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Items: 1 to 50 of 124

1.

MYB regulates the DNA damage response and components of the homology-directed repair pathway in human estrogen receptor-positive breast cancer cells.

Yang RM, Nanayakkara D, Kalimutho M, Mitra P, Khanna KK, Dray E, Gonda TJ.

Oncogene. 2019 Jun;38(26):5239-5249. doi: 10.1038/s41388-019-0789-3. Epub 2019 Apr 10.

PMID:
30971760
2.

Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules.

Artuz CM, Knights AJ, Funnell APW, Gonda TJ, Ravid K, Pearson RCM, Quinlan KGR, Crossley M.

Biotechnol Rep (Amst). 2018 Oct 2;20:e00285. doi: 10.1016/j.btre.2018.e00285. eCollection 2018 Dec.

3.

Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia.

Maung KZY, Leo PJ, Bassal M, Casolari DA, Gray JX, Bray SC, Pederson S, Singhal D, Samaraweera SE, Nguyen T, Cildir G, Marshall M, Ewing A, Duncan EL, Brown MA, Saal R, Tergaonkar V, To LB, Marlton P, Gill D, Lewis I, Deans AJ, Brown AL, D'Andrea RJ, Gonda TJ.

Blood Cancer J. 2018 Jun 1;8(6):50. doi: 10.1038/s41408-018-0090-7. No abstract available.

4.

Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells.

Jamaludin SYN, Azimi I, Davis FM, Peters AA, Gonda TJ, Thompson EW, Roberts-Thomson SJ, Monteith GR.

Oncol Lett. 2018 Apr;15(4):4289-4295. doi: 10.3892/ol.2018.7827. Epub 2018 Jan 19.

5.

Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells.

Peters AA, Jamaludin SYN, Yapa KTDS, Chalmers S, Wiegmans AP, Lim HF, Milevskiy MJG, Azimi I, Davis FM, Northwood KS, Pera E, Marcial DL, Dray E, Waterhouse NJ, Cabot PJ, Gonda TJ, Kenny PA, Brown MA, Khanna KK, Roberts-Thomson SJ, Monteith GR.

Oncogene. 2017 Nov 16;36(46):6490-6500. doi: 10.1038/onc.2017.234. Epub 2017 Jul 31.

PMID:
28759041
6.

Ectodermal-Neural Cortex 1 Isoforms Have Contrasting Effects on MC3T3-E1 Osteoblast Mineralization and Gene Expression.

Worton LE, Shi YC, Smith EJ, Barry SC, Gonda TJ, Whitehead JP, Gardiner EM.

J Cell Biochem. 2017 Aug;118(8):2141-2150. doi: 10.1002/jcb.25851. Epub 2017 Apr 18.

PMID:
27996212
7.

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer.

Škalamera D, Dahmer-Heath M, Stevenson AJ, Pinto C, Shah ET, Daignault SM, Said NA, Davis M, Haass NK, Williams ED, Hollier BG, Thompson EW, Gabrielli B, Gonda TJ.

Oncotarget. 2016 Sep 20;7(38):61000-61020. doi: 10.18632/oncotarget.11314.

8.

Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma.

Lee WJ, Škalamera D, Dahmer-Heath M, Shakhbazov K, Ranall MV, Fox C, Lambie D, Stevenson AJ, Yaswen P, Gonda TJ, Gabrielli B.

SLAS Discov. 2017 Mar;22(3):298-308. doi: 10.1177/1087057116679592. Epub 2016 Nov 23.

9.

Adenoid Cystic Carcinoma Can Be Driven by MYB or MYBL1 Rearrangements: New Insights into MYB and Tumor Biology.

Gonda TJ, Ramsay RG.

Cancer Discov. 2016 Feb;6(2):125-7. doi: 10.1158/2159-8290.CD-15-1470.

10.

CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression.

Mitra P, Yang RM, Sutton J, Ramsay RG, Gonda TJ.

Oncotarget. 2016 Feb 23;7(8):9069-83. doi: 10.18632/oncotarget.6997.

11.

Aurora A Is Critical for Survival in HPV-Transformed Cervical Cancer.

Gabrielli B, Bokhari F, Ranall MV, Oo ZY, Stevenson AJ, Wang W, Murrell M, Shaikh M, Fallaha S, Clarke D, Kelly M, Sedelies K, Christensen M, McKee S, Leggatt G, Leo P, Skalamera D, Soyer HP, Gonda TJ, McMillan NA.

Mol Cancer Ther. 2015 Dec;14(12):2753-61. doi: 10.1158/1535-7163.MCT-15-0506. Epub 2015 Oct 29.

