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Items: 49

1.

Neurturin Gene Therapy Protects Parasympathetic Function to Prevent Irradiation-Induced Murine Salivary Gland Hypofunction.

Ferreira JNA, Zheng C, Lombaert IMA, Goldsmith CM, Cotrim AP, Symonds JM, Patel VN, Hoffman MP.

Mol Ther Methods Clin Dev. 2018 Feb 23;9:172-180. doi: 10.1016/j.omtm.2018.02.008. eCollection 2018 Jun 15.

2.

Effect of Tempol on the prevention of irradiation-induced mucositis in miniature pigs.

Hu L, Wang Y, Cotrim AP, Zhu Z, Gao R, Zheng C, Goldsmith CM, Jin L, Zhang C, Mitchell JB, Baum BJ, Wang S.

Oral Dis. 2017 Sep;23(6):801-808. doi: 10.1111/odi.12667. Epub 2017 Apr 27.

PMID:
28326646
3.

Late responses to adenoviral-mediated transfer of the aquaporin-1 gene for radiation-induced salivary hypofunction.

Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Billings ME, Goldsmith CM, Tandon M, Helmerhorst EJ, Catalán MA, Danielides SJ, Perez P, Nikolov NP, Chiorini JA, Melvin JE, Oppenheim FG, Illei GG, Baum BJ.

Gene Ther. 2017 Mar;24(3):176-186. doi: 10.1038/gt.2016.87. Epub 2016 Dec 20.

4.

Gene Therapy of Salivary Diseases.

Baum BJ, Afione S, Chiorini JA, Cotrim AP, Goldsmith CM, Zheng C.

Methods Mol Biol. 2017;1537:107-123.

5.

Immune reactivity after adenoviral-mediated aquaporin-1 cDNA transfer to human parotid glands.

Alevizos I, Zheng C, Cotrim AP, Goldsmith CM, McCullagh L, Berkowitz T, Strobl SL, Malyguine A, Kopp WC, Chiorini JA, Nikolov NP, Neely M, Illei GG, Baum BJ.

Oral Dis. 2017 Apr;23(3):337-346. doi: 10.1111/odi.12614. Epub 2017 Feb 8.

6.

Adenovirus-mediated hAQP1 expression in irradiated mouse salivary glands causes recovery of saliva secretion by enhancing acinar cell volume decrease.

Teos LY, Zheng CY, Liu X, Swaim WD, Goldsmith CM, Cotrim AP, Baum BJ, Ambudkar IS.

Gene Ther. 2016 Jul;23(7):572-9. doi: 10.1038/gt.2016.29. Epub 2016 Mar 11.

7.

Persistence of hAQP1 expression in human salivary gland cells following AdhAQP1 transduction is associated with a lack of methylation of hCMV promoter.

Zheng C, Baum BJ, Liu X, Goldsmith CM, Perez P, Jang SI, Cotrim AP, McCullagh L, Ambudkar IS, Alevizos I.

Gene Ther. 2015 Sep;22(9):758-66. doi: 10.1038/gt.2015.55. Epub 2015 Jul 16.

8.

STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.

Ong HL, de Souza LB, Zheng C, Cheng KT, Liu X, Goldsmith CM, Feske S, Ambudkar IS.

Sci Signal. 2015 Jan 13;8(359):ra3. doi: 10.1126/scisignal.2005748. Erratum in: Sci Signal. 2015 Feb 3;8(362):er2.

9.

AdLTR2EF1α-FGF2-mediated prevention of fractionated irradiation-induced salivary hypofunction in swine.

Guo L, Gao R, Xu J, Jin L, Cotrim AP, Yan X, Zheng C, Goldsmith CM, Shan Z, Hai B, Zhou J, Zhang C, Baum BJ, Wang S.

Gene Ther. 2014 Oct;21(10):866-73. doi: 10.1038/gt.2014.63. Epub 2014 Jul 17.

PMID:
25030610
10.

Toward gene therapy for growth hormone deficiency via salivary gland expression of growth hormone.

Racz GZ, Zheng C, Goldsmith CM, Baum BJ, Cawley NX.

Oral Dis. 2015 Mar;21(2):149-55. doi: 10.1111/odi.12217. Epub 2014 Jan 13.

11.

Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction.

Baum BJ, Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, Burbelo PD, Citrin DE, Mitchell JB, Nottingham LK, Rudy SF, Van Waes C, Whatley MA, Brahim JS, Chiorini JA, Danielides S, Turner RJ, Patronas NJ, Chen CC, Nikolov NP, Illei GG.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19403-7. doi: 10.1073/pnas.1210662109. Epub 2012 Nov 5.

