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Items: 1 to 50 of 79

1.

A Novel Transgenic Mouse Model to Investigate the Cell-Autonomous Effects of torsinA(ΔE) Expression in Striatal Output Neurons.

Gonzalez-Alegre P, Beauvais G, Martin J, Koch RJ, Walker RH, Patel JC, Rice ME, Ehrlich ME.

Neuroscience. 2019 Dec 1;422:1-11. doi: 10.1016/j.neuroscience.2019.09.007. Epub 2019 Oct 26.

PMID:
31669362
2.

Epidemiology of DYT1 dystonia: Estimating prevalence via genetic ascertainment.

Park J, Damrauer SM, Baras A, Reid JG, Overton JD, Gonzalez-Alegre P.

Neurol Genet. 2019 Sep 13;5(5):e358. doi: 10.1212/NXG.0000000000000358. eCollection 2019 Oct.

3.

Addressing the Value of Multidisciplinary Clinical Care in Huntington's Disease: A Snapshot of a New Huntington's Disease Center.

Bardakjian TM, Klapper J, Carey A, Wood J, Pauly M, Gasper K, Lawler K, Tran B, Bell Y, Zwil A, Gonzalez-Alegre P.

J Huntingtons Dis. 2019;8(4):501-507. doi: 10.3233/JHD-190355.

PMID:
31381522
4.

Human gene therapy approaches for the treatment of Parkinson's disease: An overview of current and completed clinical trials.

Hitti FL, Yang AI, Gonzalez-Alegre P, Baltuch GH.

Parkinsonism Relat Disord. 2019 Sep;66:16-24. doi: 10.1016/j.parkreldis.2019.07.018. Epub 2019 Jul 13. Review.

PMID:
31324556
5.

Recent advances in molecular therapies for neurological disease: triplet repeat disorders.

Gonzalez-Alegre P.

Hum Mol Genet. 2019 Oct 1;28(R1):R80-R87. doi: 10.1093/hmg/ddz138.

PMID:
31227833
6.

Peripheral synucleinopathy in a DJ1 patient with Parkinson disease, cataracts, and hearing loss.

Narendra DP, Isonaka R, Nguyen D, Schindler AB, Kokkinis AD, Ehrlich D, Bardakjian TM, Goldstein DS, Liang TW, Gonzalez-Alegre P.

Neurology. 2019 Jun 4;92(23):1113-1115. doi: 10.1212/WNL.0000000000007614. Epub 2019 Apr 26. No abstract available.

PMID:
31028127
7.

Advances in molecular and cell biology of dystonia: Focus on torsinA.

Gonzalez-Alegre P.

Neurobiol Dis. 2019 Jul;127:233-241. doi: 10.1016/j.nbd.2019.03.007. Epub 2019 Mar 12. Review.

PMID:
30877032
8.

Attitudes of Potential Participants Towards Molecular Therapy Trials in Huntington's Disease.

Bardakjian TM, Naczi KF, Gonzalez-Alegre P.

J Huntingtons Dis. 2019;8(1):79-85. doi: 10.3233/JHD-180328.

9.

Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene.

Maguire JA, Gagne AL, Gonzalez-Alegre P, Davidson BL, Shakkottai V, Gadue P, French DL.

Stem Cell Res. 2019 Jan;34:101361. doi: 10.1016/j.scr.2018.101361. Epub 2018 Dec 10.

10.

Efficient RNA interference-based knockdown of mutant torsinA reveals reversibility of PERK-eIF2α pathway dysregulation in DYT1 transgenic rats in vivo.

Beauvais G, Watson JL, Aguirre JA, Tecedor L, Ehrlich ME, Gonzalez-Alegre P.

Brain Res. 2019 Mar 1;1706:24-31. doi: 10.1016/j.brainres.2018.10.025. Epub 2018 Oct 23.

PMID:
30366018
11.

Hospitalizations of Children with Huntington's Disease in the United States.

Mendizabal A, Ngo Vu AT, Thibault D, Gonzalez-Alegre P, Willis A.

Mov Disord Clin Pract. 2017 Sep 11;4(5):682-688. doi: 10.1002/mdc3.12506. eCollection 2017 Sep-Oct.

