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Items: 1 to 50 of 156

1.

Fibrocytes in the Tumor Microenvironment.

Roife D, Fleming JB, Gomer RH.

Adv Exp Med Biol. 2020;1224:79-85. doi: 10.1007/978-3-030-35723-8_6. Review.

PMID:
32036606
2.

An improved shotgun antisense method for mutagenesis and gene identification.

Tang Y, Gomer RH.

Biotechniques. 2020 Jan 24. doi: 10.2144/btn-2019-0123. [Epub ahead of print]

3.

Extracellular signaling in Dictyostelium.

Consalvo KM, Rijal R, Tang Y, Kirolos SA, Smith MR, Gomer RH.

Int J Dev Biol. 2019;63(8-9-10):395-405. doi: 10.1387/ijdb.190259rg.

4.

Attenuated pulmonary fibrosis in sialidase-3 knockout (Neu3-/-) mice.

Karhadkar TR, Chen W, Gomer RH.

Am J Physiol Lung Cell Mol Physiol. 2020 Jan 1;318(1):L165-L179. doi: 10.1152/ajplung.00275.2019. Epub 2019 Oct 16.

PMID:
31617733
5.

Serum Amyloid P and a Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Nonintegrin Ligand Inhibit High-Fat Diet-Induced Adipose Tissue and Liver Inflammation and Steatosis in Mice.

Pilling D, Cox N, Thomson MA, Karhadkar TR, Gomer RH.

Am J Pathol. 2019 Dec;189(12):2400-2413. doi: 10.1016/j.ajpath.2019.08.005. Epub 2019 Sep 18.

PMID:
31539521
6.

The Use of Diffusion Calculations and Monte Carlo Simulations to Understand the Behavior of Cells in Dictyostelium Communities.

Gomer RH.

Comput Struct Biotechnol J. 2019 Jun 8;17:684-688. doi: 10.1016/j.csbj.2019.06.002. eCollection 2019. Review.

7.

Extracellular Polyphosphate Promotes Macrophage and Fibrocyte Differentiation, Inhibits Leukocyte Proliferation, and Acts as a Chemotactic Agent for Neutrophils.

Suess PM, Chinea LE, Pilling D, Gomer RH.

J Immunol. 2019 Jul 15;203(2):493-499. doi: 10.4049/jimmunol.1801559. Epub 2019 Jun 3.

PMID:
31160533
8.

Serum Amyloid P Component Binds Fungal Surface Amyloid and Decreases Human Macrophage Phagocytosis and Secretion of Inflammatory Cytokines.

Behrens NE, Lipke PN, Pilling D, Gomer RH, Klotz SA.

mBio. 2019 Mar 12;10(2). pii: e00218-19. doi: 10.1128/mBio.00218-19.

9.

The putative G protein-coupled receptor GrlD mediates extracellular polyphosphate sensing in Dictyostelium discoideum.

Suess PM, Tang Y, Gomer RH.

Mol Biol Cell. 2019 Apr 15;30(9):1118-1128. doi: 10.1091/mbc.E18-10-0686. Epub 2019 Feb 20.

10.

Different Isoforms of the Neuronal Guidance Molecule Slit2 Directly Cause Chemoattraction or Chemorepulsion of Human Neutrophils.

Pilling D, Chinea LE, Consalvo KM, Gomer RH.

J Immunol. 2019 Jan 1;202(1):239-248. doi: 10.4049/jimmunol.1800681. Epub 2018 Dec 3.

11.

An endogenous chemorepellent directs cell movement by inhibiting pseudopods at one side of cells.

Rijal R, Consalvo KM, Lindsey CK, Gomer RH.

Mol Biol Cell. 2019 Jan 15;30(2):242-255. doi: 10.1091/mbc.E18-09-0562. Epub 2018 Nov 21.

12.

The Development of Serum Amyloid P as a Possible Therapeutic.

Pilling D, Gomer RH.

Front Immunol. 2018 Oct 16;9:2328. doi: 10.3389/fimmu.2018.02328. eCollection 2018. Review.

13.

An Autocrine Proliferation Repressor Regulates Dictyostelium discoideum Proliferation and Chemorepulsion Using the G Protein-Coupled Receptor GrlH.

Tang Y, Wu Y, Herlihy SE, Brito-Aleman FJ, Ting JH, Janetopoulos C, Gomer RH.

mBio. 2018 Feb 13;9(1). pii: e02443-17. doi: 10.1128/mBio.02443-17.

14.

Protease activated-receptor 2 is necessary for neutrophil chemorepulsion induced by trypsin, tryptase, or dipeptidyl peptidase IV.

White MJV, Chinea LE, Pilling D, Gomer RH.

J Leukoc Biol. 2018 Jan;103(1):119-128. doi: 10.1002/JLB.3A0717-308R. Epub 2017 Dec 11.

