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Time for Well-Powered Controlled Prospective Studies to test a Causal Role for Herpes Viruses in Alzheimer Using Anti-Herpes Drugs.

Goldschmidt-Clermont PJ, Volinsky FG, LaRosa SP, Gilbert JR, Periçak-Vance MA.

J Gerontol A Biol Sci Med Sci. 2019 Jun 7. pii: glz150. doi: 10.1093/gerona/glz150. [Epub ahead of print]


Accelerated coronary atherosclerosis not explained by traditional risk factors in 13% of young individuals.

Head T, Henn L, Andreev VP, Herderick EE, Deo SK, Daunert S, Goldschmidt-Clermont PJ.

Am Heart J. 2019 Feb;208:47-54. doi: 10.1016/j.ahj.2018.11.005. Epub 2018 Nov 13.


KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis.

Cavallin LE, Ma Q, Naipauer J, Gupta S, Kurian M, Locatelli P, Romanelli P, Nadji M, Goldschmidt-Clermont PJ, Mesri EA.

PLoS Pathog. 2018 Jul 9;14(7):e1007175. doi: 10.1371/journal.ppat.1007175. eCollection 2018 Jul.


Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques.

Magnani DM, Rogers TF, Maness NJ, Grubaugh ND, Beutler N, Bailey VK, Gonzalez-Nieto L, Gutman MJ, Pedreño-Lopez N, Kwal JM, Ricciardi MJ, Myers TA, Julander JG, Bohm RP, Gilbert MH, Schiro F, Aye PP, Blair RV, Martins MA, Falkenstein KP, Kaur A, Curry CL, Kallas EG, Desrosiers RC, Goldschmidt-Clermont PJ, Whitehead SS, Andersen KG, Bonaldo MC, Lackner AA, Panganiban AT, Burton DR, Watkins DI.

Nat Commun. 2018 Apr 24;9(1):1624. doi: 10.1038/s41467-018-04056-4.


The Aging Risk and Atherosclerosis: A Fresh Look at Arterial Homeostasis.

Head T, Daunert S, Goldschmidt-Clermont PJ.

Front Genet. 2017 Dec 14;8:216. doi: 10.3389/fgene.2017.00216. eCollection 2017. Review.


Coronary collateralization shows sex and racial-ethnic differences in obstructive artery disease patients.

Liu Z, Pericak-Vance MA, Goldschmidt-Clermont P, Seo D, Wang L, Rundek T, Beecham GW.

PLoS One. 2017 Oct 10;12(10):e0183836. doi: 10.1371/journal.pone.0183836. eCollection 2017.


Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Tompkins BA, DiFede DL, Khan A, Landin AM, Schulman IH, Pujol MV, Heldman AW, Miki R, Goldschmidt-Clermont PJ, Goldstein BJ, Mushtaq M, Levis-Dusseau S, Byrnes JJ, Lowery M, Natsumeda M, Delgado C, Saltzman R, Vidro-Casiano M, Da Fonseca M, Golpanian S, Premer C, Medina A, Valasaki K, Florea V, Anderson E, El-Khorazaty J, Mendizabal A, Green G, Oliva AA, Hare JM.

J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1513-1522. doi: 10.1093/gerona/glx137.


Twenty-First Century Diseases: Commonly Rare and Rarely Common?

Daunert S, Sittampalam GS, Goldschmidt-Clermont PJ.

Antioxid Redox Signal. 2017 Sep 20;27(9):511-516. doi: 10.1089/ars.2017.7065. Epub 2017 Jul 5.


Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty.

Golpanian S, DiFede DL, Khan A, Schulman IH, Landin AM, Tompkins BA, Heldman AW, Miki R, Goldstein BJ, Mushtaq M, Levis-Dusseau S, Byrnes JJ, Lowery M, Natsumeda M, Delgado C, Saltzman R, Vidro-Casiano M, Pujol MV, Da Fonseca M, Oliva AA Jr, Green G, Premer C, Medina A, Valasaki K, Florea V, Anderson E, El-Khorazaty J, Mendizabal A, Goldschmidt-Clermont PJ, Hare JM.