12.

Gene Therapy for Neurologic Disease: A Neurosurgical Review.

Hitti FL, Gonzalez-Alegre P, Lucas TH.

World Neurosurg. 2019 Jan;121:261-273. doi: 10.1016/j.wneu.2018.09.097. Epub 2018 Sep 22. Review.

PMID:
30253990
13.

Human Immunodeficiency Virus Infection in Huntington's Disease is Associated with an Earlier Age of Symptom Onset.

Schultz JL, Nopoulos PC, Gonzalez-Alegre P.

J Huntingtons Dis. 2018;7(2):163-166. doi: 10.3233/JHD-180287.

PMID:
29843248
14.

Genetic test utilization and diagnostic yield in adult patients with neurological disorders.

Bardakjian TM, Helbig I, Quinn C, Elman LB, McCluskey LF, Scherer SS, Gonzalez-Alegre P.

Neurogenetics. 2018 May;19(2):105-110. doi: 10.1007/s10048-018-0544-x. Epub 2018 Mar 28.

PMID:
29589152
15.

Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions.

Zakirova Z, Fanutza T, Bonet J, Readhead B, Zhang W, Yi Z, Beauvais G, Zwaka TP, Ozelius LJ, Blitzer RD, Gonzalez-Alegre P, Ehrlich ME.

PLoS Genet. 2018 Jan 24;14(1):e1007169. doi: 10.1371/journal.pgen.1007169. eCollection 2018 Jan.

16.

Towards precision medicine.

Bardakjian T, Gonzalez-Alegre P.

Handb Clin Neurol. 2018;147:93-102. doi: 10.1016/B978-0-444-63233-3.00008-7. Review.

PMID:
29325630
17.

Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain.

Beauvais G, Rodriguez-Losada N, Ying L, Zakirova Z, Watson JL, Readhead B, Gadue P, French DL, Ehrlich ME, Gonzalez-Alegre P.

Neuroscience. 2018 Feb 10;371:455-468. doi: 10.1016/j.neuroscience.2017.12.033. Epub 2017 Dec 28.

PMID:
29289717
18.

THAP1: Role in Mouse Embryonic Stem Cell Survival and Differentiation.

Aguilo F, Zakirova Z, Nolan K, Wagner R, Sharma R, Hogan M, Wei C, Sun Y, Walsh MJ, Kelley K, Zhang W, Ozelius LJ, Gonzalez-Alegre P, Zwaka TP, Ehrlich ME.

Stem Cell Reports. 2017 Jul 11;9(1):92-107. doi: 10.1016/j.stemcr.2017.04.032. Epub 2017 Jun 1.

19.

Biallelic TOR1A variants in an infant with severe arthrogryposis.

Reichert SC, Gonzalez-Alegre P, Scharer GH.

Neurol Genet. 2017 May 9;3(3):e154. doi: 10.1212/NXG.0000000000000154. eCollection 2017 Jun. No abstract available.

20.

Sex-specific effects of the Huntington gene on normal neurodevelopment.

Lee JK, Ding Y, Conrad AL, Cattaneo E, Epping E, Mathews K, Gonzalez-Alegre P, Cahill L, Magnotta V, Schlaggar BL, Perlmutter JS, Kim RE, Dawson JD, Nopoulos P.

J Neurosci Res. 2017 Jan 2;95(1-2):398-408. doi: 10.1002/jnr.23980.

21.

RNAi prevents and reverses phenotypes induced by mutant human ataxin-1.

Keiser MS, Monteys AM, Corbau R, Gonzalez-Alegre P, Davidson BL.

Ann Neurol. 2016 Nov;80(5):754-765. doi: 10.1002/ana.24789. Epub 2016 Nov 2.

22.

Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.

Beauvais G, Bode NM, Watson JL, Wen H, Glenn KA, Kawano H, Harata NC, Ehrlich ME, Gonzalez-Alegre P.

J Neurosci. 2016 Oct 5;36(40):10245-10256.

