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Items: 1 to 50 of 1224

1.

The olive constituent oleuropein, as a PPARα agonist, markedly reduces serum triglycerides.

Malliou F, Andreadou I, Gonzalez FJ, Lazou A, Xepapadaki E, Vallianou I, Lambrinidis G, Mikros E, Marselos M, Skaltsounis AL, Konstandi M.

J Nutr Biochem. 2018 Jun 5;59:17-28. doi: 10.1016/j.jnutbio.2018.05.013. [Epub ahead of print]

PMID:
29960113
2.

Glycyrrhizin alleviates non-alcoholic steatohepatitis via modulating bile acids and meta-inflammation.

Yan T, Wang H, Cao L, Wang Q, Takahashi S, Yagai T, Li G, Krausz KW, Wang G, Gonzalez FJ, Hao H.

Drug Metab Dispos. 2018 Jun 29. pii: dmd.118.082008. doi: 10.1124/dmd.118.082008. [Epub ahead of print]

PMID:
29959134
3.

Activation of aryl hydrocarbon receptor regulates the LPS/IFNγ-induced inflammatory response by inducing ubiquitin-proteosomal and lysosomal degradation of RelA/p65.

Domínguez-Acosta O, Vega L, Estrada-Muñiz E, Rodríguez MS, Gonzalez FJ, Elizondo G.

Biochem Pharmacol. 2018 Jun 21;155:141-149. doi: 10.1016/j.bcp.2018.06.016. [Epub ahead of print]

PMID:
29935959
4.

In vitrometabolic mapping of neobavaisoflavone in human cytochromes P450 and UDP-glucuronosyltransferase enzymes by ultra high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry.

Xu J, Li M, Yao Z, Zhang Y, Li S, Hu L, Qin Z, Gonzalez FJ, Yao X.

J Pharm Biomed Anal. 2018 Jun 18;158:351-360. doi: 10.1016/j.jpba.2018.06.022. [Epub ahead of print]

PMID:
29933228
5.

A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice.

Wang YK, Yang XN, Liang WQ, Xiao Y, Zhao Q, Xiao XR, Gonzalez FJ, Li F.

Xenobiotica. 2018 Jun 13:1-53. doi: 10.1080/00498254.2018.1489167. [Epub ahead of print]

PMID:
29897827
6.

Metabolic alterations in triptolide-induced acute hepatotoxicity.

Zhao J, Xie C, Mu X, Krausz KW, Patel DP, Shi X, Gao X, Wang Q, Gonzalez FJ.

Biomed Chromatogr. 2018 May 25:e4299. doi: 10.1002/bmc.4299. [Epub ahead of print]

PMID:
29799631
7.

Detection of hydroquinone by Raman spectroscopy in patients with melasma before and after treatment.

Cabrera-Alonso R, Guevara E, Ramírez-Elías MG, Moncada B, González FJ.

Skin Res Technol. 2018 May 23. doi: 10.1111/srt.12589. [Epub ahead of print]

PMID:
29790609
8.

A Home-Made Trap Baited With Sex Pheromone for Monitoring Spodoptera Frugiperda Males (Lepidoptera: Noctuidae) in Corn crops in Mexico.

Malo EA, Cruz-Esteban S, González FJ, Rojas JC.

J Econ Entomol. 2018 May 15. doi: 10.1093/jee/toy128. [Epub ahead of print]

PMID:
29771331
9.

Lipidomics reveal Aryl hydrocarbon receptor (Ahr)-regulated lipid metabolic pathway in alpha-naphthyl isothiocyanate(ANIT)-induced intrahepatic cholestasis.

Wang BL, Zhang CW, Wang L, Tang KL, Tanaka N, Gonzalez FJ, Xu Y, Fang ZZ.

Xenobiotica. 2018 May 8:1-33. doi: 10.1080/00498254.2018.1467065. [Epub ahead of print]

PMID:
29737914
10.

Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance.

Zhang SY, Dong YQ, Wang P, Zhang X, Yan Y, Sun L, Liu B, Zhang D, Zhang H, Liu H, Kong W, Hu G, Shah YM, Gonzalez FJ, Wang X, Jiang C.

