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The acceptability of alcohol intoxication management services to users: A mixed methods study.

Irving A, Buykx P, Amos Y, Goodacre S, Moore SC, O'Cathain A.

Drug Alcohol Rev. 2019 Nov 26. doi: 10.1111/dar.13002. [Epub ahead of print]


Thromboprophylaxis in lower limb immobilisation after injury (TiLLI).

Horner D, Goodacre S, Pandor A, Nokes T, Keenan J, Hunt B, Davis S, Stevens JW, Hogg K.

Emerg Med J. 2019 Nov 6. pii: emermed-2019-208944. doi: 10.1136/emermed-2019-208944. [Epub ahead of print]


Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy: protocol for the mixed-methods observational 'Collaborate' project.

Noble AJ, Mathieson A, Ridsdale L, Holmes EA, Morgan M, McKinlay A, Dickson JM, Jackson M, Hughes DA, Goodacre S, Marson AG.

BMJ Open. 2019 Nov 2;9(11):e031696. doi: 10.1136/bmjopen-2019-031696.


Pharmacological thromboprophylaxis to prevent venous thromboembolism in patients with temporary lower limb immobilization after injury: systematic review and network meta-analysis.

Horner D, Stevens JW, Pandor A, Nokes T, Keenan J, de Wit K, Goodacre S.

J Thromb Haemost. 2019 Oct 26. doi: 10.1111/jth.14666. [Epub ahead of print]


Progression criteria in trials with an internal pilot: an audit of publicly funded randomised controlled trials.

Herbert E, Julious SA, Goodacre S.

Trials. 2019 Aug 9;20(1):493. doi: 10.1186/s13063-019-3578-y.


The 4 'A's test for detecting delirium in acute medical patients: a diagnostic accuracy study.

MacLullich AM, Shenkin SD, Goodacre S, Godfrey M, Hanley J, Stíobhairt A, Lavender E, Boyd J, Stephen J, Weir C, MacRaild A, Steven J, Black P, Diernberger K, Hall P, Tieges Z, Fox C, Anand A, Young J, Siddiqi N, Gray A.

Health Technol Assess. 2019 Aug;23(40):1-194. doi: 10.3310/hta23400.


Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method.

Shenkin SD, Fox C, Godfrey M, Siddiqi N, Goodacre S, Young J, Anand A, Gray A, Hanley J, MacRaild A, Steven J, Black PL, Tieges Z, Boyd J, Stephen J, Weir CJ, MacLullich AMJ.

BMC Med. 2019 Jul 24;17(1):138. doi: 10.1186/s12916-019-1367-9.


Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927.

Labadie SS, Li J, Blake RA, Chang JH, Goodacre S, Hartman SJ, Liang W, Kiefer JR, Kleinheinz T, Lai T, Liao J, Ortwine DF, Mody V, Ray NC, Roussel F, Vinogradova M, Yeap SK, Zhang B, Zheng X, Zbieg JR, Liang J, Wang X.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2090-2093. doi: 10.1016/j.bmcl.2019.07.013. Epub 2019 Jul 6.


Diagnosis of Pulmonary Embolism During Pregnancy.

Goodacre S, Hunt B, Nelson-Piercy C.

Ann Intern Med. 2019 Jul 16;171(2):146-147. doi: 10.7326/L19-0190. No abstract available.


Diagnosis of Suspected Pulmonary Embolism in Pregnancy.

Goodacre S, Hunt BJ, Nelson-Piercy C.

N Engl J Med. 2019 Jun 20;380(25):e49. doi: 10.1056/NEJMc1905283. No abstract available.


Amblypygid-fungal interactions: The whip spider exoskeleton as a substrate for fungal growth.

Gibbons AT, Idnurm A, Seiter M, Dyer PS, Kokolski M, Goodacre SL, Gorb SN, Wolff JO.

Fungal Biol. 2019 Jul;123(7):497-506. doi: 10.1016/j.funbio.2019.05.003. Epub 2019 May 10.


