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Action Generation Adapted to Low-Level and High-Level Robot-Object Interaction States.

Maestre C, Mukhtar G, Gonzales C, Doncieux S.

Front Neurorobot. 2019 Jul 24;13:56. doi: 10.3389/fnbot.2019.00056. eCollection 2019.


Curtailing Lead Aerosols: Effects of Primary Prevention on Declining Soil Lead and Children's Blood Lead in Metropolitan New Orleans.

Mielke HW, Gonzales CR, Powell ET.

Int J Environ Res Public Health. 2019 Jun 12;16(12). pii: E2068. doi: 10.3390/ijerph16122068.


Participation of lower-to-middle wage workers in a study of Chronic Disease Self-Management Program (CDSMP) effectiveness: Implications for reducing chronic disease burden among racial and ethnic minority populations.

Kneipp SM, Horrell L, Gonzales C, Linnan L, Lee Smith M, Brady T, Trogdon JG.

Public Health Nurs. 2019 Jun 5. doi: 10.1111/phn.12623. [Epub ahead of print]


Corrigendum to "Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types" [Bioorg. Med. Chem. 27 (1) (2019) 208-215].

De La Chapa J, Valdez M, Ruiz F 2nd, Gonzales K, Mitchell W, McHardy SF, Hart MJ, Polusani SR, Gonzales CB.

Bioorg Med Chem. 2019 Jun 1;27(11):2280. doi: 10.1016/j.bmc.2019.04.007. Epub 2019 Apr 20. No abstract available.


The novel capsazepine analog, CIDD-99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV1-independent induction of ER stress, mitochondrial dysfunction, and apoptosis.

De La Chapa JJ, Singha PK, Self KK, Sallaway ML, McHardy SF, Hart MJ, McGuff HS, Valdez MC, Ruiz F 2nd, Polusani SR, Gonzales CB.

J Oral Pathol Med. 2019 May;48(5):389-399. doi: 10.1111/jop.12843. Epub 2019 Apr 4.


Exploring the Interneuron Canopy Atop the 'Impenetrable Jungle'.

Chittajallu R, Gonzales CB, McBain CJ.

Trends Neurosci. 2019 Apr;42(4):237-239. doi: 10.1016/j.tins.2019.01.001. Epub 2019 Jan 31.


Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types.

De La Chapa J, Valdez M, Ruiz F 3rd, Gonzales K, Mitchell W, McHardy SF, Hart M, Polusani SR, Gonzales CB.

Bioorg Med Chem. 2019 Jan 1;27(1):208-215. doi: 10.1016/j.bmc.2018.11.040. Epub 2018 Nov 29. Erratum in: Bioorg Med Chem. 2019 Jun 1;27(11):2280.


Sub-lethal exposure to lead is associated with heightened aggression in an urban songbird.

McClelland SC, Durães Ribeiro R, Mielke HW, Finkelstein ME, Gonzales CR, Jones JA, Komdeur J, Derryberry E, Saltzberg EB, Karubian J.

Sci Total Environ. 2019 Mar 1;654:593-603. doi: 10.1016/j.scitotenv.2018.11.145. Epub 2018 Nov 11.


Current Practices of Intraventricular Antibiotic Therapy in the Treatment of Meningitis and Ventriculitis: Results from a Multicenter Retrospective Cohort Study.

Lewin JJ 3rd, Cook AM, Gonzales C, Merola D, Neyens R, Peppard WJ, Brophy GM, Kurczewski L, Giarratano M, Makii J, Rowe AS, Tesoro EP, Zaniewski A, Clark S, Ziai WC.

Neurocrit Care. 2019 Jun;30(3):609-616. doi: 10.1007/s12028-018-0647-0.


Physical Fitness Characteristics That Relate to Work Sample Test Battery Performance in Law Enforcement Recruits.

Lockie RG, Dawes JJ, Balfany K, Gonzales CE, Beitzel MM, Dulla JM, Orr RM.

Int J Environ Res Public Health. 2018 Nov 6;15(11). pii: E2477. doi: 10.3390/ijerph15112477.


Novel polygodial analogs P3 and P27: Efficacious therapeutic agents disrupting mitochondrial function in oral squamous cell carcinoma.

De La Chapa J, Singha PK, Sallaway M, Self K, Nasreldin R, Dasari R, Hart M, Kornienko A, Just J, Smith JA, Bissember AC, Gonzales CB.

Int J Oncol. 2018 Dec;53(6):2627-2636. doi: 10.3892/ijo.2018.4585. Epub 2018 Oct 5.


Impact of Personality Disorder Cluster on Depression Outcomes Within Collaborative Care Management Model of Care.

George MP, Garrison GM, Merten Z, Heredia D Jr, Gonzales C, Angstman KB.

