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Items: 1 to 50 of 210

1.

The effects of two weeks of recombinant growth hormone administration on the response of IGF-I and N-terminal pro-peptide of collagen type III (P-III-NP) during a single bout of high resistance exercise in resistance trained young men.

Velloso CP, Aperghis M, Godfrey R, Blazevich AJ, Bartlett C, Cowan D, Holt RI, Bouloux P, Harridge SD, Goldspink G.

Growth Horm IGF Res. 2013 Jun;23(3):76-80. doi: 10.1016/j.ghir.2013.01.002. Epub 2013 Feb 19.

PMID:
23433656
2.

Mechano-Growth Factor: an important cog or a loose screw in the repair machinery?

Zabłocka B, Goldspink PH, Goldspink G, Górecki DC.

Front Endocrinol (Lausanne). 2012 Nov 1;3:131. doi: 10.3389/fendo.2012.00131. eCollection 2012. No abstract available.

3.

Age-related loss of muscle mass and strength.

Goldspink G.

J Aging Res. 2012;2012:158279. doi: 10.1155/2012/158279. Epub 2012 Mar 8.

4.

Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages.

Kandalla PK, Goldspink G, Butler-Browne G, Mouly V.

Mech Ageing Dev. 2011 Apr;132(4):154-62. doi: 10.1016/j.mad.2011.02.007. Epub 2011 Feb 25.

PMID:
21354439
5.

Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. Counterpoint: IGF is not the major physiological regulator of muscle mass.

Flueck M, Goldspink G.

J Appl Physiol (1985). 2010 Jun;108(6):1821-3; discussion 1823-4; author reply 1833. doi: 10.1152/japplphysiol.01246.2009a. No abstract available.

6.

Growth factors, muscle function, and doping.

Goldspink G, Wessner B, Tschan H, Bachl N.

Endocrinol Metab Clin North Am. 2010 Mar;39(1):169-81, xi. doi: 10.1016/j.ecl.2009.11.001.

PMID:
20122457
7.

Therapeutic use of growth factors in the musculoskeletal system in sports-related injuries.

Bachl N, Derman W, Engebretsen L, Goldspink G, Kinzlbauer M, Tschan H, Volpi P, Venter D, Wessner B.

J Sports Med Phys Fitness. 2009 Dec;49(4):346-57. Review.

PMID:
20087293
8.

High-throughput ultra-high-performance liquid chromatography/tandem mass spectrometry quantitation of insulin-like growth factor-I and leucine-rich alpha-2-glycoprotein in serum as biomarkers of recombinant human growth hormone administration.

Kay RG, Barton C, Velloso CP, Brown PR, Bartlett C, Blazevich AJ, Godfrey RJ, Goldspink G, Rees R, Ball GR, Cowan DA, Harridge SD, Roberts J, Teale P, Creaser CS.

Rapid Commun Mass Spectrom. 2009 Oct;23(19):3173-82. doi: 10.1002/rcm.4237.

PMID:
19718777
9.

A proteomic approach combining MS and bioinformatic analysis for the detection and identification of biomarkers of administration of exogenous human growth hormone in humans.

Boateng J, Kay R, Lancashire L, Brown P, Velloso C, Bouloux P, Teale P, Roberts J, Rees R, Ball G, Harridge S, Goldspink G, Creaser C.

Proteomics Clin Appl. 2009 Aug;3(8):912-22. doi: 10.1002/prca.200800190. Epub 2009 Jul 30.

PMID:
21136995
10.

Investigation of MGF mRNA expression in patients with amyotrophic lateral sclerosis using parallel in vivo and in vitro approaches.

Evans RM, Harridge SD, Velloso CP, Yang SY, Goldspink G, Orrell RW.

Amyotroph Lateral Scler. 2010;11(1-2):172-7. doi: 10.3109/17482960903089775.

PMID:
19572220
11.

Linking functional molecular variation with environmental gradients: myosin gene diversity in a crustacean broadly distributed across variable thermal environments.

Rock J, Magnay JL, Beech S, El Haj AJ, Goldspink G, Lunt DH, Whiteley NM.

Gene. 2009 May 15;437(1-2):60-70. doi: 10.1016/j.gene.2009.02.008. Epub 2009 Feb 21.

PMID:
19236910
12.

Mechano-growth factor, an IGF-I splice variant, rescues motoneurons and improves muscle function in SOD1(G93A) mice.

Riddoch-Contreras J, Yang SY, Dick JR, Goldspink G, Orrell RW, Greensmith L.

Exp Neurol. 2009 Feb;215(2):281-9. doi: 10.1016/j.expneurol.2008.10.014. Epub 2008 Nov 7.

