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Items: 1 to 50 of 106

1.

Novel signaling aspects of ceramide 1-phosphate.

Presa N, Gomez-Larrauri A, Dominguez-Herrera A, Trueba M, Gomez-Muñoz A.

Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Apr;1865(4):158630. doi: 10.1016/j.bbalip.2020.158630. Epub 2020 Jan 17. Review.

PMID:
31958571
2.

PGC1α Suppresses Prostate Cancer Cell Invasion through ERRα Transcriptional Control.

Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigué A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardón C, Fernández-Ruiz S, Rodriguez-Hernandez I, Hermanova I, Astobiza I, Cortazar AR, Corres-Mendizabal J, Gomez-Muñoz A, Sanz-Moreno V, Torrano V, Carracedo A.

Cancer Res. 2019 Dec 15;79(24):6153-6165. doi: 10.1158/0008-5472.CAN-19-1231. Epub 2019 Oct 8.

3.

Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice.

Presa N, Clugston RD, Lingrell S, Kelly SE, Merrill AH Jr, Jana S, Kassiri Z, Gómez-Muñoz A, Vance DE, Jacobs RL, van der Veen JN.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):14-25. doi: 10.1016/j.bbadis.2018.10.010. Epub 2018 Oct 6.

4.

Regulation of adipogenesis by ceramide 1-phosphate.

Ordoñez M, Presa N, Dominguez-Herrera A, Trueba M, Gomez-Muñoz A.

Exp Cell Res. 2018 Nov 15;372(2):150-157. doi: 10.1016/j.yexcr.2018.09.021. Epub 2018 Sep 27.

PMID:
30267661
5.

CANCERTOOL: A Visualization and Representation Interface to Exploit Cancer Datasets.

Cortazar AR, Torrano V, Martín-Martín N, Caro-Maldonado A, Camacho L, Hermanova I, Guruceaga E, Lorenzo-Martín LF, Caloto R, Gomis RR, Apaolaza I, Quesada V, Trka J, Gomez-Muñoz A, Vincent S, Bustelo XR, Planes FJ, Aransay AM, Carracedo A.

Cancer Res. 2018 Nov 1;78(21):6320-6328. doi: 10.1158/0008-5472.CAN-18-1669. Epub 2018 Sep 19.

6.

The Role of Ceramide 1-Phosphate in Tumor Cell Survival and Dissemination.

Gomez-Muñoz A.

Adv Cancer Res. 2018;140:217-234. doi: 10.1016/bs.acr.2018.04.012. Epub 2018 May 24. Review.

PMID:
30060810
7.

Ceramide-1-phosphate has protective properties against cyclophosphamide-induced ovarian damage in a mice model of premature ovarian failure.

Pascuali N, Scotti L, Di Pietro M, Oubiña G, Bas D, May M, Gómez Muñoz A, Cuasnicú PS, Cohen DJ, Tesone M, Abramovich D, Parborell F.

Hum Reprod. 2018 May 1;33(5):844-859. doi: 10.1093/humrep/dey045.

PMID:
29534229
8.

Low-dose statin treatment increases prostate cancer aggressiveness.

Caro-Maldonado A, Camacho L, Zabala-Letona A, Torrano V, Fernández-Ruiz S, Zamacola-Bascaran K, Arreal L, Valcárcel-Jiménez L, Martín-Martín N, Flores JM, Cortazar AR, Zúñiga-García P, Arruabarrena-Aristorena A, Guillaumond F, Cabrera D, Falcón-Perez JM, Aransay AM, Gomez-Muñoz A, Olivan M, Morote J, Carracedo A.

Oncotarget. 2017 Oct 31;9(2):1494-1504. doi: 10.18632/oncotarget.22217. eCollection 2018 Jan 5.

9.

Lysophosphatidic Acid Signaling Axis Mediates Ceramide 1-Phosphate-Induced Proliferation of C2C12 Myoblasts.

Bernacchioni C, Cencetti F, Ouro A, Bruno M, Gomez-Muñoz A, Donati C, Bruni P.

