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Items: 1 to 50 of 399

1.

The Polycomb Protein Bmi1 Plays a Crucial Role in the Prevention of 1,25(OH)2 D Deficiency-induced Bone Loss.

Sun H, Qiao W, Cui M, Yang C, Wang R, Goltzman D, Jin J, Miao D.

J Bone Miner Res. 2019 Nov 14. doi: 10.1002/jbmr.3921. [Epub ahead of print]

PMID:
31725940
2.

Vertebral Fractures in Individuals With Type 2 Diabetes: More Than Skeletal Complications Alone.

Koromani F, Oei L, Shevroja E, Trajanoska K, Schoufour J, Muka T, Franco OH, Ikram MA, Zillikens MC, Uitterlinden AG, Krestin GP, Anastassiades T, Josse R, Kaiser SM, Goltzman D, Lentle BC, Prior JC, Leslie WD, McCloskey E, Lamy O, Hans D, Oei EH, Rivadeneira F.

Diabetes Care. 2019 Oct 28. pii: dc190925. doi: 10.2337/dc19-0925. [Epub ahead of print]

PMID:
31658976
3.

The Aging Skeleton.

Goltzman D.

Adv Exp Med Biol. 2019;1164:153-160. doi: 10.1007/978-3-030-22254-3_12. Review.

PMID:
31576547
4.

Reduced Bone Loss Is Associated With Reduced Mortality Risk in Subjects Exposed to Nitrogen Bisphosphonates: A Mediation Analysis.

Bliuc D, Tran T, van Geel T, Adachi JD, Berger C, van den Bergh J, Eisman JA, Geusens P, Goltzman D, Hanley DA, Josse R, Kaiser S, Kovacs CS, Langsetmo L, Prior JC, Nguyen TV, Center JR; CaMOS Research Group.

J Bone Miner Res. 2019 Nov;34(11):2001-2011. doi: 10.1002/jbmr.3816. Epub 2019 Aug 12.

PMID:
31402509
5.

Vitamin D-regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification.

Nguyen-Yamamoto L, Tanaka KI, St-Arnaud R, Goltzman D.

JCI Insight. 2019 Jul 11;4(13). pii: 126467. doi: 10.1172/jci.insight.126467. eCollection 2019 Jul 11.

6.

Endocrine aryl hydrocarbon receptor signaling is induced by moderate cutaneous exposure to ultraviolet light.

Memari B, Nguyen-Yamamoto L, Salehi-Tabar R, Zago M, Fritz JH, Baglole CJ, Goltzman D, White JH.

Sci Rep. 2019 Jun 11;9(1):8486. doi: 10.1038/s41598-019-44862-4.

7.

Predictors of imminent non-vertebral fracture in elderly women with osteoporosis, low bone mass, or a history of fracture, based on data from the population-based Canadian Multicentre Osteoporosis Study (CaMos).

Adachi JD, Berger C, Barron R, Weycker D, Anastassiades TP, Davison KS, Hanley DA, Ioannidis G, Jackson SA, Josse RG, Kaiser SM, Kovacs CS, Leslie WD, Morin SN, Papaioannou A, Prior JC, Shyta E, Silvia A, Towheed T, Goltzman D.

Arch Osteoporos. 2019 May 16;14(1):53. doi: 10.1007/s11657-019-0598-x.

PMID:
31098708
8.

Longitudinal assessment of health-related quality of life in osteoporosis: data from the population-based Canadian Multicentre Osteoporosis Study.

Hopman WM, Berger C, Joseph L, Morin SN, Towheed T, Anastassiades T, Adachi JD, Hanley DA, Prior JC, Goltzman D; CaMos Research Group.

Osteoporos Int. 2019 Aug;30(8):1635-1644. doi: 10.1007/s00198-019-05000-y. Epub 2019 May 8.

PMID:
31069440
9.

Parity and lactation are not associated with incident fragility fractures or radiographic vertebral fractures over 16 years of follow-up: Canadian Multicentre Osteoporosis Study (CaMos).

Cooke-Hubley S, Gao Z, Mugford G, Kaiser SM, Goltzman D, Leslie WD, Davison KS, Brown JP, Probyn L, Lentle B, Prior JC, Kovacs CS.