PMID:
19038252
13.

Serum IGF-I levels and IGF-I gene splicing in muscle of healthy young males receiving rhGH.

Aperghis M, Velloso CP, Hameed M, Brothwood T, Bradley L, Bouloux PM, Harridge SD, Goldspink G.

Growth Horm IGF Res. 2009 Feb;19(1):61-7. doi: 10.1016/j.ghir.2008.07.002. Epub 2008 Sep 16.

PMID:
18799338
14.

Hypertrophy of mature Xenopus muscle fibres in culture induced by synergy of albumin and insulin.

Jaspers RT, van Beek-Harmsen BJ, Blankenstein MA, Goldspink G, Huijing PA, van der Laarse WJ.

Pflugers Arch. 2008 Oct;457(1):161-70. doi: 10.1007/s00424-008-0499-0. Epub 2008 May 21.

PMID:
18493787
15.

Growth factors, muscle function and doping.

Goldspink G, Wessner B, Bachl N.

Curr Opin Pharmacol. 2008 Jun;8(3):352-7. doi: 10.1016/j.coph.2008.02.002. Epub 2008 Mar 19. Review.

PMID:
18353722
16.

Effects of eccentric cycling exercise on IGF-I splice variant expression in the muscles of young and elderly people.

Hameed M, Toft AD, Pedersen BK, Harridge SD, Goldspink G.

Scand J Med Sci Sports. 2008 Aug;18(4):447-52. Epub 2007 Dec 7.

PMID:
18067523
17.

Role of insulin-like growth factor binding protein-4 in prevention of colon cancer.

Durai R, Yang SY, Seifalian AM, Goldspink G, Winslet MC.

World J Surg Oncol. 2007 Nov 7;5:128.

18.
19.

Loss of muscle strength during aging studied at the gene level.

Goldspink G.

Rejuvenation Res. 2007 Sep;10(3):397-405. Review.

PMID:
17822355
20.

Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction.

Carpenter V, Matthews K, Devlin G, Stuart S, Jensen J, Conaglen J, Jeanplong F, Goldspink P, Yang SY, Goldspink G, Bass J, McMahon C.

Heart Lung Circ. 2008 Feb;17(1):33-9. Epub 2007 Jun 19.

PMID:
17581790
21.

The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle.

Ates K, Yang SY, Orrell RW, Sinanan AC, Simons P, Solomon A, Beech S, Goldspink G, Lewis MP.

FEBS Lett. 2007 Jun 12;581(14):2727-32. Epub 2007 May 21.

22.
23.

Skeletal muscle IGF-I isoform expression in healthy women after isometric exercise.

Greig CA, Hameed M, Young A, Goldspink G, Noble B.

Growth Horm IGF Res. 2006 Oct-Dec;16(5-6):373-6. Epub 2006 Nov 14.

PMID:
17107821
24.

Biology of insulin-like growth factor binding protein-4 and its role in cancer (review).

Durai R, Davies M, Yang W, Yang SY, Seifalian A, Goldspink G, Winslet M.

Int J Oncol. 2006 Jun;28(6):1317-25. Review.

PMID:
16685432
25.

Impairment of IGF-I gene splicing and MGF expression associated with muscle wasting.

Goldspink G.

Int J Biochem Cell Biol. 2006 Mar;38(3):481-9. Review.

PMID:
16463438
26.

Research on mechano growth factor: its potential for optimising physical training as well as misuse in doping.

Goldspink G.

Br J Sports Med. 2005 Nov;39(11):787-8; discussion 787-8. No abstract available.

27.

A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF) in brain ischemia.

Dluzniewska J, Sarnowska A, Beresewicz M, Johnson I, Srai SK, Ramesh B, Goldspink G, Górecki DC, Zabłocka B.

FASEB J. 2005 Nov;19(13):1896-8. Epub 2005 Sep 6.

PMID:
16144956
28.

Impairment of IGF-I gene splicing and MGF expression associated with muscle wasting.

Goldspink G.

Int J Biochem Cell Biol. 2005 Oct;37(10):2012-22. Review. Erratum in: Int J Biochem Cell Biol. 2006 Mar;38(3):480. Corrected and republished in: Int J Biochem Cell Biol. 2006 Mar;38(3):481-9.

PMID:
16125110
29.

Mechanical signals, IGF-I gene splicing, and muscle adaptation.

Goldspink G.

Physiology (Bethesda). 2005 Aug;20:232-8. Review.

30.

Insulin-like growth factor-1 gene splice variants as markers of muscle damage in levator ani muscle after the first vaginal delivery.

Cortes E, te Fong LF, Hameed M, Harridge S, Maclean A, Yang SY, Reid WM, Goldspink G.