Int J Mol Sci. 2018 Jan 4;19(1). pii: E139. doi: 10.3390/ijms19010139.

10.

PPARδ Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth.

Martín-Martín N, Zabala-Letona A, Fernández-Ruiz S, Arreal L, Camacho L, Castillo-Martin M, Cortazar AR, Torrano V, Astobiza I, Zúñiga-García P, Ugalde-Olano A, Loizaga-Iriarte A, Unda M, Valcárcel-Jiménez L, Arruabarrena-Aristorena A, Piva M, Sánchez-Mosquera P, Aransay AM, Gomez-Muñoz A, Barrio R, Sutherland JD, Carracedo A.

Cancer Res. 2018 Jan 15;78(2):399-409. doi: 10.1158/0008-5472.CAN-17-0908. Epub 2017 Nov 29.

11.

Vascular endothelial growth factor mediates ceramide 1-phosphate-stimulated macrophage proliferation.

Ouro A, Arana L, Riazy M, Zhang P, Gomez-Larrauri A, Steinbrecher U, Duronio V, Gomez-Muñoz A.

Exp Cell Res. 2017 Dec 15;361(2):277-283. doi: 10.1016/j.yexcr.2017.10.027. Epub 2017 Oct 31.

PMID:
29080796
12.

Implication of Ceramide Kinase in Adipogenesis.

Ordoñez M, Presa N, Trueba M, Gomez-Muñoz A.

Mediators Inflamm. 2017;2017:9374563. doi: 10.1155/2017/9374563. Epub 2017 Jul 20.

13.

Excess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed Rats.

Kelly KB, Kennelly JP, Ordonez M, Nelson R, Leonard K, Stabler S, Gomez-Muñoz A, Field CJ, Jacobs RL.

Nutrients. 2016 Sep 23;8(10). pii: E594. doi: 10.3390/nu8100594.

14.

Implication of matrix metalloproteinases 2 and 9 in ceramide 1-phosphate-stimulated macrophage migration.

Ordoñez M, Rivera IG, Presa N, Gomez-Muñoz A.

Cell Signal. 2016 Aug;28(8):1066-74. doi: 10.1016/j.cellsig.2016.05.005. Epub 2016 May 6.

PMID:
27164414
15.

Regulation of cell migration and inflammation by ceramide 1-phosphate.

Presa N, Gomez-Larrauri A, Rivera IG, Ordoñez M, Trueba M, Gomez-Muñoz A.

Biochim Biophys Acta. 2016 May;1861(5):402-9. doi: 10.1016/j.bbalip.2016.02.007. Epub 2016 Feb 11. Review.

PMID:
26875839
16.

Potential of ceramide 1-phosphate as a novel therapeutic agent in pulmonary inflammation.

Gomez-Larrauri A, Trueba M, Gomez-Muñoz A.

Expert Rev Clin Pharmacol. 2016;9(5):629-31. doi: 10.1586/17512433.2016.1152181. Epub 2016 Feb 24. No abstract available.

PMID:
26855208
17.

C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-κB Activation in Neutrophils.

Baudiß K, de Paula Vieira R, Cicko S, Ayata K, Hossfeld M, Ehrat N, Gómez-Muñoz A, Eltzschig HK, Idzko M.

J Immunol. 2016 Mar 1;196(5):2319-26. doi: 10.4049/jimmunol.1402681. Epub 2016 Jan 22.

18.

Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells.

Rivera IG, Ordoñez M, Presa N, Gangoiti P, Gomez-Larrauri A, Trueba M, Fox T, Kester M, Gomez-Muñoz A.

Biochem Pharmacol. 2016 Feb 15;102:107-119. doi: 10.1016/j.bcp.2015.12.009. Epub 2015 Dec 18.

PMID:
26707801
19.

Control of inflammatory responses by ceramide, sphingosine 1-phosphate and ceramide 1-phosphate.

Gomez-Muñoz A, Presa N, Gomez-Larrauri A, Rivera IG, Trueba M, Ordoñez M.