Arch Osteoporos. 2019 Apr 29;14(1):49. doi: 10.1007/s11657-019-0601-6.

PMID:
31037359
10.

Author Correction: An atlas of genetic influences on osteoporosis in humans and mice.

Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG; 23andMe Research Team, Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB.

Nat Genet. 2019 May;51(5):920. doi: 10.1038/s41588-019-0415-x.

PMID:
30988516
11.

1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling.

Chen L, Yang R, Qiao W, Zhang W, Chen J, Mao L, Goltzman D, Miao D.

Aging Cell. 2019 Jun;18(3):e12951. doi: 10.1111/acel.12951. Epub 2019 Mar 24.

12.

Incident Fragility Fractures Have a Long-Term Negative Impact on Health-Related Quality of Life of Older People: The Canadian Multicentre Osteoporosis Study.

Borhan S, Papaioannou A, Gajic-Veljanoski O, Kennedy C, Ioannidis G, Berger C, Goltzman D, Josse R, Kovacs CS, Hanley DA, Prior JC, Morin SN, Kaiser SM, Cheung AM, Thabane L, Adachi J; CaMos Research Group.

J Bone Miner Res. 2019 May;34(5):838-848. doi: 10.1002/jbmr.3666. Epub 2019 Feb 5.

PMID:
30723960
13.

Frailty and Risk of Fractures in Patients With Type 2 Diabetes.

Li G, Prior JC, Leslie WD, Thabane L, Papaioannou A, Josse RG, Kaiser SM, Kovacs CS, Anastassiades T, Towheed T, Davison KS, Levine M, Goltzman D, Adachi JD; CaMos Research Group.

Diabetes Care. 2019 Apr;42(4):507-513. doi: 10.2337/dc18-1965. Epub 2019 Jan 28.

PMID:
30692240
14.

The Radiology of Osteoporotic Vertebral Fractures Revisited.

Lentle B, Koromani F, Brown JP, Oei L, Ward L, Goltzman D, Rivadeneira F, Leslie WD, Probyn L, Prior J, Hammond I, Cheung AM, Oei EH; Vertebral Fracture Research Groups of the CaMos, STOPP, and Rotterdam Studies.

J Bone Miner Res. 2019 Mar;34(3):409-418. doi: 10.1002/jbmr.3669. Epub 2019 Feb 27. Review.

PMID:
30645770
15.

Nonparathyroid Hypercalcemia.

Goltzman D.

Front Horm Res. 2019;51:77-90. doi: 10.1159/000491040. Epub 2018 Nov 19. Review.

PMID:
30641526
16.

Mortality risk reduction differs according to bisphosphonate class: a 15-year observational study.

Bliuc D, Tran T, van Geel T, Adachi JD, Berger C, van den Bergh J, Eisman JA, Geusens P, Goltzman D, Hanley DA, Josse RG, Kaiser S, Kovacs CS, Langsetmo L, Prior JC, Nguyen TV, Center JR; CaMOS Research Group.

Osteoporos Int. 2019 Apr;30(4):817-828. doi: 10.1007/s00198-018-4806-0. Epub 2019 Jan 3.

PMID:
30607457
17.

An atlas of genetic influences on osteoporosis in humans and mice.

Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG; 23andMe Research Team, Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB.

Nat Genet. 2019 Feb;51(2):258-266. doi: 10.1038/s41588-018-0302-x. Epub 2018 Dec 31. Erratum in: Nat Genet. 2019 May;51(5):920.

18.

Evolution of Our Understanding of the Hyperparathyroid Syndromes: A Historical Perspective.

Marx SJ, Goltzman D.

J Bone Miner Res. 2019 Jan;34(1):22-37. doi: 10.1002/jbmr.3650. Epub 2018 Dec 10. Review.

19.

Endogenous Parathyroid Hormone-Related Protein Compensates for the Absence of Parathyroid Hormone in Promoting Bone Accrual In Vivo in a Model of Bone Marrow Ablation.

Zhu Q, Zhou X, Zhu M, Wang Q, Goltzman D, Karaplis A, Miao D.

J Bone Miner Res. 2018 Dec;33(12):2239-2241. doi: 10.1002/jbmr.3582. Epub 2018 Nov 12. No abstract available.

20.

Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study.

