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Items: 40


Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies.

Balanis NG, Sheu KM, Esedebe FN, Patel SJ, Smith BA, Park JW, Alhani S, Gomperts BN, Huang J, Witte ON, Graeber TG.

Cancer Cell. 2019 Jul 8;36(1):17-34.e7. doi: 10.1016/j.ccell.2019.06.005.


Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization.

Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS.

Stem Cell Res Ther. 2019 Feb 12;10(1):52. doi: 10.1186/s13287-019-1147-7.


Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling.

Wilkinson DC, Mellody M, Meneses LK, Hope AC, Dunn B, Gomperts BN.

Curr Protoc Stem Cell Biol. 2018 Aug;46(1):e56. doi: 10.1002/cpsc.56. Epub 2018 Jun 7.


Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells.

Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, Minna JD, Hong LS, Fishbein MC, Dubinett SM.

Cancer Res. 2018 Apr 15;78(8):1986-1999. doi: 10.1158/0008-5472.CAN-17-0315. Epub 2018 Feb 5.


Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization.

Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS.

Stem Cell Res Ther. 2017 Oct 2;8(1):217. doi: 10.1186/s13287-017-0652-9. Erratum in: Stem Cell Res Ther. 2019 Feb 12;10(1):52.


The aCCR(2)ual of M2 Macrophages Provides Some Breathing Room.

Vijayaraj P, Gomperts BN.

Cell Stem Cell. 2017 Jul 6;21(1):1-3. doi: 10.1016/j.stem.2017.06.006. Review.


Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling.

Wilkinson DC, Alva-Ornelas JA, Sucre JM, Vijayaraj P, Durra A, Richardson W, Jonas SJ, Paul MK, Karumbayaram S, Dunn B, Gomperts BN.

Stem Cells Transl Med. 2017 Feb;6(2):622-633. doi: 10.5966/sctm.2016-0192. Epub 2016 Sep 15.


Posttranslational modification of β-catenin is associated with pathogenic fibroblastic changes in bronchopulmonary dysplasia.

Sucre JM, Vijayaraj P, Aros CJ, Wilkinson D, Paul M, Dunn B, Guttentag SH, Gomperts BN.

Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L186-L195. doi: 10.1152/ajplung.00477.2016. Epub 2016 Dec 9.


A three-dimensional human model of the fibroblast activation that accompanies bronchopulmonary dysplasia identifies Notch-mediated pathophysiology.

Sucre JM, Wilkinson D, Vijayaraj P, Paul M, Dunn B, Alva-Ornelas JA, Gomperts BN.

Am J Physiol Lung Cell Mol Physiol. 2016 May 15;310(10):L889-98. doi: 10.1152/ajplung.00446.2015. Epub 2016 Mar 11.


Molecular Pathways: Targeting Cellular Energy Metabolism in Cancer via Inhibition of SLC2A1 and LDHA.

Ooi AT, Gomperts BN.

Clin Cancer Res. 2015 Jun 1;21(11):2440-4. doi: 10.1158/1078-0432.CCR-14-1209. Epub 2015 Apr 2.


Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling.

Paul MK, Bisht B, Darmawan DO, Chiou R, Ha VL, Wallace WD, Chon AT, Hegab AE, Grogan T, Elashoff DA, Alva-Ornelas JA, Gomperts BN.

Cell Stem Cell. 2014 Aug 7;15(2):199-214. doi: 10.1016/j.stem.2014.05.009. Epub 2014 Jun 19.


Induction of multiciliated cells from induced pluripotent stem cells.

Gomperts BN.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6120-1. doi: 10.1073/pnas.1404414111. Epub 2014 Apr 16. No abstract available.


Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis.

Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN.

Cancer Prev Res (Phila). 2014 May;7(5):487-95. doi: 10.1158/1940-6207.CAPR-13-0372. Epub 2014 Mar 11.


