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Items: 1 to 50 of 52

1.

Staphylococcus aureus Lipoteichoic Acid Initiates a TSLP-Basophil-IL4 Axis in the Skin.

Brauweiler AM, Goleva E, Leung DYM.

J Invest Dermatol. 2019 Sep 17. pii: S0022-202X(19)33230-0. doi: 10.1016/j.jid.2019.09.004. [Epub ahead of print] No abstract available.

PMID:
31539531
2.

Side-by-Side Comparison of Skin Biopsies and Skin Tape Stripping Highlights Abnormal Stratum Corneum in Atopic Dermatitis.

Kim BE, Goleva E, Kim PS, Norquest K, Bronchick C, Taylor P, Leung DYM.

J Invest Dermatol. 2019 Jun 6. pii: S0022-202X(19)31632-X. doi: 10.1016/j.jid.2019.03.1160. [Epub ahead of print]

PMID:
31176708
3.

The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype.

Leung DYM, Calatroni A, Zaramela LS, LeBeau PK, Dyjack N, Brar K, David G, Johnson K, Leung S, Ramirez-Gama M, Liang B, Rios C, Montgomery MT, Richers BN, Hall CF, Norquest KA, Jung J, Bronova I, Kreimer S, Talbot CC Jr, Crumrine D, Cole RN, Elias P, Zengler K, Seibold MA, Berdyshev E, Goleva E.

Sci Transl Med. 2019 Feb 20;11(480). pii: eaav2685. doi: 10.1126/scitranslmed.aav2685.

PMID:
30787169
4.

Staphylococcus aureus Lipoteichoic Acid Damages the Skin Barrier through an IL-1-Mediated Pathway.

Brauweiler AM, Goleva E, Leung DYM.

J Invest Dermatol. 2019 Aug;139(8):1753-1761.e4. doi: 10.1016/j.jid.2019.02.006. Epub 2019 Feb 16.

PMID:
30779913
5.

Epithelial barrier repair and prevention of allergy.

Goleva E, Berdyshev E, Leung DY.

J Clin Invest. 2019 Apr 1;129(4):1463-1474. doi: 10.1172/JCI124608. Epub 2019 Feb 18. Review.

6.

Expression and function of the ectopic olfactory receptor OR10G7 in patients with atopic dermatitis.

Tham EH, Dyjack N, Kim BE, Rios C, Seibold MA, Leung DYM, Goleva E.

J Allergy Clin Immunol. 2019 May;143(5):1838-1848.e4. doi: 10.1016/j.jaci.2018.11.004. Epub 2018 Nov 14.

PMID:
30445058
7.

Expression of corticosteroid-regulated genes by PBMCs in children with asthma.

Goleva E, Babineau DC, Gill MA, Jackson LP, Shao B, Hu Z, Liu AH, Visness CM, Sorkness CA, Leung DYM, Togias A, Busse WW.

J Allergy Clin Immunol. 2019 Mar;143(3):940-947.e6. doi: 10.1016/j.jaci.2018.06.043. Epub 2018 Jul 27.

PMID:
30059697
8.

Lipid abnormalities in atopic skin are driven by type 2 cytokines.

Berdyshev E, Goleva E, Bronova I, Dyjack N, Rios C, Jung J, Taylor P, Jeong M, Hall CF, Richers BN, Norquest KA, Zheng T, Seibold MA, Leung DY.

JCI Insight. 2018 Feb 22;3(4). pii: 98006. doi: 10.1172/jci.insight.98006. eCollection 2018 Feb 22.

9.

Minimally invasive skin tape strip RNA sequencing identifies novel characteristics of the type 2-high atopic dermatitis disease endotype.

Dyjack N, Goleva E, Rios C, Kim BE, Bin L, Taylor P, Bronchick C, Hall CF, Richers BN, Seibold MA, Leung DYM.

J Allergy Clin Immunol. 2018 Apr;141(4):1298-1309. doi: 10.1016/j.jaci.2017.10.046. Epub 2018 Jan 6.

10.

Skin Wound Healing Is Accelerated by a Lipid Mixture Representing Major Lipid Components of Chamaecyparis obtusa Plant Extract.

