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Items: 1 to 50 of 160

1.

Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia.

Belcher JD, Gomperts E, Nguyen J, Chen C, Abdulla F, Kiser ZM, Gallo D, Levy H, Otterbein LE, Vercellotti GM.

PLoS One. 2018 Oct 11;13(10):e0205194. doi: 10.1371/journal.pone.0205194. eCollection 2018.

2.

Carbon monoxide protects the kidney through the central circadian clock and CD39.

Correa-Costa M, Gallo D, Csizmadia E, Gomperts E, Lieberum JL, Hauser CJ, Ji X, Wang B, Câmara NOS, Robson SC, Otterbein LE.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2302-E2310. doi: 10.1073/pnas.1716747115. Epub 2018 Feb 20.

3.

Pharmacokinetics, safety and efficacy of a recombinant factor IX product, trenonacog alfa in previously treated haemophilia B patients.

Collins PW, Quon DVK, Makris M, Chowdary P, Kempton CL, Apte SJ, Ramanan MV, Hay CRM, Drobic B, Hua Y, Babinchak TJ, Gomperts ED.

Haemophilia. 2018 Jan;24(1):104-112. doi: 10.1111/hae.13324. Epub 2017 Aug 17.

4.

The role of carbon monoxide and heme oxygenase in the prevention of sickle cell disease vaso-occlusive crises.

Gomperts E, Belcher JD, Otterbein LE, Coates TD, Wood J, Skolnick BE, Levy H, Vercellotti GM.

Am J Hematol. 2017 Jun;92(6):569-582. doi: 10.1002/ajh.24750. Epub 2017 Apr 29. Review.

5.

The importance of genetic factors for the development of arthropathy: a longitudinal study of children and adolescents with haemophilia A.

Gomperts ED, Schwarz J, Donfield SM, Lail AE, Astermark J, Hoots WK, Winkler CA, Berntorp E.

Thromb Haemost. 2017 Jan 26;117(2):277-285. doi: 10.1160/TH16-06-0440. Epub 2016 Dec 8.

PMID:
27929201
6.

Evaluation of Viremia Frequencies of a Novel Human Pegivirus by Using Bioinformatic Screening and PCR.

Bonsall D, Gregory WF, Ip CL, Donfield S, Iles J, Ansari MA, Piazza P, Trebes A, Brown A, Frater J, Pybus OG, Goulder P, Klenerman P, Bowden R, Gomperts ED, Barnes E, Kapoor A, Sharp CP, Simmonds P.

Emerg Infect Dis. 2016 Apr;22(4):671-8. doi: 10.3201/eid2204.151812.

7.

Recombinant B domain deleted porcine factor VIII for the treatment of bleeding episodes in adults with acquired hemophilia A.

Gomperts E.

Expert Rev Hematol. 2015 Aug;8(4):427-32. doi: 10.1586/17474086.2015.1040758. Epub 2015 Apr 30. Review.

PMID:
25927594
8.

Efficacy and safety of OBI-1, an antihaemophilic factor VIII (recombinant), porcine sequence, in subjects with acquired haemophilia A.

Kruse-Jarres R, St-Louis J, Greist A, Shapiro A, Smith H, Chowdary P, Drebes A, Gomperts E, Bourgeois C, Mo M, Novack A, Farin H, Ewenstein B.

Haemophilia. 2015 Mar;21(2):162-70. doi: 10.1111/hae.12627. Epub 2015 Jan 27.

PMID:
25623166
9.

GWATCH: a web platform for automated gene association discovery analysis.

Svitin A, Malov S, Cherkasov N, Geerts P, Rotkevich M, Dobrynin P, Shevchenko A, Guan L, Troyer J, Hendrickson S, Dilks HH, Oleksyk TK, Donfield S, Gomperts E, Jabs DA, Sezgin E, Van Natta M, Harrigan PR, Brumme ZL, O'Brien SJ.

Gigascience. 2014 Nov 5;3:18. doi: 10.1186/2047-217X-3-18. eCollection 2014.

10.

The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Astermark J, Donfield SM, Gomperts ED, Schwarz J, Menius ED, Pavlova A, Oldenburg J, Kessing B, DiMichele DM, Shapiro AD, Winkler CA, Berntorp E; Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Blood. 2013 Feb 21;121(8):1446-54. doi: 10.1182/blood-2012-06-434803. Epub 2012 Dec 6.

11.

F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Schwarz J, Astermark J, Menius ED, Carrington M, Donfield SM, Gomperts ED, Nelson GW, Oldenburg J, Pavlova A, Shapiro AD, Winkler CA, Berntorp E; Hemophilia Inhibitor Genetics Study Combined Cohort.