Samelson EJ, Broe KE, Xu H, Yang L, Boyd S, Biver E, Szulc P, Adachi J, Amin S, Atkinson E, Berger C, Burt L, Chapurlat R, Chevalley T, Ferrari S, Goltzman D, Hanley DA, Hannan MT, Khosla S, Liu CT, Lorentzon M, Mellstrom D, Merle B, Nethander M, Rizzoli R, Sornay-Rendu E, Van Rietbergen B, Sundh D, Wong AKO, Ohlsson C, Demissie S, Kiel DP, Bouxsein ML.

Lancet Diabetes Endocrinol. 2019 Jan;7(1):34-43. doi: 10.1016/S2213-8587(18)30308-5. Epub 2018 Nov 28. Erratum in: Lancet Diabetes Endocrinol. 2019 Jan;7(1):e1. Lancet Diabetes Endocrinol. 2019 Jun;7(6):e18.

PMID:
30503163
21.

The Calcium-Sensing Receptor and 25-Hydroxyvitamin D-1α-Hydroxylase Interact to Modulate Skeletal Growth and Bone Turnover.

Richard C, Huo R, Samadfam R, Bolivar I, Miao D, Brown EM, Hendy GN, Goltzman D.

J Bone Miner Res. 2018 Nov;33(11):2082-2083. doi: 10.1002/jbmr.3535. Epub 2018 Aug 13. No abstract available.

22.

Physiology of Parathyroid Hormone.

Goltzman D.

Endocrinol Metab Clin North Am. 2018 Dec;47(4):743-758. doi: 10.1016/j.ecl.2018.07.003. Epub 2018 Oct 11. Review.

PMID:
30390810
23.

Osteoporotic Vertebral Fracture Prevalence Varies Widely: Reply Letter to the Editor.

Goltzman D, Lentle BC.

J Bone Miner Res. 2018 Aug;33(8):1547. doi: 10.1002/jbmr.3540. Epub 2018 Jul 16. No abstract available.

24.

Identification of an Epigenetic Signature of Osteoporosis in Blood DNA of Postmenopausal Women.

Cheishvili D, Parashar S, Mahmood N, Arakelian A, Kremer R, Goltzman D, Szyf M, Rabbani SA.

J Bone Miner Res. 2018 Nov;33(11):1980-1989. doi: 10.1002/jbmr.3527. Epub 2018 Jul 20.

25.

DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide.

Zhang Y, Chen G, Gu Z, Sun H, Karaplis A, Goltzman D, Miao D.

Int J Biol Sci. 2018 Apr 5;14(5):508-517. doi: 10.7150/ijbs.23318. eCollection 2018.

26.

Vertebral Fractures and Morphometric Deformities.

Lentle BC, Hg Oei E, Goltzman D, Rivadeneira F, Hammond I, Oei L, Kovacs CS, Hanley DA, Prior JC, Leslie WD, Kaiser SM, Adachi JD, Probyn L, Brown J, Cheung AM, Towheed T.

J Bone Miner Res. 2018 Aug;33(8):1544-1545. doi: 10.1002/jbmr.3470. Epub 2018 Jun 21. No abstract available.

27.

Benefits and safety of dietary protein for bone health-an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation.

Rizzoli R, Biver E, Bonjour JP, Coxam V, Goltzman D, Kanis JA, Lappe J, Rejnmark L, Sahni S, Weaver C, Weiler H, Reginster JY.

Osteoporos Int. 2018 Sep;29(9):1933-1948. doi: 10.1007/s00198-018-4534-5. Epub 2018 May 8. Review.

PMID:
29740667
28.

1,25-dihydroxyvitamin D deficiency accelerates alveolar bone loss independent of aging and extracellular calcium and phosphorus.

Gong A, Chen J, Wu J, Li J, Wang L, Goltzman D, Miao D.

J Periodontol. 2018 Aug;89(8):983-994. doi: 10.1002/JPER.17-0542.

PMID:
29637561
29.

FAM210A is a novel determinant of bone and muscle structure and strength.

Tanaka KI, Xue Y, Nguyen-Yamamoto L, Morris JA, Kanazawa I, Sugimoto T, Wing SS, Richards JB, Goltzman D.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3759-E3768. doi: 10.1073/pnas.1719089115. Epub 2018 Apr 4.

30.

