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Elevated Neutrophil to Lymphocyte Ratio in Older Adults with Cocaine Use Disorder as a Marker of Chronic Inflammation.

Soder HE, Berumen AM, Gomez KE, Green CE, Suchting R, Wardle MC, Vincent J, Teixeira AL, Schmitz JM, Lane SD.

Clin Psychopharmacol Neurosci. 2020 Feb 29;18(1):32-40. doi: 10.9758/cpn.2020.18.1.32.


Addendum to British Society for Haematology Guidelines on Investigation and Management of Antiphospholipid syndrome, 2012 (Br. J. Haematol. 2012; 157: 47-58): use of direct acting oral anticoagulants.

Arachchillage DRJ, Gomez K, Alikhan R, Anderson JAM, Lester W, Laffan M; British Society for Haematology Haemostasis and Thrombosis Taskforce.

Br J Haematol. 2020 Jan 13. doi: 10.1111/bjh.16308. [Epub ahead of print] No abstract available.


Inhibiting translation elongation with SVC112 suppresses cancer stem cells and inhibits growth in head and neck squamous carcinoma.

Keysar SB, Gomes N, Miller B, Jackson BC, Le PN, Morton JJ, Reisinger J, Chimed TS, Gomez KE, Nieto C, Frederick B, Pronk GJ, Somerset HL, Tan AC, Wang XJ, Raben D, Su TT, Jimeno A.

Cancer Res. 2020 Jan 7. pii: canres.3232.2019. doi: 10.1158/0008-5472.CAN-19-3232. [Epub ahead of print]


Cdk5-Dependent Phosphorylation of CaV3.2 T-Type Channels: Possible Role in Nerve Ligation-Induced Neuropathic Allodynia and the Compound Action Potential in Primary Afferent C Fibers.

Gomez K, Calderón-Rivera A, Sandoval A, González-Ramírez R, Vargas-Parada A, Ojeda-Alonso J, Granados-Soto V, Delgado-Lezama R, Felix R.

J Neurosci. 2020 Jan 8;40(2):283-296. doi: 10.1523/JNEUROSCI.0181-19.2019. Epub 2019 Nov 19.


Evaluation of the biocompatibility of a PVA/SA scaffold with a human gingival fibroblast (HGF) by using electrochemical impedance spectroscopy.

Hernández M, Álvarez-Pérez MA, Genesca J, Gómez KK, Covelo A.

Bioelectrochemistry. 2020 Feb;131:107386. doi: 10.1016/j.bioelechem.2019.107386. Epub 2019 Sep 15.


The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels.

Zhou Y, Cai S, Moutal A, Yu J, Gómez K, Madura CL, Shan Z, Pham NYN, Serafini MJ, Dorame A, Scott DD, François-Moutal L, Perez-Miller S, Patek M, Khanna M, Khanna R.

ACS Chem Neurosci. 2019 Dec 18;10(12):4834-4846. doi: 10.1021/acschemneuro.9b00547. Epub 2019 Nov 21.


Leading edge or tumor core: Intratumor cancer stem cell niches in oral cavity squamous cell carcinoma and their association with stem cell function.

Chowdhury FN, Reisinger J, Gomez KE, Chimed TS, Thomas CM, Le PN, Miller B, Morton JJ, Nieto CM, Somerset HL, Wang XJ, Keysar SB, Jimeno A.

Oral Oncol. 2019 Nov;98:118-124. doi: 10.1016/j.oraloncology.2019.09.011. Epub 2019 Oct 3.


Next-generation sequencing for the diagnosis of MYH9-RD: Predicting pathogenic variants.

Bury L, Megy K, Stephens JC, Grassi L, Greene D, Gleadall N, Althaus K, Allsup D, Bariana TK, Bonduel M, Butta NV, Collins P, Curry N, Deevi SVV, Downes K, Duarte D, Elliott K, Falcinelli E, Furie B, Keeling D, Lambert MP, Linger R, Mangles S, Mapeta R, Millar CM, Penkett C, Perry DJ, Stirrups KE, Turro E, Westbury SK, Wu J, BioResource N, Gomez K, Freson K, Ouwehand WH, Gresele P, Simeoni I.

