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Urinary Renin in Patients and Mice With Diabetic Kidney Disease.

Tang J, Wysocki J, Ye M, Vallés PG, Rein J, Shirazi M, Bader M, Gomez RA, Sequeira-Lopez MS, Afkarian M, Batlle D.

Hypertension. 2019 Jul;74(1):83-94. doi: 10.1161/HYPERTENSIONAHA.119.12873. Epub 2019 May 13.


Leukemia development initiated by deletion of RBP-J: mouse strain, deletion efficiency and cell of origin.

Belyea BC, Xu F, Sequeira-Lopez MLS, Gomez RA.

Dis Model Mech. 2018 Dec 18;11(12). pii: dmm036731. doi: 10.1242/dmm.036731.


Changes in cell fate determine the regenerative and functional capacity of the developing kidney before and after release of obstruction.

Nagalakshmi VK, Li M, Shah S, Gigliotti JC, Klibanov AL, Epstein FH, Chevalier RL, Gomez RA, Sequeira-Lopez MLS.

Clin Sci (Lond). 2018 Dec 5;132(23):2519-2545. doi: 10.1042/CS20180623. Print 2018 Dec 12.


Super-enhancers maintain renin-expressing cell identity and memory to preserve multi-system homeostasis.

Martinez MF, Medrano S, Brown EA, Tufan T, Shang S, Bertoncello N, Guessoum O, Adli M, Belyea BC, Sequeira-Lopez MLS, Gomez RA.

J Clin Invest. 2018 Nov 1;128(11):4787-4803. doi: 10.1172/JCI121361. Epub 2018 Oct 2.


Therapeutic Communities In Latin America: An International Descriptive Study In Different Countries Across Latin America.

Gómez Restrepo C, Maldonado P, Rodríguez N, Ruiz-Gaviria R, Escalante MÁ, Gómez RÁ, Araujo MR, Schmidt de Oliveira AC, Chávez Rivera JS, Godínez García JA, Piazza Ferrand M, Blitchtein Winicki D.

Rev Colomb Psiquiatr. 2018 Jul - Sep;47(3):140-147. doi: 10.1016/j.rcp.2017.01.011. Epub 2017 Apr 28. English, Spanish.


Preserving kidney health during intensive blood pressure control.

Sequeira-Lopez MLS, Gomez RA.

Nat Rev Nephrol. 2018 Sep;14(9):537-538. doi: 10.1038/s41581-018-0034-2. No abstract available.


Safety of multidose immunotherapy vials after routine use.

Nath P, Freiler J, Gomez RA.

J Allergy Clin Immunol Pract. 2018 Nov - Dec;6(6):2110-2111. doi: 10.1016/j.jaip.2018.04.037. Epub 2018 May 9. No abstract available.


Angiotensin II Short-Loop Feedback: Is There a Role of Ang II for the Regulation of the Renin System In Vivo?

Neubauer B, Schrankl J, Steppan D, Neubauer K, Sequeira-Lopez ML, Pan L, Gomez RA, Coffman TM, Gross KW, Kurtz A, Wagner C.

Hypertension. 2018 Jun;71(6):1075-1082. doi: 10.1161/HYPERTENSIONAHA.117.10357. Epub 2018 Apr 16.


Renin cells in homeostasis, regeneration and immune defence mechanisms.

Gomez RA, Sequeira-Lopez MLS.

Nat Rev Nephrol. 2018 Apr;14(4):231-245. doi: 10.1038/nrneph.2017.186. Epub 2018 Jan 30. Review.


Quality measurers of therapeutic communities for substance dependence: an international collaborative study survey in Latin America.

Gómez-Restrepo C, Maldonado P, Rodríguez N, Ruiz-Gaviria R, Escalante MÁ, Gómez RÁ, de Araujo MR, de Oliveira ACS, Rivera JSC, García JAG, Ferrand MP, Blitchtein-Winicki D.

Subst Abuse Treat Prev Policy. 2017 Dec 20;12(1):53. doi: 10.1186/s13011-017-0129-y.


Persistent and inducible neogenesis repopulates progenitor renin lineage cells in the kidney.

Hickmann L, Steglich A, Gerlach M, Al-Mekhlafi M, Sradnick J, Lachmann P, Sequeira-Lopez MLS, Gomez RA, Hohenstein B, Hugo C, Todorov VT.

Kidney Int. 2017 Dec;92(6):1419-1432. doi: 10.1016/j.kint.2017.04.014. Epub 2017 Jul 6.


