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Items: 1 to 50 of 119

1.

Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT.

Cursons J, Pillman KA, Scheer KG, Gregory PA, Foroutan M, Hediyeh-Zadeh S, Toubia J, Crampin EJ, Goodall GJ, Bracken CP, Davis MJ.

Cell Syst. 2018 Jul 6. pii: S2405-4712(18)30237-0. doi: 10.1016/j.cels.2018.05.019. [Epub ahead of print]

2.

FOXP3 and miR-155 cooperate to control the invasive potential of human breast cancer cells by down regulating ZEB2 independently of ZEB1.

Brown CY, Dayan S, Wong SW, Kaczmarek A, Hope CM, Pederson SM, Arnet V, Goodall GJ, Russell D, Sadlon TJ, Barry SC.

Oncotarget. 2018 Jun 12;9(45):27708-27727. doi: 10.18632/oncotarget.25523. eCollection 2018 Jun 12.

3.

miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking.

Pillman KA, Phillips CA, Roslan S, Toubia J, Dredge BK, Bert AG, Lumb R, Neumann DP, Li X, Conn SJ, Liu D, Bracken CP, Lawrence DM, Stylianou N, Schreiber AW, Tilley WD, Hollier BG, Khew-Goodall Y, Selth LA, Goodall GJ, Gregory PA.

EMBO J. 2018 Jul 2;37(13). pii: e99016. doi: 10.15252/embj.201899016. Epub 2018 Jun 5.

4.

Clinical Utility of a STAT3-Regulated miRNA-200 Family Signature with Prognostic Potential in Early Gastric Cancer.

Yu L, Wu D, Gao H, Balic JJ, Tsykin A, Han TS, Liu YD, Kennedy CL, Li JK, Mao JQ, Tan P, Oshima M, Goodall GJ, Jenkins BJ.

Clin Cancer Res. 2018 Mar 15;24(6):1459-1472. doi: 10.1158/1078-0432.CCR-17-2485. Epub 2018 Jan 12.

PMID:
29330205
5.

A Highly Efficient Strategy for Overexpressing circRNAs.

Liu D, Conn V, Goodall GJ, Conn SJ.

Methods Mol Biol. 2018;1724:97-105. doi: 10.1007/978-1-4939-7562-4_8.

PMID:
29322443
6.

LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.

Boulding T, McCuaig RD, Tan A, Hardy K, Wu F, Dunn J, Kalimutho M, Sutton CR, Forwood JK, Bert AG, Goodall GJ, Malik L, Yip D, Dahlstrom JE, Zafar A, Khanna KK, Rao S.

Sci Rep. 2018 Jan 8;8(1):73. doi: 10.1038/s41598-017-17913-x.

7.

miR-222 isoforms are differentially regulated by type-I interferon.

Nejad C, Pillman KA, Siddle KJ, Pépin G, Änkö ML, McCoy CE, Beilharz TH, Quintana-Murci L, Goodall GJ, Bracken CP, Gantier MP.

RNA. 2018 Mar;24(3):332-341. doi: 10.1261/rna.064550.117. Epub 2017 Dec 20.

PMID:
29263133
8.

Naturally existing isoforms of miR-222 have distinct functions.

Yu F, Pillman KA, Neilsen CT, Toubia J, Lawrence DM, Tsykin A, Gantier MP, Callen DF, Goodall GJ, Bracken CP.

Nucleic Acids Res. 2017 Nov 2;45(19):11371-11385. doi: 10.1093/nar/gkx788.

9.

Regulation of splicing and circularisation of RNA in epithelial mesenchymal plasticity.

Neumann DP, Goodall GJ, Gregory PA.

Semin Cell Dev Biol. 2018 Mar;75:50-60. doi: 10.1016/j.semcdb.2017.08.008. Epub 2017 Aug 5. Review.

PMID:
28789987
10.

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2.

Das R, Gregory PA, Fernandes RC, Denis I, Wang Q, Townley SL, Zhao SG, Hanson AR, Pickering MA, Armstrong HK, Lokman NA, Ebrahimie E, Davicioni E, Jenkins RB, Karnes RJ, Ross AE, Den RB, Klein EA, Chi KN, Ramshaw HS, Williams ED, Zoubeidi A, Goodall GJ, Feng FY, Butler LM, Tilley WD, Selth LA.

Cancer Res. 2017 Feb 15;77(4):1021-1034. doi: 10.1158/0008-5472.CAN-16-2529. Epub 2016 Dec 23.

11.

A network-biology perspective of microRNA function and dysfunction in cancer.

Bracken CP, Scott HS, Goodall GJ.

Nat Rev Genet. 2016 Dec;17(12):719-732. doi: 10.1038/nrg.2016.134. Epub 2016 Oct 31. Review.

PMID:
27795564
12.

Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia.