12.

Directly targeting transcriptional dysregulation in cancer.

Gonda TJ, Ramsay RG.

Nat Rev Cancer. 2015 Nov;15(11):686-94. doi: 10.1038/nrc4018. Review.

PMID:
26493648
13.

MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region.

Pereira LA, Hugo HJ, Malaterre J, Huiling X, Sonza S, Cures A, Purcell DF, Ramsland PA, Gerondakis S, Gonda TJ, Ramsay RG.

PLoS One. 2015 Apr 8;10(4):e0122919. doi: 10.1371/journal.pone.0122919. eCollection 2015.

14.

Gateway-compatible vectors for high-throughput protein expression in pro- and eukaryotic cell-free systems.

Gagoski D, Mureev S, Giles N, Johnston W, Dahmer-Heath M, Škalamera D, Gonda TJ, Alexandrov K.

J Biotechnol. 2015 Feb 10;195:1-7. doi: 10.1016/j.jbiotec.2014.12.006. Epub 2014 Dec 19.

PMID:
25529348
15.

Decatenation checkpoint-defective melanomas are dependent on PI3K for survival.

Brooks K, Ranall M, Spoerri L, Stevenson A, Gunasingh G, Pavey S, Meunier F, Gonda TJ, Gabrielli B.

Pigment Cell Melanoma Res. 2014 Sep;27(5):813-21. doi: 10.1111/pcmr.12268. Epub 2014 Jun 23.

PMID:
24890688
16.

Rapid mapping of interactions between Human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy.

Sierecki E, Stevers LM, Giles N, Polinkovsky ME, Moustaqil M, Mureev S, Johnston WA, Dahmer-Heath M, Skalamera D, Gonda TJ, Gabrielli B, Collins BM, Alexandrov K, Gambin Y.

Mol Cell Proteomics. 2014 Sep;13(9):2233-45. doi: 10.1074/mcp.M113.037275. Epub 2014 May 27.

17.

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes.

Pattabiraman DR, McGirr C, Shakhbazov K, Barbier V, Krishnan K, Mukhopadhyay P, Hawthorne P, Trezise A, Ding J, Grimmond SM, Papathanasiou P, Alexander WS, Perkins AC, Levesque JP, Winkler IG, Gonda TJ.

Blood. 2014 Apr 24;123(17):2682-90. doi: 10.1182/blood-2012-02-413187. Epub 2014 Mar 4.

18.

Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells.

Hugo HJ, Pereira L, Suryadinata R, Drabsch Y, Gonda TJ, Gunasinghe NP, Pinto C, Soo ET, van Denderen BJ, Hill P, Ramsay RG, Sarcevic B, Newgreen DF, Thompson EW.

Breast Cancer Res. 2013 Nov 27;15(6):R113. doi: 10.1186/bcr3580.

19.

The MYB proto-oncogene suppresses monocytic differentiation of acute myeloid leukemia cells via transcriptional activation of its target gene GFI1.

Zhao L, Ye P, Gonda TJ.

Oncogene. 2014 Aug 28;33(35):4442-9. doi: 10.1038/onc.2013.419. Epub 2013 Oct 14.

PMID:
24121275
20.

MYB down-regulation enhances sensitivity of U937 myeloid leukemia cells to the histone deacetylase inhibitor LBH589 in vitro and in vivo.

Ye P, Zhao L, McGirr C, Gonda TJ.

Cancer Lett. 2014 Feb 1;343(1):98-106. doi: 10.1016/j.canlet.2013.09.022. Epub 2013 Sep 26.

PMID:
24075958
21.

The MYB oncogene can suppress apoptosis in acute myeloid leukemia cells by transcriptional repression of DRAK2 expression.

Ye P, Zhao L, Gonda TJ.

Leuk Res. 2013 May;37(5):595-601. doi: 10.1016/j.leukres.2013.01.012. Epub 2013 Feb 8.

PMID:
23398943
22.

Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of human ORFs and identification of human genes affecting viral titer.

Škalamera D, Dahmer M, Purdon AS, Wilson BM, Ranall MV, Blumenthal A, Gabrielli B, Gonda TJ.

PLoS One. 2012;7(12):e51733. doi: 10.1371/journal.pone.0051733. Epub 2012 Dec 12.

23.

Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor.

Mori S, Bernardi R, Laurent A, Resnati M, Crippa A, Gabrieli A, Keough R, Gonda TJ, Blasi F.

PLoS One. 2012;7(10):e39723. doi: 10.1371/journal.pone.0039723. Epub 2012 Oct 8.

24.

Role and potential for therapeutic targeting of MYB in leukemia.