Physiology of the Calcium-Parathyroid Hormone-Vitamin D Axis.

Goltzman D, Mannstadt M, Marcocci C.

Front Horm Res. 2018;50:1-13. doi: 10.1159/000486060. Epub 2018 Mar 29. Review.

PMID:
29597231
31.

1,25-Dihydroxy vitamin D prevents tumorigenesis by inhibiting oxidative stress and inducing tumor cellular senescence in mice.

Chen L, Yang R, Qiao W, Yuan X, Wang S, Goltzman D, Miao D.

Int J Cancer. 2018 Jul 15;143(2):368-382. doi: 10.1002/ijc.31317. Epub 2018 Mar 1.

32.

Functions of vitamin D in bone.

Goltzman D.

Histochem Cell Biol. 2018 Apr;149(4):305-312. doi: 10.1007/s00418-018-1648-y. Epub 2018 Feb 12. Review.

PMID:
29435763
33.

Tumor-associated macrophages induce the expression of FOXQ1 to promote epithelial-mesenchymal transition and metastasis in gastric cancer cells.

Guo J, Yan Y, Yan Y, Guo Q, Zhang M, Zhang J, Goltzman D.

Oncol Rep. 2017 Oct;38(4):2003-2010. doi: 10.3892/or.2017.5877. Epub 2017 Aug 3.

34.

A 51-item calcium-focused food frequency questionnaire is a reliable tool to assess dietary calcium intake in postmenopausal women.

Ong AM, Weiler HA, Wall M, Goltzman D, Whiting SJ, Daskalopoulou SS, Morin SN.

Nutr Res. 2017 Jul;43:33-42. doi: 10.1016/j.nutres.2017.05.006. Epub 2017 May 18.

PMID:
28739052
35.

Comparative Analysis of the Radiology of Osteoporotic Vertebral Fractures in Women and Men: Cross-Sectional and Longitudinal Observations from the Canadian Multicentre Osteoporosis Study (CaMos).

Lentle BC, Berger C, Probyn L, Brown JP, Langsetmo L, Fine B, Lian K, Shergill AK, Trollip J, Jackson S, Leslie WD, Prior JC, Kaiser SM, Hanley DA, Adachi JD, Towheed T, Davison KS, Cheung AM, Goltzman D; CaMos Research Group.

J Bone Miner Res. 2018 Apr;33(4):569-579. doi: 10.1002/jbmr.3222. Epub 2017 Aug 7.

36.

Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism.

Matsumoto Y, La Rose J, Lim M, Adissu HA, Law N, Mao X, Cong F, Mera P, Karsenty G, Goltzman D, Changoor A, Zhang L, Stajkowski M, Grynpas MD, Bergmann C, Rottapel R.

J Clin Invest. 2017 Jun 30;127(7):2612-2625. doi: 10.1172/JCI92233. Epub 2017 Jun 5.

37.

Population-Wide Impact of Non-Hip Non-Vertebral Fractures on Mortality.

Tran T, Bliuc D, van Geel T, Adachi JD, Berger C, van den Bergh J, Eisman JA, Geusens P, Goltzman D, Hanley DA, Josse RG, Kaiser SM, Kovacs CS, Langsetmo L, Prior JC, Nguyen TV, Center JR.

J Bone Miner Res. 2017 Sep;32(9):1802-1810. doi: 10.1002/jbmr.3118. Epub 2017 May 15.

38.

Effects of the Administration of 25(OH) Vitamin D3 in an Experimental Model of Chronic Kidney Disease in Animals Null for 1-Alpha-Hydroxylase.

Torremadé N, Bozic M, Goltzman D, Fernandez E, Valdivielso JM.

PLoS One. 2017 Jan 20;12(1):e0170654. doi: 10.1371/journal.pone.0170654. eCollection 2017.

39.

The association between sclerostin and incident type 2 diabetes risk: a cohort study.

Yu OH, Richards B, Berger C, Josse RG, Leslie WD, Goltzman D, Kaiser SM, Kovacs CS, Davison KS.

Clin Endocrinol (Oxf). 2017 Apr;86(4):520-525. doi: 10.1111/cen.13300. Epub 2017 Jan 26.

PMID:
28090669
40.

Densitometer-Specific Differences in the Correlation Between Body Mass Index and Lumbar Spine Trabecular Bone Score.