Haemophilia. 2013 Jan;19(1):113-8. doi: 10.1111/hae.12004. Epub 2012 Sep 7.

12.

Pharmacokinetic properties of IB1001, an investigational recombinant factor IX, in patients with haemophilia B: repeat pharmacokinetic evaluation and sialylation analysis.

Martinowitz U, Shapiro A, Quon DV, Escobar M, Kempton C, Collins PW, Chowdary P, Makris M, Mannucci PM, Morfini M, Valentino LA, Gomperts E, Lee M.

Haemophilia. 2012 Nov;18(6):881-7. doi: 10.1111/j.1365-2516.2012.02897.x. Epub 2012 Jul 5.

PMID:
22764744
13.

Virologic and clinical features of primary infection with human parvovirus 4 in subjects with hemophilia: frequent transmission by virally inactivated clotting factor concentrates.

Sharp CP, Lail A, Donfield S, Gomperts ED, Simmonds P.

Transfusion. 2012 Jul;52(7):1482-9. doi: 10.1111/j.1537-2995.2011.03420.x. Epub 2011 Nov 2.

PMID:
22043925
14.

Modeling costs and outcomes associated with a treatment algorithm for problem bleeding episodes in patients with severe hemophilia a and high-titer inhibitors.

Bonnet P, Gringeri A, Gomperts E, Leissinger CA, d'Oiron R, Teitel J, Young G, Franklin M, Ewenstein B, Berntorp E.

Am Health Drug Benefits. 2011 Jul;4(4):219-31.

15.

Genome-wide association study implicates PARD3B-based AIDS restriction.

Troyer JL, Nelson GW, Lautenberger JA, Chinn L, McIntosh C, Johnson RC, Sezgin E, Kessing B, Malasky M, Hendrickson SL, Li G, Pontius J, Tang M, An P, Winkler CA, Limou S, Le Clerc S, Delaneau O, Zagury JF, Schuitemaker H, van Manen D, Bream JH, Gomperts ED, Buchbinder S, Goedert JJ, Kirk GD, O'Brien SJ.

J Infect Dis. 2011 May 15;203(10):1491-502. doi: 10.1093/infdis/jir046.

16.

Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection.

Chinn LW, Tang M, Kessing BD, Lautenberger JA, Troyer JL, Malasky MJ, McIntosh C, Kirk GD, Wolinsky SM, Buchbinder SP, Gomperts ED, Goedert JJ, O'Brien SJ.

J Infect Dis. 2010 Dec 15;202(12):1836-45. doi: 10.1086/657322.

17.

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ.

PLoS One. 2010 Sep 21;5(9):e12862. doi: 10.1371/journal.pone.0012862.

18.

von Willebrand factor: what is its role in the immune response in haemophilia?

Kaveri S, Mannucci PM, Kurth MH, Ewing N, Kessler CM, Nugent DJ, Gomperts ED.

Haemophilia. 2011 Jan;17(1):e235-8. doi: 10.1111/j.1365-2516.2010.02277.x. No abstract available.

PMID:
20546026
19.

High frequencies of exposure to the novel human parvovirus PARV4 in hemophiliacs and injection drug users, as detected by a serological assay for PARV4 antibodies.

Sharp CP, Lail A, Donfield S, Simmons R, Leen C, Klenerman P, Delwart E, Gomperts ED, Simmonds P.

J Infect Dis. 2009 Oct 1;200(7):1119-25. doi: 10.1086/605646.

20.

Quantitation of anti-factor VIII antibodies in human plasma.

Krudysz-Amblo J, Parhami-Seren B, Butenas S, Brummel-Ziedins KE, Gomperts ED, Rivard GE, Mann KG.

Blood. 2009 Mar 12;113(11):2587-94. doi: 10.1182/blood-2008-08-174987. Epub 2009 Jan 14.

21.

Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients.

Kuntzen T, Timm J, Berical A, Lennon N, Berlin AM, Young SK, Lee B, Heckerman D, Carlson J, Reyor LL, Kleyman M, McMahon CM, Birch C, Schulze Zur Wiesch J, Ledlie T, Koehrsen M, Kodira C, Roberts AD, Lauer GM, Rosen HR, Bihl F, Cerny A, Spengler U, Liu Z, Kim AY, Xing Y, Schneidewind A, Madey MA, Fleckenstein JF, Park VM, Galagan JE, Nusbaum C, Walker BD, Lake-Bakaar GV, Daar ES, Jacobson IM, Gomperts ED, Edlin BR, Donfield SM, Chung RT, Talal AH, Marion T, Birren BW, Henn MR, Allen TM.

