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Patient-Centered Oncology or Population-Centered Oncology-Which Do We Want, and Which Tradeoffs Are We Willing To Accept?

Goldstein DA, Den RB.

Oncologist. 2018 Dec 6. pii: theoncologist.2018-0679. doi: 10.1634/theoncologist.2018-0679. [Epub ahead of print] No abstract available.


Vertical Hyperreflective Lesions on Optical Coherence Tomography in Vitreoretinal Lymphoma.

Deák GG, Goldstein DA, Zhou M, Fawzi AA, Jampol LM.

JAMA Ophthalmol. 2018 Nov 29. doi: 10.1001/jamaophthalmol.2018.5835. [Epub ahead of print]


The Burden of Candidate Pathogenic Variants for Kidney and Genitourinary Disorders Emerging From Exome Sequencing.

Rasouly HM, Groopman EE, Heyman-Kantor R, Fasel DA, Mitrotti A, Westland R, Bier L, Weng C, Ren Z, Copeland B, Krithivasan P, Chung WK, Sanna-Cherchi S, Goldstein DB, Gharavi AG.

Ann Intern Med. 2018 Nov 27. doi: 10.7326/M18-1241. [Epub ahead of print]


Dorsal root ganglion explants derived from chemotherapy-treated mice have reduced neurite outgrowth in culture.

Livni L, Lees JG, Barkl-Luke ME, Goldstein D, Moalem-Taylor G.

Neurosci Lett. 2018 Nov 13;694:14-19. doi: 10.1016/j.neulet.2018.11.016. [Epub ahead of print]


Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration.

Shashi V, Magiera MM, Klein D, Zaki M, Schoch K, Rudnik-Schöneborn S, Norman A, Lopes Abath Neto O, Dusl M, Yuan X, Bartesaghi L, De Marco P, Alfares AA, Marom R, Arold ST, Guzmán-Vega FJ, Pena LD, Smith EC, Steinlin M, Babiker MO, Mohassel P, Foley AR, Donkervoort S, Kaur R, Ghosh PS, Stanley V, Musaev D, Nava C, Mignot C, Keren B, Scala M, Tassano E, Picco P, Doneda P, Fiorillo C, Issa MY, Alassiri A, Alahmad A, Gerard A, Liu P, Yang Y, Ertl-Wagner B, Kranz PG, Wentzensen IM, Stucka R, Stong N, Allen AS, Goldstein DB; Undiagnosed Diseases Network, Schoser B, Rösler KM, Alfadhel M, Capra V, Chrast R, Strom TM, Kamsteeg EJ, Bönnemann CG, Gleeson JG, Martini R, Janke C, Senderek J.

EMBO J. 2018 Dec 3;37(23). pii: e100540. doi: 10.15252/embj.2018100540. Epub 2018 Nov 12.


Regorafenib treatment for patients with hepatocellular carcinoma who progressed on sorafenib-A cost-effectiveness analysis.

Shlomai A, Leshno M, Goldstein DA.

PLoS One. 2018 Nov 8;13(11):e0207132. doi: 10.1371/journal.pone.0207132. eCollection 2018.


Re: Quality of life and symptom impact of thyroid cancer: A cross-sectional survey of Canadian patients.

Alhashemi A, Jones JM, Goldstein DP, Ezzat S, Sawka AM.

Surgery. 2018 Oct 29. pii: S0039-6060(18)30675-5. doi: 10.1016/j.surg.2018.09.018. [Epub ahead of print] No abstract available.


Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma.

Karamboulas C, Bruce JP, Hope AJ, Meens J, Huang SH, Erdmann N, Hyatt E, Pereira K, Goldstein DP, Weinreb I, Su J, O'Sullivan B, Tiedemann R, Liu FF, Pugh TJ, Bratman SV, Xu W, Ailles L.

Cell Rep. 2018 Oct 30;25(5):1318-1331.e4. doi: 10.1016/j.celrep.2018.10.004.


Duration of adjuvant immunotherapy-biologic, clinical and economic considerations.

Stav I, Gyawali B, Goldstein DA.

Med Oncol. 2018 Oct 29;35(12):160. doi: 10.1007/s12032-018-1218-0.