Hum Mutat. 2020 Jan;41(1):277-290. doi: 10.1002/humu.23927. Epub 2019 Oct 15.


A systematic review exploring how young people use online forums for support around mental health issues.

Hanley T, Prescott J, Gomez KU.

J Ment Health. 2019 Oct;28(5):566-576. doi: 10.1080/09638237.2019.1630725. Epub 2019 Jul 3.


Transcription Factor Sp1 Regulates the Expression of Calcium Channel α2δ-1 Subunit in Neuropathic Pain.

Gómez K, Sandoval A, Barragán-Iglesias P, Granados-Soto V, Delgado-Lezama R, Felix R, González-Ramírez R.

Neuroscience. 2019 Aug 1;412:207-215. doi: 10.1016/j.neuroscience.2019.06.011. Epub 2019 Jun 18.


Germline mutations in the transcription factor IKZF5 cause thrombocytopenia.

Lentaigne C, Greene D, Sivapalaratnam S, Favier R, Seyres D, Thys C, Grassi L, Mangles S, Sibson K, Stubbs M, Burden F, Bordet JC, Armari-Alla C, Erber W, Farrow S, Gleadall N, Gomez K, Megy K, Papadia S, Penkett CJ, Sims MC, Stefanucci L, Stephens JC, Read RJ, Stirrups KE, Ouwehand WH, Laffan MA; NIHR BioResource, Frontini M, Freson K, Turro E.

Blood. 2019 Dec 5;134(23):2070-2081. doi: 10.1182/blood.2019000782.


NICE NG89 recommendations for extended pharmacological thromboprophylaxis - is it justified and is it cost effective: a rebuttal from the British Society for Haematology.

Lester W, Gomez K, Shapiro S, Dabhi K, Laffan M.

Br J Haematol. 2019 Sep;186(5):790-791. doi: 10.1111/bjh.16007. Epub 2019 Jun 5. No abstract available.


Rapid screening fluorescence method applied to detection and quantitation of paralytic shellfish toxins in invertebrate marine vectors.

Masias D, Gómez K, Contreras C, Gaete L, García C.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 Jul;36(7):1118-1137. doi: 10.1080/19440049.2019.1615645. Epub 2019 May 17.


Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders.

Downes K, Megy K, Duarte D, Vries M, Gebhart J, Hofer S, Shamardina O, Deevi SVV, Stephens J, Mapeta R, Tuna S, Al Hasso N, Besser MW, Cooper N, Daugherty L, Gleadall N, Greene D, Haimel M, Martin H, Papadia S, Revel-Vilk S, Sivapalaratnam S, Symington E, Thomas W, Thys C, Tolios A, Penkett CJ; NIHR BioResource, Ouwehand WH, Abbs S, Laffan MA, Turro E, Simeoni I, Mumford AD, Henskens YMC, Pabinger I, Gomez K, Freson K.

Blood. 2019 Dec 5;134(23):2082-2091. doi: 10.1182/blood.2018891192.


Generation of T. cruzi-Specific Primary CD4+ T Cell Lines from Peripheral Blood Mononuclear Cells Isolated from Chagas Disease Patients.

Acevedo GR, Alcaráz PB, Pinilla C, Gómez KA.

Methods Mol Biol. 2019;1955:315-337. doi: 10.1007/978-1-4939-9148-8_24.


New information on rare diseases - how important is that for us?

Gomez K.

Br J Haematol. 2019 Jun;185(5):819-820. doi: 10.1111/bjh.15833. Epub 2019 Mar 11. No abstract available.


Evaluation of von Willebrand factor concentrates by platelet adhesion to collagen using an in vitro flow assay.

Riddell A, Vinayagam S, Gomez K, Laffan M, McKinnon T.

Res Pract Thromb Haemost. 2018 Dec 7;3(1):126-135. doi: 10.1002/rth2.12166. eCollection 2019 Jan.


Improved Nutrition Status in Patients With Advanced Heart Failure Implanted With a Left Ventricular Assist Device.