Narayan N, Morenos L, Phipson B, Willis SN, Brumatti G, Eggers S, Lalaoui N, Brown LM, Kosasih HJ, Bartolo RC, Zhou L, Catchpoole D, Saffery R, Oshlack A, Goodall GJ, Ekert PG.

Leukemia. 2017 Apr;31(4):808-820. doi: 10.1038/leu.2016.279. Epub 2016 Oct 14.

PMID:
27740637
13.

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

Selth LA, Das R, Townley SL, Coutinho I, Hanson AR, Centenera MM, Stylianou N, Sweeney K, Soekmadji C, Jovanovic L, Nelson CC, Zoubeidi A, Butler LM, Goodall GJ, Hollier BG, Gregory PA, Tilley WD.

Oncogene. 2017 Jan 5;36(1):24-34. doi: 10.1038/onc.2016.185. Epub 2016 Jun 6.

PMID:
27270433
14.

Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits.

Pal B, Chen Y, Bert A, Hu Y, Sheridan JM, Beck T, Shi W, Satterley K, Jamieson P, Goodall GJ, Lindeman GJ, Smyth GK, Visvader JE.

Breast Cancer Res. 2015 Jun 18;17:85. doi: 10.1186/s13058-015-0585-0.

15.

Network-Based Approaches to Understand the Roles of miR-200 and Other microRNAs in Cancer.

Bracken CP, Khew-Goodall Y, Goodall GJ.

Cancer Res. 2015 Jul 1;75(13):2594-9. doi: 10.1158/0008-5472.CAN-15-0287. Epub 2015 Jun 11. Review.

16.

p53 Represses the Oncogenic Sno-MiR-28 Derived from a SnoRNA.

Yu F, Bracken CP, Pillman KA, Lawrence DM, Goodall GJ, Callen DF, Neilsen PM.

PLoS One. 2015 Jun 10;10(6):e0129190. doi: 10.1371/journal.pone.0129190. eCollection 2015.

17.

MicroRNA networks regulated by all-trans retinoic acid and Lapatinib control the growth, survival and motility of breast cancer cells.

Fisher JN, Terao M, Fratelli M, Kurosaki M, Paroni G, Zanetti A, Gianni M, Bolis M, Lupi M, Tsykin A, Goodall GJ, Garattini E.

Oncotarget. 2015 May 30;6(15):13176-200.

18.

The RNA binding protein quaking regulates formation of circRNAs.

Conn SJ, Pillman KA, Toubia J, Conn VM, Salmanidis M, Phillips CA, Roslan S, Schreiber AW, Gregory PA, Goodall GJ.

Cell. 2015 Mar 12;160(6):1125-34. doi: 10.1016/j.cell.2015.02.014.

19.

The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking.

Belle L, Ali N, Lonic A, Li X, Paltridge JL, Roslan S, Herrmann D, Conway JR, Gehling FK, Bert AG, Crocker LA, Tsykin A, Farshid G, Goodall GJ, Timpson P, Daly RJ, Khew-Goodall Y.

Sci Signal. 2015 Feb 17;8(364):ra18. doi: 10.1126/scisignal.2005547.

PMID:
25690013
20.

Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin.

Thomson DW, Pillman KA, Anderson ML, Lawrence DM, Toubia J, Goodall GJ, Bracken CP.

Nucleic Acids Res. 2015 Jan;43(1):470-81. doi: 10.1093/nar/gku1242. Epub 2014 Dec 1.

21.

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes.

Sanij E, Diesch J, Lesmana A, Poortinga G, Hein N, Lidgerwood G, Cameron DP, Ellul J, Goodall GJ, Wong LH, Dhillon AS, Hamdane N, Rothblum LI, Pearson RB, Haviv I, Moss T, Hannan RD.

Genome Res. 2015 Feb;25(2):201-12. doi: 10.1101/gr.176115.114. Epub 2014 Dec 1.

22.

Identifying direct miRNA-mRNA causal regulatory relationships in heterogeneous data.

Zhang J, Le TD, Liu L, Liu B, He J, Goodall GJ, Li J.

J Biomed Inform. 2014 Dec;52:438-47. doi: 10.1016/j.jbi.2014.08.005. Epub 2014 Aug 30.

23.

Evidence that meningeal mast cells can worsen stroke pathology in mice.

Arac A, Grimbaldeston MA, Nepomuceno AR, Olayiwola O, Pereira MP, Nishiyama Y, Tsykin A, Goodall GJ, Schlecht U, Vogel H, Tsai M, Galli SJ, Bliss TM, Steinberg GK.

Am J Pathol. 2014 Sep;184(9):2493-504. doi: 10.1016/j.ajpath.2014.06.003.

24.

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion.

