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Items: 35

1.

Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation.

Dalton WB, Helmenstine E, Walsh N, Gondek LP, Kelkar DS, Read A, Natrajan R, Christenson ES, Roman B, Das S, Zhao L, Leone RD, Shinn D, Groginski T, Madugundu AK, Patil A, Zabransky DJ, Medford A, Lee J, Cole AJ, Rosen M, Thakar M, Ambinder A, Donaldson J, DeZern AE, Cravero K, Chu D, Madero-Marroquin R, Pandey A, Hurley PJ, Lauring J, Park B.

J Clin Invest. 2019 Aug 8;130. pii: 125022. doi: 10.1172/JCI125022.

2.

The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopenia.

Zheng G, Chen P, Pallavajjalla A, Haley L, Gondek L, Dezern A, Ling H, De Marchi F, Lin MT, Gocke C.

Am J Hematol. 2019 Oct;94(10):1141-1148. doi: 10.1002/ajh.25592. Epub 2019 Aug 7.

PMID:
31350794
3.

Fibrinogen consumption and use of heparin are risk factors for delayed bleeding during acute promyelocytic leukemia induction.

Hambley BC, Norsworthy KJ, Jasem J, Zimmerman JW, Shenderov E, Webster JA, Showel MM, Gondek LP, Dalton WB, Prince G, Gladstone DE, Streiff MB, Pratz KW, Gojo I, Ghiaur G, Levis MJ, Smith BD, DeZern AE.

Leuk Res. 2019 Aug;83:106174. doi: 10.1016/j.leukres.2019.106174. Epub 2019 Jun 21. No abstract available.

PMID:
31255938
4.

Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity.

Lau BW, Huh K, Madero-Marroquin R, De Marchi F, Lim Y, Wang Q, Lobo F, Marchionni L, Smith DB, DeZern A, Levis MJ, Aplan PD, Matsui W, Gondek LP.

Oncogene. 2019 Jan;38(5):687-698. doi: 10.1038/s41388-018-0431-9. Epub 2018 Aug 31.

5.

Anthracycline-induced acute myocarditis and ventricular fibrillation arrest.

Pallazola VA, Murray JC, Al Harthy M, Zimmerman SL, Webster J, Gondek LP.

Am J Hematol. 2018 Mar;93(3):469-470. doi: 10.1002/ajh.24989. Epub 2017 Dec 18. No abstract available.

6.

Donor cell leukemia arising from clonal hematopoiesis after bone marrow transplantation.

Gondek LP, Zheng G, Ghiaur G, DeZern AE, Matsui W, Yegnasubramanian S, Lin MT, Levis M, Eshleman JR, Varadhan R, Tucker N, Jones R, Gocke CD.

Leukemia. 2016 Sep;30(9):1916-1920. doi: 10.1038/leu.2016.63. Epub 2016 Mar 15. No abstract available.

7.

Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.

Lim Y, Gondek L, Li L, Wang Q, Ma H, Chang E, Huso DL, Foerster S, Marchionni L, McGovern K, Watkins DN, Peacock CD, Levis M, Smith BD, Merchant AA, Small D, Matsui W.

Sci Transl Med. 2015 Jun 10;7(291):291ra96. doi: 10.1126/scitranslmed.aaa5731. Erratum in: Sci Transl Med. 2015 Jul 8;7(295):295er6. Ma, Haley [corrected to Ma, Hayley].

8.

I walk the line: how to tell MDS from other bone marrow failure conditions.

Gondek LP, DeZern AE.

Curr Hematol Malig Rep. 2014 Dec;9(4):389-99. doi: 10.1007/s11899-014-0224-3.

9.

Topography, clinical, and genomic correlates of 5q myeloid malignancies revisited.

Jerez A, Gondek LP, Jankowska AM, Makishima H, Przychodzen B, Tiu RV, O'Keefe CL, Mohamedali AM, Batista D, Sekeres MA, McDevitt MA, Mufti GJ, Maciejewski JP.

J Clin Oncol. 2012 Apr 20;30(12):1343-9. doi: 10.1200/JCO.2011.36.1824. Epub 2012 Feb 27.

10.

Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies.

Tiu RV, Gondek LP, O'Keefe CL, Elson P, Huh J, Mohamedali A, Kulasekararaj A, Advani AS, Paquette R, List AF, Sekeres MA, McDevitt MA, Mufti GJ, Maciejewski JP.

Blood. 2011 Apr 28;117(17):4552-60. doi: 10.1182/blood-2010-07-295857. Epub 2011 Feb 1.

11.