J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1505-1512. doi: 10.1093/gerona/glx056.


Utility of blood pressure genetic risk score in admixed Hispanic samples.

Beecham AH, Wang L, Vasudeva N, Liu Z, Dong C, Goldschmidt-Clermont PJ, Pericak-Vance MA, Rundek T, Seo D, Blanton SH, Sacco RL, Beecham GW.

J Hum Hypertens. 2016 Dec;30(12):772-777. doi: 10.1038/jhh.2016.29. Epub 2016 Jun 2.


Rationale and design of the allogeneiC human mesenchymal stem cells (hMSC) in patients with aging fRAilTy via intravenoUS delivery (CRATUS) study: A phase I/II, randomized, blinded and placebo controlled trial to evaluate the safety and potential efficacy of allogeneic human mesenchymal stem cell infusion in patients with aging frailty.

Golpanian S, DiFede DL, Pujol MV, Lowery MH, Levis-Dusseau S, Goldstein BJ, Schulman IH, Longsomboon B, Wolf A, Khan A, Heldman AW, Goldschmidt-Clermont PJ, Hare JM.

Oncotarget. 2016 Mar 15;7(11):11899-912. doi: 10.18632/oncotarget.7727.


Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS.

Cavallin LE, Goldschmidt-Clermont P, Mesri EA.

PLoS Pathog. 2014 Jul 10;10(7):e1004154. doi: 10.1371/journal.ppat.1004154. eCollection 2014 Jul. Review. No abstract available.


Cardiac performance, biomarkers and gene expression studies in previously sedentary men participating in half-marathon training.

Vance DD, Chen GL, Stoutenberg M, Myerburg RJ, Jacobs K, Nathanson L, Perry A, Seo D, Goldschmidt-Clermont PJ, Rampersaud E.

BMC Sports Sci Med Rehabil. 2014 Feb 19;6(1):6. doi: 10.1186/2052-1847-6-6.


Molecular studies and therapeutic targeting of Kaposi's sarcoma herpesvirus (KSHV/HHV-8) oncogenesis.

Mesri EA, Cavallin LE, Ashlock BM, Leung HJ, Ma Q, Goldschmidt-Clermont PJ.

Immunol Res. 2013 Dec;57(1-3):159-65. doi: 10.1007/s12026-013-8458-z. Review.


Epigenetic regulation of COL15A1 in smooth muscle cell replicative aging and atherosclerosis.

Connelly JJ, Cherepanova OA, Doss JF, Karaoli T, Lillard TS, Markunas CA, Nelson S, Wang T, Ellis PD, Langford CF, Haynes C, Seo DM, Goldschmidt-Clermont PJ, Shah SH, Kraus WE, Hauser ER, Gregory SG.

Hum Mol Genet. 2013 Dec 20;22(25):5107-20. doi: 10.1093/hmg/ddt365. Epub 2013 Aug 2.


Discrete event simulation model of sudden cardiac death predicts high impact of preventive interventions.

Andreev VP, Head T, Johnson N, Deo SK, Daunert S, Goldschmidt-Clermont PJ.

Sci Rep. 2013;3:1771. doi: 10.1038/srep01771.


Genomic signatures of a global fitness index in a multi-ethnic cohort of women.

Rampersaud E, Nathanson L, Farmer J, Meshbane K, Belton RL, Dressen A, Cuccaro M, Musto A, Daunert S, Deo S, Hudson N, Vance JM, Seo D, Mendez A, Dykxhoorn DM, Pericak-Vance MA, Goldschmidt-Clermont PJ.

Ann Hum Genet. 2013 Mar;77(2):147-57. doi: 10.1111/ahg.12006. Epub 2013 Jan 7.


Defining a molecular portrait of physical fitness.

Clouse A, Deo S, Rampersaud E, Farmer J, Goldschmidt-Clermont PJ, Daunert S.