Prog Lipid Res. 2016 Jan;61:51-62. doi: 10.1016/j.plipres.2015.09.002. Epub 2015 Dec 15. Review.

PMID:
26703189
20.

Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors.

Katz S, Ernst O, Avni D, Athamna M, Philosoph A, Arana L, Ouro A, Hoeferlin LA, Meijler MM, Chalfant CE, Gómez-Muñoz A, Zor T.

Immunol Lett. 2016 Jan;169:73-81. doi: 10.1016/j.imlet.2015.12.001. Epub 2015 Dec 3.

21.

Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis.

Wang SW, Hojabrpour P, Zhang P, Kolesnick RN, Steinbrecher UP, Gómez-Muñoz A, Duronio V.

Biochim Biophys Acta. 2015 Nov;1851(11):1482-9. doi: 10.1016/j.bbalip.2015.08.002. Epub 2015 Aug 4.

22.

Caged ceramide 1-phosphate (C1P) analogs: Novel tools for studying C1P biology.

Gomez-Muñoz A, Gangoiti P, Rivera IG, Presa N, Gomez-Larrauri A, Ordoñez M.

Chem Phys Lipids. 2016 Jan;194:79-84. doi: 10.1016/j.chemphyslip.2015.07.019. Epub 2015 Jul 29. Review.

PMID:
26232662
23.

Sphingomyelinase D/ceramide 1-phosphate in cell survival and inflammation.

Rivera IG, Ordoñez M, Presa N, Gomez-Larrauri A, Simón J, Trueba M, Gomez-Muñoz A.

Toxins (Basel). 2015 Apr 29;7(5):1457-66. doi: 10.3390/toxins7051457. Review.

24.

Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation.

Baudiß K, Ayata CK, Lazar Z, Cicko S, Beckert J, Meyer A, Zech A, Vieira RP, Bittman R, Gómez-Muñoz A, Merfort I, Idzko M.

Eur Respir J. 2015 Jun;45(6):1669-80. doi: 10.1183/09031936.00080014. Epub 2015 Jan 22.

25.

Decreased lipogenesis in white adipose tissue contributes to the resistance to high fat diet-induced obesity in phosphatidylethanolamine N-methyltransferase-deficient mice.

Gao X, van der Veen JN, Hermansson M, Ordoñez M, Gomez-Muñoz A, Vance DE, Jacobs RL.

Biochim Biophys Acta. 2015 Feb;1851(2):152-62. doi: 10.1016/j.bbalip.2014.11.006. Epub 2014 Nov 15.

PMID:
25463480
26.

Phosphatidic acid inhibits ceramide 1-phosphate-stimulated macrophage migration.

Ouro A, Arana L, Rivera IG, Ordoñez M, Gomez-Larrauri A, Presa N, Simón J, Trueba M, Gangoiti P, Bittman R, Gomez-Muñoz A.

Biochem Pharmacol. 2014 Dec 15;92(4):642-50. doi: 10.1016/j.bcp.2014.10.005. Epub 2014 Oct 18.

PMID:
25450673
27.

Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice.

Gao X, van der Veen JN, Zhu L, Chaba T, Ordoñez M, Lingrell S, Koonen DP, Dyck JR, Gomez-Muñoz A, Vance DE, Jacobs RL.

J Hepatol. 2015 Apr;62(4):913-20. doi: 10.1016/j.jhep.2014.11.026. Epub 2014 Nov 27.

PMID:
25433161
28.

Ceramide 1-phosphate induces macrophage chemoattractant protein-1 release: involvement in ceramide 1-phosphate-stimulated cell migration.

Arana L, Ordoñez M, Ouro A, Rivera IG, Gangoiti P, Trueba M, Gomez-Muñoz A.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1213-26. doi: 10.1152/ajpendo.00480.2012. Epub 2013 Apr 2.

29.

New insights on the role of ceramide 1-phosphate in inflammation.

Gomez-Muñoz A, Gangoiti P, Arana L, Ouro A, Rivera IG, Ordoñez M, Trueba M.

