney JL, Gleeson M, Phillips AC, Taylor IM, Drayson MT, Goodall M, He CS, Svendsen IS, Killer SC, Campbell JP.

Exerc Immunol Rev. 2016;22:28-41.


NICE guidance on nintedanib for treating idiopathic pulmonary fibrosis.

Laurenson S, Sidhu R, Goodall M, Adler AI.

Lancet Respir Med. 2016 Mar;4(3):176-7. doi: 10.1016/S2213-2600(16)00022-9. Epub 2016 Jan 27. No abstract available.


Enhanced sialylation of a human chimeric IgG1 variant produced in human and rodent cell lines.

Mimura Y, Kelly RM, Unwin L, Albrecht S, Jefferis R, Goodall M, Mizukami Y, Mimura-Kimura Y, Matsumoto T, Ueoka H, Rudd PM.

J Immunol Methods. 2016 Jan;428:30-6. doi: 10.1016/j.jim.2015.11.009. Epub 2015 Nov 26.


Synthesis of improved lysomotropic autophagy inhibitors.

Wang T, Goodall ML, Gonzales P, Sepulveda M, Martin KR, Gately S, MacKeigan JP.

J Med Chem. 2015 Apr 9;58(7):3025-35. doi: 10.1021/jm501586m. Epub 2015 Mar 27.


Enzymatic enantioselective decarboxylative protonation of heteroaryl malonates.

Lewin R, Goodall M, Thompson ML, Leigh J, Breuer M, Baldenius K, Micklefield J.

Chemistry. 2015 Apr 20;21(17):6557-63. doi: 10.1002/chem.201406014. Epub 2015 Mar 12.


Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion.

Maycotte P, Jones KL, Goodall ML, Thorburn J, Thorburn A.

Mol Cancer Res. 2015 Apr;13(4):651-8. doi: 10.1158/1541-7786.MCR-14-0487. Epub 2015 Jan 8.


Authors' reply to comments made about our article 'Food for thought'.

Gabbay MB, Goodall M, Capewell S, Bowers P, Kennedy LA, Byrne P, Barton GR, Martindale AM; Lay Health trainer Intervention Study (LHtIST) research group.

J Public Health (Oxf). 2015 Dec;37(4):749-50. doi: 10.1093/pubmed/fdu111. Epub 2014 Dec 23. No abstract available.


Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing.

Wells TJ, Whitters D, Sevastsyanovich YR, Heath JN, Pravin J, Goodall M, Browning DF, O'Shea MK, Cranston A, De Soyza A, Cunningham AF, MacLennan CA, Henderson IR, Stockley RA.

J Exp Med. 2014 Aug 25;211(9):1893-904. doi: 10.1084/jem.20132444. Epub 2014 Aug 11.


Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib.

Goodall ML, Wang T, Martin KR, Kortus MG, Kauffman AL, Trent JM, Gately S, MacKeigan JP.

Autophagy. 2014 Jun;10(6):1120-36. doi: 10.4161/auto.28594.


Identifying specific receptors for cargo-mediated autophagy.

Goodall M, Thorburn A.

Cell Res. 2014 Jul;24(7):783-4. doi: 10.1038/cr.2014.56. Epub 2014 May 6.


Overcoming the barriers to the diagnosis and management of chronic fatigue syndrome/ME in primary care: a meta synthesis of qualitative studies.

Bayliss K, Goodall M, Chisholm A, Fordham B, Chew-Graham C, Riste L, Fisher L, Lovell K, Peters S, Wearden A.

BMC Fam Pract. 2014 Mar 7;15:44. doi: 10.1186/1471-2296-15-44.


Food for thought: pilot randomized controlled trial of lay health trainers supporting dietary change to reduce cardiovascular disease in deprived communities.

Goodall M, Barton GR, Bower P, Byrne P, Cade JE, Capewell S, Cleghorn CL, Kennedy LA, Martindale AM, Roberts C, Woolf S, Gabbay MB.

J Public Health (Oxf). 2014 Dec;36(4):635-43. doi: 10.1093/pubmed/fdt112. Epub 2013 Nov 25.


Germinal center B cells govern their own fate via antibody feedback.

Zhang Y, Meyer-Hermann M, George LA, Figge MT, Khan M, Goodall M, Young SP, Reynolds A, Falciani F, Waisman A, Notley CA, Ehrenstein MR, Kosco-Vilbois M, Toellner KM.

J Exp Med. 2013 Mar 11;210(3):457-64. doi: 10.1084/jem.20120150. Epub 2013 Feb 18.


Development of a highly-sensitive multi-plex assay using monoclonal antibodies for the simultaneous measurement of kappa and lambda immunoglobulin free light chains in serum and urine.

Campbell JP, Cobbold M, Wang Y, Goodall M, Bonney SL, Chamba A, Birtwistle J, Plant T, Afzal Z, Jefferis R, Drayson MT.

J Immunol Methods. 2013 May 31;391(1-2):1-13. doi: 10.1016/j.jim.2013.01.014. Epub 2013 Feb 4.


Purification of antibodies to O antigen of Salmonella Typhimurium from human serum by affinity chromatography.

O'Shaughnessy CM, Micoli F, Gavini M, Goodall M, Cobbold M, Saul A, Maclennan CA.

J Immunol Methods. 2013 Jan 31;387(1-2):199-210. doi: 10.1016/j.jim.2012.10.015. Epub 2012 Nov 8.


Hepatoma polarization limits CD81 and hepatitis C virus dynamics.

Harris HJ, Clerte C, Farquhar MJ, Goodall M, Hu K, Rassam P, Dosset P, Wilson GK, Balfe P, Ijzendoorn SC, Milhiet PE, McKeating JA.