Aldehyde dehydrogenase activity enriches for proximal airway basal stem cells and promotes their proliferation.

Hegab AE, Ha VL, Bisht B, Darmawan DO, Ooi AT, Zhang KX, Paul MK, Kim YS, Gilbert JL, Attiga YS, Alva-Ornelas JA, Nickerson DW, Gomperts BN.

Stem Cells Dev. 2014 Mar 15;23(6):664-75. doi: 10.1089/scd.2013.0295. Epub 2014 Jan 2.


MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis.

Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, Gomperts BN, Dubinett SM, Hayden P, Belinsky SA, Lenburg ME, Spira A.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18946-51. doi: 10.1073/pnas.1220319110. Epub 2013 Oct 24.


Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer.

Gomperts BN, Walser TC, Spira A, Dubinett SM.

Cancer Prev Res (Phila). 2013 Jan;6(1):4-7. doi: 10.1158/1940-6207.CAPR-12-0470. Epub 2012 Dec 11.


Isolation and in vitro characterization of basal and submucosal gland duct stem/progenitor cells from human proximal airways.

Hegab AE, Ha VL, Darmawan DO, Gilbert JL, Ooi AT, Attiga YS, Bisht B, Nickerson DW, Gomperts BN.

Stem Cells Transl Med. 2012 Oct;1(10):719-24. doi: 10.5966/sctm.2012-0056. Epub 2012 Sep 27.


Isolation of basal cells and submucosal gland duct cells from mouse trachea.

Hegab AE, Ha VL, Attiga YS, Nickerson DW, Gomperts BN.

J Vis Exp. 2012 Sep 14;(67):e3731. doi: 10.3791/3731.


Repair and regeneration of tracheal surface epithelium and submucosal glands in a mouse model of hypoxic-ischemic injury.

Hegab AE, Nickerson DW, Ha VL, Darmawan DO, Gomperts BN.

Respirology. 2012 Oct;17(7):1101-13. doi: 10.1111/j.1440-1843.2012.02204.x.


Identification of an interleukin 13-induced epigenetic signature in allergic airway inflammation.

Ooi AT, Ram S, Kuo A, Gilbert JL, Yan W, Pellegrini M, Nickerson DW, Chatila TA, Gomperts BN.

Am J Transl Res. 2012;4(2):219-28. Epub 2012 Apr 10.


Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential.

Hegab AE, Ha VL, Gilbert JL, Zhang KX, Malkoski SP, Chon AT, Darmawan DO, Bisht B, Ooi AT, Pellegrini M, Nickerson DW, Gomperts BN.

Stem Cells. 2011 Aug;29(8):1283-93. doi: 10.1002/stem.680.


Evolving concepts in lung carcinogenesis.

Gomperts BN, Spira A, Massion PP, Walser TC, Wistuba II, Minna JD, Dubinett SM.

Semin Respir Crit Care Med. 2011 Feb;32(1):32-43. doi: 10.1055/s-0031-1272867. Epub 2011 Apr 15. Review.


B-acute lymphoblastic leukemia and cystinuria in a patient with duplication 22q11.21 detected by chromosomal microarray analysis.

Chang VY, Quintero-Rivera F, Baldwin EE, Woo K, Martinez-Agosto JA, Fu C, Gomperts BN.

Pediatr Blood Cancer. 2011 Mar;56(3):470-3. doi: 10.1002/pbc.22909. Epub 2010 Nov 28.


Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.

Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, Walser TC, Wallace WD, Dubinett SM, Goodglick L, Gomperts BN.

Cancer Res. 2010 Aug 15;70(16):6639-48. doi: 10.1158/0008-5472.CAN-10-0455.


Lung cancer biomarkers: FISHing in the sputum for risk assessment and early detection.

Gomperts BN, Spira A, Elashoff DE, Dubinett SM.

Cancer Prev Res (Phila). 2010 Apr;3(4):420-3. doi: 10.1158/1940-6207.CAPR-10-0052. Epub 2010 Mar 23. Review.