23.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC Jr, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR Jr, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clària J, Clarke PG, Clarke R, Clementi E, Cleyrat C, Cnop M, Coccia EM, Cocco T, Codogno P, Coers J, Cohen EE, Colecchia D, Coletto L, Coll NS, Colucci-Guyon E, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corral-Ramos C, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Couve E, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Crespo JL, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, Dahmen U, Dai C, Dai W, Dai Y, Dalby KN, Dalla Valle L, Dalmasso G, D'Amelio M, Damme M, Darfeuille-Michaud A, Dargemont C, Darley-Usmar VM, Dasarathy S, Dasgupta B, Dash S, Dass CR, Davey HM, Davids LM, Dávila D, Davis RJ, Dawson TM, Dawson VL, Daza P, de Belleroche J, de Figueiredo P, de Figueiredo RC, de la Fuente J, De Martino L, De Matteis A, De Meyer GR, De Milito A, De Santi M, de Souza W, De Tata V, De Zio D, Debnath J, Dechant R, Decuypere JP, Deegan S, Dehay B, Del Bello B, Del Re DP, Delage-Mourroux R, Delbridge LM, Deldicque L, Delorme-Axford E, Deng Y, Dengjel J, Denizot M, Dent P, Der CJ, Deretic V, Derrien B, Deutsch E, Devarenne TP, Devenish RJ, Di Bartolomeo S, Di Daniele N, Di Domenico F, Di Nardo A, Di Paola S, Di Pietro A, Di Renzo L, DiAntonio A, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dickey CA, Dickson RC, Diederich M, Digard P, Dikic I, Dinesh-Kumar SP, Ding C, Ding WX, Ding Z, Dini L, Distler JH, Diwan A, Djavaheri-Mergny M, Dmytruk K, Dobson RC, Doetsch V, Dokladny K, Dokudovskaya S, Donadelli M, Dong XC, Dong X, Dong Z, Donohue TM Jr, Doran KS, D'Orazi G, Dorn GW 2nd, Dosenko V, Dridi S, Drucker L, Du J, Du LL, Du L, du Toit A, Dua P, Duan L, Duann P, Dubey VK, Duchen MR, Duchosal MA, Duez H, Dugail I, Dumit VI, Duncan MC, Dunlop EA, Dunn WA Jr, Dupont N, Dupuis L, Durán RV, Durcan TM, Duvezin-Caubet S, Duvvuri U, Eapen V, Ebrahimi-Fakhari D, Echard A, Eckhart L, Edelstein CL, Edinger AL, Eichinger L, Eisenberg T, Eisenberg-Lerner A, Eissa NT, El-Deiry WS, El-Khoury V, Elazar Z, Eldar-Finkelman H, Elliott CJ, Emanuele E, Emmenegger U, Engedal N, Engelbrecht AM, Engelender S, Enserink JM, Erdmann R, Erenpreisa J, Eri R, Eriksen JL, Erman A, Escalante R, Eskelinen EL, Espert L, Esteban-Martínez L, Evans TJ, Fabri M, Fabrias G, Fabrizi C, Facchiano A, Færgeman NJ, Faggioni A, Fairlie WD, Fan C, Fan D, Fan J, Fang S, Fanto M, Fanzani A, Farkas T, Faure M, Favier FB, Fearnhead H, Federici M, Fei E, Felizardo TC, Feng H, Feng Y, Feng Y, Ferguson TA, Fernández ÁF, Fernandez-Barrena MG, Fernandez-Checa JC, Fernández-López A, Fernandez-Zapico ME, Feron O, Ferraro E, Ferreira-Halder CV, Fesus L, Feuer R, Fiesel FC, Filippi-Chiela EC, Filomeni G, Fimia GM, Fingert JH, Finkbeiner S, Finkel T, Fiorito F, Fisher PB, Flajolet M, Flamigni F, Florey O, Florio S, Floto RA, Folini M, Follo C, Fon EA, Fornai F, Fortunato F, Fraldi A, Franco R, Francois A, François A, Frankel LB, Fraser ID, Frey N, Freyssenet DG, Frezza C, Friedman SL, Frigo DE, Fu D, Fuentes JM, Fueyo J, Fujitani Y, Fujiwara Y, Fujiya M, Fukuda M, Fulda S, Fusco C, Gabryel B, Gaestel M, Gailly