Developing new ways of measuring the quality and impact of ambulance service care: the PhOEBE mixed-methods research programme.

Turner J, Siriwardena AN, Coster J, Jacques R, Irving A, Crum A, Gorrod HB, Nicholl J, Phung VH, Togher F, Wilson R, O’Cathain A, Booth A, Bradbury D, Goodacre S, Spaight A, Shewan J, Pilbery R, Fall D, Marsh M, Broadway-Parkinson A, Lyons R, Snooks H, Campbell M.

Southampton (UK): NIHR Journals Library; 2019 Apr.


The UK's pandemic influenza research portfolio: a model for future research on emerging infections.

Simpson CR, Beever D, Challen K, De Angelis D, Fragaszy E, Goodacre S, Hayward A, Lim WS, Rubin GJ, Semple MG, Knight M; NIHR hibernated influenza studies collaborative group.

Lancet Infect Dis. 2019 Aug;19(8):e295-e300. doi: 10.1016/S1473-3099(18)30786-2. Epub 2019 Apr 18. Review.


Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling.

Zak M, Hanan EJ, Lupardus P, Brown DG, Robinson C, Siu M, Lyssikatos JP, Romero FA, Zhao G, Kellar T, Mendonca R, Ray NC, Goodacre SC, Crackett PH, McLean N, Hurley CA, Yuen PW, Cheng YX, Liu X, Liimatta M, Kohli PB, Nonomiya J, Salmon G, Buckley G, Lloyd J, Gibbons P, Ghilardi N, Kenny JR, Johnson A.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1522-1531. doi: 10.1016/j.bmcl.2019.04.008. Epub 2019 Apr 4.


The Reality of Pain Scoring in the Emergency Department: Findings From a Multiple Case Study Design.

Sampson FC, Goodacre SW, O'Cathain A.

Ann Emerg Med. 2019 Oct;74(4):538-548. doi: 10.1016/j.annemergmed.2019.02.018. Epub 2019 Apr 5.


Assessing Treatment Fidelity within an Epilepsy Randomized Controlled Trial: Seizure First Aid Training for People with Epilepsy Who Visit Emergency Departments.

Noble AJ, Snape D, Ridsdale L, Morgan M, Nevitt SJ, Goodacre S, Marson A.

Behav Neurol. 2019 Feb 3;2019:5048794. doi: 10.1155/2019/5048794. eCollection 2019.


Decision-analysis modelling of the effects of thromboprophylaxis for people with lower limb immobilisation for injury.

Davis S, Goodacre S, Pandor A, Horner D, Stevens JW, de Wit K, Hunt BJ.

Br J Haematol. 2019 Jul;186(1):166-168. doi: 10.1111/bjh.15748. Epub 2019 Jan 29. No abstract available.


Individual risk factors predictive of venous thromboembolism in patients with temporary lower limb immobilization due to injury: a systematic review.

Horner D, Pandor A, Goodacre S, Clowes M, Hunt BJ.

J Thromb Haemost. 2019 Feb;17(2):329-344. doi: 10.1111/jth.14367. Epub 2019 Feb 7.


Impact of the new medical examiner role on patient safety.

Fletcher A, Coster J, Goodacre S.

BMJ. 2018 Dec 14;363:k5166. doi: 10.1136/bmj.k5166. No abstract available.


Prognostic models for identifying risk of poor outcome in people with acute ankle sprains: the SPRAINED development and external validation study.

Keene DJ, Schlüssel MM, Thompson J, Hagan DA, Williams MA, Byrne C, Goodacre S, Cooke M, Gwilym S, Hormbrey P, Bostock J, Haywood K, Wilson D, Collins GS, Lamb SE.

Health Technol Assess. 2018 Nov;22(64):1-112. doi: 10.3310/hta22640.


Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma.

