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Items: 17

1.

Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3.

Solania A, González-Páez GE, Wolan DW.

ACS Chem Biol. 2019 Aug 1. doi: 10.1021/acschembio.9b00564. [Epub ahead of print]

PMID:
31334631
2.

X-ray structure of an inactive zymogen clostripain-like protease from Parabacteroides distasonis.

González-Páez GE, Roncase EJ, Wolan DW.

Acta Crystallogr D Struct Biol. 2019 Mar 1;75(Pt 3):325-332. doi: 10.1107/S2059798319000809. Epub 2019 Feb 28.

PMID:
30950403
3.

X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors.

Roncase EJ, González-Páez GE, Wolan DW.

Biochemistry. 2019 Apr 2;58(13):1728-1737. doi: 10.1021/acs.biochem.9b00098. Epub 2019 Mar 14.

PMID:
30835452
4.

Substrate Profiling and High Resolution Co-complex Crystal Structure of a Secreted C11 Protease Conserved across Commensal Bacteria.

Roncase EJ, Moon C, Chatterjee S, González-Páez GE, Craik CS, O'Donoghue AJ, Wolan DW.

ACS Chem Biol. 2017 Jun 16;12(6):1556-1565. doi: 10.1021/acschembio.7b00143. Epub 2017 Apr 27.

5.

Proteome-wide covalent ligand discovery in native biological systems.

Backus KM, Correia BE, Lum KM, Forli S, Horning BD, González-Páez GE, Chatterjee S, Lanning BR, Teijaro JR, Olson AJ, Wolan DW, Cravatt BF.

Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.

6.

Identification and Co-complex Structure of a New S. pyogenes SpeB Small Molecule Inhibitor.

Wang AY, González-Páez GE, Wolan DW.

Biochemistry. 2015 Jul 21;54(28):4365-73. doi: 10.1021/acs.biochem.5b00607. Epub 2015 Jul 13.

PMID:
26132413
7.

Proteinases in excretory-secretory products of Toxocara canis second-stage larvae: zymography and modeling insights.

González-Páez GE, Alba-Hurtado F, García-Tovar CG, Argüello-García R.

Biomed Res Int. 2014;2014:418708. doi: 10.1155/2014/418708. Epub 2014 Aug 14.

8.

Discovery of a highly selective caspase-3 substrate for imaging live cells.

Vickers CJ, González-Páez GE, Wolan DW.

ACS Chem Biol. 2014 Oct 17;9(10):2199-203. doi: 10.1021/cb500586p. Epub 2014 Aug 20.

PMID:
25133295
9.

Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids.

Vickers CJ, González-Páez GE, Litwin KM, Umotoy JC, Coutsias EA, Wolan DW.

ACS Chem Biol. 2014 Oct 17;9(10):2194-8. doi: 10.1021/cb5004256. Epub 2014 Aug 5.

PMID:
25079698
10.

Identification of the Plasmodium berghei resistance locus 9 linked to survival on chromosome 9.

Bopp SE, Rodrigo E, González-Páez GE, Frazer M, Barnes SW, Valim C, Watson J, Walker JR, Schmedt C, Winzeler EA.

Malar J. 2013 Sep 11;12:316. doi: 10.1186/1475-2875-12-316.

11.

Selective detection and inhibition of active caspase-3 in cells with optimized peptides.

Vickers CJ, González-Páez GE, Wolan DW.

J Am Chem Soc. 2013 Aug 28;135(34):12869-76. doi: 10.1021/ja406399r. Epub 2013 Aug 19.

PMID:
23915420
12.

Small-molecule procaspase activators identified using fluorescence polarization.

Vickers CJ, González-Páez GE, Umotoy JC, Cayanan-Garrett C, Brown SJ, Wolan DW.

Chembiochem. 2013 Aug 19;14(12):1419-22. doi: 10.1002/cbic.201300315. Epub 2013 Jul 8.

PMID:
23836614
13.

Selective detection of caspase-3 versus caspase-7 using activity-based probes with key unnatural amino acids.

Vickers CJ, González-Páez GE, Wolan DW.

ACS Chem Biol. 2013 Jul 19;8(7):1558-66. doi: 10.1021/cb400209w. Epub 2013 May 3.

PMID:
23614665
14.

Ultrahigh and high resolution structures and mutational analysis of monomeric Streptococcus pyogenes SpeB reveal a functional role for the glycine-rich C-terminal loop.

González-Páez GE, Wolan DW.

J Biol Chem. 2012 Jul 13;287(29):24412-26. doi: 10.1074/jbc.M112.361576. Epub 2012 May 29.

15.

Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites.

Dharia NV, Plouffe D, Bopp SE, González-Páez GE, Lucas C, Salas C, Soberon V, Bursulaya B, Kochel TJ, Bacon DJ, Winzeler EA.

Genome Res. 2010 Nov;20(11):1534-44. doi: 10.1101/gr.105163.110. Epub 2010 Sep 9.

16.

Spiroindolones, a potent compound class for the treatment of malaria.

Rottmann M, McNamara C, Yeung BK, Lee MC, Zou B, Russell B, Seitz P, Plouffe DM, Dharia NV, Tan J, Cohen SB, Spencer KR, González-Páez GE, Lakshminarayana SB, Goh A, Suwanarusk R, Jegla T, Schmitt EK, Beck HP, Brun R, Nosten F, Renia L, Dartois V, Keller TH, Fidock DA, Winzeler EA, Diagana TT.

Science. 2010 Sep 3;329(5996):1175-80. doi: 10.1126/science.1193225.

17.

Toxocara canis: proteinases in perivitelline fluid from hatching eggs.

González-Páez GE, Argüello-García R, Alba-Hurtado F.

Vet Parasitol. 2007 Jul 20;147(3-4):332-5. Epub 2007 May 22.

PMID:
17517477

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