P, Gajewska M, Galadari S, Galili G, Galindo I, Galindo MF, Galliciotti G, Galluzzi L, Galluzzi L, Galy V, Gammoh N, Gandy S, Ganesan AK, Ganesan S, Ganley IG, Gannagé M, Gao FB, Gao F, Gao JX, García Nannig L, García Véscovi E, Garcia-Macía M, Garcia-Ruiz C, Garg AD, Garg PK, Gargini R, Gassen NC, Gatica D, Gatti E, Gavard J, Gavathiotis E, Ge L, Ge P, Ge S, Gean PW, Gelmetti V, Genazzani AA, Geng J, Genschik P, Gerner L, Gestwicki JE, Gewirtz DA, Ghavami S, Ghigo E, Ghosh D, Giammarioli AM, Giampieri F, Giampietri C, Giatromanolaki A, Gibbings DJ, Gibellini L, Gibson SB, Ginet V, Giordano A, Giorgini F, Giovannetti E, Girardin SE, Gispert S, Giuliano S, Gladson CL, Glavic A, Gleave M, Godefroy N, Gogal RM Jr, Gokulan K, Goldman GH, Goletti D, Goligorsky MS, Gomes AV, Gomes LC, Gomez H, Gomez-Manzano C, Gómez-Sánchez R, Gonçalves DA, Goncu E, Gong Q, Gongora C, Gonzalez CB, Gonzalez-Alegre P, Gonzalez-Cabo P, González-Polo RA, Goping IS, Gorbea C, Gorbunov NV, Goring DR, Gorman AM, Gorski SM, Goruppi S, Goto-Yamada S, Gotor C, Gottlieb RA, Gozes I, Gozuacik D, Graba Y, Graef M, Granato GE, Grant GD, Grant S, Gravina GL, Green DR, Greenhough A, Greenwood MT, Grimaldi B, Gros F, Grose C, Groulx JF, Gruber F, Grumati P, Grune T, Guan JL, Guan KL, Guerra B, Guillen C, Gulshan K, Gunst J, Guo C, Guo L, Guo M, Guo W, Guo XG, Gust AA, Gustafsson ÅB, Gutierrez E, Gutierrez MG, Gwak HS, Haas A, Haber JE, Hadano S, Hagedorn M, Hahn DR, Halayko AJ, Hamacher-Brady A, Hamada K, Hamai A, Hamann A, Hamasaki M, Hamer I, Hamid Q, Hammond EM, Han F, Han W, Handa JT, Hanover JA, Hansen M, Harada M, Harhaji-Trajkovic L, Harper JW, Harrath AH, Harris AL, Harris J, Hasler U, Hasselblatt P, Hasui K, Hawley RG, Hawley TS, He C, He CY, He F, He G, He RR, He XH, He YW, He YY, Heath JK, Hébert MJ, Heinzen RA, Helgason GV, Hensel M, Henske EP, Her C, Herman PK, Hernández A, Hernandez C, Hernández-Tiedra S, Hetz C, Hiesinger PR, Higaki K, Hilfiker S, Hill BG, Hill JA, Hill WD, Hino K, Hofius D, Hofman P, Höglinger GU, Höhfeld J, Holz MK, Hong Y, Hood DA, Hoozemans JJ, Hoppe T, Hsu C, Hsu CY, Hsu LC, Hu D, Hu G, Hu HM, Hu H, Hu MC, Hu YC, Hu ZW, Hua F, Hua Y, Huang C, Huang HL, Huang KH, Huang KY, Huang S, Huang S, Huang WP, Huang YR, Huang Y, Huang Y, Huber TB, Huebbe P, Huh WK, Hulmi JJ, Hur GM, Hurley JH, Husak Z, Hussain SN, Hussain S, Hwang JJ, Hwang S, Hwang TI, Ichihara A, Imai Y, Imbriano C, Inomata M, Into T, Iovane V, Iovanna JL, Iozzo RV, Ip NY, Irazoqui JE, Iribarren P, Isaka Y, Isakovic AJ, Ischiropoulos H, Isenberg JS, Ishaq M, Ishida H, Ishii I, Ishmael JE, Isidoro C, Isobe K, Isono E, Issazadeh-Navikas S, Itahana K, Itakura E, Ivanov AI, Iyer AK, Izquierdo JM, Izumi Y, Izzo V, Jäättelä M, Jaber N, Jackson DJ, Jackson WT, Jacob TG, Jacques TS, Jagannath C, Jain A, Jana NR, Jang BK, Jani A, Janji B, Jannig PR, Jansson PJ, Jean S, Jendrach M, Jeon JH, Jessen N, Jeung EB, Jia K, Jia L, Jiang H, Jiang H, Jiang L, Jiang T, Jiang X, Jiang X, Jiang X, Jiang Y, Jiang Y, Jiménez A, Jin C, Jin H, Jin L, Jin M, Jin S, Jinwal UK, Jo EK, Johansen T, Johnson DE, Johnson GV, Johnson JD, Jonasch E, Jones C, Joosten LA, Jordan J, Joseph AM, Joseph B, Joubert AM, Ju D, Ju J, Juan