Hepatology. 2008 Dec;48(6):1769-78. doi: 10.1002/hep.22549.

22.

Potency and mass of factor VIII in FVIII products.

Butenas S, Parhami-Seren B, Gissel MT, Gomperts ED, Fass DN, Mann KG.

Haemophilia. 2009 Jan;15(1):63-72. doi: 10.1111/j.1365-2516.2008.01826.x. Epub 2008 Aug 6.

23.

From theory to practice: applying current clinical knowledge and treatment strategies to the care of hemophilia a patients with inhibitors.

Gomperts ED, Astermark J, Gringeri A, Teitel J.

Blood Rev. 2008 Feb;22 Suppl 1:S1-11. doi: 10.1016/S0268-960X(08)70001-8. Review.

PMID:
18485996
24.

Platelet count is associated with plasma HIV type 1 RNA and disease progression.

Rieg G, Yeaman M, Lail AE, Donfield SM, Gomperts ED, Daar ES; Hemophilia Growth and Development Study (HGDS).

AIDS Res Hum Retroviruses. 2007 Oct;23(10):1257-61.

PMID:
17961113
25.

Delays in maturation among adolescents with hemophilia and a history of inhibitors.

Donfield SM, Lynn HS, Lail AE, Hoots WK, Berntorp E, Gomperts ED; Hemophilia Growth and Development Study Group.

Blood. 2007 Nov 15;110(10):3656-61. Epub 2007 Aug 22.

26.

Baseline HIV type 1 coreceptor tropism predicts disease progression.

Daar ES, Kesler KL, Petropoulos CJ, Huang W, Bates M, Lail AE, Coakley EP, Gomperts ED, Donfield SM; Hemophilia Growth and Development Study.

Clin Infect Dis. 2007 Sep 1;45(5):643-9. Epub 2007 Jul 20. Erratum in: Clin Infect Dis. 2007 Dec 15;45(12):1656.

PMID:
17683002
27.

Long-term major joint outcomes in young adults with haemophilia: interim data from the HGDS.

Su Y, Wong WY, Lail A, Donfield SM, Konzal S, Gomperts E; Hemophilia Growth And Development Study.

Haemophilia. 2007 Jul;13(4):387-90.

PMID:
17610553
28.

A systematic approach to controlling problem bleeds in patients with severe congenital haemophilia A and high-titre inhibitors.

Teitel J, Berntorp E, Collins P, D'Oiron R, Ewenstein B, Gomperts E, Goudemand J, Gringeri A, Key N, Leissinger C, Monahan P, Young G.

Haemophilia. 2007 May;13(3):256-63.

PMID:
17498074
29.

The parachute must be properly folded ...

Donfield SM, Shapiro AD, Gomperts ED, Lynn HS, Usner DW.

J Thromb Haemost. 2007 Mar;5(3):646-7. Epub 2006 Nov 9. No abstract available.

30.
31.

Resistance of porcine circovirus and chicken anemia virus to virus inactivation procedures used for blood products.

Welch J, Bienek C, Gomperts E, Simmonds P.

Transfusion. 2006 Nov;46(11):1951-8.

PMID:
17076851
32.

Hepatitis C virus infection and neurocognitive function.

Soogoor M, Lynn HS, Donfield SM, Gomperts E, Bell TS, Daar ES; Hemophilia Growth and Development Study.

Neurology. 2006 Oct 24;67(8):1482-5.

PMID:
17060580
33.

The next generation of hemophilia treatment specialists.

Berntorp E, Gomperts E, Hoots K, Wong WY.

Semin Thromb Hemost. 2006 Jun;32 Suppl 2:39-42. Review.

PMID:
16804835
34.
35.

Haemophilia Inhibitor Genetics Study - evaluation of a model for studies of complex diseases using linkage and association methods.

Berntorp E, Astermark J, Donfield SM, Nelson GW, Oldenburg J, Shapiro AD, Dimichele DM, Ewenstein BM, Gomperts ED, Winkler CA; Hemophilia Inhibitor Genetics Study.

Haemophilia. 2005 Jul;11(4):427-9. No abstract available.

PMID:
16011603
36.

Haemophilia-related morbidity and quality-of-life.

Donfield SM, Shapiro AD, Gomperts ED, Lynn HS.

Haemophilia. 2005 Jul;11(4):418. No abstract available.

PMID:
16011599
37.

Longitudinal analysis of CD8 T-cell responses to HIV and hepatitis C virus in a cohort of co-infected haemophiliacs.

Harcourt GC, Donfield S, Gomperts E, Daar ES, Goulder P Jr, Phillips RE, Klenerman P; Hemophilia Growth and Development Study (HGDS).

