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Items: 34


The route of infection with Leptospira interrogans serovar Copenhageni affects the kinetics of bacterial dissemination and kidney colonization.

Nair N, Guedes MS, Werts C, Gomes-Solecki M.

PLoS Negl Trop Dis. 2020 Jan 6;14(1):e0007950. doi: 10.1371/journal.pntd.0007950. eCollection 2020 Jan.


Protective Immunity and New Vaccines for Lyme Disease.

Gomes-Solecki M, Arnaboldi PM, Backenson PB, Benach JL, Cooper CL, Dattwyler RJ, Diuk-Wasser M, Fikrig E, Hovius JW, Laegreid W, Lundberg U, Marconi RT, Marques AR, Molloy P, Narasimhan S, Pal U, Pedra JHF, Plotkin S, Rock DL, Rosa P, Telford SR, Tsao J, Yang XF, Schutzer SE.

Clin Infect Dis. 2019 Oct 17. pii: ciz872. doi: 10.1093/cid/ciz872. [Epub ahead of print]


A Multiplexed Serologic Test for Diagnosis of Lyme Disease for Point-of-Care Use.

Arumugam S, Nayak S, Williams T, di Santa Maria FS, Guedes MS, Chaves RC, Linder V, Marques AR, Horn EJ, Wong SJ, Sia SK, Gomes-Solecki M.

J Clin Microbiol. 2019 Nov 22;57(12). pii: e01142-19. doi: 10.1128/JCM.01142-19. Print 2019 Dec.


Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection.

Santecchia I, Vernel-Pauillac F, Rasid O, Quintin J, Gomes-Solecki M, Boneca IG, Werts C.

PLoS Pathog. 2019 May 20;15(5):e1007811. doi: 10.1371/journal.ppat.1007811. eCollection 2019 May.


Direct Diagnostic Tests for Lyme Disease.

Schutzer SE, Body BA, Boyle J, Branson BM, Dattwyler RJ, Fikrig E, Gerald NJ, Gomes-Solecki M, Kintrup M, Ledizet M, Levin AE, Lewinski M, Liotta LA, Marques A, Mead PS, Mongodin EF, Pillai S, Rao P, Robinson WH, Roth KM, Schriefer ME, Slezak T, Snyder JL, Steere AC, Witkowski J, Wong SJ, Branda JA.

Clin Infect Dis. 2019 Mar 5;68(6):1052-1057. doi: 10.1093/cid/ciy614.


Sex Matters: Male Hamsters Are More Susceptible to Lethal Infection with Lower Doses of Pathogenic Leptospira than Female Hamsters.

Gomes CK, Guedes M, Potula HH, Dellagostin OA, Gomes-Solecki M.

Infect Immun. 2018 Sep 21;86(10). pii: e00369-18. doi: 10.1128/IAI.00369-18. Print 2018 Oct.


Lactobacillus plantarum prevents and mitigates alcohol-induced disruption of colonic epithelial tight junctions, endotoxemia, and liver damage by an EGF receptor-dependent mechanism.

Shukla PK, Meena AS, Manda B, Gomes-Solecki M, Dietrich P, Dragatsis I, Rao R.

FASEB J. 2018 Jun 18:fj201800351R. doi: 10.1096/fj.201800351R. [Epub ahead of print]


Diagnosis of Human Leptospirosis in a Clinical Setting: Real-Time PCR High Resolution Melting Analysis for Detection of Leptospira at the Onset of Disease.

Esteves LM, Bulhões SM, Branco CC, Carreira T, Vieira ML, Gomes-Solecki M, Mota-Vieira L.

Sci Rep. 2018 Jun 15;8(1):9213. doi: 10.1038/s41598-018-27555-2.


Advances in Serodiagnostic Testing for Lyme Disease Are at Hand.

Branda JA, Body BA, Boyle J, Branson BM, Dattwyler RJ, Fikrig E, Gerald NJ, Gomes-Solecki M, Kintrup M, Ledizet M, Levin AE, Lewinski M, Liotta LA, Marques A, Mead PS, Mongodin EF, Pillai S, Rao P, Robinson WH, Roth KM, Schriefer ME, Slezak T, Snyder J, Steere AC, Witkowski J, Wong SJ, Schutzer SE.

