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Items: 28


Targeting Palbociclib-Resistant Estrogen Receptor-Positive Breast Cancer Cells via Oncolytic Virotherapy.

Lypova N, Lanceta L, Gibson A, Vega S, Garza-Morales R, McMasters KM, Chesney J, Gomez-Gutierrez JG, Imbert-Fernandez Y.

Cancers (Basel). 2019 May 16;11(5). pii: E684. doi: 10.3390/cancers11050684.


A Novel Form of 4-1BBL Prevents Cancer Development via Nonspecific Activation of CD4+ T and Natural Killer Cells.

Barsoumian HB, Batra L, Shrestha P, Bowen WS, Zhao H, Egilmez NK, Gomez-Gutierrez JG, Yolcu ES, Shirwan H.

Cancer Res. 2019 Feb 15;79(4):783-794. doi: 10.1158/0008-5472.CAN-18-2401.


A DNA Vaccine Encoding SA-4-1BBL Fused to HPV-16 E7 Antigen Has Prophylactic and Therapeutic Efficacy in a Cervical Cancer Mouse Model.

Garza-Morales R, Perez-Trujillo JJ, Martinez-Jaramillo E, Saucedo-Cardenas O, Loera-Arias MJ, Garcia-Garcia A, Rodriguez-Rocha H, Yolcu E, Shirwan H, Gomez-Gutierrez JG, Montes-de-Oca-Luna R.

Cancers (Basel). 2019 Jan 15;11(1). pii: E96. doi: 10.3390/cancers11010096.


The role of JNK phosphorylation as a molecular target to enhance adenovirus replication, oncolysis and cancer therapeutic efficacy.

Wechman SL, Rao XM, Gomez-Gutierrez JG, Zhou HS, McMasters KM.

Cancer Biol Ther. 2018;19(12):1174-1184. doi: 10.1080/15384047.2018.1491503. Epub 2018 Aug 1.


Temozolomide Enhances Triple-Negative Breast Cancer Virotherapy In Vitro.

Garza-Morales R, Gonzalez-Ramos R, Chiba A, Montes de Oca-Luna R, McNally LR, McMasters KM, Gomez-Gutierrez JG.

Cancers (Basel). 2018 May 17;10(5). pii: E144. doi: 10.3390/cancers10050144.


Adenovirus Lacking E1b Efficiently Induces Cytopathic Effect in HPV-16-Positive Murine Cancer Cells via Virus Replication and Apoptosis.

Martinez-Jaramillo E, Garza-Morales R, Wechman SL, Montes de Oca-Luna R, Saucedo-Cardenas O, Shirwan H, Yolcu E, McMasters KM, Gomez-Gutierrez JG.

Cancer Invest. 2018 Jan 2;36(1):19-27. doi: 10.1080/07357907.2018.1430812. Epub 2018 Feb 1.


Temozolomide renders murine cancer cells susceptible to oncolytic adenovirus replication and oncolysis.

Garza-Morales R, Yaddanapudi K, Perez-Hernandez R, Riedinger E, McMasters KM, Shirwan H, Yolcu E, Montes de Oca-Luna R, Gomez-Gutierrez JG.

Cancer Biol Ther. 2018 Mar 4;19(3):188-197. doi: 10.1080/15384047.2017.1416274. Epub 2018 Jan 22.


Development of Lactococcus lactis encoding fluorescent proteins, GFP, mCherry and iRFP regulated by the nisin-controlled gene expression system.

Martinez-Jaramillo E, Garza-Morales R, Loera-Arias MJ, Saucedo-Cardenas O, Montes-de-Oca-Luna R, McNally LR, Gomez-Gutierrez JG.

Biotech Histochem. 2017;92(3):167-174. doi: 10.1080/10520295.2017.1289554. Epub 2017 Mar 20.


Development of an Oncolytic Adenovirus with Enhanced Spread Ability through Repeated UV Irradiation and Cancer Selection.

Wechman SL, Rao XM, Cheng PH, Gomez-Gutierrez JG, McMasters KM, Zhou HS.

Viruses. 2016 Jun 14;8(6). pii: E167. doi: 10.3390/v8060167.


A spontaneous metastasis model reveals the significance of claudin-9 overexpression in lung cancer metastasis.

Sharma RK, Chheda ZS, Das Purkayastha BP, Gomez-Gutierrez JG, Jala VR, Haribabu B.

Clin Exp Metastasis. 2016 Mar;33(3):263-75. doi: 10.1007/s10585-015-9776-4. Epub 2015 Dec 15.


Tumor specific liposomes improve detection of pancreatic adenocarcinoma in vivo using optoacoustic tomography.

Yin W, Kimbrough CW, Gomez-Gutierrez JG, Burns CT, Chuong P, Grizzle WE, McNally LR.

J Nanobiotechnology. 2015 Dec 1;13:90. doi: 10.1186/s12951-015-0139-8.


Combined therapy of oncolytic adenovirus and temozolomide enhances lung cancer virotherapy in vitro and in vivo.

Gomez-Gutierrez JG, Nitz J, Sharma R, Wechman SL, Riedinger E, Martinez-Jaramillo E, Sam Zhou H, McMasters KM.

Virology. 2016 Jan;487:249-59. doi: 10.1016/j.virol.2015.10.019. Epub 2015 Nov 9.


Adenovirus-mediated FKHRL1/TM sensitizes melanoma cells to apoptosis induced by temozolomide.

Egger ME, McNally LR, Nitz J, McMasters KM, Gomez-Gutierrez JG.

Hum Gene Ther Clin Dev. 2014 Sep;25(3):186-95. doi: 10.1089/humc.2014.022.