Bracken CP, Li X, Wright JA, Lawrence DM, Pillman KA, Salmanidis M, Anderson MA, Dredge BK, Gregory PA, Tsykin A, Neilsen C, Thomson DW, Bert AG, Leerberg JM, Yap AS, Jensen KB, Khew-Goodall Y, Goodall GJ.

EMBO J. 2014 Sep 17;33(18):2040-56. doi: 10.15252/embj.201488641. Epub 2014 Jul 28.

25.

Inferring condition-specific miRNA activity from matched miRNA and mRNA expression data.

Zhang J, Le TD, Liu L, Liu B, He J, Goodall GJ, Li J.

Bioinformatics. 2014 Nov 1;30(21):3070-7. doi: 10.1093/bioinformatics/btu489. Epub 2014 Jul 23.

26.

Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells.

Zafar A, Wu F, Hardy K, Li J, Tu WJ, McCuaig R, Harris J, Khanna KK, Attema J, Gregory PA, Goodall GJ, Harrington K, Dahlstrom JE, Boulding T, Madden R, Tan A, Milburn PJ, Rao S.

Mol Cell Biol. 2014 Aug;34(16):2961-80. doi: 10.1128/MCB.01693-13. Epub 2014 Jun 2.

27.

Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition.

Kolesnikoff N, Attema JL, Roslan S, Bert AG, Schwarz QP, Gregory PA, Goodall GJ.

J Biol Chem. 2014 Apr 18;289(16):11194-205. doi: 10.1074/jbc.M113.529172. Epub 2014 Mar 13.

28.

Understanding principles of miRNA target recognition and function through integrated biological and bioinformatics approaches.

Carroll AP, Goodall GJ, Liu B.

Wiley Interdiscip Rev RNA. 2014 May-Jun;5(3):361-79. doi: 10.1002/wrna.1217. Epub 2014 Jan 23. Review.

PMID:
24459110
29.

Enhanced expression of transferrin receptor 1 contributes to oncogenic signalling by sphingosine kinase 1.

Pham DH, Powell JA, Gliddon BL, Moretti PA, Tsykin A, Van der Hoek M, Kenyon R, Goodall GJ, Pitson SM.

Oncogene. 2014 Nov 27;33(48):5559-68. doi: 10.1038/onc.2013.502. Epub 2013 Nov 25.

PMID:
24276247
30.

Identification of an enhancer that increases miR-200b~200a~429 gene expression in breast cancer cells.

Attema JL, Bert AG, Lim YY, Kolesnikoff N, Lawrence DM, Pillman KA, Smith E, Drew PA, Khew-Goodall Y, Shannon F, Goodall GJ.

PLoS One. 2013 Sep 25;8(9):e75517. doi: 10.1371/journal.pone.0075517. eCollection 2013.

31.

MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways.

Li X, Roslan S, Johnstone CN, Wright JA, Bracken CP, Anderson M, Bert AG, Selth LA, Anderson RL, Goodall GJ, Gregory PA, Khew-Goodall Y.

Oncogene. 2014 Jul 31;33(31):4077-88. doi: 10.1038/onc.2013.370. Epub 2013 Sep 16.

PMID:
24037528
32.

Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib.

Giles KM, Kalinowski FC, Candy PA, Epis MR, Zhang PM, Redfern AD, Stuart LM, Goodall GJ, Leedman PJ.

Mol Cancer Ther. 2013 Nov;12(11):2541-58. doi: 10.1158/1535-7163.MCT-13-0170. Epub 2013 Sep 11.

33.

Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27.

Young JA, Ting KK, Li J, Moller T, Dunn L, Lu Y, Moses J, Prado-Lourenço L, Khachigian LM, Ng M, Gregory PA, Goodall GJ, Tsykin A, Lichtenstein I, Hahn CN, Tran N, Shackel N, Kench JG, McCaughan G, Vadas MA, Gamble JR.

Blood. 2013 Oct 17;122(16):2911-9. doi: 10.1182/blood-2012-12-473017. Epub 2013 Sep 5. Erratum in: Blood. 2014 Nov 6;124(19):3034.

34.

Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer.

Roy SS, Gonugunta VK, Bandyopadhyay A, Rao MK, Goodall GJ, Sun LZ, Tekmal RR, Vadlamudi RK.

Oncogene. 2014 Jul 10;33(28):3707-16. doi: 10.1038/onc.2013.332. Epub 2013 Aug 26.

35.

Hoxb8 regulates expression of microRNAs to control cell death and differentiation.

Salmanidis M, Brumatti G, Narayan N, Green BD, van den Bergen JA, Sandow JJ, Bert AG, Silke N, Sladic R, Puthalakath H, Rohrbeck L, Okamoto T, Bouillet P, Herold MJ, Goodall GJ, Jabbour AM, Ekert PG.

Cell Death Differ. 2013 Oct;20(10):1370-80. doi: 10.1038/cdd.2013.92. Epub 2013 Jul 19.