Clin Infect Dis. 2018 Mar 19;66(7):1133-1139. doi: 10.1093/cid/cix943.


Recombinant E. coli Dualistic Role as an Antigen-adjuvant Delivery Vehicle for Oral Immunization.

Gomes-Solecki M, Richer L.

Methods Mol Biol. 2018;1690:347-357. doi: 10.1007/978-1-4939-7383-5_27.


Pre-treatment with Lactobacillus plantarum prevents severe pathogenesis in mice infected with Leptospira interrogans and may be associated with recruitment of myeloid cells.

Potula HH, Richer L, Werts C, Gomes-Solecki M.

PLoS Negl Trop Dis. 2017 Aug 25;11(8):e0005870. doi: 10.1371/journal.pntd.0005870. eCollection 2017 Aug.


Borrelia burgdorferi BBI39 Paralogs, Targets of Protective Immunity, Reduce Pathogen Persistence Either in Hosts or in the Vector.

Singh P, Verma D, Backstedt BT, Kaur S, Kumar M, Smith AA, Sharma K, Yang X, Azevedo JF, Gomes-Solecki M, Buyuktanir O, Pal U.

J Infect Dis. 2017 Mar 15;215(6):1000-1009. doi: 10.1093/infdis/jix036.


Animal Models of Leptospirosis: Of Mice and Hamsters.

Gomes-Solecki M, Santecchia I, Werts C.

Front Immunol. 2017 Feb 21;8:58. doi: 10.3389/fimmu.2017.00058. eCollection 2017. Review.


Eyedrop Inoculation Causes Sublethal Leptospirosis in Mice.

Sullivan JP, Nair N, Potula HH, Gomes-Solecki M.

Infect Immun. 2017 Mar 23;85(4). pii: e01050-16. doi: 10.1128/IAI.01050-16. Print 2017 Apr.


Microfluidics-based point-of-care test for serodiagnosis of Lyme Disease.

Nayak S, Sridhara A, Melo R, Richer L, Chee NH, Kim J, Linder V, Steinmiller D, Sia SK, Gomes-Solecki M.

Sci Rep. 2016 Oct 11;6:35069. doi: 10.1038/srep35069.


Oral Immunization with OspC Does Not Prevent Tick-Borne Borrelia burgdorferi Infection.

Melo R, Richer L, Johnson DL, Gomes-Solecki M.

PLoS One. 2016 Mar 18;11(3):e0151850. doi: 10.1371/journal.pone.0151850. eCollection 2016.


Mouse model for sublethal Leptospira interrogans infection.

Richer L, Potula HH, Melo R, Vieira A, Gomes-Solecki M.

Infect Immun. 2015 Dec;83(12):4693-700. doi: 10.1128/IAI.01115-15. Epub 2015 Sep 28.


Blocking pathogen transmission at the source: reservoir targeted OspA-based vaccines against Borrelia burgdorferi.

Gomes-Solecki M.

Front Cell Infect Microbiol. 2014 Sep 26;4:136. doi: 10.3389/fcimb.2014.00136. eCollection 2014. Review.


Reservoir targeted vaccine against Borrelia burgdorferi: a new strategy to prevent Lyme disease transmission.

Richer LM, Brisson D, Melo R, Ostfeld RS, Zeidner N, Gomes-Solecki M.

J Infect Dis. 2014 Jun 15;209(12):1972-80. doi: 10.1093/infdis/jiu005. Epub 2014 Feb 11.


Oral immunization with Escherichia coli expressing a lipidated form of LigA protects hamsters against challenge with Leptospira interrogans serovar Copenhageni.

Lourdault K, Wang LC, Vieira A, Matsunaga J, Melo R, Lewis MS, Haake DA, Gomes-Solecki M.

Infect Immun. 2014 Feb;82(2):893-902. doi: 10.1128/IAI.01533-13. Epub 2013 Dec 9.


Reservoir targeted vaccine for lyme borreliosis induces a yearlong, neutralizing antibody response to OspA in white-footed mice.

Meirelles Richer L, Aroso M, Contente-Cuomo T, Ivanova L, Gomes-Solecki M.