Pattabiraman DR, Gonda TJ.

Leukemia. 2013 Feb;27(2):269-77. doi: 10.1038/leu.2012.225. Epub 2012 Aug 9. Review.

PMID:
22874877
25.

Morphological and molecular analysis of a breast cancer cluster at the ABC Studio in Toowong.

Waddell N, Stein SR, Wagner SA, Bennett I, Djougarian A, Melana S, Jaffer S, Holland JF, Pogo BG, Gonda TJ, Brown MA, Leo P, Saunders NA, McMillan NA, Cocciardi S, Vargas AC, Lakhani SR, Chenevix-Trench G, Newman B, Francis GD.

Pathology. 2012 Aug;44(5):469-72. doi: 10.1097/PAT.0b013e3283559e67. No abstract available.

PMID:
22744170
26.

Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA.

Hochstatter J, Hölzel M, Rohrmoser M, Schermelleh L, Leonhardt H, Keough R, Gonda TJ, Imhof A, Eick D, Längst G, Németh A.

J Biol Chem. 2012 Jul 13;287(29):24365-77. doi: 10.1074/jbc.M111.303719. Epub 2012 May 29.

27.

Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene.

Mitra P, Pereira LA, Drabsch Y, Ramsay RG, Gonda TJ.

Nucleic Acids Res. 2012 Jul;40(13):5988-6000. doi: 10.1093/nar/gks286. Epub 2012 Apr 5.

28.

The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation.

Brown AL, Salerno DG, Sadras T, Engler GA, Kok CH, Wilkinson CR, Samaraweera SE, Sadlon TJ, Perugini M, Lewis ID, Gonda TJ, D'Andrea RJ.

Differentiation. 2012 Jan;83(1):47-59. doi: 10.1016/j.diff.2011.08.003. Epub 2011 Oct 8.

29.

MYB is essential for mammary tumorigenesis.

Miao RY, Drabsch Y, Cross RS, Cheasley D, Carpinteri S, Pereira L, Malaterre J, Gonda TJ, Anderson RL, Ramsay RG.

Cancer Res. 2011 Nov 15;71(22):7029-37. doi: 10.1158/0008-5472.CAN-11-1015. Epub 2011 Sep 26.

30.

High-content imaging of neutral lipid droplets with 1,6-diphenylhexatriene.

Ranall MV, Gabrielli BG, Gonda TJ.

Biotechniques. 2011 Jul;51(1):35-6, 38-42. doi: 10.2144/000113702.

31.

A high-throughput platform for lentiviral overexpression screening of the human ORFeome.

Škalamera D, Ranall MV, Wilson BM, Leo P, Purdon AS, Hyde C, Nourbakhsh E, Grimmond SM, Barry SC, Gabrielli B, Gonda TJ.

PLoS One. 2011;6(5):e20057. doi: 10.1371/journal.pone.0020057. Epub 2011 May 24.

32.

Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb.

Zhao L, Glazov EA, Pattabiraman DR, Al-Owaidi F, Zhang P, Brown MA, Leo PJ, Gonda TJ.

Nucleic Acids Res. 2011 Jun;39(11):4664-79. doi: 10.1093/nar/gkr024. Epub 2011 Feb 11.

33.

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models.

Dredge K, Hammond E, Handley P, Gonda TJ, Smith MT, Vincent C, Brandt R, Ferro V, Bytheway I.

Br J Cancer. 2011 Feb 15;104(4):635-42. doi: 10.1038/bjc.2011.11. Epub 2011 Feb 1.

34.

A functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming ability.

Saether T, Pattabiraman DR, Alm-Kristiansen AH, Vogt-Kielland LT, Gonda TJ, Gabrielsen OS.

Oncogene. 2011 Jan 13;30(2):212-22. doi: 10.1038/onc.2010.397. Epub 2010 Aug 30.

PMID:
20802522
35.

MYB suppresses differentiation and apoptosis of human breast cancer cells.

Drabsch Y, Robert RG, Gonda TJ.

Breast Cancer Res. 2010;12(4):R55. doi: 10.1186/bcr2614. Epub 2010 Jul 26.

36.

Robust, reversible gene knockdown using a single lentiviral short hairpin RNA vector.

Brown CY, Sadlon T, Gargett T, Melville E, Zhang R, Drabsch Y, Ling M, Strathdee CA, Gonda TJ, Barry SC.

Hum Gene Ther. 2010 Aug;21(8):1005-17. doi: 10.1089/hum.2009.107.

PMID:
20615123
37.

A recessive screen for genes regulating hematopoietic stem cells.