Genev I, Yost G, Gregory M, Gomez K, Pappas P, Tatooles A, Bhat G.

Nutr Clin Pract. 2019 Jun;34(3):444-449. doi: 10.1002/ncp.10238. Epub 2019 Jan 15.


Directional Selection Rather Than Functional Constraints Can Shape the G Matrix in Rapidly Adapting Asexuals.

Gomez K, Bertram J, Masel J.

Genetics. 2019 Feb;211(2):715-729. doi: 10.1534/genetics.118.301685. Epub 2018 Dec 17.


Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia.

Bariana TK, Labarque V, Heremans J, Thys C, De Reys M, Greene D, Jenkins B, Grassi L, Seyres D, Burden F, Whitehorn D, Shamardina O, Papadia S, Gomez K, BioResource N, Van Geet C, Koulman A, Ouwehand WH, Ghevaert C, Frontini M, Turro E, Freson K.

Haematologica. 2019 May;104(5):1036-1045. doi: 10.3324/haematol.2018.204784. Epub 2018 Nov 22.


Computational enhancement of single-cell sequences for inferring tumor evolution.

Miura S, Huuki LA, Buturla T, Vu T, Gomez K, Kumar S.

Bioinformatics. 2018 Sep 1;34(17):i917-i926. doi: 10.1093/bioinformatics/bty571.


Wnt signaling dynamics in head and neck squamous cell cancer tumor-stroma interactions.

Le PN, Keysar SB, Miller B, Eagles JR, Chimed TS, Reisinger J, Gomez KE, Nieto C, Jackson BC, Somerset HL, Morton JJ, Wang XJ, Jimeno A.

Mol Carcinog. 2019 Mar;58(3):398-410. doi: 10.1002/mc.22937. Epub 2018 Nov 28.


Prevalence and determinants of anal human papillomavirus infection in men who have sex with men and transgender women.

Cranston RD, Carballo-Diéguez A, Gundacker H, Richardson BA, Giguere R, Dolezal C, Siegel A, KunjaraNaAyudhya RP, Gomez K, Piper JM, Lama JR, McGowan I; MTN-017 Protocol Team.

Int J STD AIDS. 2019 Feb;30(2):154-162. doi: 10.1177/0956462418797864. Epub 2018 Oct 18.


Phase 1 Pharmacokinetic Trial of 2 Intravaginal Rings Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048.

Liu AY, Zhang J, Anderson PL, Wagner T, Pan Z, Peda M, Gomez K, Beamer M, Jacobson C, Strizki J, Dezzutti CS, Piper JM; MTN-028 Protocol Team for the Microbicide Trials Network.

Clin Infect Dis. 2019 Mar 19;68(7):1129-1135. doi: 10.1093/cid/ciy652.


Phenotype description and response to thrombopoietin receptor agonist in DIAPH1-related disorder.

Westbury SK, Downes K, Burney C, Lozano ML, Obaji SG, Toh CH, Sevivas T, Morgan NV, Erber WN, Kempster C, Moore SF, Thys C, Papadia S, Ouwehand WH; NIHR BioResource–Rare Diseases, Laffan MA, Gomez K, Freson K, Rivera J, Mumford AD.

Blood Adv. 2018 Sep 25;2(18):2341-2346. doi: 10.1182/bloodadvances.2018020370. No abstract available.


The Unsolved Jigsaw Puzzle of the Immune Response in Chagas Disease.

Acevedo GR, Girard MC, Gómez KA.

Front Immunol. 2018 Aug 24;9:1929. doi: 10.3389/fimmu.2018.01929. eCollection 2018. Review.


Dual use of hematopoietic and mesenchymal stem cells enhances engraftment and immune cell trafficking in an allogeneic humanized mouse model of head and neck cancer.

Morton JJ, Keysar SB, Perrenoud L, Chimed TS, Reisinger J, Jackson B, Le PN, Nieto C, Gomez K, Miller B, Gao D, Somerset H, Wang XJ, Jimeno A.