Biochim Biophys Acta. 2013 Jun;1831(6):1060-6. doi: 10.1016/j.bbalip.2013.02.001. Epub 2013 Feb 11. Review.

PMID:
23410840
30.

Ceramide 1-phosphate stimulates glucose uptake in macrophages.

Ouro A, Arana L, Gangoiti P, Rivera IG, Ordoñez M, Trueba M, Lankalapalli RS, Bittman R, Gomez-Muñoz A.

Cell Signal. 2013 Apr;25(4):786-95. doi: 10.1016/j.cellsig.2013.01.009. Epub 2013 Jan 16.

31.

New signalling pathway involved in the anti-proliferative action of vitamin D₃ and its analogues in human neuroblastoma cells. A role for ceramide kinase.

Bini F, Frati A, Garcia-Gil M, Battistini C, Granado M, Martinesi M, Mainardi M, Vannini E, Luzzati F, Caleo M, Peretto P, Gomez-Muñoz A, Meacci E.

Neuropharmacology. 2012 Sep;63(4):524-37. doi: 10.1016/j.neuropharm.2012.04.026. Epub 2012 May 8.

PMID:
22579669
32.

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

Arana L, Gangoiti P, Ouro A, Rivera IG, Ordoñez M, Trueba M, Lankalapalli RS, Bittman R, Gomez-Muñoz A.

Exp Cell Res. 2012 Feb 15;318(4):350-60. doi: 10.1016/j.yexcr.2011.11.013. Epub 2011 Dec 6.

PMID:
22155727
33.

Ceramide 1-phosphate stimulates proliferation of C2C12 myoblasts.

Gangoiti P, Bernacchioni C, Donati C, Cencetti F, Ouro A, Gómez-Muñoz A, Bruni P.

Biochimie. 2012 Mar;94(3):597-607. doi: 10.1016/j.biochi.2011.09.009. Epub 2011 Sep 17.

34.

Misalignments in the retinal nerve fiber layer evaluation using cirrus high-definition optical coherence tomography.

Moreno-Montañés J, Antón A, Olmo N, Bonet E, Alvarez A, Barrio-Barrio J, García-Granero M, Gómez-Muñoz A.

J Glaucoma. 2011 Dec;20(9):559-65. doi: 10.1097/IJG.0b013e3181fa0def.

PMID:
21336154
35.

Ceramide-1-phosphate in cell survival and inflammatory signaling.

Gómez-Muñoz A, Gangoiti P, Granado MH, Arana L, Ouro A.

Adv Exp Med Biol. 2010;688:118-30. Review.

PMID:
20919650
36.

Activation of mTOR and RhoA is a major mechanism by which Ceramide 1-phosphate stimulates macrophage proliferation.

Gangoiti P, Arana L, Ouro A, Granado MH, Trueba M, Gómez-Muñoz A.

Cell Signal. 2011 Jan;23(1):27-34. doi: 10.1016/j.cellsig.2010.08.001. Epub 2010 Aug 18.

PMID:
20727406
37.

Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease.

Gangoiti P, Camacho L, Arana L, Ouro A, Granado MH, Brizuela L, Casas J, Fabriás G, Abad JL, Delgado A, Gómez-Muñoz A.

Prog Lipid Res. 2010 Oct;49(4):316-34. doi: 10.1016/j.plipres.2010.02.004. Epub 2010 Mar 1. Review.

PMID:
20193711
38.

Ceramide and ceramide 1-phosphate in health and disease.

Arana L, Gangoiti P, Ouro A, Trueba M, Gómez-Muñoz A.

Lipids Health Dis. 2010 Feb 5;9:15. doi: 10.1186/1476-511X-9-15. Review.

39.

Activation of protein kinase C-alpha is essential for stimulation of cell proliferation by ceramide 1-phosphate.

Gangoiti P, Granado MH, Arana L, Ouro A, Gomez-Muñoz A.