12.

Transgenic α-1-antitrypsin secreted into the bloodstream from salivary glands is biologically active.

Perez P, Adriaansen J, Goldsmith CM, Zheng C, Baum BJ.

Oral Dis. 2011 Jul;17(5):476-83. doi: 10.1111/j.1601-0825.2010.01775.x. Epub 2010 Dec 2.

13.

AAV2-mediated transfer of the human aquaporin-1 cDNA restores fluid secretion from irradiated miniature pig parotid glands.

Gao R, Yan X, Zheng C, Goldsmith CM, Afione S, Hai B, Xu J, Zhou J, Zhang C, Chiorini JA, Baum BJ, Wang S.

Gene Ther. 2011 Jan;18(1):38-42. doi: 10.1038/gt.2010.128. Epub 2010 Sep 30.

14.

Gene therapy of salivary diseases.

Baum BJ, Adriaansen J, Cotrim AP, Goldsmith CM, Perez P, Qi S, Rowzee AM, Zheng C.

Methods Mol Biol. 2010;666:3-20. doi: 10.1007/978-1-60761-820-1_1.

PMID:
20717774
15.

Convenient and reproducible in vivo gene transfer to mouse parotid glands.

Zheng C, Shinomiya T, Goldsmith CM, Di Pasquale G, Baum BJ.

Oral Dis. 2011 Jan;17(1):77-82. doi: 10.1111/j.1601-0825.2010.01707.x.

16.

Development of a gene transfer-based treatment for radiation-induced salivary hypofunction.

Baum BJ, Zheng C, Alevizos I, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, McDermott N, Chiorini JA, Nikolov NP, Illei GG.

Oral Oncol. 2010 Jan;46(1):4-8. doi: 10.1016/j.oraloncology.2009.09.004. Epub 2009 Nov 4. Review.

17.

Long-term transduction of miniature pig parotid glands using serotype 2 adeno-associated viral vectors.

Hai B, Yan X, Voutetakis A, Zheng C, Cotrim AP, Shan Z, Ding G, Zhang C, Xu J, Goldsmith CM, Afione S, Chiorini JA, Baum BJ, Wang S.

J Gene Med. 2009 Jun;11(6):506-14. doi: 10.1002/jgm.1319.

18.

Aquaporin-1 gene transfer to correct radiation-induced salivary hypofunction.

Baum BJ, Zheng C, Cotrim AP, McCullagh L, Goldsmith CM, Brahim JS, Atkinson JC, Turner RJ, Liu S, Nikolov N, Illei GG.

Handb Exp Pharmacol. 2009;(190):403-18. doi: 10.1007/978-3-540-79885-9_20. Review.

19.

Transient TWEAK overexpression leads to a general salivary epithelial cell proliferation.

Sugito T, Mineshiba F, Zheng C, Cotrim AP, Goldsmith CM, Baum BJ.

Oral Dis. 2009 Jan;15(1):76-81. doi: 10.1111/j.1601-0825.2008.01474.x. Epub 2008 Sep 29.

20.

Differential sorting of human parathyroid hormone after transduction of mouse and rat salivary glands.

Adriaansen J, Perez P, Goldsmith CM, Zheng C, Baum BJ.

Hum Gene Ther. 2008 Oct;19(10):1021-8. doi: 10.1089/hum.2008.079.

21.

Gender differences in serotype 2 adeno-associated virus biodistribution after administration to rodent salivary glands.

Voutetakis A, Zheng C, Wang J, Goldsmith CM, Afione S, Chiorini JA, Wenk ML, Vallant M, Irwin RD, Baum BJ.

Hum Gene Ther. 2007 Nov;18(11):1109-18.

PMID:
17939749
22.

Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands.

Nandula SR, Amarnath S, Molinolo A, Bandyopadhyay BC, Hall B, Goldsmith CM, Zheng C, Larsson J, Sreenath T, Chen W, Ambudkar IS, Karlsson S, Baum BJ, Kulkarni AB.

Arthritis Rheum. 2007 Jun;56(6):1798-805.

23.

Adeno-associated virus serotype 2-mediated gene transfer to the parotid glands of nonhuman primates.

Voutetakis A, Zheng C, Mineshiba F, Cotrim AP, Goldsmith CM, Schmidt M, Afione S, Roescher N, Metzger M, Eckhaus MA, Chiorini JA, Dunbar CE, Donahue RE, Baum BJ.

Hum Gene Ther. 2007 Feb;18(2):142-50.