AIDS. 2005 Jul 22;19(11):1135-43.

PMID:
15990566
38.

HIV-1 pol replication capacity predicts disease progression.

Daar ES, Kesler KL, Wrin T, Petropoulo CJ, Bates M, Lail A, Hellmann NS, Gomperts E, Donfield S; Hemophilia Growth and Development Study.

AIDS. 2005 Jun 10;19(9):871-7.

PMID:
15905667
39.
40.

Hemophilia therapy innovation: development of an advanced category recombinant factor VIII by a plasma/albumin-free method. Proceedings of a Special Symposium at the XIXth Congress of the International Society on Thrombosis and Haemostasis, July 12-18, 2003, Birmingham, UK.

Ewenstein BM, Collins P, Tarantino MD, Negrier C, Blanchette V, Shapiro AD, Baker D, Spotts G, Sensel M, Yi SE, Gomperts ED.

Semin Hematol. 2004 Jan;41(1 Suppl 2):1-16; discussion 16-8.

PMID:
15071785
41.

Frequency and causes of hospitalization in HIV-negative children and adolescents with haemophilia A or B and its effect on academic achievement.

Wong WY, Donfield SM, Rains E, FitzGerald G, Pearson SK, Gomperts ED; Hemophilia Growth and Development Study.

Haemophilia. 2004 Jan;10(1):27-33.

PMID:
14962217
42.

Haplotype diversity in the interleukin-4 gene is not associated with HIV-1 transmission and AIDS progression.

Modi WS, O'Brien TR, Vlahov D, Buchbinder S, Gomperts E, Phair J, O'Brien SJ, Winkler C.

Immunogenetics. 2003 Jun;55(3):157-164. doi: 10.1007/s00251-003-0541-5. Epub 2003 Apr 25.

PMID:
12715242
43.

Rapid infusion of intravenous immunoglobulin in patients with neuromuscular diseases.

Gomperts ED, Darr F.

Neurology. 2002 May 14;58(9):1444. No abstract available.

PMID:
12011310
44.

Antibodies to heterologous proteins in hemophilia A patients receiving recombinant factor VIII (Recombinate).

Ingerslev J, Christiansen K, Ravn HB, Bray GL, Gomperts ED; Recombinate Study Group.

Thromb Haemost. 2002 Apr;87(4):626-34.

PMID:
12008945
45.

Safety of factor VIII inhibitor bypass activity (FEIBA): 10-year compilation of thrombotic adverse events.

Ehrlich HJ, Henzl MJ, Gomperts ED.

Haemophilia. 2002 Mar;8(2):83-90.

PMID:
11952842
46.

Defining the impact of hemophilia: the Academic Achievement in Children with Hemophilia Study.

Shapiro AD, Donfield SM, Lynn HS, Cool VA, Stehbens JA, Hunsberger SL, Tonetta S, Gomperts ED; Academic Achievement in Children with Hemophilia Study Group.

Pediatrics. 2001 Dec;108(6):E105.

PMID:
11731632
47.

Relation between HIV-1 and hepatitis C viral load in patients with hemophilia.

Daar ES, Lynn H, Donfield S, Gomperts E, Hilgartner MW, Hoots WK, Chernoff D, Arkin S, Wong WY, Winkler CA; Hemophilia Growth and Development Study.

J Acquir Immune Defic Syndr. 2001 Apr 15;26(5):466-72.

PMID:
11391167
48.

The effect of plasma human immunodeficiency virus RNA and CD4(+) T lymphocytes on growth measurements of hemophilic boys and adolescents.

Hilgartner MW, Donfield SM, Lynn HS, Hoots WK, Gomperts ED, Daar ES, Chernoff D, Pearson SK; Hemophilia Growth and Development Study.

Pediatrics. 2001 Apr;107(4):E56.

PMID:
11335777
49.

A multicenter clinical trial to evaluate the topical hemostatic efficacy of fibrin sealant in burn patients.

Nervi C, Gamelli RL, Greenhalgh DG, Luterman A, Hansbrough JF, Achauer BM, Gomperts ED, Lee M, Navalta L, Cruciani TR.

J Burn Care Rehabil. 2001 Mar-Apr;22(2):99-103.

PMID:
11302613
50.

Hepatitis C virus load is associated with human immunodeficiency virus type 1 disease progression in hemophiliacs.

Daar ES, Lynn H, Donfield S, Gomperts E, O'Brien SJ, Hilgartner MW, Hoots WK, Chernoff D, Arkin S, Wong WY, Winkler CA; Hemophilia Growth and Development Study.

J Infect Dis. 2001 Feb 15;183(4):589-95. Epub 2001 Jan 12.

PMID:
11170984

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