FEBS Lett. 2010 Feb 5;584(3):517-24. doi: 10.1016/j.febslet.2009.11.086. Epub 2009 Nov 27.

40.

Caged ceramide 1-phosphate analogues: synthesis and properties.

Lankalapalli RS, Ouro A, Arana L, Gómez-Muñoz A, Bittman R.

J Org Chem. 2009 Nov 20;74(22):8844-7. doi: 10.1021/jo902076w.

41.

Distinct receptor-mediated activities in macrophages for natural ceramide-1-phosphate (C1P) and for phospho-ceramide analogue-1 (PCERA-1).

Levi M, Meijler MM, Gómez-Muñoz A, Zor T.

Mol Cell Endocrinol. 2010 Jan 27;314(2):248-55. doi: 10.1016/j.mce.2009.05.007. Epub 2009 May 23. Review.

PMID:
19467294
42.

Ceramide 1-phosphate inhibits serine palmitoyltransferase and blocks apoptosis in alveolar macrophages.

Granado MH, Gangoiti P, Ouro A, Arana L, Gómez-Muñoz A.

Biochim Biophys Acta. 2009 Apr;1791(4):263-72. doi: 10.1016/j.bbalip.2009.01.023. Epub 2009 Feb 7.

PMID:
19416641
43.

Chain length specificity for activation of cPLA2alpha by C1P: use of the dodecane delivery system to determine lipid-specific effects.

Wijesinghe DS, Subramanian P, Lamour NF, Gentile LB, Granado MH, Bielawska A, Szulc Z, Gomez-Munoz A, Chalfant CE.

J Lipid Res. 2009 Oct;50(10):1986-95. doi: 10.1194/jlr.M800367-JLR200. Epub 2008 Dec 15.

44.

Ceramide 1-phosphate (C1P) promotes cell migration Involvement of a specific C1P receptor.

Granado MH, Gangoiti P, Ouro A, Arana L, González M, Trueba M, Gómez-Muñoz A.

Cell Signal. 2009 Mar;21(3):405-12. doi: 10.1016/j.cellsig.2008.11.003. Epub 2008 Nov 12.

PMID:
19041940
45.

Involvement of nitric oxide in the promotion of cell survival by ceramide 1-phosphate.

Gangoiti P, Granado MH, Arana L, Ouro A, Gómez-Muñoz A.

FEBS Lett. 2008 Jun 25;582(15):2263-9. doi: 10.1016/j.febslet.2008.05.027. Epub 2008 May 27.

46.

Ceramide 1-phosphate stimulates macrophage proliferation through activation of the PI3-kinase/PKB, JNK and ERK1/2 pathways.

Gangoiti P, Granado MH, Wang SW, Kong JY, Steinbrecher UP, Gómez-Muñoz A.

Cell Signal. 2008 Apr;20(4):726-36. doi: 10.1016/j.cellsig.2007.12.008. Epub 2007 Dec 17.

PMID:
18234473
47.

Implication of ceramide, ceramide 1-phosphate and sphingosine 1-phosphate in tumorigenesis.

Gangoiti P, Granado MH, Alonso A, Goñi FM, Gómez-Muñoz A.

Transl Oncogenomics. 2008 Apr 10;3:81-98.

48.

Ceramide kinase and ceramide-1-phosphate.

Wijesinghe DS, Lamour NF, Gomez-Munoz A, Chalfant CE.

Methods Enzymol. 2007;434:265-92.

PMID:
17954253
49.

Membrane regulation of the stress response from prokaryotic models to mammalian cells.

Vigh L, Nakamoto H, Landry J, Gomez-Munoz A, Harwood JL, Horvath I.

Ann N Y Acad Sci. 2007 Oct;1113:40-51. Epub 2007 Jul 26. Review.

PMID:
17656573
50.

Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways.

Brizuela L, Rábano M, Gangoiti P, Narbona N, Macarulla JM, Trueba M, Gómez-Muñoz A.

J Lipid Res. 2007 Oct;48(10):2264-74. Epub 2007 Jul 3.

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