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Items: 21

1.

Heterologous Expression of a Cryptic Gene Cluster from Streptomyces leeuwenhoekii C34T Yields a Novel Lasso Peptide, Leepeptin.

Gomez-Escribano JP, Castro JF, Razmilic V, Jarmusch SA, Saalbach G, Ebel R, Jaspars M, Andrews B, Asenjo JA, Bibb MJ.

Appl Environ Microbiol. 2019 Nov 14;85(23). pii: e01752-19. doi: 10.1128/AEM.01752-19. Print 2019 Dec 1.

2.

Analysis of the Tunicamycin Biosynthetic Gene Cluster of Streptomyces chartreusis Reveals New Insights into Tunicamycin Production and Immunity.

Widdick D, Royer SF, Wang H, Vior NM, Gomez-Escribano JP, Davis BG, Bibb MJ.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00130-18. doi: 10.1128/AAC.00130-18. Print 2018 Aug.

3.

The 'gifted' actinomycete Streptomyces leeuwenhoekii.

Castro JF, Razmilic V, Gomez-Escribano JP, Andrews B, Asenjo J, Bibb M.

Antonie Van Leeuwenhoek. 2018 Aug;111(8):1433-1448. doi: 10.1007/s10482-018-1034-8. Epub 2018 Feb 3. Review.

PMID:
29397490
4.

Discovery of Unusual Biaryl Polyketides by Activation of a Silent Streptomyces venezuelae Biosynthetic Gene Cluster.

Thanapipatsiri A, Gomez-Escribano JP, Song L, Bibb MJ, Al-Bassam M, Chandra G, Thamchaipenet A, Challis GL, Bibb MJ.

Chembiochem. 2016 Nov 17;17(22):2189-2198. doi: 10.1002/cbic.201600396. Epub 2016 Oct 13.

5.

Next Generation Sequencing of Actinobacteria for the Discovery of Novel Natural Products.

Gomez-Escribano JP, Alt S, Bibb MJ.

Mar Drugs. 2016 Apr 13;14(4). pii: E78. doi: 10.3390/md14040078. Review.

6.

A Streptomyces coelicolor host for the heterologous expression of Type III polyketide synthase genes.

Thanapipatsiri A, Claesen J, Gomez-Escribano JP, Bibb M, Thamchaipenet A.

Microb Cell Fact. 2015 Sep 16;14:145. doi: 10.1186/s12934-015-0335-0.

7.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

8.

The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2.

Gomez-Escribano JP, Castro JF, Razmilic V, Chandra G, Andrews B, Asenjo JA, Bibb MJ.

BMC Genomics. 2015 Jun 30;16:485. doi: 10.1186/s12864-015-1652-8.

9.

Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekii.

Castro JF, Razmilic V, Gomez-Escribano JP, Andrews B, Asenjo JA, Bibb MJ.

Appl Environ Microbiol. 2015 Sep 1;81(17):5820-31. doi: 10.1128/AEM.01039-15. Epub 2015 Jun 19.

10.

A relA-dependent regulatory cascade for auto-induction of microbisporicin production in Microbispora corallina.

Fernández-Martínez LT, Gomez-Escribano JP, Bibb MJ.

Mol Microbiol. 2015 Aug;97(3):502-14. doi: 10.1111/mmi.13046. Epub 2015 May 29.

11.

New insights into chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10712.

Fernández-Martínez LT, Borsetto C, Gomez-Escribano JP, Bibb MJ, Al-Bassam MM, Chandra G, Bibb MJ.

Antimicrob Agents Chemother. 2014 Dec;58(12):7441-50. doi: 10.1128/AAC.04272-14. Epub 2014 Sep 29.

12.

Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways.

Gomez-Escribano JP, Bibb MJ.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):425-31. doi: 10.1007/s10295-013-1348-5. Epub 2013 Oct 6. Review.

PMID:
24096958
13.

Streptomyces coelicolor as an expression host for heterologous gene clusters.

Gomez-Escribano JP, Bibb MJ.

Methods Enzymol. 2012;517:279-300. doi: 10.1016/B978-0-12-404634-4.00014-0.

PMID:
23084944
14.

Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediates.

Wyszynski FJ, Lee SS, Yabe T, Wang H, Gomez-Escribano JP, Bibb MJ, Lee SJ, Davies GJ, Davis BG.

Nat Chem. 2012 May 20;4(7):539-46. doi: 10.1038/nchem.1351.

PMID:
22717438
15.

Identification and characterization of CdgB, a diguanylate cyclase involved in developmental processes in Streptomyces coelicolor.

Tran NT, Den Hengst CD, Gomez-Escribano JP, Buttner MJ.

J Bacteriol. 2011 Jun;193(12):3100-8. doi: 10.1128/JB.01460-10. Epub 2011 Apr 22.

16.

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters.

Gomez-Escribano JP, Bibb MJ.

Microb Biotechnol. 2011 Mar;4(2):207-15. doi: 10.1111/j.1751-7915.2010.00219.x. Epub 2010 Oct 26.

17.

Heterologous expression of the biosynthetic gene clusters of coumermycin A(1), clorobiocin and caprazamycins in genetically modified Streptomyces coelicolor strains.

Flinspach K, Westrich L, Kaysser L, Siebenberg S, Gomez-Escribano JP, Bibb M, Gust B, Heide L.

Biopolymers. 2010 Sep;93(9):823-32. doi: 10.1002/bip.21493.

PMID:
20578003
18.

Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2).

Gottelt M, Kol S, Gomez-Escribano JP, Bibb M, Takano E.

Microbiology. 2010 Aug;156(Pt 8):2343-2353. doi: 10.1099/mic.0.038281-0. Epub 2010 May 6.

PMID:
20447997
19.

Regulatory mechanisms controlling antibiotic production in Streptomyces clavuligerus.

Liras P, Gomez-Escribano JP, Santamarta I.

J Ind Microbiol Biotechnol. 2008 Jul;35(7):667-76. doi: 10.1007/s10295-008-0351-8. Epub 2008 Apr 30. Review.

PMID:
18446393
20.

Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp.

Gomez-Escribano JP, Martín JF, Hesketh A, Bibb MJ, Liras P.

Microbiology. 2008 Mar;154(Pt 3):744-755. doi: 10.1099/mic.0.2007/011890-0.

PMID:
18310021

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