Quantification of cytokeratin 5 mRNA expression in the circulation of healthy human subjects and after lung transplantation.

Nickerson DW, Presson AP, Weigt SS, Gregson AL, Belperio JA, Gomperts BN.

PLoS One. 2009 Jun 16;4(6):e5925. doi: 10.1371/journal.pone.0005925.


Altered levels of CC chemokines during pulmonary CMV predict BOS and mortality post-lung transplantation.

Weigt SS, Elashoff RM, Keane MP, Strieter RM, Gomperts BN, Xue YY, Ardehali A, Gregson AL, Kubak B, Fishbein MC, Saggar R, Ross DJ, Lynch JP 3rd, Zisman DA, Belperio JA.

Am J Transplant. 2008 Jul;8(7):1512-22. doi: 10.1111/j.1600-6143.2008.02280.x.


Circulating progenitor cells in chronic lung disease.

Mehrad B, Keane MP, Gomperts BN, Strieter RM.

Expert Rev Respir Med. 2007 Aug;1(1):157-65. doi: 10.1586/17476348.1.1.157.


Fibrocytes in lung disease.

Gomperts BN, Strieter RM.

J Leukoc Biol. 2007 Sep;82(3):449-56. Epub 2007 Jun 5. Review.


IL-13 regulates cilia loss and foxj1 expression in human airway epithelium.

Gomperts BN, Kim LJ, Flaherty SA, Hackett BP.

Am J Respir Cell Mol Biol. 2007 Sep;37(3):339-46. Epub 2007 May 31.


The role of CXC chemokines in pulmonary fibrosis.

Strieter RM, Gomperts BN, Keane MP.

J Clin Invest. 2007 Mar;117(3):549-56. Review.


Keratinocyte growth factor improves repair in the injured tracheal epithelium.

Gomperts BN, Belperio JA, Fishbein MC, Keane MP, Burdick MD, Strieter RM.

Am J Respir Cell Mol Biol. 2007 Jul;37(1):48-56. Epub 2007 Mar 1.


IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome.

Keane MP, Gomperts BN, Weigt S, Xue YY, Burdick MD, Nakamura H, Zisman DA, Ardehali A, Saggar R, Lynch JP 3rd, Hogaboam C, Kunkel SL, Lukacs NW, Ross DJ, Grusby MJ, Strieter RM, Belperio JA.

J Immunol. 2007 Jan 1;178(1):511-9.


Stem cells and chronic lung disease.

Gomperts BN, Strieter RM.

Annu Rev Med. 2007;58:285-98. Review.


Chemokine-directed metastasis.

Gomperts BN, Strieter RM.

Contrib Microbiol. 2006;13:170-190. doi: 10.1159/000092972. Review.


Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury.

Gomperts BN, Belperio JA, Rao PN, Randell SH, Fishbein MC, Burdick MD, Strieter RM.

J Immunol. 2006 Feb 1;176(3):1916-27.


CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury.

Belperio JA, Keane MP, Burdick MD, Gomperts BN, Xue YY, Hong K, Mestas J, Zisman D, Ardehali A, Saggar R, Lynch JP 3rd, Ross DJ, Strieter RM.

J Immunol. 2005 Nov 15;175(10):6931-9.


CXC chemokines in angiogenesis.

Strieter RM, Burdick MD, Gomperts BN, Belperio JA, Keane MP.

Cytokine Growth Factor Rev. 2005 Dec;16(6):593-609. Epub 2005 Jul 19. Review.


Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells.

Gomperts BN, Gong-Cooper X, Hackett BP.

J Cell Sci. 2004 Mar 15;117(Pt 8):1329-37. Epub 2004 Mar 2.


Gonococcal hand abscess.

Gomperts BN, White LK.

Pediatr Infect Dis J. 2000 Jul;19(7):671-2. No abstract available.


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