A Systematic Review and Meta-Analysis of Subsequent Malignant Neoplasm Risk After Radioactive Iodine Treatment of Thyroid Cancer.

Yu CY, Saeed O, Goldberg AS, Farooq S, Fazelzad R, Goldstein DP, Tsang RW, Brierley JD, Ezzat S, Thabane L, Goldsmith CH, Sawka AM.

Thyroid. 2018 Nov 27. doi: 10.1089/thy.2018.0244. [Epub ahead of print]


Digoxin Is Associated With a Decreased Incidence of Angiodysplasia-Related Gastrointestinal Bleeding in Patients With Continuous-Flow Left Ventricular Assist Devices.

Vukelic S, Vlismas PP, Patel SR, Xue X, Shitole SG, Saeed O, Sims DB, Chinnadurai T, Shin JJ, Forest SJ, Goldstein DJ, Jorde UP.

Circ Heart Fail. 2018 Aug;11(8):e004899. doi: 10.1161/CIRCHEARTFAILURE.118.004899.


Evaluation of an online communication skills training programme for oncology nurses working with patients from minority backgrounds.

Kaur R, Meiser B, Zilliacus E, Tim Wong WK, Woodland L, Watts K, Tomkins S, Kissane D, Girgis A, Butow P, Hale S, Perry A, Aranda SK, Shaw T, Tebble H, Norris C, Goldstein D.

Support Care Cancer. 2018 Oct 16. doi: 10.1007/s00520-018-4507-4. [Epub ahead of print]


Factors Associated with Prolonged Survival in Left Ventricular Assist Device Recipients.

Xia Y, Forest S, Friedmann P, Chou LC, Patel S, Jorde U, Goldstein D.

Ann Thorac Surg. 2018 Oct 11. pii: S0003-4975(18)31463-2. doi: 10.1016/j.athoracsur.2018.08.054. [Epub ahead of print]


Monitoring quality of care for patients with pancreatic cancer: a modified Delphi consensus.

Maharaj AD, Ioannou L, Croagh D, Zalcberg J, Neale RE, Goldstein D, Merrett N, Kench JG, White K, Pilgrim CHC, Chantrill L, Cosman P, Kneebone A, Lipton L, Nikfarjam M, Philip J, Sandroussi C, Tagkalidis P, Chye R, Haghighi KS, Samra J, Evans SM.

HPB (Oxford). 2018 Oct 10. pii: S1365-182X(18)33948-0. doi: 10.1016/j.hpb.2018.08.016. [Epub ahead of print]


A bridge from HeartMate XVE to HeartMate 3.

Loumiotis I, Patel SR, Goldstein DJ, Forest SJ.

J Card Surg. 2018 Nov;33(11):762-764. doi: 10.1111/jocs.13934. Epub 2018 Oct 10.


meaRtools: An R package for the analysis of neuronal networks recorded on microelectrode arrays.

Gelfman S, Wang Q, Lu YF, Hall D, Bostick CD, Dhindsa R, Halvorsen M, McSweeney KM, Cotterill E, Edinburgh T, Beaumont MA, Frankel WN, Petrovski S, Allen AS, Boland MJ, Goldstein DB, Eglen SJ.

PLoS Comput Biol. 2018 Oct 1;14(10):e1006506. doi: 10.1371/journal.pcbi.1006506. eCollection 2018 Oct.


NBEA: Developmental disease gene with early generalized epilepsy phenotypes.

Mulhern MS, Stumpel C, Stong N, Brunner HG, Bier L, Lippa N, Riviello J, Rouhl RPW, Kempers M, Pfundt R, Stegmann APA, Kukolich MK, Telegrafi A, Lehman A; CAUSES study, Lopez-Rangel E, Houcinat N, Barth M, den Hollander N, Hoffer MJV, Weckhuysen S; EuroEPINOMICS-RES-MAE working group, Roovers J, Djemie T, Barca D, Ceulemans B, Craiu D, Lemke JR, Korff C, Mefford HC, Meyers CT, Siegler Z, Hiatt SM, Cooper GM, Bebin EM, Snijders Blok L, Veenstra-Knol HE, Baugh EH, Brilstra EH, Volker-Touw CML, van Binsbergen E, Revah-Politi A, Pereira E, McBrian D, Pacault M, Isidor B, Le Caignec C, Gilbert-Dussardier B, Bilan F, Heinzen EL, Goldstein DB, Stevens SJC, Sands TT.