EBioMedicine. 2018 May;31:202-216. doi: 10.1016/j.ebiom.2018.04.022. Epub 2018 Apr 27.

11.

Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells.

Borland MG, Kehres EM, Lee C, Wagner AL, Shannon BE, Albrecht PP, Zhu B, Gonzalez FJ, Peters JM.

Toxicology. 2018 Jul 1;404-405:25-32. doi: 10.1016/j.tox.2018.05.003. Epub 2018 May 3.

PMID:
29729928
12.

Inverse association of vitamin D3 levels with lung cancer mediated by genetic variation.

Haznadar M, Krausz KW, Margono E, Diehl CM, Bowman ED, Manna SK, Robles AI, Ryan BM, Gonzalez FJ, Harris CC.

Cancer Med. 2018 Jun;7(6):2764-2775. doi: 10.1002/cam4.1444. Epub 2018 May 3.

13.

Structure-Activity Relationships of the Main Bioactive Constituents of Euodia rutaecarpa on Aryl Hydrocarbon Receptor Activation and Associated Bile Acid Homeostasis.

Zhang Y, Yan T, Sun D, Xie C, Zheng Y, Zhang L, Yagai T, Krausz KW, Bisson WH, Yang X, Gonzalez FJ.

Drug Metab Dispos. 2018 Jul;46(7):1030-1040. doi: 10.1124/dmd.117.080176. Epub 2018 Apr 24. Erratum in: Drug Metab Dispos. 2018 Aug;46(8):1190.

14.

PPARα Mediates the Hepatoprotective Effects of Nutmeg.

Yang XN, Liu XM, Fang JH, Zhu X, Yang XW, Xiao XR, Huang JF, Gonzalez FJ, Li F.

J Proteome Res. 2018 May 4;17(5):1887-1897. doi: 10.1021/acs.jproteome.7b00901. Epub 2018 Apr 25.

PMID:
29664296
15.

Metabolic profiling of corylin in vivo and in vitro.

Qin Z, Li S, Yao Z, Hong X, Xu J, Lin P, Zhao G, Gonzalez FJ, Yao X.

J Pharm Biomed Anal. 2018 Jun 5;155:157-168. doi: 10.1016/j.jpba.2018.03.047. Epub 2018 Mar 26.

PMID:
29631076
16.

Left Single Lung Transplantation Through Left Anterolateral Thoracotomy With Longitudinal Partial Sternotomy (Hemiclamshell): An Innovative Surgical Resource.

Murillo DA, Cerezo F, Gauman HD, Gonzalez FJ, Muñoz A, Moreno PM, Ceballos MJ, Salvatierra A.

Transplant Proc. 2018 Mar;50(2):661-663. doi: 10.1016/j.transproceed.2017.09.049.

PMID:
29579882
17.

Targeted Metabolomics Reveals a Protective Role for Basal PPARα in Cholestasis Induced by α-Naphthylisothiocyanate.

Dai M, Hua H, Lin H, Xu G, Hu X, Li F, Gonzalez FJ, Liu A, Yang J.

J Proteome Res. 2018 Apr 6;17(4):1500-1508. doi: 10.1021/acs.jproteome.7b00838. Epub 2018 Mar 7.

PMID:
29498526
18.

Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism.

Pathak P, Xie C, Nichols RG, Ferrell JM, Boehme S, Krausz KW, Patterson AD, Gonzalez FJ, Chiang JYL.

Hepatology. 2018 Feb 27. doi: 10.1002/hep.29857. [Epub ahead of print]

PMID:
29486523
19.

Fat-specific protein 27 is a novel target gene of liver X receptor α.

Aibara D, Matsusue K, Takiguchi S, Gonzalez FJ, Yamano S.

Mol Cell Endocrinol. 2018 Feb 15. pii: S0303-7207(18)30066-2. doi: 10.1016/j.mce.2018.02.006. [Epub ahead of print]

PMID:
29454584
20.

Role of the pregnane X receptor in binge ethanol-induced steatosis and hepatotoxicity.

Choi S, Gyamfi AA, Neequaye P, Addo S, Gonzalez FJ, Gyamfi MA.