Enhancement of Ad-CRT/E7-mediated antitumor effect by preimmunization with L. lactis expressing HPV-16 E7.

Rangel-Colmenero BR, Gomez-Gutierrez JG, Villatoro-Hernández J, Zavala-Flores LM, Quistián-Martínez D, Rojas-Martínez A, Arce-Mendoza AY, Guzmán-López S, Montes-de-Oca-Luna R, Saucedo-Cárdenas O.

Viral Immunol. 2014 Nov;27(9):463-7. doi: 10.1089/vim.2014.0055. Epub 2014 Sep 12.


Adenovirus-mediated FKHRL1/TM sensitizes melanoma cells to apoptosis induced by temozolomide.

Egger M, McNally L, Nitz J, McMasters KM, Gomez-Gutierrez JG.

Hum Gene Ther Clin Dev. 2014 Aug 20. [Epub ahead of print]


Enhanced cancer cell killing by truncated E2F-1 used in combination with oncolytic adenovirus.

Gomez-Gutierrez JG, Rao XM, Zhou HS, McMasters KM.

Virology. 2012 Nov 25;433(2):538-47. doi: 10.1016/j.virol.2012.09.003. Epub 2012 Sep 27.


Adenovirus-mediated expression of mutated forkhead human transcription like-1 suppresses tumor growth in a mouse melanoma xenograft model.

Gomez-Gutierrez JG, Egger ME, Hao H, Zhou HS, McMasters KM.

Cancer Biol Ther. 2012 Oct;13(12):1195-204. doi: 10.4161/cbt.21349. Epub 2012 Aug 15.


E2F-1 lacking the transcriptional activity domain induces autophagy.

Garcia-Garcia A, Rodriguez-Rocha H, Tseng MT, Montes de Oca-Luna R, Zhou HS, McMasters KM, Gomez-Gutierrez JG.

Cancer Biol Ther. 2012 Sep;13(11):1091-101. doi: 10.4161/cbt.21143. Epub 2012 Jul 24.


Adenoviruses induce autophagy to promote virus replication and oncolysis.

Rodriguez-Rocha H, Gomez-Gutierrez JG, Garcia-Garcia A, Rao XM, Chen L, McMasters KM, Zhou HS.

Virology. 2011 Jul 20;416(1-2):9-15. doi: 10.1016/j.virol.2011.04.017. Epub 2011 May 14.


E2F-1- and E2Ftr-mediated apoptosis: the role of DREAM and HRK.

Hao H, Chen C, Rao XM, Gomez-Gutierrez JG, Zhou HS, McMasters KM.

J Cell Mol Med. 2012 Mar;16(3):605-15. doi: 10.1111/j.1582-4934.2011.01338.x.


Adenovirus-mediated expression of truncated E2F-1 suppresses tumor growth in vitro and in vivo.

Gomez-Gutierrez JG, Garcia-Garcia A, Hao H, Rao XM, Montes de Oca-Luna R, Zhou HS, McMasters KM.

Cancer. 2010 Sep 15;116(18):4420-32. doi: 10.1002/cncr.25322.


Developing adenoviral vectors encoding therapeutic genes toxic to host cells: comparing binary and single-inducible vectors expressing truncated E2F-1.

Gomez-Gutierrez JG, Rao XM, Garcia-Garcia A, Hao H, McMasters KM, Zhou HS.

Virology. 2010 Feb 20;397(2):337-45. doi: 10.1016/j.virol.2009.11.021. Epub 2009 Dec 8.


Secretion of biologically active interferon-gamma inducible protein-10 (IP-10) by Lactococcus lactis.

Villatoro-Hernandez J, Loera-Arias MJ, Gamez-Escobedo A, Franco-Molina M, Gomez-Gutierrez JG, Rodriguez-Rocha H, Gutierrez-Puente Y, Saucedo-Cardenas O, Valdes-Flores J, Montes-de-Oca-Luna R.

Microb Cell Fact. 2008 Jul 28;7:22. doi: 10.1186/1475-2859-7-22.


Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication.

Zheng X, Rao XM, Gomez-Gutierrez JG, Hao H, McMasters KM, Zhou HS.

J Virol. 2008 Apr;82(7):3415-27. doi: 10.1128/JVI.01708-07. Epub 2008 Jan 30.


Induction of apoptosis signal-regulating Kinase 1 by E2F-1 may not be essential for E2F-1-mediated apoptosis in melanoma cells.

Dong YB, Phelps AM, Yang HL, Jamshidi-Parsian A, Chen C, Hao H, Gomez-Gutierrez JG, Zhou HS, McMasters KM.

Tumour Biol. 2007;28(2):111-22. Epub 2007 Feb 8.


E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation.

Hao H, Dong Y, Bowling MT, Gomez-Gutierrez JG, Zhou HS, McMasters KM.

BMC Cancer. 2007 Jan 30;7:24.


Vaccination with an adenoviral vector expressing calreticulin-human papillomavirus 16 E7 fusion protein eradicates E7 expressing established tumors in mice.

Gomez-Gutierrez JG, Elpek KG, Montes de Oca-Luna R, Shirwan H, Sam Zhou H, McMasters KM.

Cancer Immunol Immunother. 2007 Jul;56(7):997-1007. Epub 2006 Dec 5.


Adenovirus-mediated gene transfer of FKHRL1 triple mutant efficiently induces apoptosis in melanoma cells.

Gomez-Gutierrez JG, Souza V, Hao HY, Montes de Oca-Luna R, Dong YB, Zhou HS, McMasters KM.

Cancer Biol Ther. 2006 Jul;5(7):875-83. Epub 2006 Jul 20.


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