Ann Neurol. 2018 Nov;84(5):788-795. doi: 10.1002/ana.25350. Epub 2018 Oct 25.


A tale of the twist in the outflow graft: An analysis from the MOMENTUM 3 trial.

Mehra MR, Salerno C, Naka Y, Uriel N, Cleveland JC, Horstmanshof D, Goldstein DJ; MOMENTUM 3 Investigators.

J Heart Lung Transplant. 2018 Nov;37(11):1281-1284. doi: 10.1016/j.healun.2018.08.011. Epub 2018 Aug 24. No abstract available.


Predictors of early recurrence prior to planned post-operative radiation therapy for oral cavity squamous cell carcinoma and outcomes following salvage intensified radiation therapy.

Hosni A, Huang SH, Chiu K, Xu W, Su J, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, O'Sullivan B, Ringash J, Waldron J, Spreafico A, Yu E, de Almeida JR, Monteiro E, Chepeha DB, Irish JC, Goldstein DP, Hope A.

Int J Radiat Oncol Biol Phys. 2018 Sep 20. pii: S0360-3016(18)33760-X. doi: 10.1016/j.ijrobp.2018.09.013. [Epub ahead of print]


Substantial renal conversion of L-threo-3,4-dihydroxyphenylserine (droxidopa) to norepinephrine in patients with neurogenic orthostatic hypotension.

Lamotte G, Holmes C, Sullivan P, Goldstein DS.

Clin Auton Res. 2018 Sep 18. doi: 10.1007/s10286-018-0564-5. [Epub ahead of print]


C-reactive Protein in HPV-Positive and HPV-Negative Oropharyngeal Cancer.

Johnson-Obaseki S, Caulley L, Corsten M, Liu G, Dimitroulakos J, Goldstein D, Irish J, Rider J.

Otolaryngol Head Neck Surg. 2018 Sep 18:194599818800297. doi: 10.1177/0194599818800297. [Epub ahead of print]


Volumetric Analysis of Endoscopic and Maxillary Swing Surgical Approaches for Nasopharyngectomy.

Muhanna N, Chan H, Qiu J, Daly M, Khan T, Doglietto F, Kucharczyk W, Goldstein DP, Irish JC, de Almeida JR.

J Neurol Surg B Skull Base. 2018 Oct;79(5):466-474. doi: 10.1055/s-0037-1617432. Epub 2018 Jan 19.


Impact of Dural Resection on Sinonasal Malignancies with Skull Base Encroachment or Erosion.

Ziai H, Yu E, Fu T, Muhanna N, Monteiro E, Vescan A, Zadeh G, Witterick IJ, Goldstein DP, Gentili F, de Almeida JR.

J Neurol Surg B Skull Base. 2018 Oct;79(5):419-426. doi: 10.1055/s-0037-1612617. Epub 2017 Dec 29.


Whole-Exome Sequencing Study of Extreme Phenotypes of NAFLD.

Kleinstein SE, Rein M, Abdelmalek MF, Guy CD, Goldstein DB, Mae Diehl A, Moylan CA.

Hepatol Commun. 2018 Sep 5;2(9):1021-1029. doi: 10.1002/hep4.1227. eCollection 2018 Sep.


Impact of body mass index on adverse events after implantation of left ventricular assist devices: An IMACS registry analysis.

Forest SJ, Xie R, Kirklin JK, Cowger J, Xia Y, Dipchand AI, Sivathasan C, Merry C, Lund LH, Kormos R, Hannan MM, Nakatani T, Jorde U, Goldstein DJ.

J Heart Lung Transplant. 2018 Oct;37(10):1207-1217. doi: 10.1016/j.healun.2018.06.004. Epub 2018 Jun 21.


Refining the phenotype associated with GNB1 mutations: Clinical data on 18 newly identified patients and review of the literature.