J Pharmacol Exp Ther. 2018 Feb 5. pii: jpet.117.244665. doi: 10.1124/jpet.117.244665. [Epub ahead of print]

21.

Corrigendum to "Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha" [Mol Metab 7 (2018) 80-89].

Li G, Brocker CN, Yan T, Xie C, Krausz KW, Xiang R, Gonzalez FJ.

Mol Metab. 2018 Mar;9:217-219. doi: 10.1016/j.molmet.2018.01.008. Epub 2018 Feb 2. No abstract available.

22.

Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2α Inhibitor PT2385 In Vivo and In Vitro.

Xie C, Gao X, Sun D, Zhang Y, Krausz KW, Qin X, Gonzalez FJ.

Drug Metab Dispos. 2018 Apr;46(4):336-345. doi: 10.1124/dmd.117.079723. Epub 2018 Jan 23.

23.

Effects of disease salience and xenophobia on support for humanitarian aid.

Peterson JC, Gonzalez FJ, Schneider SP.

Politics Life Sci. 2017 Fall;36(2):17-36. doi: 10.1017/pls.2017.24.

PMID:
29355100
24.

The Edge is a Horizon: Commentary on Hansbury.

González FJ.

J Am Psychoanal Assoc. 2017 Dec;65(6):1061-1073. doi: 10.1177/0003065117751136. No abstract available.

PMID:
29327627
26.

Carnitine palmitoyltransferase 1C regulates cancer cell senescence through mitochondria-associated metabolic reprograming.

Wang Y, Chen Y, Guan L, Zhang H, Huang Y, Johnson CH, Wu Z, Gonzalez FJ, Yu A, Huang P, Wang Y, Yang S, Chen P, Fan X, Huang M, Bi H.

Cell Death Differ. 2018 Mar;25(4):733-746. doi: 10.1038/s41418-017-0013-3. Epub 2018 Jan 9.

PMID:
29317762
27.

Pharmacophore-based virtual screening of catechol-o-methyltransferase (COMT) inhibitors to combat Alzheimer's disease.

Patel CN, Georrge JJ, Modi KM, Narechania MB, Patel DP, Gonzalez FJ, Pandya HA.

J Biomol Struct Dyn. 2017 Dec 27:1-20. doi: 10.1080/07391102.2017.1404931. [Epub ahead of print]

PMID:
29281938
28.

Simultaneous determination of etonogestrel and ethinyl estradiol in human plasma by UPLC-MS/MS and its pharmacokinetic study.

Nair SG, Patel DP, Gonzalez FJ, Patel BM, Singhal P, Chaudhary DV.

Biomed Chromatogr. 2018 May;32(5):e4165. doi: 10.1002/bmc.4165. Epub 2018 Jan 19.

PMID:
29228469
29.

Hepatic Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) regulates metabolism in mice.

Scott CH, Cha KM, Ngai J, Jiang C, Cheng K, Stokes RA, Ho KWK, George J, Gonzalez FJ, Gunton JE.

PLoS One. 2017 Nov 30;12(11):e0186543. doi: 10.1371/journal.pone.0186543. eCollection 2017.

30.

Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha.

Li G, Brocker CN, Yan T, Xie C, Krausz KW, Xiang R, Gonzalez FJ.

Mol Metab. 2018 Jan;7:80-89. doi: 10.1016/j.molmet.2017.10.011. Epub 2017 Nov 6. Erratum in: Mol Metab. 2018 Jan 23;:.

31.

Morphological changes in erythrocytes of people with type 2 diabetes mellitus evaluated with atomic force microscopy: A brief review.

Loyola-Leyva A, Loyola-Rodríguez JP, Atzori M, González FJ.

Micron. 2018 Feb;105:11-17. doi: 10.1016/j.micron.2017.11.001. Epub 2017 Nov 10. Review.

PMID:
29145008
32.

Hepatic peroxisome proliferator-activated receptor alpha mediates the major metabolic effects of Wy-14643.

Li G, Brocker CN, Xie C, Yan T, Noguchi A, Krausz KW, Xiang R, Gonzalez FJ.

J Gastroenterol Hepatol. 2018 May;33(5):1138-1145. doi: 10.1111/jgh.14046. Epub 2018 Feb 19.

PMID:
29141109
33.