Anal Bioanal Chem. 2013 Jan;405(1):21-6. doi: 10.1007/s00216-012-6533-2. No abstract available.


Notch activation induces endothelial cell senescence and pro-inflammatory response: implication of Notch signaling in atherosclerosis.

Liu ZJ, Tan Y, Beecham GW, Seo DM, Tian R, Li Y, Vazquez-Padron RI, Pericak-Vance M, Vance JM, Goldschmidt-Clermont PJ, Livingstone AS, Velazquez OC.

Atherosclerosis. 2012 Dec;225(2):296-303. doi: 10.1016/j.atherosclerosis.2012.04.010. Epub 2012 May 18.


MicroRNA-10A* and MicroRNA-21 modulate endothelial progenitor cell senescence via suppressing high-mobility group A2.

Zhu S, Deng S, Ma Q, Zhang T, Jia C, Zhuo D, Yang F, Wei J, Wang L, Dykxhoorn DM, Hare JM, Goldschmidt-Clermont PJ, Dong C.

Circ Res. 2013 Jan 4;112(1):152-64. doi: 10.1161/CIRCRESAHA.112.280016. Epub 2012 Oct 16.


A role for virally induced reactive oxygen species in Kaposi's sarcoma herpesvirus tumorigenesis.

Ma Q, Cavallin LE, Leung HJ, Chiozzini C, Goldschmidt-Clermont PJ, Mesri EA.

Antioxid Redox Signal. 2013 Jan 1;18(1):80-90. doi: 10.1089/ars.2012.4584. Epub 2012 Aug 20.


Heartache and heartbreak--the link between depression and cardiovascular disease.

Nemeroff CB, Goldschmidt-Clermont PJ.

Nat Rev Cardiol. 2012 Sep;9(9):526-39. doi: 10.1038/nrcardio.2012.91. Epub 2012 Jun 26. Review.


Atherosclerosis, inflammation, genetics, and stem cells: 2012 update.

Goldschmidt-Clermont PJ, Dong C, Seo DM, Velazquez OC.

Curr Atheroscler Rep. 2012 Jun;14(3):201-10. doi: 10.1007/s11883-012-0244-1. Review.


Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5.

Nolan DK, Sutton B, Haynes C, Johnson J, Sebek J, Dowdy E, Crosslin D, Crossman D, Sketch MH Jr, Granger CB, Seo D, Goldschmidt-Clermont P, Kraus WE, Gregory SG, Hauser ER, Shah SH.

BMC Genet. 2012 Feb 27;13:12. doi: 10.1186/1471-2156-13-12.


Will periodic intravenous injections of conditioned bone marrow cells effectively reduce atherosclerosis?

Song X, Ma Q, Liu X, Seo P, Herderick E, Webster K, Goldschmidt-Clermont PJ, Seo D.

Antioxid Redox Signal. 2012 Jan 1;16(1):85-91. doi: 10.1089/ars.2011.4139. Epub 2011 Sep 22.


Origin of neointimal cells in arteriovenous fistulae: bone marrow, artery, or the vein itself?

Skartsis N, Manning E, Wei Y, Velazquez OC, Liu ZJ, Goldschmidt-Clermont PJ, Salman LH, Asif A, Vazquez-Padron RI.

Semin Dial. 2011 Mar-Apr;24(2):242-8. doi: 10.1111/j.1525-139X.2011.00870.x.


An essential role for diet in exercise-mediated protection against dyslipidemia, inflammation and atherosclerosis in ApoE⁻/⁻ mice.

Cesar L, Suarez SV, Adi J, Adi N, Vazquez-Padron R, Yu H, Ma Q, Goldschmidt-Clermont PJ, Agatston A, Kurlansky P, Webster KA.

PLoS One. 2011 Feb 16;6(2):e17263. doi: 10.1371/journal.pone.0017263.


Polymorphic variants in tenascin-C (TNC) are associated with atherosclerosis and coronary artery disease.