Kim BE, Goleva E, Hall CF, Park SH, Lee UH, Brauweiler AM, Streib JE, Richers BN, Kim G, Leung DYM.

J Invest Dermatol. 2018 May;138(5):1176-1186. doi: 10.1016/j.jid.2017.11.039. Epub 2017 Dec 24.

PMID:
29277539
11.

Staphylococcus aureus Lipoteichoic Acid Inhibits Keratinocyte Differentiation through a p63-Mediated Pathway.

Brauweiler AM, Hall CF, Goleva E, Leung DYM.

J Invest Dermatol. 2017 Sep;137(9):2030-2033. doi: 10.1016/j.jid.2017.05.003. Epub 2017 May 18. No abstract available.

12.

Airway microbiome and responses to corticosteroids in corticosteroid-resistant asthma patients treated with acid suppression medications.

Goleva E, Harris JK, Robertson CE, Jackson LP, Martin RJ, Leung DYM.

J Allergy Clin Immunol. 2017 Sep;140(3):860-862.e1. doi: 10.1016/j.jaci.2017.03.011. Epub 2017 May 3. No abstract available.

PMID:
28477847
13.

Interferon-γ Protects from Staphylococcal Alpha Toxin-Induced Keratinocyte Death through Apolipoprotein L1.

Brauweiler AM, Goleva E, Leung DYM.

J Invest Dermatol. 2016 Mar;136(3):658-664. doi: 10.1016/j.jid.2015.12.006. Epub 2015 Dec 14.

14.

Corticosteroid pharmacokinetic abnormalities in overweight and obese corticosteroid resistant asthmatics.

Goleva E, Covar R, Martin RJ, Leung DY.

J Allergy Clin Immunol Pract. 2016 Mar-Apr;4(2):357-60.e2. doi: 10.1016/j.jaip.2015.11.013. Epub 2016 Jan 18. No abstract available.

15.

Activated p38 MAPK in Peripheral Blood Monocytes of Steroid Resistant Asthmatics.

Li LB, Leung DY, Goleva E.

PLoS One. 2015 Oct 30;10(10):e0141909. doi: 10.1371/journal.pone.0141909. eCollection 2015.

16.

Th2 Cytokines Suppress Lipoteichoic Acid-Induced Matrix Metalloproteinase Expression and Keratinocyte Migration in Response to Wounding.

Brauweiler AM, Goleva E, Hall CF, Leung DYM.

J Invest Dermatol. 2015 Oct;135(10):2550-2553. doi: 10.1038/jid.2015.181. Epub 2015 May 7. No abstract available.

17.

Th2 cytokines increase Staphylococcus aureus alpha toxin-induced keratinocyte death through the signal transducer and activator of transcription 6 (STAT6).

Brauweiler AM, Goleva E, Leung DYM.

J Invest Dermatol. 2014 Aug;134(8):2114-2121. doi: 10.1038/jid.2014.43. Epub 2014 Jan 27.

18.

Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma.

Zhang Y, Leung DY, Goleva E.

J Allergy Clin Immunol. 2014 Jun;133(6):1744-52.e1. doi: 10.1016/j.jaci.2013.12.004. Epub 2014 Jan 11.

19.

The effects of airway microbiome on corticosteroid responsiveness in asthma.

Goleva E, Jackson LP, Harris JK, Robertson CE, Sutherland ER, Hall CF, Good JT Jr, Gelfand EW, Martin RJ, Leung DY.

Am J Respir Crit Care Med. 2013 Nov 15;188(10):1193-201. doi: 10.1164/rccm.201304-0775OC.

20.

IL-13-producing BLT1-positive CD8 cells are increased in asthma and are associated with airway obstruction.

Dakhama A, Collins ML, Ohnishi H, Goleva E, Leung DY, Alam R, Sutherland ER, Martin RJ, Gelfand EW.

Allergy. 2013;68(5):666-73. doi: 10.1111/all.12135. Epub 2013 Apr 10.

21.

Vitamin D enhances glucocorticoid action in human monocytes: involvement of granulocyte-macrophage colony-stimulating factor and mediator complex subunit 14.