15.

Dietary NaCl affects bleomycin-induced lung fibrosis in mice.

Chen W, Pilling D, Gomer RH.

Exp Lung Res. 2017 Nov - Dec;43(9-10):395-406. doi: 10.1080/01902148.2017.1385110. Epub 2017 Dec 8.

17.

Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model.

Karhadkar TR, Pilling D, Cox N, Gomer RH.

Sci Rep. 2017 Nov 8;7(1):15069. doi: 10.1038/s41598-017-15198-8.

18.

Identification of compounds that decrease numbers of Mycobacteria in human macrophages in the presence of serum amyloid P.

Xiang W, Cox N, Gomer RH.

J Leukoc Biol. 2017 Sep;102(3):857-869. doi: 10.1189/jlb.1A0317-118RR. Epub 2017 Aug 2.

19.

Monocyte differentiation and macrophage priming are regulated differentially by pentraxins and their ligands.

Pilling D, Galvis-Carvajal E, Karhadkar TR, Cox N, Gomer RH.

BMC Immunol. 2017 Jun 15;18(1):30. doi: 10.1186/s12865-017-0214-z.

20.

Extracellular polyphosphate signals through Ras and Akt to prime Dictyostelium discoideum cells for development.

Suess PM, Watson J, Chen W, Gomer RH.

J Cell Sci. 2017 Jul 15;130(14):2394-2404. doi: 10.1242/jcs.203372. Epub 2017 Jun 5.

21.

Functional similarities between the dictyostelium protein AprA and the human protein dipeptidyl-peptidase IV.

Herlihy SE, Tang Y, Phillips JE, Gomer RH.

Protein Sci. 2017 Mar;26(3):578-585. doi: 10.1002/pro.3107. Epub 2017 Feb 15.

22.

A canine model for neuronal ceroid lipofuscinosis highlights the promise of gene therapy for lysosomal storage diseases.

Phillips JE, Gomer RH.

Ann Transl Med. 2016 Oct;4(Suppl 1):S20. No abstract available.

23.

Evoking picomolar binding in RNA by a single phosphorodithioate linkage.

Abeydeera ND, Egli M, Cox N, Mercier K, Conde JN, Pallan PS, Mizurini DM, Sierant M, Hibti FE, Hassell T, Wang T, Liu FW, Liu HM, Martinez C, Sood AK, Lybrand TP, Frydman C, Monteiro RQ, Gomer RH, Nawrot B, Yang X.

Nucleic Acids Res. 2016 Sep 30;44(17):8052-64. doi: 10.1093/nar/gkw725. Epub 2016 Aug 26.

24.

Extracellular Polyphosphate Inhibits Proliferation in an Autocrine Negative Feedback Loop in Dictyostelium discoideum.

Suess PM, Gomer RH.

J Biol Chem. 2016 Sep 16;291(38):20260-9. doi: 10.1074/jbc.M116.737825. Epub 2016 Aug 12.

25.

Peritoneal Dialysis Fluid and Some of Its Components Potentiate Fibrocyte Differentiation.

Herlihy SE, Starke HE, Lopez-Anton M, Cox N, Keyhanian K, Fraser DJ, Gomer RH.

Perit Dial Int. 2016 Jul-Aug;36(4):367-73. doi: 10.3747/pdi.2014.00284. Epub 2015 Oct 22.

26.

Trypsin, Tryptase, and Thrombin Polarize Macrophages towards a Pro-Fibrotic M2a Phenotype.

White MJ, Gomer RH.

PLoS One. 2015 Sep 25;10(9):e0138748. doi: 10.1371/journal.pone.0138748. eCollection 2015.

27.

TNF-α-stimulated fibroblasts secrete lumican to promote fibrocyte differentiation.

Pilling D, Vakil V, Cox N, Gomer RH.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11929-34. doi: 10.1073/pnas.1507387112. Epub 2015 Sep 8.

28.

Role of the neutrophil chemorepellent soluble dipeptidyl peptidase IV in decreasing inflammation in a murine model of arthritis.

Herlihy SE, Brown ML, Pilling D, Weeks BR, Myers LK, Gomer RH.

Arthritis Rheumatol. 2015 Oct;67(10):2634-8. doi: 10.1002/art.39250.

29.

Galectin-3 Binding Protein Secreted by Breast Cancer Cells Inhibits Monocyte-Derived Fibrocyte Differentiation.

White MJ, Roife D, Gomer RH.

J Immunol. 2015 Aug 15;195(4):1858-67. doi: 10.4049/jimmunol.1500365. Epub 2015 Jul 1.

30.

DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice.

Cox N, Pilling D, Gomer RH.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8385-90. doi: 10.1073/pnas.1500956112. Epub 2015 Jun 23.

31.

