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Items: 31


Vti1b promotes TRPV1 sensitization during inflammatory pain.

Sondermann JR, Barry AM, Jahn O, Michel N, Abdelaziz R, Kügler S, Gomez-Varela D, Schmidt M.

Pain. 2019 Feb;160(2):508-527. doi: 10.1097/j.pain.0000000000001418.


Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord.

Barry AM, Sondermann JR, Sondermann JH, Gomez-Varela D, Schmidt M.

Front Mol Neurosci. 2018 Aug 14;11:259. doi: 10.3389/fnmol.2018.00259. eCollection 2018.


Proteome-based systems biology in chronic pain.

Gomez-Varela D, Barry AM, Schmidt M.

J Proteomics. 2019 Jan 6;190:1-11. doi: 10.1016/j.jprot.2018.04.004. Epub 2018 Apr 10.


Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons.

Narayanan P, Hütte M, Kudryasheva G, Taberner FJ, Lechner SG, Rehfeldt F, Gomez-Varela D, Schmidt M.

Elife. 2018 Mar 9;7. pii: e32346. doi: 10.7554/eLife.32346.


Optimization of Experimental Parameters in Data-Independent Mass Spectrometry Significantly Increases Depth and Reproducibility of Results.

Bruderer R, Bernhardt OM, Gandhi T, Xuan Y, Sondermann J, Schmidt M, Gomez-Varela D, Reiter L.

Mol Cell Proteomics. 2017 Dec;16(12):2296-2309. doi: 10.1074/mcp.RA117.000314. Epub 2017 Oct 25.


WITHDRAWN: Heralds of parallel MS: Data-independent acquisition surpassing sequential identification of data dependent acquisition in proteomics.

Bruderer R, Bernhardt OM, Gandhi T, Xuan Y, Sondermann J, Schmidt M, Gomez-Varela D, Reiter L.

Mol Cell Proteomics. 2017 Apr 20. pii: mcp.M116.065730. doi: 10.1074/mcp.M116.065730. [Epub ahead of print]


New targeted approaches for the quantification of data-independent acquisition mass spectrometry.

Bruderer R, Sondermann J, Tsou CC, Barrantes-Freer A, Stadelmann C, Nesvizhskii AI, Schmidt M, Reiter L, Gomez-Varela D.

Proteomics. 2017 May;17(9). doi: 10.1002/pmic.201700021.


Exploring novel paths towards protein signatures of chronic pain.

Gomez-Varela D, Schmidt M.

Mol Pain. 2016 Dec 5;12. pii: 1744806916679658. Print 2016.


Nocistatin sensitizes TRPA1 channels in peripheral sensory neurons.

Avenali L, Abate Fulas O, Sondermann J, Narayanan P, Gomez-Varela D, Schmidt M.

Channels (Austin). 2017 Jan 2;11(1):11-19. doi: 10.1080/19336950.2016.1207025. Epub 2016 Jun 30.


Native Piezo2 Interactomics Identifies Pericentrin as a Novel Regulator of Piezo2 in Somatosensory Neurons.

Narayanan P, Sondermann J, Rouwette T, Karaca S, Urlaub H, Mitkovski M, Gomez-Varela D, Schmidt M.

J Proteome Res. 2016 Aug 5;15(8):2676-87. doi: 10.1021/acs.jproteome.6b00235. Epub 2016 Jul 11.


Standardized Profiling of The Membrane-Enriched Proteome of Mouse Dorsal Root Ganglia (DRG) Provides Novel Insights Into Chronic Pain.

Rouwette T, Sondermann J, Avenali L, Gomez-Varela D, Schmidt M.

Mol Cell Proteomics. 2016 Jun;15(6):2152-68. doi: 10.1074/mcp.M116.058966. Epub 2016 Apr 21.


Modulation of nociceptive ion channels and receptors via protein-protein interactions: implications for pain relief.

Rouwette T, Avenali L, Sondermann J, Narayanan P, Gomez-Varela D, Schmidt M.

Channels (Austin). 2015;9(4):175-85. doi: 10.1080/19336950.2015.1051270. Epub 2015 Jun 3. Review.


Annexin A2 regulates TRPA1-dependent nociception.

Avenali L, Narayanan P, Rouwette T, Cervellini I, Sereda M, Gomez-Varela D, Schmidt M.

J Neurosci. 2014 Oct 29;34(44):14506-16. doi: 10.1523/JNEUROSCI.1801-14.2014.


A novel mechanism for nicotinic potentiation of glutamatergic synapses.

Halff AW, Gómez-Varela D, John D, Berg DK.

J Neurosci. 2014 Feb 5;34(6):2051-64. doi: 10.1523/JNEUROSCI.2795-13.2014.


Lateral mobility of presynaptic α7-containing nicotinic receptors and its relevance for glutamate release.

Gomez-Varela D, Berg DK.