Zhang Y, Leung DY, Goleva E.

J Biol Chem. 2013 May 17;288(20):14544-53. doi: 10.1074/jbc.M112.427054. Epub 2013 Apr 9.

22.

Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin-induced keratinocyte death.

Brauweiler AM, Bin L, Kim BE, Oyoshi MK, Geha RS, Goleva E, Leung DY.

J Allergy Clin Immunol. 2013 Feb;131(2):421-7.e1-2. doi: 10.1016/j.jaci.2012.10.030. Epub 2012 Dec 11.

23.

Obesity impairs apoptotic cell clearance in asthma.

Fernandez-Boyanapalli R, Goleva E, Kolakowski C, Min E, Day B, Leung DY, Riches DW, Bratton DL, Sutherland ER.

J Allergy Clin Immunol. 2013 Apr;131(4):1041-7, 1047.e1-3. doi: 10.1016/j.jaci.2012.09.028. Epub 2012 Nov 13.

24.

Staphylococcus aureus α-toxin modulates skin host response to viral infection.

Bin L, Kim BE, Brauweiler A, Goleva E, Streib J, Ji Y, Schlievert PM, Leung DY.

J Allergy Clin Immunol. 2012 Sep;130(3):683-691.e2. doi: 10.1016/j.jaci.2012.06.019. Epub 2012 Jul 26.

25.

Cluster analysis of obesity and asthma phenotypes.

Sutherland ER, Goleva E, King TS, Lehman E, Stevens AD, Jackson LP, Stream AR, Fahy JV, Leung DY; Asthma Clinical Research Network.

PLoS One. 2012;7(5):e36631. doi: 10.1371/journal.pone.0036631. Epub 2012 May 11.

26.

Induction of GITRL expression in human keratinocytes by Th2 cytokines and TNF-α: implications for atopic dermatitis.

Byrne AM, Goleva E, Chouiali F, Kaplan MH, Hamid QA, Leung DY.

Clin Exp Allergy. 2012 Apr;42(4):550-9. doi: 10.1111/j.1365-2222.2012.03956.x.

27.

Steroid requirements and immune associations with vitamin D are stronger in children than adults with asthma.

Goleva E, Searing DA, Jackson LP, Richers BN, Leung DY.

J Allergy Clin Immunol. 2012 May;129(5):1243-51. doi: 10.1016/j.jaci.2012.01.044. Epub 2012 Feb 11.

28.

Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1.

Zhang Y, Leung DY, Richers BN, Liu Y, Remigio LK, Riches DW, Goleva E.

J Immunol. 2012 Mar 1;188(5):2127-35. doi: 10.4049/jimmunol.1102412. Epub 2012 Feb 1.

29.

Usefulness of PBMCs to predict clinical response to corticosteroids in asthmatic patients.

Goleva E, Jackson LP, Gleason M, Leung DY.

J Allergy Clin Immunol. 2012 Mar;129(3):687-693.e1. doi: 10.1016/j.jaci.2011.12.001. Epub 2012 Jan 10.

30.

Inhibition of histone deacetylase 2 expression by elevated glucocorticoid receptor beta in steroid-resistant asthma.

Li LB, Leung DY, Martin RJ, Goleva E.

Am J Respir Crit Care Med. 2010 Oct 1;182(7):877-83. doi: 10.1164/rccm.201001-0015OC. Epub 2010 Jun 10.

31.

Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use.

Searing DA, Zhang Y, Murphy JR, Hauk PJ, Goleva E, Leung DY.

J Allergy Clin Immunol. 2010 May;125(5):995-1000. doi: 10.1016/j.jaci.2010.03.008. Epub 2010 Apr 9.

32.

Vitamin D levels, lung function, and steroid response in adult asthma.

Sutherland ER, Goleva E, Jackson LP, Stevens AD, Leung DY.

Am J Respir Crit Care Med. 2010 Apr 1;181(7):699-704. doi: 10.1164/rccm.200911-1710OC. Epub 2010 Jan 14.

33.

Estrogen inhibits glucocorticoid action via protein phosphatase 5 (PP5)-mediated glucocorticoid receptor dephosphorylation.