Pregnane X receptor promotes ethanol-induced hepatosteatosis in mice.

Choi S, Neequaye P, French SW, Gonzalez FJ, Gyamfi MA.

J Biol Chem. 2018 Jan 5;293(1):1-17. doi: 10.1074/jbc.M117.815217. Epub 2017 Nov 9.

PMID:
29123032
34.

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.

Li G, Xie C, Lu S, Nichols RG, Tian Y, Li L, Patel D, Ma Y, Brocker CN, Yan T, Krausz KW, Xiang R, Gavrilova O, Patterson AD, Gonzalez FJ.

Cell Metab. 2017 Nov 7;26(5):801. doi: 10.1016/j.cmet.2017.10.007. No abstract available.

35.

FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.

Wang XX, Wang D, Luo Y, Myakala K, Dobrinskikh E, Rosenberg AZ, Levi J, Kopp JB, Field A, Hill A, Lucia S, Qiu L, Jiang T, Peng Y, Orlicky D, Garcia G, Herman-Edelstein M, D'Agati V, Henriksen K, Adorini L, Pruzanski M, Xie C, Krausz KW, Gonzalez FJ, Ranjit S, Dvornikov A, Gratton E, Levi M.

J Am Soc Nephrol. 2018 Jan;29(1):118-137. doi: 10.1681/ASN.2017020222. Epub 2017 Oct 31.

PMID:
29089371
36.

Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis.

Xie C, Yagai T, Luo Y, Liang X, Chen T, Wang Q, Sun D, Zhao J, Ramakrishnan SK, Sun L, Jiang C, Xue X, Tian Y, Krausz KW, Patterson AD, Shah YM, Wu Y, Jiang C, Gonzalez FJ.

Nat Med. 2017 Nov;23(11):1298-1308. doi: 10.1038/nm.4412. Epub 2017 Oct 9.

PMID:
29035368
37.

Editor's Highlight: PPARβ/δ and PPARγ Inhibit Melanoma Tumorigenicity by Modulating Inflammation and Apoptosis.

Borland MG, Yao PL, Kehres EM, Lee C, Pritzlaff AM, Ola E, Wagner AL, Shannon BE, Albrecht PP, Zhu B, Kang BH, Robertson GP, Gonzalez FJ, Peters JM.

Toxicol Sci. 2017 Oct 1;159(2):436-448. doi: 10.1093/toxsci/kfx147.

PMID:
28962521
38.

Distinct role of nuclear receptor corepressor 1 regulated de novo fatty acids synthesis in liver regeneration and hepatocarcinogenesis in mice.

Ou-Yang Q, Lin XM, Zhu YJ, Zheng B, Li L, Yang YC, Hou GJ, Chen X, Luo GJ, Huo F, Leng QB, Gonzalez FJ, Jiang XQ, Wang HY, Chen L.

Hepatology. 2018 Mar;67(3):1071-1087. doi: 10.1002/hep.29562. Epub 2018 Jan 26.

PMID:
28960380
39.

ISN Forefronts Symposium 2015: Nuclear Receptors and Diabetic Nephropathy.

Zheng B, Chen L, Gonzalez FJ.

Kidney Int Rep. 2016 Sep;1(3):177-188. doi: 10.1016/j.ekir.2016.07.007. Epub 2016 Aug 5.

40.

In Vitro Glucuronidation of Wushanicaritin by Liver Microsomes, Intestine Microsomes and Expressed Human UDP-Glucuronosyltransferase Enzymes.

Hong X, Zheng Y, Qin Z, Wu B, Dai Y, Gao H, Yao Z, Gonzalez FJ, Yao X.

Int J Mol Sci. 2017 Sep 19;18(9). pii: E1983. doi: 10.3390/ijms18091983.

41.

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.

Li G, Xie C, Lu S, Nichols RG, Tian Y, Li L, Patel D, Ma Y, Brocker CN, Yan T, Krausz KW, Xiang R, Gavrilova O, Patterson AD, Gonzalez FJ.

Cell Metab. 2017 Oct 3;26(4):672-685.e4. doi: 10.1016/j.cmet.2017.08.019. Epub 2017 Sep 14.

PMID:
28918936
42.