The long pentraxin PTX3 promotes fibrocyte differentiation.

Pilling D, Cox N, Vakil V, Verbeek JS, Gomer RH.

PLoS One. 2015 Mar 16;10(3):e0119709. doi: 10.1371/journal.pone.0119709. eCollection 2015.

32.
33.

Fibroblasts secrete Slit2 to inhibit fibrocyte differentiation and fibrosis.

Pilling D, Zheng Z, Vakil V, Gomer RH.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18291-6. doi: 10.1073/pnas.1417426112. Epub 2014 Dec 8.

34.

A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p.

White MJ, Galvis-Carvajal E, Gomer RH.

J Immunol. 2015 Jan 1;194(1):142-50. doi: 10.4049/jimmunol.1401777. Epub 2014 Nov 26.

35.

Distinct Fcγ receptors mediate the effect of serum amyloid p on neutrophil adhesion and fibrocyte differentiation.

Cox N, Pilling D, Gomer RH.

J Immunol. 2014 Aug 15;193(4):1701-8. doi: 10.4049/jimmunol.1400281. Epub 2014 Jul 14.

36.

Secondary ion mass spectrometry imaging of Dictyostelium discoideum aggregation streams.

DeBord JD, Smith DF, Anderton CR, Heeren RM, Paša-Tolić L, Gomer RH, Fernandez-Lima FA.

PLoS One. 2014 Jun 9;9(6):e99319. doi: 10.1371/journal.pone.0099319. eCollection 2014.

37.

Serum amyloid P: a systemic regulator of the innate immune response.

Cox N, Pilling D, Gomer RH.

J Leukoc Biol. 2014 Nov;96(5):739-43. doi: 10.1189/jlb.1MR0114-068R. Epub 2014 May 7. Review.

38.
39.

Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcγRI.

Pilling D, Crawford JR, Verbeek JS, Gomer RH.

J Leukoc Biol. 2014 Aug;96(2):275-82. doi: 10.1189/jlb.3AB0913-490RR. Epub 2014 Apr 21.

40.

Persistent lung inflammation and fibrosis in serum amyloid P component (APCs-/-) knockout mice.

Pilling D, Gomer RH.

PLoS One. 2014 Apr 2;9(4):e93730. doi: 10.1371/journal.pone.0093730. eCollection 2014.

41.

A retinoblastoma orthologue is required for the sensing of a chalone in Dictyostelium discoideum.

Bakthavatsalam D, White MJ, Herlihy SE, Phillips JE, Gomer RH.

Eukaryot Cell. 2014 Mar;13(3):376-82. doi: 10.1128/EC.00306-13. Epub 2014 Jan 3.

42.

New approaches to modulating idiopathic pulmonary fibrosis.

Gomer RH.

Curr Allergy Asthma Rep. 2013 Dec;13(6):607-12. Review.

43.

Trypsin potentiates human fibrocyte differentiation.

White MJ, Glenn M, Gomer RH.

PLoS One. 2013 Aug 7;8(8):e70795. doi: 10.1371/journal.pone.0070795. eCollection 2013.

44.

Dipeptidyl peptidase IV is a human and murine neutrophil chemorepellent.

Herlihy SE, Pilling D, Maharjan AS, Gomer RH.

J Immunol. 2013 Jun 15;190(12):6468-77. doi: 10.4049/jimmunol.1202583. Epub 2013 May 15.

45.

A Dictyostelium secreted factor requires a PTEN-like phosphatase to slow proliferation and induce chemorepulsion.

Herlihy SE, Tang Y, Gomer RH.

PLoS One. 2013;8(3):e59365. doi: 10.1371/journal.pone.0059365. Epub 2013 Mar 12.

46.

Serum amyloid P inhibits granulocyte adhesion.

Maharjan AS, Roife D, Brazill D, Gomer RH.

Fibrogenesis Tissue Repair. 2013 Jan 17;6(1):2. doi: 10.1186/1755-1536-6-2.

47.

NaCl potentiates human fibrocyte differentiation.

Cox N, Pilling D, Gomer RH.

PLoS One. 2012;7(9):e45674. doi: 10.1371/journal.pone.0045674. Epub 2012 Sep 18.

48.

Differentiation of circulating monocytes into fibroblast-like cells.

Pilling D, Gomer RH.

Methods Mol Biol. 2012;904:191-206. doi: 10.1007/978-1-61779-943-3_16.

49.

A secreted protein is an endogenous chemorepellant in Dictyostelium discoideum.

Phillips JE, Gomer RH.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10990-5. doi: 10.1073/pnas.1206350109. Epub 2012 Jun 18.

50.

FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation.

Crawford JR, Pilling D, Gomer RH.

J Leukoc Biol. 2012 Oct;92(4):699-711. doi: 10.1189/jlb.0112033. Epub 2012 Apr 9.

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