Papathanasiou P, Tunningley R, Pattabiraman DR, Ye P, Gonda TJ, Whittle B, Hamilton AE, Cridland SO, Lourie R, Perkins AC.

Blood. 2010 Dec 23;116(26):5849-58. doi: 10.1182/blood-2010-04-269951. Epub 2010 Jul 7.

38.

Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high-throughput screening.

Ranall MV, Gabrielli BG, Gonda TJ.

Biotechniques. 2010 May;48(5):379-86. doi: 10.2144/000113410.

39.

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit.

Perugini M, Brown AL, Salerno DG, Booker GW, Stojkoski C, Hercus TR, Lopez AF, Hibbs ML, Gonda TJ, D'Andrea RJ.

Blood. 2010 Apr 22;115(16):3346-53. doi: 10.1182/blood-2009-08-235846. Epub 2010 Feb 19.

40.

Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth.

Johnstone KD, Karoli T, Liu L, Dredge K, Copeman E, Li CP, Davis K, Hammond E, Bytheway I, Kostewicz E, Chiu FC, Shackleford DM, Charman SA, Charman WN, Harenberg J, Gonda TJ, Ferro V.

J Med Chem. 2010 Feb 25;53(4):1686-99. doi: 10.1021/jm901449m.

PMID:
20128596
41.

The SMN interactome includes Myb-binding protein 1a.

Fuller HR, Man NT, Lam le T, Thanh le T, Keough RA, Asperger A, Gonda TJ, Morris GE.

J Proteome Res. 2010 Jan;9(1):556-63. doi: 10.1021/pr900884g.

PMID:
19928837
42.

Mutations in multiple domains of c-Myb disrupt interaction with CBP/p300 and abrogate myeloid transforming ability.

Pattabiraman DR, Sun J, Dowhan DH, Ishii S, Gonda TJ.

Mol Cancer Res. 2009 Sep;7(9):1477-86. doi: 10.1158/1541-7786.MCR-09-0070. Epub 2009 Sep 8.

43.

Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling.

Ciznadija D, Tothill R, Waterman ML, Zhao L, Huynh D, Yu RM, Ernst M, Ishii S, Mantamadiotis T, Gonda TJ, Ramsay RG, Malaterre J.

Cell Death Differ. 2009 Nov;16(11):1530-8. doi: 10.1038/cdd.2009.94. Epub 2009 Jul 17.

44.

The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy.

Dredge K, Hammond E, Davis K, Li CP, Liu L, Johnstone K, Handley P, Wimmer N, Gonda TJ, Gautam A, Ferro V, Bytheway I.

Invest New Drugs. 2010 Jun;28(3):276-83. doi: 10.1007/s10637-009-9245-5. Epub 2009 Apr 9.

PMID:
19357810
45.

Repression of Gadd45alpha by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation.

Perugini M, Kok CH, Brown AL, Wilkinson CR, Salerno DG, Young SM, Diakiw SM, Lewis ID, Gonda TJ, D'Andrea RJ.

Leukemia. 2009 Apr;23(4):729-38. doi: 10.1038/leu.2008.349. Epub 2009 Jan 8.

PMID:
19151789
46.

MYB function in normal and cancer cells.

Ramsay RG, Gonda TJ.

Nat Rev Cancer. 2008 Jul;8(7):523-34. doi: 10.1038/nrc2439. Review.

PMID:
18574464
47.

Lack of reproducible growth inhibition by Schlafen1 and Schlafen2 in vitro.

Zhao L, Neumann B, Murphy K, Silke J, Gonda TJ.

Blood Cells Mol Dis. 2008 Sep-Oct;41(2):188-93. doi: 10.1016/j.bcmd.2008.03.006. Epub 2008 May 13.

PMID:
18479948
48.

Estrogen and MYB in breast cancer: potential for new therapies.

Gonda TJ, Leo P, Ramsay RG.

Expert Opin Biol Ther. 2008 Jun;8(6):713-7. doi: 10.1517/14712598.8.6.713 . Review.

PMID:
18476782
49.

Subcellular localization of the Schlafen protein family.

Neumann B, Zhao L, Murphy K, Gonda TJ.

Biochem Biophys Res Commun. 2008 May 23;370(1):62-6. doi: 10.1016/j.bbrc.2008.03.032. Epub 2008 Mar 18.

PMID:
18355440
50.

Ribosomal stress induces processing of Mybbp1a and its translocation from the nucleolus to the nucleoplasm.

Yamauchi T, Keough RA, Gonda TJ, Ishii S.

Genes Cells. 2008 Jan;13(1):27-39. doi: 10.1111/j.1365-2443.2007.01148.x.

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