J Prim Care Community Health. 2018 Jan-Dec;9:2150132718776877. doi: 10.1177/2150132718776877.


Thymol inhibits oral squamous cell carcinoma growth via mitochondria-mediated apoptosis.

De La Chapa JJ, Singha PK, Lee DR, Gonzales CB.

J Oral Pathol Med. 2018 Aug;47(7):674-682. doi: 10.1111/jop.12735. Epub 2018 Jun 9.


A Phase 1, Open-Label, Dose-Escalation Trial to Investigate Safety and Tolerability of Single Intravitreous Injections of ICON-1 Targeting Tissue Factor in Wet AMD.

Wells JA, Gonzales CR, Berger BB, Gonzalez VH, Sippy BD, Burian G.

Ophthalmic Surg Lasers Imaging Retina. 2018 May 1;49(5):336-345. doi: 10.3928/23258160-20180501-07.


Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation.

O'Neill BT, Beck EM, Butler CR, Nolan CE, Gonzales C, Zhang L, Doran SD, Lapham K, Buzon LM, Dutra JK, Barreiro G, Hou X, Martinez-Alsina LA, Rogers BN, Villalobos A, Murray JC, Ogilvie K, LaChapelle EA, Chang C, Lanyon LF, Steppan CM, Robshaw A, Hales K, Boucher GG, Pandher K, Houle C, Ambroise CW, Karanian D, Riddell D, Bales KR, Brodney MA.

J Med Chem. 2018 May 24;61(10):4476-4504. doi: 10.1021/acs.jmedchem.8b00246. Epub 2018 Apr 17.


[Antiurolithic Activity of the Ethanolic Extract of Ayacuchano Propolis in Rats].

López-Cabanillas R, Huayanay-Conde R, Gonzales C, Maguiña M, Granados I, Ccasani M, Laguna A, León E, Romero-Caballero N, Chacón J.

Rev Peru Med Exp Salud Publica. 2017 Oct-Dec;34(4):642-648. doi: 10.17843/rpmesp.2017.344.2730. Spanish.


Building bridges to enhance interpersonal relationships.

Ali S, Storozinski J, Gonzales C.

Can Nurse. 2017 Jan-Feb;113(1):34-5. No abstract available.


Missing the Mark? A Two Time Point Cohort Study Estimating Intestinal Parasite Prevalence in Informal Settlements in Lima, Peru.

Cooper MT, Searing RA, Thompson DM, Bard D, Carabin H, Gonzales C, Zavala C, Woodson K, Naifeh M.

Glob Pediatr Health. 2017 Nov 7;4:2333794X17739190. doi: 10.1177/2333794X17739190. eCollection 2017.


A Synthetic CD8α:MyD88 Coreceptor Enhances CD8+ T-cell Responses to Weakly Immunogenic and Lowly Expressed Tumor Antigens.

Kaczanowska S, Joseph AM, Guo J, Tsai AK, Lasola JJ, Younger K, Zhang Y, Gonzales CV, Davila E.

Cancer Res. 2017 Dec 15;77(24):7049-7058. doi: 10.1158/0008-5472.CAN-17-0653. Epub 2017 Oct 20.


Introspection Plays an Early Role in Children's Explicit Theory of Mind Development.

Gonzales CR, Fabricius WV, Kupfer AS.

Child Dev. 2018 Sep;89(5):1545-1552. doi: 10.1111/cdev.12876. Epub 2017 Jun 21.


The house fly Y Chromosome is young and minimally differentiated from its ancient X Chromosome partner.

Meisel RP, Gonzales CA, Luu H.

Genome Res. 2017 Aug;27(8):1417-1426. doi: 10.1101/gr.215509.116. Epub 2017 Jun 15.


Preclinical Evaluation of a Crown-Splinted Custom Root-Shaped Implant.

Kontogiorgos ED, Gharpure P, Iheanacho EO, Gonzales CJ, Opperman LA.

Int J Oral Maxillofac Implants. 2017 September/October;32(5):1023–1032. doi: 10.11607/jomi.5416. Epub 2017 May 18.


Soil Lead and Children's Blood Lead Disparities in Pre- and Post-Hurricane Katrina New Orleans (USA).

Mielke HW, Gonzales CR, Powell ET.

Int J Environ Res Public Health. 2017 Apr 12;14(4). pii: E407. doi: 10.3390/ijerph14040407.


The extent of root resorption and tooth movement following the application of ascending and descending magnetic forces: a prospective split mouth, microcomputed-tomography study.

Huang TTY, Elekdag-Turk S, Dalci O, Almuzian M, Karadeniz EI, Gonzales C, Petocz P, Turk T, Darendeliler MA.

Eur J Orthod. 2017 Oct 1;39(5):547-553. doi: 10.1093/ejo/cjw073.


Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality.

Butler CR, Ogilvie K, Martinez-Alsina L, Barreiro G, Beck EM, Nolan CE, Atchison K, Benvenuti E, Buzon L, Doran S, Gonzales C, Helal CJ, Hou X, Hsu MH, Johnson EF, Lapham K, Lanyon L, Parris K, O'Neill BT, Riddell D, Robshaw A, Vajdos F, Brodney MA.

J Med Chem. 2017 Jan 12;60(1):386-402. doi: 10.1021/acs.jmedchem.6b01451. Epub 2016 Dec 20.


"Providing a Roof" and More to Communities Affected by Typhoon Haiyan in the Philippines: the Médecins Sans Frontières Experience.

Ali E, Ferir MC, Reid T, Gray H, Van Den Boogaard W, Gonzales C, Zachariah R.

Disaster Med Public Health Prep. 2017 Jun;11(3):285-289. doi: 10.1017/dmp.2016.135. Epub 2016 Dec 15.


Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma.

Cannonier SA, Gonzales CB, Ely K, Guelcher SA, Sterling JA.

Oncotarget. 2016 Nov 15;7(46):76062-76075. doi: 10.18632/oncotarget.12584.


In-Vivo Detection and Tracking of T Cells in Various Organs in a Melanoma Tumor Model by 19F-Fluorine MRS/MRI.

Gonzales C, Yoshihara HA, Dilek N, Leignadier J, Irving M, Mieville P, Helm L, Michielin O, Schwitter J.

PLoS One. 2016 Oct 13;11(10):e0164557. doi: 10.1371/journal.pone.0164557. eCollection 2016.


Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression.

Plaisance I, Perruchoud S, Fernandez-Tenorio M, Gonzales C, Ounzain S, Ruchat P, Nemir M, Niggli E, Pedrazzini T.

JACC Basic Transl Sci. 2016 Oct;1(6):472-493. doi: 10.1016/j.jacbts.2016.06.008.


Patient experience assessment in pediatric hospitals in Argentina.

Dackiewicz N, Rodriguez S, Irazola V, Barani M, Marciano B, Fedrizzi V, Gonzales C, Elias-Costa C, Almada A, Viola B, Tonini S, Zamberlin N, Garcia-Elorrio E.

Int J Qual Health Care. 2016 Dec 1;28(6):675-681. doi: 10.1093/intqhc/mzw090.


Spatiotemporal dynamic transformations of soil lead and children's blood lead ten years after Hurricane Katrina: New grounds for primary prevention.

Mielke HW, Gonzales CR, Powell ET, Mielke PW Jr.

Environ Int. 2016 Sep;94:567-575. doi: 10.1016/j.envint.2016.06.017. Epub 2016 Jul 16.


Co-targeting ALK and EGFR parallel signaling in oral squamous cell carcinoma.

Gonzales CB, De La Chapa JJ, Saikumar P, Singha PK, Dybdal-Hargreaves NF, Chavez J, Horning AM, Parra J, Kirma NB.

Oral Oncol. 2016 Aug;59:12-19. doi: 10.1016/j.oraloncology.2016.05.007.


Characterization of perfluorocarbon relaxation times and their influence on the optimization of fluorine-19 MRI at 3 tesla.

Colotti R, Bastiaansen JAM, Wilson A, Flögel U, Gonzales C, Schwitter J, Stuber M, van Heeswijk RB.

Magn Reson Med. 2017 Jun;77(6):2263-2271. doi: 10.1002/mrm.26317. Epub 2016 Jul 6.


Hydropneumothorax in Children: A Rare Complication of a Bacterial Pneumonia.

Ortega C, Gonzales C, Soto-Martinez ME, Yock-Corrales A.

Case Rep Pediatr. 2016;2016:8097105. doi: 10.1155/2016/8097105. Epub 2016 May 9.


Varanoid Tooth Eruption and Implantation Modes in a Late Cretaceous Mosasaur.

Liu M, Reed DA, Cecchini GM, Lu X, Ganjawalla K, Gonzales CS, Monahan R, Luan X, Diekwisch TG.

Front Physiol. 2016 May 17;7:145. doi: 10.3389/fphys.2016.00145. eCollection 2016.


Children's Blood Lead Seasonality in Flint, Michigan (USA), and Soil-Sourced Lead Hazard Risks.

Laidlaw MA, Filippelli GM, Sadler RC, Gonzales CR, Ball AS, Mielke HW.

Int J Environ Res Public Health. 2016 Mar 25;13(4):358. doi: 10.3390/ijerph13040358. Review.


The Use of AngioVac for Symptomatic Aortic Thrombus Complicated by Mesenteric Ischemia.