Dengler HS, Wu X, Peng I, Rinderknecht CH, Kwon Y, Suto E, Kohli PB, Liimatta M, Barrett K, Lloyd J, Cain G, Briggs M, Addo S, Salmon G, Ubhayakar S, Deshmukh G, Shahidi-Latham SK, Quiason-Huynh CM, Jackman J, Liu J, Ray NC, Goodacre SC, Johnson A, McKenzie BS, Lee WP, Zak M, Kenny JR, Ghilardi N.

Sci Transl Med. 2018 Nov 21;10(468). pii: eaao2151. doi: 10.1126/scitranslmed.aao2151.


Development and prospective external validation of a tool to predict poor recovery at 9 months after acute ankle sprain in UK emergency departments: the SPRAINED prognostic model.

Schlussel MM, Keene DJ, Collins GS, Bostock J, Byrne C, Goodacre S, Gwilym S, Hagan DA, Haywood K, Thompson J, Williams MA, Lamb SE; SPRAINED study team.

BMJ Open. 2018 Nov 5;8(11):e022802. doi: 10.1136/bmjopen-2018-022802.


Do all HEART Scores beat the same: evaluating the interoperator reliability of the HEART Score.

Niven WGP, Wilson D, Goodacre S, Robertson A, Green SJ, Harris T.

Emerg Med J. 2018 Dec;35(12):732-738. doi: 10.1136/emermed-2018-207540. Epub 2018 Sep 14.


Selecting pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging: the DiPEP diagnostic study with decision-analysis modelling.

Goodacre S, Horspool K, Shephard N, Pollard D, Hunt BJ, Fuller G, Nelson-Piercy C, Knight M, Thomas S, Lecky F, Cohen J.

Health Technol Assess. 2018 Aug;22(47):1-230. doi: 10.3310/hta22470.


Prosthetic complications with implant prostheses (2001-2017).

Goodacre BJ, Goodacre SE, Goodacre CJ.

Eur J Oral Implantol. 2018;11 Suppl 1:S27-S36.


Interventions to improve patient flow in emergency departments: an umbrella review.

De Freitas L, Goodacre S, O'Hara R, Thokala P, Hariharan S.

Emerg Med J. 2018 Oct;35(10):626-637. doi: 10.1136/emermed-2017-207263. Epub 2018 Aug 9. Review.


The ACUTE (Ambulance CPAP: Use, Treatment effect and economics) feasibility study: a pilot randomised controlled trial of prehospital CPAP for acute respiratory failure.

Fuller GW, Goodacre S, Keating S, Perkins G, Ward M, Rosser A, Gunson I, Miller J, Bradburn M, Thokala P, Harris T, Carson A, Marsh M, Cooper C.

Pilot Feasibility Stud. 2018 Jun 18;4:86. doi: 10.1186/s40814-018-0281-9. eCollection 2018.


The DiPEP study: an observational study of the diagnostic accuracy of clinical assessment, D-dimer and chest x-ray for suspected pulmonary embolism in pregnancy and postpartum.

Goodacre S, Horspool K, Nelson-Piercy C, Knight M, Shephard N, Lecky F, Thomas S, Hunt BJ, Fuller G; DiPEP research group.

BJOG. 2019 Feb;126(3):383-392. doi: 10.1111/1471-0528.15286. Epub 2018 Jun 14.


Conservation of a pH-sensitive structure in the C-terminal region of spider silk extends across the entire silk gene family.

Strickland M, Tudorica V, Řezáč M, Thomas NR, Goodacre SL.

Heredity (Edinb). 2018 Jun;120(6):574-580. doi: 10.1038/s41437-018-0050-9. Epub 2018 Feb 15.


Protocol for validation of the 4AT, a rapid screening tool for delirium: a multicentre prospective diagnostic test accuracy study.

Shenkin SD, Fox C, Godfrey M, Siddiqi N, Goodacre S, Young J, Anand A, Gray A, Smith J, Ryan T, Hanley J, MacRaild A, Steven J, Black PL, Boyd J, Weir CJ, MacLullich AM.