Cell Microbiol. 2013 Mar;15(3):430-45. doi: 10.1111/cmi.12047. Epub 2012 Nov 20.


Structural and functional evaluation of branched myofibers lacking intermediate filaments.

Goodall MH, Ward CW, Pratt SJP, Bloch RJ, Lovering RM.

Am J Physiol Cell Physiol. 2012 Jul 15;303(2):C224-32. doi: 10.1152/ajpcell.00136.2012. Epub 2012 May 16.


Thermal bifunctionality of bacterial phenylalanine aminomutase and ammonia lyase enzymes.

Chesters C, Wilding M, Goodall M, Micklefield J.

Angew Chem Int Ed Engl. 2012 Apr 27;51(18):4344-8. doi: 10.1002/anie.201200669. Epub 2012 Mar 27. No abstract available.


An in vivo rodent model of contraction-induced injury and non-invasive monitoring of recovery.

Lovering RM, Roche JA, Goodall MH, Clark BB, McMillan A.

J Vis Exp. 2011 May 11;(51). pii: 2782. doi: 10.3791/2782.


Increasing heart-health lifestyles in deprived communities: economic evaluation of lay health trainers.

Barton GR, Goodall M, Bower P, Woolf S, Capewell S, Gabbay MB.

J Eval Clin Pract. 2012 Aug;18(4):835-40. doi: 10.1111/j.1365-2753.2011.01686.x. Epub 2011 Apr 24.


Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection.

Bobat S, Flores-Langarica A, Hitchcock J, Marshall JL, Kingsley RA, Goodall M, Gil-Cruz C, Serre K, Leyton DL, Letran SE, Gaspal F, Chester R, Chamberlain JL, Dougan G, López-Macías C, Henderson IR, Alexander J, MacLennan IC, Cunningham AF.

Eur J Immunol. 2011 Jun;41(6):1606-18. doi: 10.1002/eji.201041089. Epub 2011 May 10.


Healthy eating in early years settings: a review of current national to local guidance for North West England.

Bristow K, Capewell S, Abba K, Goodall M, Lloyd-Williams F.

Public Health Nutr. 2011 Jun;14(6):1008-16. doi: 10.1017/S1368980010003836. Epub 2011 Feb 3. Review.


Novel function of cardiac protein kinase D1 as a dynamic regulator of Ca2+ sensitivity of contraction.

Goodall MH, Wardlow RD 2nd, Goldblum RR, Ziman A, Lederer WJ, Randall W, Rogers TB.

J Biol Chem. 2010 Dec 31;285(53):41686-700. doi: 10.1074/jbc.M110.179648. Epub 2010 Nov 1.


Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults.

MacLennan CA, Gilchrist JJ, Gordon MA, Cunningham AF, Cobbold M, Goodall M, Kingsley RA, van Oosterhout JJ, Msefula CL, Mandala WL, Leyton DL, Marshall JL, Gondwe EN, Bobat S, López-Macías C, Doffinger R, Henderson IR, Zijlstra EE, Dougan G, Drayson MT, MacLennan IC, Molyneux ME.

Science. 2010 Apr 23;328(5977):508-12. doi: 10.1126/science.1180346.


Claudin association with CD81 defines hepatitis C virus entry.

Harris HJ, Davis C, Mullins JG, Hu K, Goodall M, Farquhar MJ, Mee CJ, McCaffrey K, Young S, Drummer H, Balfe P, McKeating JA.

J Biol Chem. 2010 Jul 2;285(27):21092-102. doi: 10.1074/jbc.M110.104836. Epub 2010 Apr 7.


Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in Africans.

Gondwe EN, Molyneux ME, Goodall M, Graham SM, Mastroeni P, Drayson MT, MacLennan CA.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3070-5. doi: 10.1073/pnas.0910497107. Epub 2010 Jan 28.


The APPLe study: a randomized, community-based, placebo-controlled trial of azithromycin for the prevention of preterm birth, with meta-analysis.

van den Broek NR, White SA, Goodall M, Ntonya C, Kayira E, Kafulafula G, Neilson JP.

PLoS Med. 2009 Dec;6(12):e1000191. doi: 10.1371/journal.pmed.1000191. Epub 2009 Dec 1.


Chimeric IgG4 PR3-ANCA induces selective inflammatory responses from neutrophils through engagement of Fcgamma receptors.

Hussain A, Pankhurst T, Goodall M, Colman R, Jefferis R, Savage CO, Williams JM.

Immunology. 2009 Oct;128(2):236-44. doi: 10.1111/j.1365-2567.2009.03108.x.


Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases.

Okrasa K, Levy C, Wilding M, Goodall M, Baudendistel N, Hauer B, Leys D, Micklefield J.

Angew Chem Int Ed Engl. 2009;48(41):7691-4. doi: 10.1002/anie.200904112. No abstract available.


Measurement of human serum IgD levels.

Overed-Sayer CL, Mosedale DE, Goodall M, Grainger DJ.

Curr Protoc Immunol. 2009 Apr;Chapter 2:Unit 2.9B. doi: 10.1002/0471142735.im0209bs85.


IgG1 heavy chain-coding gene polymorphism (G1m allotypes) and development of antibodies-to-infliximab.

Magdelaine-Beuzelin C, Vermeire S, Goodall M, Baert F, Noman M, Assche GV, Ohresser M, Degenne D, Dugoujon JM, Jefferis R, Rutgeerts P, Lefranc MP, Watier H.

Pharmacogenet Genomics. 2009 May;19(5):383-7. doi: 10.1097/FPC.0b013e32832a06bf.


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