Clin Vaccine Immunol. 2011 Nov;18(11):1809-16. doi: 10.1128/CVI.05226-11. Epub 2011 Sep 14.


Linking disease and community ecology through behavioural indicators: immunochallenge of white-footed mice and its ecological impacts.

Schwanz LE, Brisson D, Gomes-Solecki M, Ostfeld RS.

J Anim Ecol. 2011 Jan;80(1):204-14. doi: 10.1111/j.1365-2656.2010.01745.x. Epub 2010 Aug 26.


Platform technology to deliver prophylactic molecules orally: an example using the Class A select agent Yersinia pestis.

del Rio B, Fuente JL, Neves V, Dattwyler R, Seegers JF, Gomes-Solecki M.

Vaccine. 2010 Sep 24;28(41):6714-22. doi: 10.1016/j.vaccine.2010.07.084. Epub 2010 Aug 8.


Immune response to Lactobacillus plantarum expressing Borrelia burgdorferi OspA is modulated by the lipid modification of the antigen.

del Rio B, Seegers JF, Gomes-Solecki M.

PLoS One. 2010 Jun 18;5(6):e11199. doi: 10.1371/journal.pone.0011199.


Comprehensive seroprofiling of sixteen B. burgdorferi OspC: implications for Lyme disease diagnostics design.

Ivanova L, Christova I, Neves V, Aroso M, Meirelles L, Brisson D, Gomes-Solecki M.

Clin Immunol. 2009 Sep;132(3):393-400. doi: 10.1016/j.clim.2009.05.017. Epub 2009 Jul 2.


Oral immunization with recombinant lactobacillus plantarum induces a protective immune response in mice with Lyme disease.

del Rio B, Dattwyler RJ, Aroso M, Neves V, Meirelles L, Seegers JF, Gomes-Solecki M.

Clin Vaccine Immunol. 2008 Sep;15(9):1429-35. doi: 10.1128/CVI.00169-08. Epub 2008 Jul 16.


Epitope length, genospecies dependency, and serum panel effect in the IR6 enzyme-linked immunosorbent assay for detection of antibodies to Borrelia burgdorferi.

Gomes-Solecki MJ, Meirelles L, Glass J, Dattwyler RJ.

Clin Vaccine Immunol. 2007 Jul;14(7):875-9. Epub 2007 May 30.


Oral vaccine that breaks the transmission cycle of the Lyme disease spirochete can be delivered via bait.

Gomes-Solecki MJ, Brisson DR, Dattwyler RJ.

Vaccine. 2006 May 15;24(20):4440-9. Epub 2005 Sep 12.


LcrV capture enzyme-linked immunosorbent assay for detection of Yersinia pestis from human samples.

Gomes-Solecki MJ, Savitt AG, Rowehl R, Glass JD, Bliska JB, Dattwyler RJ.

Clin Diagn Lab Immunol. 2005 Feb;12(2):339-46.


IFNgamma production in peripheral blood of early Lyme disease patients to hLFAalphaL (aa326-345).

Gomes-Solecki MJ, Wormser GP, Dattwyler RJ.

BMC Musculoskelet Disord. 2002 Oct 17;3:25.


Recombinant assay for serodiagnosis of Lyme disease regardless of OspA vaccination status.

Gomes-Solecki MJ, Wormser GP, Schriefer M, Neuman G, Hannafey L, Glass JD, Dattwyler RJ.

J Clin Microbiol. 2002 Jan;40(1):193-7.


A first-tier rapid assay for the serodiagnosis of Borrelia burgdorferi infection.

Gomes-Solecki MJ, Wormser GP, Persing DH, Berger BW, Glass JD, Yang X, Dattwyler RJ.

Arch Intern Med. 2001 Sep 10;161(16):2015-20.


Recombinant chimeric Borrelia proteins for diagnosis of Lyme disease.

Gomes-Solecki MJ, Dunn JJ, Luft BJ, Castillo J, Dykhuizen DE, Yang X, Glass JD, Dattwyler RJ.

J Clin Microbiol. 2000 Jul;38(7):2530-5.


A rapid test for detection of Lyme disease antibodies.

Dattwyler RJ, Gomes-Solecki M.

Am Clin Lab. 1999 Jul;18(6):6. No abstract available.


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