Am J Obstet Gynecol. 2005 Jul;193(1):64-70. Erratum in: Am J Obstet Gynecol. 2005 Oct;193(4):1585.

PMID:
16021060
31.

Promoter dependence of plasmid-pluronics targeted alpha galactosidase A expression in skeletal muscle of Fabry mice.

Lavigne MD, Pohlschmidt M, Novo JF, Higgins B, Alakhov V, Lochmuller H, Sakuraba H, Goldspink G, MacDermot K, Górecki DC.

Mol Ther. 2005 Nov;12(5):985-90. Epub 2005 Jun 22. No abstract available.

32.

The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence.

Davies M, Gupta S, Goldspink G, Winslet M.

Int J Colorectal Dis. 2006 Apr;21(3):201-8. Epub 2005 Jun 16. Review.

PMID:
15959790
33.

Expression of Ankrd2 in fast and slow muscles and its response to stretch are consistent with a role in slow muscle function.

Mckoy G, Hou Y, Yang SY, Vega Avelaira D, Degens H, Goldspink G, Coulton GR.

J Appl Physiol (1985). 2005 Jun;98(6):2337-43; discussion 2320. Epub 2005 Jan 27.

34.

Age-related loss of skeletal muscle function; impairment of gene expression.

Goldspink G.

J Musculoskelet Neuronal Interact. 2004 Jun;4(2):143-7. Review.

35.

The splicing of the IGF-I gene to yield different muscle growth factors.

Goldspink G, Yang SY.

Adv Genet. 2004;52:23-49. Review. No abstract available.

PMID:
15522732
36.

Growth factors and muscle ageing.

Goldspink G, Harridge SD.

Exp Gerontol. 2004 Oct;39(10):1433-8. Review.

PMID:
15501012
37.

Mechanical signals and IGF-I gene splicing in vitro in relation to development of skeletal muscle.

Cheema U, Brown R, Mudera V, Yang SY, McGrouther G, Goldspink G.

J Cell Physiol. 2005 Jan;202(1):67-75.

PMID:
15389530
38.
39.

Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures.

Ryten M, Yang SY, Dunn PM, Goldspink G, Burnstock G.

FASEB J. 2004 Sep;18(12):1404-6. Epub 2004 Jul 1.

PMID:
15231720
40.

Fish as bioreactors: transgene expression of human coagulation factor VII in fish embryos.

Hwang G, Müller F, Rahman MA, Williams DW, Murdock PJ, Pasi KJ, Goldspink G, Farahmand H, Maclean N.

Mar Biotechnol (NY). 2004 Sep-Oct;6(5):485-92. Epub 2004 Apr 29.

PMID:
15129328
41.

Different levels of neuroprotection by two insulin-like growth factor-I splice variants.

Aperghis M, Johnson IP, Cannon J, Yang SY, Goldspink G.

Brain Res. 2004 May 29;1009(1-2):213-8.

PMID:
15120599
42.
43.

Gene expression in muscle in response to exercise.

Goldspink G.

J Muscle Res Cell Motil. 2003;24(2-3):121-6. Review.

PMID:
14609023
44.

The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men.

Hameed M, Lange KH, Andersen JL, Schjerling P, Kjaer M, Harridge SD, Goldspink G.

J Physiol. 2004 Feb 15;555(Pt 1):231-40. Epub 2003 Oct 17.

45.

Differential expression of equine myosin heavy-chain mRNA and protein isoforms in a limb muscle.

Eizema K, van den Burg M, Kiri A, Dingboom EG, van Oudheusden H, Goldspink G, Weijs WA.

J Histochem Cytochem. 2003 Sep;51(9):1207-16.

PMID:
12923246
46.

Muscle satellite (stem) cell activation during local tissue injury and repair.

Hill M, Wernig A, Goldspink G.

J Anat. 2003 Jul;203(1):89-99.

47.

Skeletal muscle as an artificial endocrine tissue.

Goldspink G.

Best Pract Res Clin Endocrinol Metab. 2003 Jun;17(2):211-22. Review.

PMID:
12787548
49.

Age, diet and injury affect the survival of facial motoneurons.

Aperghis M, Johnson IP, Patel N, Khadir A, Cannon J, Goldspink G.

Neuroscience. 2003;117(1):97-104.

PMID:
12605896
50.

3-D in vitro model of early skeletal muscle development.

Cheema U, Yang SY, Mudera V, Goldspink GG, Brown RA.

Cell Motil Cytoskeleton. 2003 Mar;54(3):226-36. Erratum in: Cell Motil Cytoskeleton. 2003 Aug;55(5):278.

PMID:
12589681

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