HF, Juenemann K, Juhász G, Jung HS, Jung JU, Jung YK, Jungbluth H, Justice MJ, Jutten B, Kaakoush NO, Kaarniranta K, Kaasik A, Kabuta T, Kaeffer B, Kågedal K, Kahana A, Kajimura S, Kakhlon O, Kalia M, Kalvakolanu DV, Kamada Y, Kambas K, Kaminskyy VO, Kampinga HH, Kandouz M, Kang C, Kang R, Kang TC, Kanki T, Kanneganti TD, Kanno H, Kanthasamy AG, Kantorow M, Kaparakis-Liaskos M, Kapuy O, Karantza V, Karim MR, Karmakar P, Kaser A, Kaushik S, Kawula T, Kaynar AM, Ke PY, Ke ZJ, Kehrl JH, Keller KE, Kemper JK, Kenworthy AK, Kepp O, Kern A, Kesari S, Kessel D, Ketteler R, Kettelhut Ido C, Khambu B, Khan MM, Khandelwal VK, Khare S, Kiang JG, Kiger AA, Kihara A, Kim AL, Kim CH, Kim DR, Kim DH, Kim EK, Kim HY, Kim HR, Kim JS, Kim JH, Kim JC, Kim JH, Kim KW, Kim MD, Kim MM, Kim PK, Kim SW, Kim SY, Kim YS, Kim Y, Kimchi A, Kimmelman AC, Kimura T, King JS, Kirkegaard K, Kirkin V, Kirshenbaum LA, Kishi S, Kitajima Y, Kitamoto K, Kitaoka Y, Kitazato K, Kley RA, Klimecki WT, Klinkenberg M, Klucken J, Knævelsrud H, Knecht E, Knuppertz L, Ko JL, Kobayashi S, Koch JC, Koechlin-Ramonatxo C, Koenig U, Koh YH, Köhler K, Kohlwein SD, Koike M, Komatsu M, Kominami E, Kong D, Kong HJ, Konstantakou EG, Kopp BT, Korcsmaros T, Korhonen L, Korolchuk VI, Koshkina NV, Kou Y, Koukourakis MI, Koumenis C, Kovács AL, Kovács T, Kovacs WJ, Koya D, Kraft C, Krainc D, Kramer H, Kravic-Stevovic T, Krek W, Kretz-Remy C, Krick R, Krishnamurthy M, Kriston-Vizi J, Kroemer G, Kruer MC, Kruger R, Ktistakis NT, Kuchitsu K, Kuhn C, Kumar AP, Kumar A, Kumar A, Kumar D, Kumar D, Kumar R, Kumar S, Kundu M, Kung HJ, Kuno A, Kuo SH, Kuret J, Kurz T, Kwok T, Kwon TK, Kwon YT, Kyrmizi I, La Spada AR, Lafont F, Lahm T, Lakkaraju A, Lam T, Lamark T, Lancel S, Landowski TH, Lane DJ, Lane JD, Lanzi C, Lapaquette P, Lapierre LR, Laporte J, Laukkarinen J, Laurie GW, Lavandero S, Lavie L, LaVoie MJ, Law BY, Law HK, Law KB, Layfield R, Lazo PA, Le Cam L, Le Roch KG, Le Stunff H, Leardkamolkarn V, Lecuit M, Lee BH, Lee CH, Lee EF, Lee GM, Lee HJ, Lee H, Lee JK, Lee J, Lee JH, Lee JH, Lee M, Lee MS, Lee PJ, Lee SW, Lee SJ, Lee SJ, Lee SY, Lee SH, Lee SS, Lee SJ, Lee S, Lee YR, Lee YJ, Lee YH, Leeuwenburgh C, Lefort S, Legouis R, Lei J, Lei QY, Leib DA, Leibowitz G, Lekli I, Lemaire SD, Lemasters JJ, Lemberg MK, Lemoine A, Leng S, Lenz G, Lenzi P, Lerman LO, Lettieri Barbato D, Leu JI, Leung HY, Levine B, Lewis PA, Lezoualc'h F, Li C, Li F, Li FJ, Li J, Li K, Li L, 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JT, Yu J, Yu L, Yu WH, Yu XF, Yu Z, Yuan J, Yuan ZM, Yue BY, Yue J, Yue Z, Zacks DN, Zacksenhaus E, Zaffaroni N, Zaglia T, Zakeri Z, Zecchini V, Zeng J, Zeng M, Zeng Q, Zervos AS, Zhang DD, Zhang F, Zhang G, Zhang GC, Zhang H, Zhang H, Zhang H, Zhang H, Zhang J, Zhang J, Zhang J, Zhang J, Zhang JP, Zhang L, Zhang L, Zhang L, Zhang L, Zhang MY, Zhang X, Zhang XD, Zhang Y, Zhang Y, Zhang Y, Zhang Y, Zhang Y, Zhao M, Zhao WL, Zhao X, Zhao YG, Zhao Y, Zhao Y, Zhao YX, Zhao Z, Zhao ZJ, Zheng D, Zheng XL, Zheng X, Zhivotovsky B, Zhong Q, Zhou GZ, Zhou G, Zhou H, Zhou SF, Zhou XJ, Zhu H, Zhu H, Zhu WG, Zhu W, Zhu XF, Zhu Y, Zhuang SM, Zhuang X, Ziparo E, Zois CE, Zoladek T, Zong WX, Zorzano A, Zughaier SM.

Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. No abstract available. Erratum in: Autophagy. 2016;12(2):443. Selliez, Iban [corrected to Seiliez, Iban].

24.

Alzheimer's like brain changes correlate with low adiponectin plasma levels in type 2 diabetic patients.

García-Casares N, García-Arnés JA, Rioja J, Ariza MJ, Gutiérrez A, Alfaro F, Nabrozidis A, González-Alegre P, González-Santos P.

J Diabetes Complications. 2016 Mar;30(2):281-6. doi: 10.1016/j.jdiacomp.2015.12.001. Epub 2015 Dec 11.

PMID:
26796431
25.

Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy.

Keiser MS, Kordower JH, Gonzalez-Alegre P, Davidson BL.

Brain. 2015 Dec;138(Pt 12):3555-66. doi: 10.1093/brain/awv292. Epub 2015 Oct 21.

26.

Abnormal Weight and Body Mass Index in Children with Juvenile Huntington's Disease.

Tereshchenko A, McHugh M, Lee JK, Gonzalez-Alegre P, Crane K, Dawson J, Nopoulos P.

J Huntingtons Dis. 2015;4(3):231-238. doi: 10.3233/JHD-150152.

27.

Abnormalities of motor function, transcription and cerebellar structure in mouse models of THAP1 dystonia.

Ruiz M, Perez-Garcia G, Ortiz-Virumbrales M, Méneret A, Morant A, Kottwitz J, Fuchs T, Bonet J, Gonzalez-Alegre P, Hof PR, Ozelius LJ, Ehrlich ME.

Hum Mol Genet. 2015 Dec 20;24(25):7159-70. doi: 10.1093/hmg/ddv384. Epub 2015 Sep 16.

28.

Residency training: a failed lumbar puncture is more about obesity than lack of ability.

Edwards C, Leira EC, Gonzalez-Alegre P.

Neurology. 2015 Mar 10;84(10):e69-72. doi: 10.1212/WNL.0000000000001335.