Mol Carcinog. 2018 Nov;57(11):1651-1663. doi: 10.1002/mc.22887. Epub 2018 Sep 3.


Disturbances of postural sway components in cannabis users.

Bolbecker AR, Apthorp D, Martin AS, Tahayori B, Moravec L, Gomez KL, O'Donnell BF, Newman SD, Hetrick WP.

Drug Alcohol Depend. 2018 Sep 1;190:54-61. doi: 10.1016/j.drugalcdep.2018.05.012. Epub 2018 Jun 21.


Evaluation of the immune response against Trypanosoma cruzi cytosolic tryparedoxin peroxidase in human natural infection.

Girard MC, Acevedo GR, López L, Ossowski MS, Piñeyro MD, Grosso JP, Fernandez M, Hernández Vasquez Y, Robello C, Gómez KA.

Immunology. 2018 Nov;155(3):367-378. doi: 10.1111/imm.12979. Epub 2018 Aug 3.


Inequalities in health? An update on the effect of social deprivation for patients with breast cancer in South East Wales.

Boyce K, White C, Hunt P, Abel N, James Z, Micic T, Gomez KF.

Surgeon. 2019 Apr;17(2):88-96. doi: 10.1016/j.surge.2018.05.004. Epub 2018 Jun 20.


Predicting clone genotypes from tumor bulk sequencing of multiple samples.

Miura S, Gomez K, Murillo O, Huuki LA, Vu T, Buturla T, Kumar S.

Bioinformatics. 2018 Dec 1;34(23):4017-4026. doi: 10.1093/bioinformatics/bty469.


Identification of new risk factors for rolandic epilepsy: CNV at Xp22.31 and alterations at cholinergic synapses.

Addis L, Sproviero W, Thomas SV, Caraballo RH, Newhouse SJ, Gomez K, Hughes E, Kinali M, McCormick D, Hannan S, Cossu S, Taylor J, Akman CI, Wolf SM, Mandelbaum DE, Gupta R, van der Spek RA, Pruna D, Pal DK.

J Med Genet. 2018 Sep;55(9):607-616. doi: 10.1136/jmedgenet-2018-105319. Epub 2018 May 22.


Persistence of bacterial DNA in orthopedic infections.

Kaplan HB, Miranda JA, Gogola GR, Gomez K, Ambrose CG.

Diagn Microbiol Infect Dis. 2018 Jun;91(2):136-140. doi: 10.1016/j.diagmicrobio.2018.01.009. Epub 2018 Feb 2.


Somatic evolutionary timings of driver mutations.

Gomez K, Miura S, Huuki LA, Spell BS, Townsend JP, Kumar S.

BMC Cancer. 2018 Jan 18;18(1):85. doi: 10.1186/s12885-017-3977-y.


Opioid treatment for mixed pain in pediatric patients assisted by the Palliative Care team. Five years of experience.

Yazde Puleio ML, Gómez KV, Majdalani A, Pigliapoco V, Santos Chocler G.

Arch Argent Pediatr. 2018 Feb 1;116(1):62-64. doi: 10.5546/aap.2018.eng.62. English, Spanish.


Plasticity in the Interoceptive System.

Torrealba F, Madrid C, Contreras M, Gómez K.

Adv Exp Med Biol. 2017;1015:59-74. doi: 10.1007/978-3-319-62817-2_4. Review.


Correction: Methodological approach to the ex vivo expansion and detection of T. cruzi-specific T cells from chronic Chagas disease patients.

Acevedo GR, Longhi SA, Bunying A, Sabri N, Atienza A, Zago MP, Santos R, Judkowski VA, Pinilla C, Gómez KA.

PLoS One. 2017 Aug 31;12(8):e0184467. doi: 10.1371/journal.pone.0184467. eCollection 2017.


Use of a patient empowerment tool for hand hygiene.

Lastinger A, Gomez K, Manegold E, Khakoo R.

Am J Infect Control. 2017 Aug 1;45(8):824-829. doi: 10.1016/j.ajic.2017.02.010.


High levels of adherence to a rectal microbicide gel and to oral Pre-Exposure Prophylaxis (PrEP) achieved in MTN-017 among men who have sex with men (MSM) and transgender women.