36.

Circulating microRNAs predict biochemical recurrence in prostate cancer patients.

Selth LA, Townley SL, Bert AG, Stricker PD, Sutherland PD, Horvath LG, Goodall GJ, Butler LM, Tilley WD.

Br J Cancer. 2013 Aug 6;109(3):641-50. doi: 10.1038/bjc.2013.369. Epub 2013 Jul 11.

37.

Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state.

Lim YY, Wright JA, Attema JL, Gregory PA, Bert AG, Smith E, Thomas D, Lopez AF, Drew PA, Khew-Goodall Y, Goodall GJ.

J Cell Sci. 2013 May 15;126(Pt 10):2256-66. doi: 10.1242/jcs.122275. Epub 2013 Mar 22.

38.

Inferring microRNA and transcription factor regulatory networks in heterogeneous data.

Le TD, Liu L, Liu B, Tsykin A, Goodall GJ, Satou K, Li J.

BMC Bioinformatics. 2013 Mar 11;14:92. doi: 10.1186/1471-2105-14-92.

39.
40.

Discovering functional microRNA-mRNA regulatory modules in heterogeneous data.

Liu B, Liu L, Tsykin A, Goodall GJ, Cairns MJ, Li J.

Adv Exp Med Biol. 2013;774:267-90. doi: 10.1007/978-94-007-5590-1_14.

PMID:
23377978
41.

Inferring microRNA-mRNA causal regulatory relationships from expression data.

Le TD, Liu L, Tsykin A, Goodall GJ, Liu B, Sun BY, Li J.

Bioinformatics. 2013 Mar 15;29(6):765-71. doi: 10.1093/bioinformatics/btt048. Epub 2013 Jan 30.

PMID:
23365408
42.

On measuring miRNAs after transient transfection of mimics or antisense inhibitors.

Thomson DW, Bracken CP, Szubert JM, Goodall GJ.

PLoS One. 2013;8(1):e55214. doi: 10.1371/journal.pone.0055214. Epub 2013 Jan 24.

43.

Matrigel basement membrane matrix influences expression of microRNAs in cancer cell lines.

Price KJ, Tsykin A, Giles KM, Sladic RT, Epis MR, Ganss R, Goodall GJ, Leedman PJ.

Biochem Biophys Res Commun. 2012 Oct 19;427(2):343-8. doi: 10.1016/j.bbrc.2012.09.059. Epub 2012 Sep 18.

PMID:
23000157
44.

IsomiRs--the overlooked repertoire in the dynamic microRNAome.

Neilsen CT, Goodall GJ, Bracken CP.

Trends Genet. 2012 Nov;28(11):544-9. doi: 10.1016/j.tig.2012.07.005. Epub 2012 Aug 8. Review.

PMID:
22883467
45.

ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression.

Ahn YH, Gibbons DL, Chakravarti D, Creighton CJ, Rizvi ZH, Adams HP, Pertsemlidis A, Gregory PA, Wright JA, Goodall GJ, Flores ER, Kurie JM.

J Clin Invest. 2012 Sep;122(9):3170-83. doi: 10.1172/JCI63608. Epub 2012 Aug 1.

46.

Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.

Neilsen PM, Noll JE, Mattiske S, Bracken CP, Gregory PA, Schulz RB, Lim SP, Kumar R, Suetani RJ, Goodall GJ, Callen DF.

Oncogene. 2013 Jun 13;32(24):2992-3000. doi: 10.1038/onc.2012.305. Epub 2012 Jul 16.

PMID:
22797073
47.

Stromal miR-320 keeps an oncogenic secretome in check.

Khew-Goodall Y, Goodall GJ.

Nat Cell Biol. 2012 Feb 2;14(2):124-5. doi: 10.1038/ncb2431. No abstract available.

PMID:
22298040
48.

A microRNA that limits metastatic colonisation and endothelial recruitment.

Khew-Goodall Y, Goodall GJ.

EMBO J. 2012 Feb 15;31(4):786-7. doi: 10.1038/emboj.2011.504. Epub 2012 Feb 15. No abstract available.

49.

FOXP3 and FOXP3-regulated microRNAs suppress SATB1 in breast cancer cells.

McInnes N, Sadlon TJ, Brown CY, Pederson S, Beyer M, Schultze JL, McColl S, Goodall GJ, Barry SC.

Oncogene. 2012 Feb 23;31(8):1045-54. doi: 10.1038/onc.2011.293. Epub 2011 Jul 11.

PMID:
21743493
50.

Experimental strategies for microRNA target identification.

Thomson DW, Bracken CP, Goodall GJ.

Nucleic Acids Res. 2011 Sep 1;39(16):6845-53. doi: 10.1093/nar/gkr330. Epub 2011 Jun 7. Review.

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