Monastiriotis S, Gonzales C, Kokkosis A, Labropoulos N, Bilfinger T, Tassiopoulos AK.

Ann Vasc Surg. 2016 Apr;32:129.e1-6. doi: 10.1016/j.avsg.2015.09.026. Epub 2016 Jan 22.


Computerized physician order entry of a sedation protocol is not associated with improved sedation practice or outcomes in critically ill patients.

Haddad SH, Gonzales CB, Deeb AM, Tamim HM, AlDawood AS, Al Babtain I, Naidu BS, Arabi YM.

BMC Anesthesiol. 2015 Dec 7;15:177. doi: 10.1186/s12871-015-0161-2.


Impact of gender and menopausal status on metabolic parameters in chronic hepatitis C infection.

Gonzales CA, Bacchetti P, Khalili M.

J Viral Hepat. 2016 Mar;23(3):232-9. doi: 10.1111/jvh.12487. Epub 2015 Nov 10.


Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial against Drug-Resistant Cancer Cells.

Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A.

ChemMedChem. 2015 Dec;10(12):2014-26. doi: 10.1002/cmdc.201500360. Epub 2015 Oct 5.


CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis.

Ounzain S, Micheletti R, Arnan C, Plaisance I, Cecchi D, Schroen B, Reverter F, Alexanian M, Gonzales C, Ng SY, Bussotti G, Pezzuto I, Notredame C, Heymans S, Guigó R, Johnson R, Pedrazzini T.

J Mol Cell Cardiol. 2015 Dec;89(Pt A):98-112. doi: 10.1016/j.yjmcc.2015.09.016. Epub 2015 Sep 28.


A rapid and specific method for the detection of indole in complex biological samples.

Darkoh C, Chappell C, Gonzales C, Okhuysen P.

Appl Environ Microbiol. 2015 Dec;81(23):8093-7. doi: 10.1128/AEM.02787-15. Epub 2015 Sep 18.


Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary amines.

Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Kälin RE, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A.

Eur J Med Chem. 2015 Oct 20;103:226-37. doi: 10.1016/j.ejmech.2015.08.047. Epub 2015 Aug 29.


An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter.

Lucey BP, Gonzales C, Das U, Li J, Siemers ER, Slemmon JR, Bateman RJ, Huang Y, Fox GB, Claassen JA, Slats D, Verbeek MM, Tong G, Soares H, Savage MJ, Kennedy M, Forman M, Sjögren M, Margolin R, Chen X, Farlow MR, Dean RA, Waring JF.

Alzheimers Res Ther. 2015 Jul 29;7(1):53. doi: 10.1186/s13195-015-0136-z. eCollection 2015.


Effects of age and acute ethanol on glutamatergic neurotransmission in the medial prefrontal cortex of freely moving rats using enzyme-based microelectrode amperometry.

Mishra D, Harrison NR, Gonzales CB, Schilström B, Konradsson-Geuken Å.

PLoS One. 2015 Apr 30;10(4):e0125567. doi: 10.1371/journal.pone.0125567. eCollection 2015.


Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors.

Brodney MA, Beck EM, Butler CR, Barreiro G, Johnson EF, Riddell D, Parris K, Nolan CE, Fan Y, Atchison K, Gonzales C, Robshaw AE, Doran SD, Bundesmann MW, Buzon L, Dutra J, Henegar K, LaChapelle E, Hou X, Rogers BN, Pandit J, Lira R, Martinez-Alsina L, Mikochik P, Murray JC, Ogilvie K, Price L, Sakya SM, Yu A, Zhang Y, O'Neill BT.

J Med Chem. 2015 Apr 9;58(7):3223-52. doi: 10.1021/acs.jmedchem.5b00191. Epub 2015 Apr 1.


Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug design.

Butler CR, Brodney MA, Beck EM, Barreiro G, Nolan CE, Pan F, Vajdos F, Parris K, Varghese AH, Helal CJ, Lira R, Doran SD, Riddell DR, Buzon LM, Dutra JK, Martinez-Alsina LA, Ogilvie K, Murray JC, Young JM, Atchison K, Robshaw A, Gonzales C, Wang J, Zhang Y, O'Neill BT.

J Med Chem. 2015 Mar 26;58(6):2678-702. doi: 10.1021/jm501833t. Epub 2015 Mar 9.


Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human.

Rorick-Kehn LM, Witcher JW, Lowe SL, Gonzales CR, Weller MA, Bell RL, Hart JC, Need AB, McKinzie JH, Statnick MA, Suico JG, McKinzie DL, Tauscher-Wisniewski S, Mitch CH, Stoltz RR, Wong CJ.

Int J Neuropsychopharmacol. 2014 Oct 31;18(2). pii: pyu036. doi: 10.1093/ijnp/pyu036.

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