Chronic Stimulation of Renin Cells Leads to Vascular Pathology.

Oka M, Medrano S, Sequeira-Lόpez MLS, Gómez RA.

Hypertension. 2017 Jul;70(1):119-128. doi: 10.1161/HYPERTENSIONAHA.117.09283. Epub 2017 May 22.


Systemic reactions to immunotherapy during mountain cedar season: implications for seasonal dose adjustment.

Wong PH, Quinn JM, Gomez RA, Webb CN.

J Allergy Clin Immunol Pract. 2017 Sep - Oct;5(5):1438-1439.e1. doi: 10.1016/j.jaip.2017.03.021. Epub 2017 May 9. No abstract available.


Identification of cardiac hemo-vascular precursors and their requirement of sphingosine-1-phosphate receptor 1 for heart development.

Hu Y, Belyea BC, Li M, Göthert JR, Gomez RA, Sequeira-Lopez ML.

Sci Rep. 2017 Mar 24;7:45205. doi: 10.1038/srep45205.


Tracking the stochastic fate of cells of the renin lineage after podocyte depletion using multicolor reporters and intravital imaging.

Kaverina NV, Kadoya H, Eng DG, Rusiniak ME, Sequeira-Lopez ML, Gomez RA, Pippin JW, Gross KW, Peti-Peterdi J, Shankland SJ.

PLoS One. 2017 Mar 22;12(3):e0173891. doi: 10.1371/journal.pone.0173891. eCollection 2017.


Plasticity of Renin Cells in the Kidney Vasculature.

Gomez RA, Lopez ML.

Curr Hypertens Rep. 2017 Feb;19(2):14. doi: 10.1007/s11906-017-0711-8. Review.


Fate of Renin Cells During Development and Disease.

Gomez RA.

Hypertension. 2017 Mar;69(3):387-395. doi: 10.1161/HYPERTENSIONAHA.116.08316. Epub 2017 Jan 30. Review. No abstract available.


Phylogenetic placement of the Pacific Northwest subterranean endemic diving beetle Stygoporus oregonensis Larson & LaBonte (Dytiscidae, Hydroporinae).

Kanda K, Gomez RA, Van Driesche R, Miller KB, Maddison DR.

Zookeys. 2016 Nov 16;(632):75-91. eCollection 2016.


Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression.

Lu KT, Keen HL, Weatherford ET, Sequeira-Lopez ML, Gomez RA, Sigmund CD.

Hypertension. 2016 May;67(5):992-9. doi: 10.1161/HYPERTENSIONAHA.115.07082. Epub 2016 Feb 29.


Up high and down low: Molecular systematics and insight into the diversification of the ground beetle genus Rhadine LeConte.

Gómez RA, Reddell J, Will K, Moore W.

Mol Phylogenet Evol. 2016 May;98:161-75. doi: 10.1016/j.ympev.2016.01.018. Epub 2016 Feb 12.


Novel Functions of Renin Precursors in Homeostasis and Disease.

Gomez RA, Sequeira-Lopez ML.

Physiology (Bethesda). 2016 Jan;31(1):25-33. doi: 10.1152/physiol.00039.2015. Review.


Hemovascular Progenitors in the Kidney Require Sphingosine-1-Phosphate Receptor 1 for Vascular Development.

Hu Y, Li M, Göthert JR, Gomez RA, Sequeira-Lopez ML.

J Am Soc Nephrol. 2016 Jul;27(7):1984-95. doi: 10.1681/ASN.2015060610. Epub 2015 Nov 3.


Vascular versus tubular renin: role in kidney development.

Sequeira-Lopez ML, Nagalakshmi VK, Li M, Sigmund CD, Gomez RA.

Am J Physiol Regul Integr Comp Physiol. 2015 Sep 15;309(6):R650-7. doi: 10.1152/ajpregu.00313.2015. Epub 2015 Aug 5.


Aldo-keto reductase 1b7, a novel marker for renin cells, is regulated by cyclic AMP signaling.

Lin EE, Pentz ES, Sequeira-Lopez ML, Gomez RA.

Am J Physiol Regul Integr Comp Physiol. 2015 Sep;309(5):R576-84. doi: 10.1152/ajpregu.00222.2015. Epub 2015 Jul 15.


Characteristics, Outcomes, and Predictability of Critically Ill Obstetric Patients: A Multicenter Prospective Cohort Study.

