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Items: 27

1.

The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53.

Madan E, Parker TM, Bauer MR, Dhiman A, Pelham CJ, Nagane M, Kuppusamy ML, Holmes M, Holmes TR, Shaik K, Shee K, Kiparoidze S, Smith SD, Park YA, Gomm JJ, Jones LJ, Tomás AR, Cunha AC, Selvendiran K, Hansen LA, Fersht AR, Hideg K, Gogna R, Kuppusamy P.

J Biol Chem. 2018 Mar 23;293(12):4262-4276. doi: 10.1074/jbc.RA117.000950. Epub 2018 Jan 30.

2.

Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors.

Saunderson EA, Stepper P, Gomm JJ, Hoa L, Morgan A, Allen MD, Jones JL, Gribben JG, Jurkowski TP, Ficz G.

Nat Commun. 2017 Nov 13;8(1):1450. doi: 10.1038/s41467-017-01078-2.

3.

A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer.

Carter EP, Gopsill JA, Gomm JJ, Jones JL, Grose RP.

Breast Cancer Res. 2017 Apr 21;19(1):50. doi: 10.1186/s13058-017-0843-4.

4.

Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor-Positive Breast Cancer.

Patel H, Abduljabbar R, Lai CF, Periyasamy M, Harrod A, Gemma C, Steel JH, Patel N, Busonero C, Jerjees D, Remenyi J, Smith S, Gomm JJ, Magnani L, Győrffy B, Jones LJ, Fuller-Pace F, Shousha S, Buluwela L, Rakha EA, Ellis IO, Coombes RC, Ali S.

Clin Cancer Res. 2016 Dec 1;22(23):5929-5938. Epub 2016 Jun 14.

5.

Rigidity sensing and adaptation through regulation of integrin types.

Elosegui-Artola A, Bazellières E, Allen MD, Andreu I, Oria R, Sunyer R, Gomm JJ, Marshall JF, Jones JL, Trepat X, Roca-Cusachs P.

Nat Mater. 2014 Jun;13(6):631-7. doi: 10.1038/nmat3960. Epub 2014 May 4.

6.

Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence.

Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA, Dickinson S, Edwards DR, Pennington CJ, Sestak I, Cuzick J, Marshall JF, Hart IR, Jones JL.

Clin Cancer Res. 2014 Jan 15;20(2):344-57. doi: 10.1158/1078-0432.CCR-13-1504. Epub 2013 Oct 22.

7.

Fibroblast growth factor 7, secreted by breast fibroblasts, is an interleukin-1beta-induced paracrine growth factor for human breast cells.

Palmieri C, Roberts-Clark D, Assadi-Sabet A, Coope RC, O'Hare M, Sunters A, Hanby A, Slade MJ, Gomm JJ, Lam EW, Coombes RC.

J Endocrinol. 2003 Apr;177(1):65-81.

PMID:
12697038
8.

Fibroblast growth factor 8 is expressed at higher levels in lactating human breast and in breast cancer.

Zammit C, Coope R, Gomm JJ, Shousha S, Johnston CL, Coombes RC.

Br J Cancer. 2002 Apr 8;86(7):1097-103.

9.
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The human mammary gland basement membrane is integral to the polarity of luminal epithelial cells.

Slade MJ, Coope RC, Gomm JJ, Coombes RC.

Exp Cell Res. 1999 Feb 25;247(1):267-78.

PMID:
10047469
11.

Increased expression of fibroblast growth factor 8 in human breast cancer.

Marsh SK, Bansal GS, Zammit C, Barnard R, Coope R, Roberts-Clarke D, Gomm JJ, Coombes RC, Johnston CL.

Oncogene. 1999 Jan 28;18(4):1053-60.

12.

A paracrine role for myoepithelial cell-derived FGF2 in the normal human breast.

Gomm JJ, Browne PJ, Coope RC, Bansal GS, Yiangou C, Johnston CL, Mason R, Coombes RC.

Exp Cell Res. 1997 Jul 10;234(1):165-73.

PMID:
9223382
14.

Down-regulation of a novel form of fibroblast growth factor receptor 1 in human breast cancer.

Yiangou C, Cox H, Bansal GS, Coope R, Gomm JJ, Barnard R, Walters J, Groome N, Shousha S, Coombes RC, Johnston CL.

Br J Cancer. 1997;76(11):1419-27.

15.

The location of acidic fibroblast growth factor in the breast is dependent on the activity of proteases present in breast cancer tissue.

Coope RC, Browne PJ, Yiangou C, Bansal GS, Walters J, Groome N, Shousha S, Johnston CL, Coombes RC, Gomm JJ.

Br J Cancer. 1997;75(11):1621-30.

16.

Expression of keratinocyte growth factor and its receptor in human breast cancer.

Bansal GS, Cox HC, Marsh S, Gomm JJ, Yiangou C, Luqmani Y, Coombes RC, Johnston CL.

Br J Cancer. 1997;75(11):1567-74.

17.

Presence of exon 5-deleted oestrogen receptor in human breast cancer: functional analysis and clinical significance.

Desai AJ, Luqmani YA, Walters JE, Coope RC, Dagg B, Gomm JJ, Pace PE, Rees CN, Thirunavukkarasu V, Shousha S, Groome NP, Coombes R, Ali S.

Br J Cancer. 1997;75(8):1173-84.

18.

Fibroblast growth factor 2 in breast cancer: occurrence and prognostic significance.

Yiangou C, Gomm JJ, Coope RC, Law M, Luqmani YA, Shousha S, Coombes RC, Johnston CL.

Br J Cancer. 1997;75(1):28-33.

19.

Inhibitory effects of activin on the growth and morpholgenesis of primary and transformed mammary epithelial cells.

Liu QY, Niranjan B, Gomes P, Gomm JJ, Davies D, Coombes RC, Buluwela L.

Cancer Res. 1996 Mar 1;56(5):1155-63.

20.
21.

Expression of fibroblast growth factor 1 is lower in breast cancer than in the normal human breast.

Bansal GS, Yiangou C, Coope RC, Gomm JJ, Luqmani YA, Coombes RC, Johnston CL.

Br J Cancer. 1995 Dec;72(6):1420-6.

22.

Isolation of pure populations of epithelial and myoepithelial cells from the normal human mammary gland using immunomagnetic separation with Dynabeads.

Gomm JJ, Browne PJ, Coope RC, Liu QY, Buluwela L, Coombes RC.

Anal Biochem. 1995 Mar 20;226(1):91-9.

PMID:
7785785
23.
24.

Effectiveness of combined limonene and 4-hydroxyandrostenedione in the treatment of NMU-induced rat mammary tumours.

Chander SK, Lansdown AG, Luqmani YA, Gomm JJ, Coope RC, Gould N, Coombes RC.

Br J Cancer. 1994 May;69(5):879-82.

25.

Localization of basic fibroblast growth factor and transforming growth factor beta 1 in the human mammary gland.

Gomm JJ, Smith J, Ryall GK, Baillie R, Turnbull L, Coombes RC.

Cancer Res. 1991 Sep 1;51(17):4685-92.

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