Mazzetti G, Berger C, Leslie WD, Hans D, Langsetmo L, Hanley DA, Kovacs CS, Prior JC, Kaiser SM, Davison KS, Josse R, Papaioannou A, Adachi JR, Goltzman D, Morin SN; CaMos Research Group.

J Clin Densitom. 2017 Apr - Jun;20(2):233-238. doi: 10.1016/j.jocd.2016.11.003. Epub 2016 Dec 26.

PMID:
28034592
41.

Retraction to: Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study.

Jamal SA, Goltzman D, Hanley DA, Papaioannou A, Prior JC, Josse RG.

Osteoporos Int. 2017 Jan;28(1):421. doi: 10.1007/s00198-016-3843-9. No abstract available.

PMID:
27909783
42.

Transplantation of bone marrow-derived mesenchymal stem cells rescues partially rachitic phenotypes induced by 1,25-Dihydroxyvitamin D deficiency in mice.

Zhang Z, Yin S, Xue X, Ji J, Tong J, Goltzman D, Miao D.

Am J Transl Res. 2016 Oct 15;8(10):4382-4393. eCollection 2016.

43.

Trabecular Bone Score and Incident Fragility Fracture Risk in Adults with Reduced Kidney Function.

Naylor KL, Prior J, Garg AX, Berger C, Langsetmo L, Adachi JD, Goltzman D, Kovacs CS, Josse RG, Leslie WD.

Clin J Am Soc Nephrol. 2016 Nov 7;11(11):2032-2040. Epub 2016 Oct 24.

44.

Vascular Calcification Induced by Chronic Kidney Disease Is Mediated by an Increase of 1α-Hydroxylase Expression in Vascular Smooth Muscle Cells.

Torremadé N, Bozic M, Panizo S, Barrio-Vazquez S, Fernandez-Martín JL, Encinas M, Goltzman D, Arcidiacono MV, Fernandez E, Valdivielso JM.

J Bone Miner Res. 2016 Oct;31(10):1865-1876. doi: 10.1002/jbmr.2852. Epub 2016 May 4.

45.

Effects of dietary iron intake and chronic kidney disease on fibroblast growth factor 23 metabolism in wild-type and hepcidin knockout mice.

Hanudel MR, Chua K, Rappaport M, Gabayan V, Valore E, Goltzman D, Ganz T, Nemeth E, Salusky IB.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1369-F1377. doi: 10.1152/ajprenal.00281.2016. Epub 2016 Oct 12.

46.

Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus.

Khan AA, Hanley DA, Rizzoli R, Bollerslev J, Young JE, Rejnmark L, Thakker R, D'Amour P, Paul T, Van Uum S, Shrayyef MZ, Goltzman D, Kaiser S, Cusano NE, Bouillon R, Mosekilde L, Kung AW, Rao SD, Bhadada SK, Clarke BL, Liu J, Duh Q, Lewiecki EM, Bandeira F, Eastell R, Marcocci C, Silverberg SJ, Udelsman R, Davison KS, Potts JT Jr, Brandi ML, Bilezikian JP.

Osteoporos Int. 2017 Jan;28(1):1-19. doi: 10.1007/s00198-016-3716-2. Epub 2016 Sep 9. Review.

47.

Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D.

Nguyen-Yamamoto L, Karaplis AC, St-Arnaud R, Goltzman D.

J Am Soc Nephrol. 2017 Feb;28(2):586-597. doi: 10.1681/ASN.2016010066. Epub 2016 Aug 17.

48.

The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development.

Camirand A, Goltzman D, Gupta A, Kaouass M, Panda D, Karaplis A.

PLoS One. 2016 Jul 27;11(7):e0160034. doi: 10.1371/journal.pone.0160034. eCollection 2016.

49.

Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease.

Manousaki D, Mokry LE, Ross S, Goltzman D, Richards JB.

Circ Cardiovasc Genet. 2016 Aug;9(4):349-56. doi: 10.1161/CIRCGENETICS.116.001396. Epub 2016 Jul 14.

PMID:
27418593
50.

Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment.

Zhou X, Dai X, Wu X, Ji J, Karaplis A, Goltzman D, Yang X, Miao D.

Sci Rep. 2016 Jul 4;6:29171. doi: 10.1038/srep29171.

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