PMID:
17328682
24.

Toxicity and biodistribution of a first-generation recombinant adenoviral vector, encoding aquaporin-1, after retroductal delivery to a single rat submandibular gland.

Zheng C, Goldsmith CM, Mineshiba F, Chiorini JA, Kerr A, Wenk ML, Vallant M, Irwin RD, Baum BJ.

Hum Gene Ther. 2006 Nov;17(11):1122-33.

PMID:
17069536
25.

Toxicity and biodistribution of a first-generation recombinant adenoviral vector, in the presence of hydroxychloroquine, following retroductal delivery to a single rat submandibular gland.

Zheng C, Voutetakis A, Kok MR, Goldsmith CM, Smith GB, Elmore S, Nyska A, Vallant M, Irwin RD, Baum BJ.

Oral Dis. 2006 Mar;12(2):137-44.

PMID:
16476034
26.

Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction.

Baum BJ, Zheng C, Cotrim AP, Goldsmith CM, Atkinson JC, Brahim JS, Chiorini JA, Voutetakis A, Leakan RA, Van Waes C, Mitchell JB, Delporte C, Wang S, Kaminsky SM, Illei GG.

Biochim Biophys Acta. 2006 Aug;1758(8):1071-7. Epub 2005 Dec 5. Review.

27.

Endogenous osteonectin/SPARC/BM-40 expression inhibits MDA-MB-231 breast cancer cell metastasis.

Koblinski JE, Kaplan-Singer BR, VanOsdol SJ, Wu M, Engbring JA, Wang S, Goldsmith CM, Piper JT, Vostal JG, Harms JF, Welch DR, Kleinman HK.

Cancer Res. 2005 Aug 15;65(16):7370-7.

28.

Partial redirection of transgenic human growth hormone secretion from rat salivary glands.

Wang J, Cawley NX, Voutetakis A, Rodriguez YM, Goldsmith CM, Nieman LK, Hoque AT, Frank SJ, Snell CR, Loh YP, Baum BJ.

Hum Gene Ther. 2005 May;16(5):571-83.

PMID:
15916482
29.

Primary culture of polarized human salivary epithelial cells for use in developing an artificial salivary gland.

Tran SD, Wang J, Bandyopadhyay BC, Redman RS, Dutra A, Pak E, Swaim WD, Gerstenhaber JA, Bryant JM, Zheng C, Goldsmith CM, Kok MR, Wellner RB, Baum BJ.

Tissue Eng. 2005 Jan-Feb;11(1-2):172-81.

PMID:
15738672
30.

Increased fluid secretion after adenoviral-mediated transfer of the human aquaporin-1 cDNA to irradiated miniature pig parotid glands.

Shan Z, Li J, Zheng C, Liu X, Fan Z, Zhang C, Goldsmith CM, Wellner RB, Baum BJ, Wang S.

Mol Ther. 2005 Mar;11(3):444-51.

31.

A recombinant adenoviral vector encoding functional vasoactive intestinal peptide.

Lodde BM, Delporte C, Goldsmith CM, Tak PP, Baum BJ.

Biochem Biophys Res Commun. 2004 Jun 18;319(1):189-92.

PMID:
15158460
32.

Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics.

Voutetakis A, Kok MR, Zheng C, Bossis I, Wang J, Cotrim AP, Marracino N, Goldsmith CM, Chiorini JA, Loh YP, Nieman LK, Baum BJ.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3053-8. Epub 2004 Feb 20.

33.

Developing a convenient large animal model for gene transfer to salivary glands in vivo.

Li J, Zheng C, Zhang X, Liu X, Zhang C, Goldsmith CM, Baum BJ, Wang S.

J Gene Med. 2004 Jan;6(1):55-63.

PMID:
14716677
34.

Advances in vector-mediated gene transfer.

Baum BJ, Goldsmith CM, Kok MR, Lodde BM, van Mello NM, Voutetakis A, Wang J, Yamano S, Zheng C.

Immunol Lett. 2003 Dec 15;90(2-3):145-9. Review. Erratum in: Immunol Lett. 2004 Feb 15;91(2-3):255.

PMID:
14687716
35.

Expression of the aquaporin 8 water channel in a rat salivary epithelial cell.

Hoque AT, Yamano S, Liu X, Swaim WD, Goldsmith CM, Delporte C, Baum BJ.

J Cell Physiol. 2002 Jun;191(3):336-41.

PMID:
12012329
36.

Recombinant adeno-associated virus serotype 2 vectors mediate stable interleukin 10 secretion from salivary glands into the bloodstream.