PMID:
25754807
29.

Evaluating Familial Essential Tremor with Novel Genetic Approaches: Is it a Genotyping or Phenotyping Issue?

Gonzalez-Alegre P, Di Paola J, Wang K, Fabbro S, Yu HC, Shaikh TH, Darbro BW, Bassuk AG.

Tremor Other Hyperkinet Mov (N Y). 2014 Oct 20;4:258. doi: 10.7916/D8FB51G3. eCollection 2014.

30.

Cognitive dysfunctions in middle-aged type 2 diabetic patients and neuroimaging correlations: a cross-sectional study.

García-Casares N, Jorge RE, García-Arnés JA, Acion L, Berthier ML, Gonzalez-Alegre P, Nabrozidis A, Gutiérrez A, Ariza MJ, Rioja J, González-Santos P.

J Alzheimers Dis. 2014;42(4):1337-46. doi: 10.3233/JAD-140702.

PMID:
25024335
31.

Clinical, Etiological, and Therapeutic Features of Jaw-opening and Jaw-closing Oromandibular Dystonias: A Decade of Experience at a Single Treatment Center.

Gonzalez-Alegre P, Schneider RL, Hoffman H.

Tremor Other Hyperkinet Mov (N Y). 2014 Apr 30;4:231. doi: 10.7916/D8TH8JSM. eCollection 2014.

32.

Structural and functional brain changes in middle-aged type 2 diabetic patients: a cross-sectional study.

García-Casares N, Berthier ML, Jorge RE, Gonzalez-Alegre P, Gutiérrez Cardo A, Rioja Villodres J, Acion L, Ariza Corbo MJ, Nabrozidis A, García-Arnés JA, González-Santos P.

J Alzheimers Dis. 2014;40(2):375-86. doi: 10.3233/JAD-131736.

33.

PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders.

Paemka L, Mahajan VB, Skeie JM, Sowers LP, Ehaideb SN, Gonzalez-Alegre P, Sasaoka T, Tao H, Miyagi A, Ueno N, Takao K, Miyakawa T, Wu S, Darbro BW, Ferguson PJ, Pieper AA, Britt JK, Wemmie JA, Rudd DS, Wassink T, El-Shanti H, Mefford HC, Carvill GL, Manak JR, Bassuk AG.

PLoS One. 2013 Dec 3;8(12):e80737. doi: 10.1371/journal.pone.0080737. eCollection 2013.

34.

Two cases of pregnancy in Parkinson's disease.

Lamichhane D, Narayanan NS, Gonzalez-Alegre P.

Parkinsonism Relat Disord. 2014 Feb;20(2):239-40. doi: 10.1016/j.parkreldis.2013.10.013. Epub 2013 Oct 20. No abstract available.

35.

A novel mutation in PLP1 causes severe hereditary spastic paraplegia type 2.

Noetzli L, Sanz PG, Brodsky GL, Hinckley JD, Giugni JC, Giannaula RJ, Gonzalez-Alegre P, Di Paola J.

Gene. 2014 Jan 1;533(1):447-50. doi: 10.1016/j.gene.2013.09.076. Epub 2013 Oct 5.

PMID:
24103481
36.

Exploring the link between dystonia genes and idiopathic scoliosis.

Gonzalez-Alegre P, Buffard V, Wang K, Henien S, Morcuende JA.

J Pediatr Orthop. 2013 Sep;33(6):e65-6. doi: 10.1097/BPO.0b013e31829aac15.

PMID:
23812140
37.

Huntington's disease in children.

Letort D, Gonzalez-Alegre P.

Handb Clin Neurol. 2013;113:1913-7. doi: 10.1016/B978-0-444-59565-2.00061-7. Review.

PMID:
23622414
38.

The ubiquitin ligase F-box/G-domain protein 1 promotes the degradation of the disease-linked protein torsinA through the ubiquitin-proteasome pathway and macroautophagy.

Gordon KL, Glenn KA, Bode N, Wen HM, Paulson HL, Gonzalez-Alegre P.

Neuroscience. 2012 Nov 8;224:160-71. doi: 10.1016/j.neuroscience.2012.08.023. Epub 2012 Aug 20.