Hemati P, Revah-Politi A, Bassan H, Petrovski S, Bilancia CG, Ramsey K, Griffin NG, Bier L, Cho MT, Rosello M, Lynch SA, Colombo S, Weber A, Haug M, Heinzen EL, Sands TT, Narayanan V, Primiano M, Aggarwal VS, Millan F, Sattler-Holtrop SG, Caro-Llopis A, Pillar N, Baker J, Freedman R, Kroes HY, Sacharow S, Stong N, Lapunzina P, Schneider MC, Mendelsohn NJ, Singleton A, Loik Ramey V, Wou K, Kuzminsky A, Monfort S, Weiss M, Doyle S, Iglesias A, Martinez F, Mckenzie F, Orellana C, van Gassen KLI, Palomares M, Bazak L, Lee A, Bircher A, Basel-Vanagaite L, Hafström M, Houge G; C4RCD Research Group; DDD study, Goldstein DB, Anyane-Yeboa K.

Am J Med Genet A. 2018 Nov;176(11):2259-2275. doi: 10.1002/ajmg.a.40472. Epub 2018 Sep 8.


Information Transparency in the Drug Approval Process-Reply.

Gyawali B, Goldstein DA.

JAMA Oncol. 2018 Nov 1;4(11):1622. doi: 10.1001/jamaoncol.2018.4163. No abstract available.


IRF2BPL Is Associated with Neurological Phenotypes.

Marcogliese PC, Shashi V, Spillmann RC, Stong N, Rosenfeld JA, Koenig MK, Martínez-Agosto JA, Herzog M, Chen AH, Dickson PI, Lin HJ, Vera MU, Salamon N, Graham JM Jr, Ortiz D, Infante E, Steyaert W, Dermaut B, Poppe B, Chung HL, Zuo Z, Lee PT, Kanca O, Xia F, Yang Y, Smith EC, Jasien J, Kansagra S, Spiridigliozzi G, El-Dairi M, Lark R, Riley K, Koeberl DD, Golden-Grant K; Program for Undiagnosed Diseases (UD-PrOZA); Undiagnosed Diseases Network, Yamamoto S, Wangler MF, Mirzaa G, Hemelsoet D, Lee B, Nelson SF, Goldstein DB, Bellen HJ, Pena LDM.

Am J Hum Genet. 2018 Sep 6;103(3):456. doi: 10.1016/j.ajhg.2018.08.010. No abstract available.


Specific TCR gene rearrangements in mycosis fungoides: does advanced clinical stage show a preference?

Marks E, Wang Y, Shi Y, Susa J, Jacobson M, Goldstein DY.

J Clin Pathol. 2018 Dec;71(12):1072-1077. doi: 10.1136/jclinpath-2018-205324. Epub 2018 Aug 31.


Radiologic-Pathologic Correlation of Tumor Thickness and Its Prognostic Importance in Squamous Cell Carcinoma of the Oral Cavity: Implications for the Eighth Edition Tumor, Node, Metastasis Classification.

Weimar EAM, Huang SH, Lu L, O'Sullivan B, Perez-Ordonez B, Weinreb I, Hope A, Tong L, Goldstein D, Irish J, de Almeida JR, Bratman S, Xu W, Yu E.

AJNR Am J Neuroradiol. 2018 Oct;39(10):1896-1902. doi: 10.3174/ajnr.A5782. Epub 2018 Aug 30.


Magnetically Levitated Cardiac Pump at 2 Years.

Mehra MR, Goldstein DJ.

N Engl J Med. 2018 Aug 30;379(9):897. doi: 10.1056/NEJMc1809738. No abstract available.


The Collaborative Ocular Tuberculosis Study (COTS)-1: A Multinational Description of the Spectrum of Choroidal Involvement in 245 Patients with Tubercular Uveitis.