BMJ Open. 2018 Feb 10;8(2):e015572. doi: 10.1136/bmjopen-2016-015572.


The DiPEP (Diagnosis of PE in Pregnancy) biomarker study: An observational cohort study augmented with additional cases to determine the diagnostic utility of biomarkers for suspected venous thromboembolism during pregnancy and puerperium.

Hunt BJ, Parmar K, Horspool K, Shephard N, Nelson-Piercy C, Goodacre S; DiPEP research group.

Br J Haematol. 2018 Mar;180(5):694-704. doi: 10.1111/bjh.15102. Epub 2018 Jan 23.


Managing alcohol-related attendances in emergency care: can diversion to bespoke services lessen the burden?

Irving A, Goodacre S, Blake J, Allen D, Moore SC.

Emerg Med J. 2018 Feb;35(2):79-82. doi: 10.1136/emermed-2016-206451. Epub 2017 Nov 28.


Bypassing nearest hospital for more distant neuroscience care in head-injured adults with suspected traumatic brain injury: findings of the head injury transportation straight to neurosurgery (HITS-NS) pilot cluster randomised trial.

Lecky FE, Russell W, McClelland G, Pennington E, Fuller G, Goodacre S, Han K, Curran A, Holliman D, Chapman N, Freeman J, Byers S, Mason S, Potter H, Coats T, Mackway-Jones K, Peters M, Shewan J.

BMJ Open. 2017 Oct 5;7(10):e016355. doi: 10.1136/bmjopen-2017-016355.


Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.

Liang J, Van Abbema A, Balazs M, Barrett K, Berezhkovsky L, Blair WS, Chang C, Delarosa D, DeVoss J, Driscoll J, Eigenbrot C, Goodacre S, Ghilardi N, MacLeod C, Johnson A, Bir Kohli P, Lai Y, Lin Z, Mantik P, Menghrajani K, Nguyen H, Peng I, Sambrone A, Shia S, Smith J, Sohn S, Tsui V, Ultsch M, Williams K, Wu LC, Yang W, Zhang B, Magnuson S.

Bioorg Med Chem Lett. 2017 Sep 15;27(18):4370-4376. doi: 10.1016/j.bmcl.2017.08.022. Epub 2017 Aug 12.


Consensus-derived clinical decision rules to guide advanced imaging decisions for pulmonary embolism in pregnancy and the postpartum period.

Fuller GW, Nelson-Piercy C, Hunt BJ, Lecky FE, Thomas S, Horspool K, Goodacre S.

Eur J Emerg Med. 2018 Jun;25(3):221-222. doi: 10.1097/MEJ.0000000000000477. No abstract available.


Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis.

Pickering JW, Than MP, Cullen L, Aldous S, Ter Avest E, Body R, Carlton EW, Collinson P, Dupuy AM, Ekelund U, Eggers KM, Florkowski CM, Freund Y, George P, Goodacre S, Greenslade JH, Jaffe AS, Lord SJ, Mokhtari A, Mueller C, Munro A, Mustapha S, Parsonage W, Peacock WF, Pemberton C, Richards AM, Sanchis J, Staub LP, Troughton R, Twerenbold R, Wildi K, Young J.

Ann Intern Med. 2017 May 16;166(10):715-724. doi: 10.7326/M16-2562. Epub 2017 Apr 18. Erratum in: Ann Intern Med. 2017 Oct 3;167(7):528.


Developing and assessing the acceptability of an epilepsy first aid training intervention for patients who visit UK emergency departments: A multi-method study of patients and professionals.

Snape DA, Morgan M, Ridsdale L, Goodacre S, Marson AG, Noble AJ.

Epilepsy Behav. 2017 Mar;68:177-185. doi: 10.1016/j.yebeh.2017.01.006. Epub 2017 Feb 16.


Qualitative study of paramedics' experiences of managing seizures: a national perspective from England.