39.

DYT1 knock-in mice are not sensitized against mitochondrial complex-II inhibition.

Bode N, Massey C, Gonzalez-Alegre P.

PLoS One. 2012;7(8):e42644. doi: 10.1371/journal.pone.0042644. Epub 2012 Aug 3.

40.

Clinical predictors of driving status in Huntington's disease.

Beglinger LJ, Prest L, Mills JA, Paulsen JS, Smith MM, Gonzalez-Alegre P, Rowe KC, Nopoulos P, Uc EY.

Mov Disord. 2012 Aug;27(9):1146-52. doi: 10.1002/mds.25101. Epub 2012 Jun 28.

41.

Miniature release events of glutamate from hippocampal neurons are influenced by the dystonia-associated protein torsinA.

Kakazu Y, Koh JY, Iwabuchi S, Gonzalez-Alegre P, Harata NC.

Synapse. 2012 Sep;66(9):807-22. doi: 10.1002/syn.21571. Epub 2012 Jun 20.

PMID:
22588999
42.

Substance abuse may be a risk factor for earlier onset of Huntington disease.

Byars JA, Beglinger LJ, Moser DJ, Gonzalez-Alegre P, Nopoulos P.

J Neurol. 2012 Sep;259(9):1824-31. doi: 10.1007/s00415-012-6415-8. Epub 2012 Jan 25.

PMID:
22274789
43.

Synaptic vesicle recycling is enhanced by torsinA that harbors the DYT1 dystonia mutation.

Kakazu Y, Koh JY, Ho KW, Gonzalez-Alegre P, Harata NC.

Synapse. 2012 May;66(5):453-64. doi: 10.1002/syn.21534. Epub 2012 Feb 15.

PMID:
22213465
44.

Secondary dystonia in a botulinum toxin clinic: clinical characteristics, neuroanatomical substrate and comparison with idiopathic dystonia.

Strader S, Rodnitzky RL, Gonzalez-Alegre P.

Parkinsonism Relat Disord. 2011 Dec;17(10):749-52. doi: 10.1016/j.parkreldis.2011.07.013. Epub 2011 Aug 17.

PMID:
21852177
45.

A functional role for TorsinA in herpes simplex virus 1 nuclear egress.

Maric M, Shao J, Ryan RJ, Wong CS, Gonzalez-Alegre P, Roller RJ.

J Virol. 2011 Oct;85(19):9667-79. doi: 10.1128/JVI.05314-11. Epub 2011 Jul 20.

46.

Lethal toxicity caused by expression of shRNA in the mouse striatum: implications for therapeutic design.

Martin JN, Wolken N, Brown T, Dauer WT, Ehrlich ME, Gonzalez-Alegre P.

Gene Ther. 2011 Jul;18(7):666-73. doi: 10.1038/gt.2011.10. Epub 2011 Mar 3.

47.

Exploring the influence of torsinA expression on protein quality control.

Gordon KL, Glenn KA, Gonzalez-Alegre P.

Neurochem Res. 2011 Mar;36(3):452-9. doi: 10.1007/s11064-010-0363-4. Epub 2010 Dec 16.

PMID:
21161590
48.

FBG1 is a promiscuous ubiquitin ligase that sequesters APC2 and causes S-phase arrest.

Wen H, Kim N, Fuentes EJ, Mallinger A, Gonzalez-Alegre P, Glenn KA.

Cell Cycle. 2010 Nov 15;9(22):4506-17.

49.

Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties.

Harris GM, Dodelzon K, Gong L, Gonzalez-Alegre P, Paulson HL.

PLoS One. 2010 Oct 27;5(10):e13695. doi: 10.1371/journal.pone.0013695.

50.

Cell-autonomous alteration of dopaminergic transmission by wild type and mutant (DeltaE) TorsinA in transgenic mice.

Page ME, Bao L, Andre P, Pelta-Heller J, Sluzas E, Gonzalez-Alegre P, Bogush A, Khan LE, Iacovitti L, Rice ME, Ehrlich ME.

Neurobiol Dis. 2010 Sep;39(3):318-26. doi: 10.1016/j.nbd.2010.04.016. Epub 2010 May 10.

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