Agrawal R, Gunasekeran DV, Agarwal A, Carreño E, Aggarwal K, Gupta B, Raje D, Murthy SI, Westcott M, Chee SP, McCluskey P, Ling HS, Teoh S, Cimino L, Biswas J, Narain S, Agarwal M, Mahendradas P, Khairallah M, Jones N, Tugal-Tutkun I, Babu K, Basu S, Lee R, Al-Dhibi H, Bodaghi B, Invernizzi A, Goldstein DA, Herbort CP, Barisani-Asenbauer T, González-López JJ, Androudi S, Bansal R, Moharana B, Mahajan S, Esposti S, Tasiopoulou A, Nadarajah S, Agarwal M, Abraham S, Vala R, Lord J, Singh R, Sharma A, Sharma K, Zierhut M, Kon OM, Kempen J, Cunningham ET, Rousselot A, Nguyen QD, Pavesio C, Gupta V.

Ocul Immunol Inflamm. 2018 Aug 29:1-11. doi: 10.1080/09273948.2018.1489061. [Epub ahead of print]


Weight-based dosing vs fixed dosing of pembrolizumab: an economic analysis.

Goldstein D.

Clin Adv Hematol Oncol. 2018 Aug;16(8):549-551. No abstract available.


Time Is Money: Optimizing the Scheduling of Nivolumab.

Ratain MJ, Goldstein DA.

J Clin Oncol. 2018 Aug 27:JCO1800045. doi: 10.1200/JCO.18.00045. [Epub ahead of print] No abstract available.


Improving on Tail-of-the-Curve Evaluation With the American Society of Clinical Oncology Value Framework-Reply.

Ben-Aharon O, Goldstein DA.

JAMA Oncol. 2018 Oct 1;4(10):1438-1439. doi: 10.1001/jamaoncol.2018.3295. No abstract available.


Cardiac transplantation from non-viremic hepatitis C donors.

Patel SR, Madan S, Saeed O, Sims DB, Shin JJ, Nucci C, Borukhov E, Goldstein DY, Jakobleff W, Forest S, Vukelic S, Murthy S, Reinus J, Puius Y, Goldstein DJ, Jorde UP.

J Heart Lung Transplant. 2018 Oct;37(10):1254-1260. doi: 10.1016/j.healun.2018.06.012. Epub 2018 Aug 17.


Symptom burden in adults with thyroid cancer.

Sawka AM, Watt S, Rodin G, Ezzat S, Howell D, Tsang RW, Brierley JD, Krzyzanowska MK, Goldstein D, Li M.

Psychooncology. 2018 Oct;27(10):2517-2519. doi: 10.1002/pon.4853. Epub 2018 Aug 31. No abstract available.


The Influence of Race and Sex on the Side Effect Profile of Methotrexate in the Treatment of Uveitis.

LaMattina KC, Escott SM, Malalis JF, Mai D, Harada Y, Goldstein DA.

Ocul Immunol Inflamm. 2018 Aug 13:1-5. doi: 10.1080/09273948.2018.1498905. [Epub ahead of print]


Cerebrospinal Fluid-Directed rAAV9-rsATP7A Plus Subcutaneous Copper Histidinate Advance Survival and Outcomes in a Menkes Disease Mouse Model.

Haddad MR, Choi EY, Zerfas PM, Yi L, Martinelli D, Sullivan P, Goldstein DS, Centeno JA, Brinster LR, Ralle M, Kaler SG.

Mol Ther Methods Clin Dev. 2018 Jul 9;10:165-178. doi: 10.1016/j.omtm.2018.07.002. eCollection 2018 Sep 21.


Roles of cardiac sympathetic neuroimaging in autonomic medicine.

Goldstein DS, Cheshire WP Jr.

Clin Auton Res. 2018 Aug;28(4):397-410. doi: 10.1007/s10286-018-0547-6. Epub 2018 Jul 30. Review.


IRF2BPL Is Associated with Neurological Phenotypes.

Marcogliese PC, Shashi V, Spillmann RC, Stong N, Rosenfeld JA, Koenig MK, Martínez-Agosto JA, Herzog M, Chen AH, Dickson PI, Lin HJ, Vera MU, Salamon N, Graham JM Jr, Ortiz D, Infante E, Steyaert W, Dermaut B, Poppe B, Chung HL, Zuo Z, Lee PT, Kanca O, Xia F, Yang Y, Smith EC, Jasien J, Kansagra S, Spiridigliozzi G, El-Dairi M, Lark R, Riley K, Koeberl DD, Golden-Grant K; Program for Undiagnosed Diseases (UD-PrOZA); Undiagnosed Diseases Network, Yamamoto S, Wangler MF, Mirzaa G, Hemelsoet D, Lee B, Nelson SF, Goldstein DB, Bellen HJ, Pena LDM.