Hepatocyte nuclear factor 4α regulates the expression of intestinal epithelial Na+/H+ exchanger isoform 3.

Muthusamy S, Jeong JJ, Cheng M, Bonzo JA, Kumar A, Gonzalez FJ, Borthakur A, Dudeja PK, Saksena S, Malakooti J.

Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1;314(1):G14-G21. doi: 10.1152/ajpgi.00225.2017. Epub 2017 Sep 7.

PMID:
28882825
43.

Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet.

Tanaka N, Takahashi S, Hu X, Lu Y, Fujimori N, Golla S, Fang ZZ, Aoyama T, Krausz KW, Gonzalez FJ.

Biochim Biophys Acta. 2017 Dec;1863(12):3170-3182. doi: 10.1016/j.bbadis.2017.08.017. Epub 2017 Aug 24.

PMID:
28844958
44.

A Western diet-induced mouse model reveals a possible mechanism by which metformin decreases obesity.

Gonzalez FJ, Jiang C.

Eur J Clin Pharmacol. 2017 Oct;73(10):1337-1339. doi: 10.1007/s00228-017-2322-3. Epub 2017 Aug 22. No abstract available.

PMID:
28831566
45.

Evaluation of liver fibrosis using Raman spectroscopy and infrared thermography: A pilot study.

Ramírez-Elías MG, Kolosovas-Machuca ES, Kershenobich D, Guzmán C, Escobedo G, González FJ.

Photodiagnosis Photodyn Ther. 2017 Sep;19:278-283. doi: 10.1016/j.pdpdt.2017.07.009. Epub 2017 Jul 25.

PMID:
28754542
46.

Inhibitory effects of fifteen phthalate esters in human cDNA-expressed UDP-glucuronosyltransferase supersomes.

Cao YF, Du Z, Zhu ZT, Sun HZ, Fu ZW, Yang K, Liu YZ, Hu CM, Dong PP, Gonzalez FJ, Fang ZZ.

Chemosphere. 2017 Oct;185:983-990. doi: 10.1016/j.chemosphere.2017.07.105. Epub 2017 Jul 19.

PMID:
28753904
47.

Lack of epithelial PPARγ causes cystic adenomatoid malformations in mouse fetal lung.

Kim JH, Yamaori S, Tanabe T, Takagi M, Matsubara T, Okamoto M, Kimura S, Gonzalez FJ.

Biochem Biophys Res Commun. 2017 Sep 16;491(2):271-276. doi: 10.1016/j.bbrc.2017.07.113. Epub 2017 Jul 21.

PMID:
28739257
48.

Orthogonal Comparison of GC-MS and 1H NMR Spectroscopy for Short Chain Fatty Acid Quantitation.

Cai J, Zhang J, Tian Y, Zhang L, Hatzakis E, Krausz KW, Smith PB, Gonzalez FJ, Patterson AD.

Anal Chem. 2017 Aug 1;89(15):7900-7906. doi: 10.1021/acs.analchem.7b00848. Epub 2017 Jul 12.

PMID:
28650151
49.

Inhibition of JNK signalling mediates PPARα-dependent protection against intrahepatic cholestasis by fenofibrate.

Dai M, Yang J, Xie M, Lin J, Luo M, Hua H, Xu G, Lin H, Song D, Cheng Y, Guo B, Zhao J, Gonzalez FJ, Liu A.

Br J Pharmacol. 2017 Sep;174(18):3000-3017. doi: 10.1111/bph.13928. Epub 2017 Aug 10.

PMID:
28646549
50.

Efficacy and safety of eslicarbazepine acetate monotherapy for partial-onset seizures: Experience from a multicenter, observational study.

Toledano R, Jovel CE, Jiménez-Huete A, Bayarri PG, Campos D, Gomariz EL, Giráldez BG, García-Morales I, Falip M, Agredano PM, Palao S, Prior MJAA, Pascual MRQ, Navacerrada FJ, González FJL, Ojeda J, Sáez AA, Bermejo PE, Gil-Nagel A.

Epilepsy Behav. 2017 Aug;73:173-179. doi: 10.1016/j.yebeh.2017.02.028. Epub 2017 Jun 20.

PMID:
28641170

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