Carballo-Diéguez A, Balán IC, Brown W 3rd, Giguere R, Dolezal C, Leu CS, Marzinke MA, Hendrix CW, Piper JM, Richardson BA, Grossman C, Johnson S, Gomez K, Horn S, Kunjara Na Ayudhya RP, Patterson K, Jacobson C, Bekker LG, Chariyalertsak S, Chitwarakorn A, Gonzales P, Holtz TH, Liu A, Mayer KH, Zorrilla C, Lama J, McGowan I, Cranston RD.

PLoS One. 2017 Jul 27;12(7):e0181607. doi: 10.1371/journal.pone.0181607. eCollection 2017.


Quality assurance and tests of platelet function.

Jennings I, Perry D, Watson H, Alikhan R, Laffan M, Gomez K, Kitchen S, Walker I; Haemostasis and Thrombosis Task Force of the British Society for Haematology & UK NEQAS for Blood Coagulation.

Br J Haematol. 2018 May;181(4):560-561. doi: 10.1111/bjh.14668. Epub 2017 Jun 27. No abstract available.


Bimagrumab improves body composition and insulin sensitivity in insulin-resistant individuals.

Garito T, Roubenoff R, Hompesch M, Morrow L, Gomez K, Rooks D, Meyers C, Buchsbaum MS, Neelakantham S, Swan T, Filosa LA, Laurent D, Petricoul O, Zakaria M.

Diabetes Obes Metab. 2018 Jan;20(1):94-102. doi: 10.1111/dom.13042. Epub 2017 Aug 2.


Diagnosis of inherited bleeding disorders in the genomic era.

Sivapalaratnam S, Collins J, Gomez K.

Br J Haematol. 2017 Nov;179(3):363-376. doi: 10.1111/bjh.14796. Epub 2017 Jun 14. Review.


Methodological approach to the ex vivo expansion and detection of T. cruzi-specific T cells from chronic Chagas disease patients.

Acevedo GR, Longhi SA, Bunying A, Sabri N, Atienza A, Zago MP, Santos R, Judkowski VA, Pinilla C, Gómez KA.

PLoS One. 2017 May 26;12(5):e0178380. doi: 10.1371/journal.pone.0178380. eCollection 2017. Erratum in: PLoS One. 2017 Aug 31;12 (8):e0184467.


Super-resolution microscopy in the diagnosis of platelet granule disorders.

Knight AE, Gomez K, Cutler DF.

Expert Rev Hematol. 2017 May;10(5):375-381. doi: 10.1080/17474086.2017.1315302. Epub 2017 Apr 13. Review.


Managing outpatient consultations: from referral to discharge.

Mitchell R, Jacob H, Morrissey B, Macaulay C, Gomez K, Fertleman C.

Arch Dis Child Educ Pract Ed. 2017 Aug;102(4):200-206. doi: 10.1136/archdischild-2016-311414. Epub 2017 Mar 9.


Dawning of the age of genomics for platelet granule disorders: improving insight, diagnosis and management.

Bariana TK, Ouwehand WH, Guerrero JA, Gomez K; BRIDGE Bleeding, Thrombotic and Platelet Disorders and ThromboGenomics Consortia.

Br J Haematol. 2017 Mar;176(5):705-720. doi: 10.1111/bjh.14471. Epub 2016 Dec 16. Review.


Predicting patterns of long-term adaptation and extinction with population genetics.

Bertram J, Gomez K, Masel J.

Evolution. 2017 Feb;71(2):204-214. doi: 10.1111/evo.13116. Epub 2016 Dec 9.


[Evaluation of an intervention for the use of thromboprophylaxis based on electronic alert transmission to first-year medical residents from two hospitals of Lima, Peru].

Delgado-Zapata R, Ticse R, Gamarra ML, Gómez K, Mormontoy W.

Rev Peru Med Exp Salud Publica. 2016 Jul-Sep;33(3):498-506. doi: 10.17843/rpmesp.2016.333.2372. Spanish.

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