Am J Hum Genet. 2018 Aug 2;103(2):245-260. doi: 10.1016/j.ajhg.2018.07.006. Epub 2018 Jul 26. Erratum in: Am J Hum Genet. 2018 Sep 6;103(3):456.


The HeartMate 3 pump: Overcoming the hemocompatibility gap.

Cleveland JC Jr, Goldstein DJ.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2140-2142. doi: 10.1016/j.jtcvs.2018.05.055. Epub 2018 Jun 4. No abstract available.


Exome sequencing of an adolescent with nonalcoholic fatty liver disease identifies a clinically actionable case of Wilson disease.

Wattacheril J, Shea PR, Mohammad S, Behling C, Aggarwal V, Wilson LA, Yates KP, Ito J, Fishbein M, Stong N, Lavine JE, Goldstein DB.

Cold Spring Harb Mol Case Stud. 2018 Oct 1;4(5). pii: a003087. doi: 10.1101/mcs.a003087. Print 2018 Oct.


A real-world analysis of cancer drug wastage due to oversized vials.

Liran O, Prus J, Gordon N, Almog V, Gruenewald T, Goldstein DA.

J Am Pharm Assoc (2003). 2018 Nov - Dec;58(6):643-646. doi: 10.1016/j.japh.2018.06.004. Epub 2018 Jul 13.


Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease.

Raghavan NS, Brickman AM, Andrews H, Manly JJ, Schupf N, Lantigua R, Wolock CJ, Kamalakaran S, Petrovski S, Tosto G, Vardarajan BN, Goldstein DB, Mayeux R; Alzheimer's Disease Sequencing Project.

Ann Clin Transl Neurol. 2018 May 24;5(7):832-842. doi: 10.1002/acn3.582. eCollection 2018 Jul.


[Differences in the cytocompatibility of bone-plastic materials from xenogeneic hydroxyapatite with stem cells from human exfoliated deciduous teeth and adipose tissue-derived mesenchymal stem cells].

Vasilyev AV, Zorina OA, Magomedov RN, Bukharova TB, Fatkhudinova NL, Osidak EO, Domogatsky SP, Goldstein DV.

Stomatologiia (Mosk). 2018;97(3):7-13. doi: 10.17116/stomat20189737. Russian.


Educational Case: Cervical Neoplasia: HPV and Its Link to Cancer.

Kim T, Khader SN, Goldstein DY.

Acad Pathol. 2018 Jun 17;5:2374289518770651. doi: 10.1177/2374289518770651. eCollection 2018 Jan-Dec.


Radiologic-Pathologic Correlation of Extranodal Extension in Patients With Squamous Cell Carcinoma of the Oral Cavity: Implications for Future Editions of the TNM Classification.

Almulla A, Noel CW, Lu L, Xu W, O'Sullivan B, Goldstein DP, Hope A, Perez-Ordonez B, Weinreb I, Irish J, Gullane P, Chepeha D, Tong L, Yu E, Huang SH.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):698-708. doi: 10.1016/j.ijrobp.2018.05.020. Epub 2018 May 17.


Tuberculous Uveitis Presenting with a Bullous Exudative Retinal Detachment: A Case Report and Systematic Literature Review.

Song JH, Koreishi AF, Goldstein DA.

Ocul Immunol Inflamm. 2018 Jul 3:1-12. doi: 10.1080/09273948.2018.1485958. [Epub ahead of print]


Bloodstream infections in mechanical circulatory support device recipients in the International Society of Heart and Lung Transplantation Mechanically Assisted Circulation Support Registry: Epidemiology, risk factors, and mortality.

Aslam S, Xie R, Cowger J, Kirklin JK, Chu VH, Schueler S, de By T, Gould K, Morrissey O, Lund LH, Martin S, Goldstein D, Hannan M.

J Heart Lung Transplant. 2018 Aug;37(8):1013-1020. doi: 10.1016/j.healun.2018.04.006. Epub 2018 Apr 25.


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