Minear MA, Crosslin DR, Sutton BS, Connelly JJ, Nelson SC, Gadson-Watson S, Wang T, Seo D, Vance JM, Sketch MH Jr, Haynes C, Goldschmidt-Clermont PJ, Shah SH, Kraus WE, Hauser ER, Gregory SG.

Hum Genet. 2011 Jun;129(6):641-54. doi: 10.1007/s00439-011-0959-z. Epub 2011 Feb 5.


In the aftermath of tragedy: medical and psychiatric consequences.

Nemeroff CB, Goldschmidt-Clermont PJ.

Acad Psychiatry. 2011 Jan-Feb;35(1):4-7. doi: 10.1176/appi.ap.35.1.4. No abstract available.


Inflammation, stem cells and atherosclerosis genetics.

Goldschmidt-Clermont PJ, Seo DM, Wang L, Beecham GW, Liu ZJ, Vazquez-Padron RI, Dong C, Hare JM, Kapiloff MS, Bishopric NH, Pericak-Vance M, Vance JM, Velazquez OC.

Curr Opin Mol Ther. 2010 Dec;12(6):712-23. Review.


Journey in antithrombotic strategies for ST-elevation myocardial infarction.

Chen GL, Dong C, Goldschmidt-Clermont PJ.

Crit Pathw Cardiol. 2010 Dec;9(4):235-42. doi: 10.1097/HPC.0b013e31820303ff. Review.


Engineering healthcare as a service system.

Tien JM, Goldschmidt-Clermont PJ.

Stud Health Technol Inform. 2010;153:277-97.


Human umbilical cord blood endothelial progenitor cells decrease vein graft neointimal hyperplasia in SCID mice.

Zhu S, Malhotra A, Zhang L, Deng S, Zhang T, Freedman NJ, Storms R, Peppel K, Goldschmidt-Clermont PJ, Dong C.

Atherosclerosis. 2010 Sep;212(1):63-9. doi: 10.1016/j.atherosclerosis.2010.04.018. Epub 2010 Apr 21.


Genomics of premature atherosclerotic vascular disease.

Seo D, Goldschmidt-Clermont P, Velazquez O, Beecham G.

Curr Atheroscler Rep. 2010 May;12(3):187-93. doi: 10.1007/s11883-010-0104-9. Review. Erratum in: Curr Atheroscler Rep. 2010 Sep;12(5):355. Goldschidt-Clermont, Pascal [corrected to Goldschmidt-Clermont, Pascal].


Vascular hypertrophy-associated hypertension of profilin1 transgenic mouse model leads to functional remodeling of peripheral arteries.

Hassona MD, Abouelnaga ZA, Elnakish MT, Awad MM, Alhaj M, Goldschmidt-Clermont PJ, Hassanain H.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H2112-20. doi: 10.1152/ajpheart.00016.2010. Epub 2010 Apr 16.


Rapid medical relief--Project Medishare and the Haitian earthquake.

Ginzburg E, O'Neill WW, Goldschmidt-Clermont PJ, de Marchena E, Pust D, Green BA.

N Engl J Med. 2010 Mar 11;362(10):e31. doi: 10.1056/NEJMp1002026. Epub 2010 Feb 24. No abstract available.


Endothelial progenitor cells (EPCs) mobilized and activated by neurotrophic factors may contribute to pathologic neovascularization in diabetic retinopathy.

Liu X, Li Y, Liu Y, Luo Y, Wang D, Annex BH, Goldschmidt-Clermont PJ.

Am J Pathol. 2010 Jan;176(1):504-15. doi: 10.2353/ajpath.2010.081152. Epub 2009 Nov 30.


Perspective: Autonomic care systems for hospitalized patients.

Goldschmidt-Clermont PJ, Dong C, Rhodes NM, McNeill DB, Adams MB, Gilliss CL, Cuffe MS, Califf RM, Peterson ED, Lubarsky DA.

Acad Med. 2009 Dec;84(12):1727-31. doi: 10.1097/ACM.0b013e3181bf9bfd.


A novel mouse model of in-stent restenosis.