Vasquez DN, Das Neves AV, Vidal L, Moseinco M, Lapadula J, Zakalik G, Santa-Maria A, Gomez RA, Capalbo M, Fernandez C, Agüero-Villareal E, Vommaro S, Moretti M, Soli SB, Ballestero F, Sottile JP, Chapier V, Lovesio C, Santos J, Bertoletti F, Intile AD, Desmery PM, Estenssoro E; ProPOC Study Group.

Crit Care Med. 2015 Sep;43(9):1887-97. doi: 10.1097/CCM.0000000000001139.


Clinical and immunologic assessment of a cluster method during allergen immunotherapy refill dosing.

Waibel KH, Owens TJ, Crisp HC, Gomez RA.

J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):793-4. doi: 10.1016/j.jaip.2014.09.003. Epub 2014 Oct 3. No abstract available.


The earliest metanephric arteriolar progenitors and their role in kidney vascular development.

Sequeira-Lopez ML, Lin EE, Li M, Hu Y, Sigmund CD, Gomez RA.

Am J Physiol Regul Integr Comp Physiol. 2015 Jan 15;308(2):R138-49. doi: 10.1152/ajpregu.00428.2014. Epub 2014 Nov 26.


Deletion of the miR-143/145 cluster leads to hydronephrosis in mice.

Medrano S, Sequeira-Lopez ML, Gomez RA.

Am J Pathol. 2014 Dec;184(12):3226-38. doi: 10.1016/j.ajpath.2014.08.012. Epub 2014 Oct 7.


Renin lineage cells repopulate the glomerular mesangium after injury.

Starke C, Betz H, Hickmann L, Lachmann P, Neubauer B, Kopp JB, Sequeira-Lopez ML, Gomez RA, Hohenstein B, Todorov VT, Hugo CP.

J Am Soc Nephrol. 2015 Jan;26(1):48-54. doi: 10.1681/ASN.2014030265. Epub 2014 Jun 5.


Recombination signal binding protein for Ig-κJ region regulates juxtaglomerular cell phenotype by activating the myo-endocrine program and suppressing ectopic gene expression.

Castellanos-Rivera RM, Pentz ES, Lin E, Gross KW, Medrano S, Yu J, Sequeira-Lopez ML, Gomez RA.

J Am Soc Nephrol. 2015 Jan;26(1):67-80. doi: 10.1681/ASN.2013101045. Epub 2014 Jun 5.


Local renal circadian clocks control fluid-electrolyte homeostasis and BP.

Tokonami N, Mordasini D, Pradervand S, Centeno G, Jouffe C, Maillard M, Bonny O, Gachon F, Gomez RA, Sequeira-Lopez ML, Firsov D.

J Am Soc Nephrol. 2014 Jul;25(7):1430-9. doi: 10.1681/ASN.2013060641. Epub 2014 Mar 20.


Identification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia.

Belyea BC, Xu F, Pentz ES, Medrano S, Li M, Hu Y, Turner S, Legallo R, Jones CA, Tario JD, Liang P, Gross KW, Sequeira-Lopez ML, Gomez RA.

Nat Commun. 2014;5:3273. doi: 10.1038/ncomms4273.


Fate and plasticity of renin precursors in development and disease.

Gomez RA, Belyea B, Medrano S, Pentz ES, Sequeira-Lopez ML.

Pediatr Nephrol. 2014 Apr;29(4):721-6. doi: 10.1007/s00467-013-2688-0. Epub 2013 Dec 15. Review.


RBP-J in FOXD1+ renal stromal progenitors is crucial for the proper development and assembly of the kidney vasculature and glomerular mesangial cells.

Lin EE, Sequeira-Lopez ML, Gomez RA.

Am J Physiol Renal Physiol. 2014 Jan;306(2):F249-58. doi: 10.1152/ajprenal.00313.2013. Epub 2013 Nov 13.


Pericytes synthesize renin.

Berg AC, Chernavvsky-Sequeira C, Lindsey J, Gomez RA, Sequeira-Lopez ML.

World J Nephrol. 2013 Feb 6;2(1):11-6. doi: 10.5527/wjn.v2.i1.11.


Two oldies join forces to guard homeostasis.

Gomez RA, Sequeira-Lopez ML.

Am J Physiol Renal Physiol. 2013 Dec 1;305(11):F1546. doi: 10.1152/ajprenal.00496.2013. Epub 2013 Sep 18. No abstract available.