Zhang Y, Leung DY, Nordeen SK, Goleva E.

J Biol Chem. 2009 Sep 4;284(36):24542-52. doi: 10.1074/jbc.M109.021469. Epub 2009 Jul 8.

34.
35.

IFN-gamma reverses IL-2- and IL-4-mediated T-cell steroid resistance.

Goleva E, Li LB, Leung DY.

Am J Respir Cell Mol Biol. 2009 Feb;40(2):223-30. doi: 10.1165/rcmb.2007-0327OC. Epub 2008 Sep 5.

36.

Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages.

Goleva E, Hauk PJ, Hall CF, Liu AH, Riches DW, Martin RJ, Leung DY.

J Allergy Clin Immunol. 2008 Sep;122(3):550-9.e3. doi: 10.1016/j.jaci.2008.07.007.

37.

Neutrophilic airway inflammation and association with bacterial lipopolysaccharide in children with asthma and wheezing.

Hauk PJ, Krawiec M, Murphy J, Boguniewicz J, Schiltz A, Goleva E, Liu AH, Leung DY.

Pediatr Pulmonol. 2008 Sep;43(9):916-23. doi: 10.1002/ppul.20880.

PMID:
18668688
38.

Body mass and glucocorticoid response in asthma.

Sutherland ER, Goleva E, Strand M, Beuther DA, Leung DY.

Am J Respir Crit Care Med. 2008 Oct 1;178(7):682-7. doi: 10.1164/rccm.200801-076OC. Epub 2008 Jul 17.

39.

Airway remodeling and lack of bronchodilator response in steroid-resistant asthma.

Goleva E, Hauk PJ, Boguniewicz J, Martin RJ, Leung DY.

J Allergy Clin Immunol. 2007 Nov;120(5):1065-72. Epub 2007 Sep 27.

40.

ATF2 impairs glucocorticoid receptor-mediated transactivation in human CD8+ T cells.

Li LB, Leung DY, Strand MJ, Goleva E.

Blood. 2007 Sep 1;110(5):1570-7. Epub 2007 May 24.

41.

Divergent expression and function of glucocorticoid receptor β in human monocytes and T cells.

Li LB, Leung DYM, Hall CF, Goleva E.

J Leukoc Biol. 2006 Apr;79(4):818-827. doi: 10.1189/jlb.0805466.

PMID:
29350843
42.

Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes.

Cardona ID, Goleva E, Ou LS, Leung DY.

J Allergy Clin Immunol. 2006 Mar;117(3):688-95. Epub 2006 Jan 27.

PMID:
16522472
43.

Divergent expression and function of glucocorticoid receptor beta in human monocytes and T cells.

Li LB, Leung DY, Hall CF, Goleva E.

J Leukoc Biol. 2006 Apr;79(4):818-27. Epub 2006 Feb 3.

PMID:
16461744
44.

Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma.

Goleva E, Li LB, Eves PT, Strand MJ, Martin RJ, Leung DY.

Am J Respir Crit Care Med. 2006 Mar 15;173(6):607-16. Epub 2005 Dec 30.

45.

Factors that regulate naturally occurring T regulatory cell-mediated suppression.

Goleva E, Cardona ID, Ou LS, Leung DY.

J Allergy Clin Immunol. 2005 Nov;116(5):1094-100. Review.

PMID:
16275382
47.
48.

CD56+ cells induce steroid resistance in B cells exposed to IL-15.

Xu Q, Goleva E, Ou LS, Li LB, Leung DY.

J Immunol. 2004 Jun 1;172(11):7110-5.

49.

T regulatory cells in atopic dermatitis and subversion of their activity by superantigens.

Ou LS, Goleva E, Hall C, Leung DY.

J Allergy Clin Immunol. 2004 Apr;113(4):756-63.

PMID:
15100684
50.

Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes.

Nomura I, Goleva E, Howell MD, Hamid QA, Ong PY, Hall CF, Darst MA, Gao B, Boguniewicz M, Travers JB, Leung DY.

J Immunol. 2003 Sep 15;171(6):3262-9.

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