J Neurosci. 2013 Oct 23;33(43):17062-71. doi: 10.1523/JNEUROSCI.1482-13.2013.


PMCA2 via PSD-95 controls calcium signaling by α7-containing nicotinic acetylcholine receptors on aspiny interneurons.

Gómez-Varela D, Schmidt M, Schoellerman J, Peters EC, Berg DK.

J Neurosci. 2012 May 16;32(20):6894-905. doi: 10.1523/JNEUROSCI.5972-11.2012.


Approaches targeting K(V)10.1 open a novel window for cancer diagnosis and therapy.

Pardo LA, Gómez-Varela D, Major F, Sansuk K, Leurs R, Downie BR, Tietze LF, Stühmer W.

Curr Med Chem. 2012;19(5):675-82. Review.


Lateral mobility of nicotinic acetylcholine receptors on neurons is determined by receptor composition, local domain, and cell type.

Fernandes CC, Berg DK, Gómez-Varela D.

J Neurosci. 2010 Jun 30;30(26):8841-51. doi: 10.1523/JNEUROSCI.6236-09.2010.


Characterization of Eag1 channel lateral mobility in rat hippocampal cultures by single-particle-tracking with quantum dots.

Gómez-Varela D, Kohl T, Schmidt M, Rubio ME, Kawabe H, Nehring RB, Schäfer S, Stühmer W, Pardo LA.

PLoS One. 2010 Jan 25;5(1):e8858. doi: 10.1371/journal.pone.0008858.


Postsynaptic scaffolds for nicotinic receptors on neurons.

Neff RA 3rd, Gomez-Varela D, Fernandes CC, Berg DK.

Acta Pharmacol Sin. 2009 Jun;30(6):694-701. doi: 10.1038/aps.2009.52. Epub 2009 May 11. Review.


Participation of HERG channel cytoplasmic structures on regulation by the G protein-coupled TRH receptor.

Alonso-Ron C, Barros F, Manso DG, Gómez-Varela D, Miranda P, Carretero L, Domínguez P, de la Peña P.

Pflugers Arch. 2009 Apr;457(6):1237-52. doi: 10.1007/s00424-008-0599-x. Epub 2008 Nov 6.


Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity.

Gómez-Varela D, Zwick-Wallasch E, Knötgen H, Sánchez A, Hettmann T, Ossipov D, Weseloh R, Contreras-Jurado C, Rothe M, Stühmer W, Pardo LA.

Cancer Res. 2007 Aug 1;67(15):7343-9.


Different relevance of inactivation and F468 residue in the mechanisms of hEag1 channel blockage by astemizole, imipramine and dofetilide.

Gómez-Varela D, Contreras-Jurado C, Furini S, García-Ferreiro R, Stühmer W, Pardo LA.

FEBS Lett. 2006 Sep 18;580(21):5059-66. Epub 2006 Aug 28.


Specificity of TRH receptor coupling to G-proteins for regulation of ERG K+ channels in GH3 rat anterior pituitary cells.

Miranda P, Giráldez T, de la Peña P, Manso DG, Alonso-Ron C, Gómez-Varela D, Domínguez P, Barros F.

J Physiol. 2005 Aug 1;566(Pt 3):717-36. Epub 2005 May 19.


Role of BK potassium channels shaping action potentials and the associated [Ca(2+)](i) oscillations in GH(3) rat anterior pituitary cells.

Miranda P, de la Peña P, Gómez-Varela D, Barros F.

Neuroendocrinology. 2003 Mar;77(3):162-76.


Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells.

Gomez-Varela D, Giraldez T, de la Pena P, Dupuy SG, Garcia-Manso D, Barros F.

J Physiol. 2003 Mar 15;547(Pt 3):913-29. Epub 2003 Jan 17.


Relevance of the proximal domain in the amino-terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor.

Gómez-Varela D, Barros F, Viloria CG, Giráldez T, Manso DG, Dupuy SG, Miranda P, de la Peña P.

FEBS Lett. 2003 Jan 30;535(1-3):125-30.


Influence of amino-terminal structures on kinetic transitions between several closed and open states in human erg K+ channels.

Gómez-Varela D, de la Peña P, García J, Giráldez T, Barros F.

J Membr Biol. 2002 May 15;187(2):117-33.


Correlation between electrical activity and intracellular Ca2+ oscillations in GH3 rat anterior pituitary cells.

Giráldez T, de la Peña P, Gómez-Varela D, Barros F.

Cell Calcium. 2002 Feb;31(2):65-78.


Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating.

Viloria CG, Barros F, Giráldez T, Gómez-Varela D, de la Peña P.

Biophys J. 2000 Jul;79(1):231-46.


Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C.

Barros F, Gomez-Varela D, Viloria CG, Palomero T, Giráldez T, de la Peña P.

J Physiol. 1998 Sep 1;511 ( Pt 2):333-46.

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