A side-by-side comparison of Rotorod and Burkard pollen and spore collections.

Crisp HC, Gomez RA, White KM, Quinn JM.

Ann Allergy Asthma Immunol. 2013 Aug;111(2):118-25. doi: 10.1016/j.anai.2013.05.021.


Determination of sildenafil by preconcentration on surfactant coated polymeric resin followed by spectrofluorimetry.

Wang CC, Gómez RA, Fernandez LP.

J Pharm Anal. 2013 Jun;3(3):173-179. doi: 10.1016/j.jpha.2012.11.001. Epub 2012 Nov 14.


Novel case of anaphylaxis to sturgeon fish.

Yip SK, Gomez RA, White KM, England RW.

Ann Allergy Asthma Immunol. 2013 Apr;110(4):306-7. doi: 10.1016/j.anai.2013.01.012. Epub 2013 Feb 14. No abstract available.


Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells.

Kurt B, Paliege A, Willam C, Schwarzensteiner I, Schucht K, Neymeyer H, Sequeira-Lopez ML, Bachmann S, Gomez RA, Eckardt KU, Kurtz A.

J Am Soc Nephrol. 2013 Feb;24(3):433-44. doi: 10.1681/ASN.2012080791. Epub 2013 Feb 7.


Hemodynamic and hormonal changes to dual renin-angiotensin system inhibition in experimental hypertension.

Moniwa N, Varagic J, Ahmad S, VonCannon JL, Simington SW, Wang H, Groban L, Brosnihan KB, Nagata S, Kato J, Kitamura K, Gomez RA, Lopez ML, Ferrario CM.

Hypertension. 2013 Feb;61(2):417-24. doi: 10.1161/HYPERTENSIONAHA.112.201889. Epub 2012 Dec 10.


Possible predictors of poor angiogenesis after hematopoietic stem cell autograft for lower limb ischemia.

Gómez RA, Fernández JD, Cabrera M, Marrero I, Ramírez N, Alvarez I.

MEDICC Rev. 2012 Jul;14(3):31-6.


[Preliminary Study on Cognitive Determinants Influencing Argentine Youngsters towards Intensive Alcohol Consumption or Binge Drinking].

Gómez RÁ, Luque LE, Tomas MT, Tort BE, Giménez JA.

Rev Colomb Psiquiatr. 2012 Jun;41(2):309-27. doi: 10.1016/S0034-7450(14)60007-X. Epub 2014 May 10. Spanish.


Histone acetyl transferases CBP and p300 are necessary for maintenance of renin cell identity and transformation of smooth muscle cells to the renin phenotype.

Pentz ES, Cordaillat M, Carretero OA, Tucker AE, Sequeira Lopez ML, Gomez RA.

Am J Physiol Heart Circ Physiol. 2012 Jun 15;302(12):H2545-52. doi: 10.1152/ajpheart.00782.2011. Epub 2012 Apr 20.


Effect of a multistage ultraendurance triathlon on aldosterone, vasopressin, extracellular water and urine electrolytes.

Knechtle B, Morales NP, González ER, Gutierrez AA, Sevilla JN, Gómez RA, Robledo AR, Rodríguez AL, Fraire OS, Andonie JL, Lopez LC, Kohler G, Rosemann T.

Scott Med J. 2012 Feb;57(1):26-32. doi: 10.1258/smj.2011.011287.


Development of the renal arterioles.

Sequeira Lopez ML, Gomez RA.

J Am Soc Nephrol. 2011 Dec;22(12):2156-65. doi: 10.1681/ASN.2011080818. Epub 2011 Nov 3. Review.


Genes that confer the identity of the renin cell.

Brunskill EW, Sequeira-Lopez ML, Pentz ES, Lin E, Yu J, Aronow BJ, Potter SS, Gomez RA.

J Am Soc Nephrol. 2011 Dec;22(12):2213-25. doi: 10.1681/ASN.2011040401. Epub 2011 Oct 27. Erratum in: J Am Soc Nephrol. 2012 Mar;23(3):567.


Two microRNAs, miR-330 and miR-125b-5p, mark the juxtaglomerular cell and balance its smooth muscle phenotype.

Medrano S, Monteagudo MC, Sequeira-Lopez ML, Pentz ES, Gomez RA.

Am J Physiol Renal Physiol. 2012 Jan 1;302(1):F29-37. doi: 10.1152/ajprenal.00460.2011. Epub 2011 Oct 12.

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