Yamano S, Huang LY, Ding C, Chiorini JA, Goldsmith CM, Wellner RB, Golding B, Kotin RM, Scott DE, Baum BJ.

Hum Gene Ther. 2002 Jan 20;13(2):287-98.

PMID:
11812284
37.

Using HSV-thymidine kinase for safety in an allogeneic salivary graft cell line.

Aframian DJ, Zheng C, Goldsmith CM, Nikolovski J, Cukierman E, Yamada KM, Mooney DJ, Birkedal-Hansen H, Baum BJ.

Tissue Eng. 2001 Aug;7(4):405-13.

38.

Insulin-like growth factor-I (IGF-I) receptor activation rescues UV-damaged cells through a p38 signaling pathway. Potential role of the IGF-I receptor in DNA repair.

Héron-Milhavet L, Karas M, Goldsmith CM, Baum BJ, LeRoith D.

J Biol Chem. 2001 May 25;276(21):18185-92. Epub 2001 Mar 12.

39.

Cationic liposome-mediated gene transfer to rat salivary epithelial cells in vitro and in vivo.

Baccaglini L, Shamsul Hoque AT, Wellner RB, Goldsmith CM, Redman RS, Sankar V, Kingman A, Barnhart KM, Wheeler CJ, Baum BJ.

J Gene Med. 2001 Jan-Feb;3(1):82-90.

PMID:
11269339
40.

Evidence that aquaporin-8 is located in the basolateral membrane of rat submandibular gland acinar cells.

Wellner RB, Hoque AT, Goldsmith CM, Baum BJ.

Pflugers Arch. 2000 Nov;441(1):49-56.

PMID:
11205061
41.

Salivary glands as a model for craniofacial applications of gene transfer.

Baum BJ, Goldsmith CM, Hoque AT, Wellner RB, Baccaglini L, Ding C, Yamano S, Zheng C, Aframian DJ, Zheng C, Aframian DJ, O'Connell BC.

Int J Oral Maxillofac Surg. 2000 Jun;29(3):163-6. Review.

PMID:
10970076
42.

Adenoviral vector cytotoxicity depends in part on the transgene encoded.

Zheng C, Goldsmith CM, O'Connell BC, Baum BJ.

Biochem Biophys Res Commun. 2000 Aug 11;274(3):767-71.

PMID:
10924352
43.

Polarized secretion of transgene products from salivary glands in vivo.

Baum BJ, Berkman ME, Marmary Y, Goldsmith CM, Baccaglini L, Wang S, Wellner RB, Hoque AT, Atkinson JC, Yamagishi H, Kagami H, Parlow AF, Chao J.

Hum Gene Ther. 1999 Nov 20;10(17):2789-97.

PMID:
10584925
44.

Construction and in vivo efficacy of a replication-deficient recombinant adenovirus encoding murine growth hormone.

Marmary Y, Parlow AF, Goldsmith CM, He X, Wellner RB, Satomura K, Kriete MF, Robey PG, Nieman LK, Baum BJ.

Endocrinology. 1999 Jan;140(1):260-5.

PMID:
9886833
45.

Relationship between adenovirus-mediated aquaporin 1 expression and fluid movement across epithelial cells.

Delporte C, Hoque AT, Kulakusky JA, Braddon VR, Goldsmith CM, Wellner RB, Baum BJ.

Biochem Biophys Res Commun. 1998 May 29;246(3):584-8.

PMID:
9618254
46.

Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands.

He X, Goldsmith CM, Marmary Y, Wellner RB, Parlow AF, Nieman LK, Baum BJ.

Gene Ther. 1998 Apr;5(4):537-41.

47.

Effect of standing versus sitting position on spirometric indices in healthy subjects.

Lalloo UG, Becklake MR, Goldsmith CM.

Respiration. 1991;58(3-4):122-5.

PMID:
1745842
48.

LYMPHOCYTES IN URINE AS AN AID IN THE EARLY DETECTION OF RENAL HOMOGRAFT REJECTION.

KAUFFMAN HM Jr, CLARK RF, MAGEE JH, RITTENBURY MS, GOLDSMITH CM, PROUT GR Jr, HUME DM.

Surg Gynecol Obstet. 1964 Jul;119:25-36. No abstract available.

PMID:
14179347
49.

Hepatic coma induced by high protein therapy and by diarrhea; two case reports.

GOLDSMITH CM, CHAPIN MA.

J Maine Med Assoc. 1958 Mar;49(3):80-4. No abstract available.

PMID:
13514324

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