Characterization of chromosome arm 20q abnormalities in myeloid malignancies using genome-wide single nucleotide polymorphism array analysis.

Huh J, Tiu RV, Gondek LP, O'Keefe CL, Jasek M, Makishima H, Jankowska AM, Jiang Y, Verma A, Theil KS, McDevitt MA, Maciejewski JP.

Genes Chromosomes Cancer. 2010 Apr;49(4):390-9. doi: 10.1002/gcc.20748.

PMID:
20095039
12.

Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies.

Ye Y, McDevitt MA, Guo M, Zhang W, Galm O, Gore SD, Karp JE, Maciejewski JP, Kowalski J, Tsai HL, Gondek LP, Tsai HC, Wang X, Hooker C, Smith BD, Carraway HE, Herman JG.

Cancer Res. 2009 Nov 1;69(21):8482-90. doi: 10.1158/0008-5472.CAN-09-1153. Epub 2009 Oct 13.

13.

Clonal hematopoiesis in Philadelphia chromosome-negative bone marrow cells of chronic myeloid leukemia patients receiving dasatinib.

Paquette RL, Nicoll J, Chalukya M, Gondek L, Jasek M, Sawyers CL, Shah NP, Maciejewski J.

Leuk Res. 2010 Jun;34(6):708-13. doi: 10.1016/j.leukres.2009.08.032. Epub 2009 Oct 4.

14.

New lesions detected by single nucleotide polymorphism array-based chromosomal analysis have important clinical impact in acute myeloid leukemia.

Tiu RV, Gondek LP, O'Keefe CL, Huh J, Sekeres MA, Elson P, McDevitt MA, Wang XF, Levis MJ, Karp JE, Advani AS, Maciejewski JP.

J Clin Oncol. 2009 Nov 1;27(31):5219-26. doi: 10.1200/JCO.2009.21.9840. Epub 2009 Sep 21.

15.

TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p.

Jasek M, Gondek LP, Bejanyan N, Tiu R, Huh J, Theil KS, O'Keefe C, McDevitt MA, Maciejewski JP.

Leukemia. 2010 Jan;24(1):216-9. doi: 10.1038/leu.2009.189. Epub 2009 Sep 17. No abstract available.

16.

FISH and SNP-A karyotyping in myelodysplastic syndromes: improving cytogenetic detection of del(5q), monosomy 7, del(7q), trisomy 8 and del(20q).

Makishima H, Rataul M, Gondek LP, Huh J, Cook JR, Theil KS, Sekeres MA, Kuczkowski E, O'Keefe C, Maciejewski JP.

Leuk Res. 2010 Apr;34(4):447-53. doi: 10.1016/j.leukres.2009.08.023. Epub 2009 Sep 15.

17.

250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies.

Dunbar AJ, Gondek LP, O'Keefe CL, Makishima H, Rataul MS, Szpurka H, Sekeres MA, Wang XF, McDevitt MA, Maciejewski JP.

Cancer Res. 2008 Dec 15;68(24):10349-57. doi: 10.1158/0008-5472.CAN-08-2754.

18.

Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.

Jiang Y, Dunbar A, Gondek LP, Mohan S, Rataul M, O'Keefe C, Sekeres M, Saunthararajah Y, Maciejewski JP.

Blood. 2009 Feb 5;113(6):1315-25. doi: 10.1182/blood-2008-06-163246. Epub 2008 Oct 2.

19.

UPD1p indicates the presence of MPL W515L mutation in RARS-T, a mechanism analogous to UPD9p and JAK2 V617F mutation.

Szpurka H, Gondek LP, Mohan SR, Hsi ED, Theil KS, Maciejewski JP.

Leukemia. 2009 Mar;23(3):610-4. doi: 10.1038/leu.2008.249. Epub 2008 Sep 25. No abstract available.

PMID:
18818701
20.

Clonotype analysis of cytomegalovirus-specific cytotoxic T lymphocytes.

Babel N, Brestrich G, Gondek LP, Sattler A, Wlodarski MW, Poliak N, Bethke N, Thiel A, Hammer MH, Reinke P, Maciejewski JP.

J Am Soc Nephrol. 2009 Feb;20(2):344-52. doi: 10.1681/ASN.2007111225. Epub 2008 Sep 17.

21.

Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome.

Jankowska AM, Gondek LP, Szpurka H, Nearman ZP, Tiu RV, Maciejewski JP.

Leukemia. 2008 Mar;22(3):551-8. Epub 2007 Dec 6.

PMID:
18059482
22.

SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD.

Gondek LP, Dunbar AJ, Szpurka H, McDevitt MA, Maciejewski JP.