Rodriguez-Menocal L, Wei Y, Pham SM, St-Pierre M, Li S, Webster K, Goldschmidt-Clermont P, Vazquez-Padron RI.

Atherosclerosis. 2010 Apr;209(2):359-66. doi: 10.1016/j.atherosclerosis.2009.09.071. Epub 2009 Oct 6.


Gene expression patterns in peripheral blood correlate with the extent of coronary artery disease.

Sinnaeve PR, Donahue MP, Grass P, Seo D, Vonderscher J, Chibout SD, Kraus WE, Sketch M Jr, Nelson C, Ginsburg GS, Goldschmidt-Clermont PJ, Granger CB.

PLoS One. 2009 Sep 14;4(9):e7037. doi: 10.1371/journal.pone.0007037.


Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma.

Ma Q, Cavallin LE, Yan B, Zhu S, Duran EM, Wang H, Hale LP, Dong C, Cesarman E, Mesri EA, Goldschmidt-Clermont PJ.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8683-8. doi: 10.1073/pnas.0812688106. Epub 2009 May 8.


The paraoxonase gene family and atherosclerosis.

Seo D, Goldschmidt-Clermont P.

Curr Atheroscler Rep. 2009 May;11(3):182-7. Review.


Common endothelial progenitor cell assays identify discrete endothelial progenitor cell populations.

Povsic TJ, Zavodni KL, Vainorius E, Kherani JF, Goldschmidt-Clermont PJ, Peterson ED.

Am Heart J. 2009 Feb;157(2):335-44. doi: 10.1016/j.ahj.2008.10.010. Epub 2008 Dec 9.


Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis.

Crosslin DR, Shah SH, Nelson SC, Haynes CS, Connelly JJ, Gadson S, Goldschmidt-Clermont PJ, Vance JM, Rose J, Granger CB, Seo D, Gregory SG, Kraus WE, Hauser ER.

Hum Genet. 2009 Mar;125(2):217-29. doi: 10.1007/s00439-008-0619-0. Epub 2009 Jan 8.


Endothelial progenitor cells: markers of vascular reparative capacity.

Povsic TJ, Goldschmidt-Clermont PJ.

Ther Adv Cardiovasc Dis. 2008 Jun;2(3):199-213. doi: 10.1177/1753944708093412. Review.


Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.

Shah SH, Freedman NJ, Zhang L, Crosslin DR, Stone DH, Haynes C, Johnson J, Nelson S, Wang L, Connelly JJ, Muehlbauer M, Ginsburg GS, Crossman DC, Jones CJ, Vance J, Sketch MH, Granger CB, Newgard CB, Gregory SG, Goldschmidt-Clermont PJ, Kraus WE, Hauser ER.

PLoS Genet. 2009 Jan;5(1):e1000318. doi: 10.1371/journal.pgen.1000318. Epub 2009 Jan 2.


Transcriptional regulation of Bim by FOXO3a and Akt mediates scleroderma serum-induced apoptosis in endothelial progenitor cells.

Zhu S, Evans S, Yan B, Povsic TJ, Tapson V, Goldschmidt-Clermont PJ, Dong C.

Circulation. 2008 Nov 18;118(21):2156-65. doi: 10.1161/CIRCULATIONAHA.108.787200. Epub 2008 Nov 3.


Voluntary running suppresses proinflammatory cytokines and bone marrow endothelial progenitor cell levels in apolipoprotein-E-deficient mice.

Ajijola OA, Dong C, Herderick EE, Ma Q, Goldschmidt-Clermont PJ, Yan Z.

Antioxid Redox Signal. 2009 Jan;11(1):15-23. doi: 10.1089/ars.2008.2092.


Contrast-enhanced magnetic resonance imaging as the newest tool to detect transplant coronary artery disease.

Goldschmidt-Clermont PJ, Dong C.

J Am Coll Cardiol. 2008 Sep 30;52(14):1168-9. doi: 10.1016/j.jacc.2008.06.039. No abstract available.

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