Noble AJ, Snape D, Goodacre S, Jackson M, Sherratt FC, Pearson M, Marson A.

BMJ Open. 2016 Nov 9;6(11):e014022. doi: 10.1136/bmjopen-2016-014022.


AHEAD Study: an observational study of the management of anticoagulated patients who suffer head injury.

Mason S, Kuczawski M, Teare MD, Stevenson M, Goodacre S, Ramlakhan S, Morris F, Rothwell J.

BMJ Open. 2017 Jan 13;7(1):e014324. doi: 10.1136/bmjopen-2016-014324.


Paramedics' views on their seizure management learning needs: a qualitative study in England.

Sherratt FC, Snape D, Goodacre S, Jackson M, Pearson M, Marson AG, Noble AJ.

BMJ Open. 2017 Jan 9;7(1):e014024. doi: 10.1136/bmjopen-2016-014024.


Antibiotic Spider Silk: Site-Specific Functionalization of Recombinant Spider Silk Using "Click" Chemistry.

Harvey D, Bardelang P, Goodacre SL, Cockayne A, Thomas NR.

Adv Mater. 2017 Mar;29(10). doi: 10.1002/adma.201604245. Epub 2016 Dec 28.


Should all anticoagulated patients with head injury receive a CT scan? Decision-analysis modelling of an observational cohort.

Kuczawski M, Stevenson M, Goodacre S, Teare MD, Ramlakhan S, Morris F, Mason S.

BMJ Open. 2016 Dec 13;6(12):e013742. doi: 10.1136/bmjopen-2016-013742.


Can emergency medicine research benefit from adaptive design clinical trials?

Flight L, Julious SA, Goodacre S.

Emerg Med J. 2017 Apr;34(4):243-248. doi: 10.1136/emermed-2016-206046. Epub 2016 Oct 28.


High-sensitivity cardiac troponin at 3 hours: is the cat among the pigeons?

Body R, Collinson P, Goodacre S, Mills NL, Timmis A.

Heart. 2016 Aug 15;102(16):1253-4. doi: 10.1136/heartjnl-2016-309461. Epub 2016 Jun 20. No abstract available.


Patient and public involvement in emergency care research.

Hirst E, Irving A, Goodacre S.

Emerg Med J. 2016 Sep;33(9):665-70. doi: 10.1136/emermed-2016-205700. Epub 2016 Apr 4.


Effectiveness of EDACS Versus ADAPT Accelerated Diagnostic Pathways for Chest Pain: A Pragmatic Randomized Controlled Trial Embedded Within Practice.

Than MP, Pickering JW, Aldous SJ, Cullen L, Frampton CM, Peacock WF, Jaffe AS, Goodacre SW, Richards AM, Ardagh MW, Deely JM, Florkowski CM, George P, Hamilton GJ, Jardine DL, Troughton RW, van Wyk P, Young JM, Bannister L, Lord SJ.

Ann Emerg Med. 2016 Jul;68(1):93-102.e1. doi: 10.1016/j.annemergmed.2016.01.001.


The acceptability and feasibility of an anxiety reduction intervention for emergency department patients with non-cardiac chest pain.

Webster R, Thompson AR, Norman P, Goodacre S.

Psychol Health Med. 2017 Jan;22(1):1-11. Epub 2016 Feb 29.


The Recognition of STEMI by Paramedics and the Effect of Computer inTerpretation (RESPECT): a randomised crossover feasibility study.

Pilbery R, Teare MD, Goodacre S, Morris F.

Emerg Med J. 2016 Jul;33(7):471-6. doi: 10.1136/emermed-2015-204988. Epub 2016 Feb 10.


The problem of pulmonary embolism diagnosis in pregnancy.

Goodacre S, Hunt B.

Br J Haematol. 2016 Dec;175(5):971-972. doi: 10.1111/bjh.13893. Epub 2016 Jan 15. Review. No abstract available.

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