PLoS One. 2007 Nov 21;2(11):e1225.

23.

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML.

Gondek LP, Tiu R, O'Keefe CL, Sekeres MA, Theil KS, Maciejewski JP.

Blood. 2008 Feb 1;111(3):1534-42. Epub 2007 Oct 22.

24.

Detection of cryptic chromosomal lesions including acquired segmental uniparental disomy in advanced and low-risk myelodysplastic syndromes.

Gondek LP, Haddad AS, O'Keefe CL, Tiu R, Wlodarski MW, Sekeres MA, Theil KS, Maciejewski JP.

Exp Hematol. 2007 Nov;35(11):1728-38. Epub 2007 Oct 17.

PMID:
17920760
25.

Evidence for genetic susceptibility towards development of posttransplant lymphoproliferative disorder in solid organ recipients.

Babel N, Vergopoulos A, Trappe RU, Oertel S, Hammer MH, Karaivanov S, Schneider N, Riess H, Papp-Vary M, Neuhaus R, Gondek LP, Volk HD, Reinke P.

Transplantation. 2007 Aug 15;84(3):387-91.

PMID:
17700165
26.

Molecular analysis of alloreactive CTL post-hemopoietic stem cell transplantation.

O'Keefe CL, Gondek L, Davis R, Kuczkowski E, Sobecks RM, Rodriguez A, Narvaez Y, McIver Z, Tuthill R, Laughlin M, Bolwell B, Maciejewski JP.

J Immunol. 2007 Aug 1;179(3):2013-22.

27.

Multiple magnetic phase transitions in Tb(3)Cu(4)Si(4).

Gondek L, Szytuła A, Kaczorowski D, Szewczyk A, Gutowska M, Piekarz P.

J Phys Condens Matter. 2007 Jun 20;19(24):246225. doi: 10.1088/0953-8984/19/24/246225. Epub 2007 May 30.

PMID:
21694068
28.

Clonality of the stem cell compartment during evolution of myelodysplastic syndromes and other bone marrow failure syndromes.

Tiu R, Gondek L, O'Keefe C, Maciejewski JP.

Leukemia. 2007 Aug;21(8):1648-57. Epub 2007 Jun 7. Review.

PMID:
17554386
29.

Single nucleotide polymorphism arrays complement metaphase cytogenetics in detection of new chromosomal lesions in MDS.

Gondek LP, Tiu R, Haddad AS, O'Keefe CL, Sekeres MA, Theil KS, Maciejewski JP.

Leukemia. 2007 Sep;21(9):2058-61. Epub 2007 May 24. No abstract available.

PMID:
17525728
30.

Immune-mediated bone marrow failure syndromes of progenitor and stem cells: molecular analysis of cytotoxic T cell clones.

Maciejewski JP, O'Keefe C, Gondek L, Tiu R.

Folia Histochem Cytobiol. 2007;45(1):5-14. Review.

31.

High-resolution genomic arrays facilitate detection of novel cryptic chromosomal lesions in myelodysplastic syndromes.

O'Keefe CL, Tiu R, Gondek LP, Powers J, Theil KS, Kalaycio M, Lichtin A, Sekeres MA, Maciejewski JP.

Exp Hematol. 2007 Feb;35(2):240-51.

32.

Molecular strategies for detection and quantitation of clonal cytotoxic T-cell responses in aplastic anemia and myelodysplastic syndrome.

Wlodarski MW, Gondek LP, Nearman ZP, Plasilova M, Kalaycio M, Hsi ED, Maciejewski JP.

Blood. 2006 Oct 15;108(8):2632-41. Epub 2006 Apr 13.

33.

Analysis of laser lipolysis effects on human tissue samples obtained from liposuction.

Badin AZ, Gondek LB, Garcia MJ, Valle LC, Flizikowski FB, de Noronha L.

Aesthetic Plast Surg. 2005 Jul-Aug;29(4):281-6. Epub 2005 Jul 19.

PMID:
16075355
34.

Efficient identification of T-cell clones associated with graft-versus-host disease in target tissue allows for subsequent detection in peripheral blood.

Beck RC, Wlodarski M, Gondek L, Theil KS, Tuthill RJ, Sobeck R, Bolwell B, Maciejewski JP.

Br J Haematol. 2005 May;129(3):411-9.

PMID:
15842666
35.

Laser lipolysis: flaccidity under control.

Badin AZ, Moraes LM, Gondek L, Chiaratti MG, Canta L.

Aesthetic Plast Surg. 2002 Sep-Oct;26(5):335-9.

PMID:
12432470

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