Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 90

1.

Molecular charge associated with antiarrhythmic actions in a series of amino-2-cyclohexyl ester derivatives.

Pugsley MK, Yong SL, Goldin AL, Hayes ES, Walker MJA.

Eur J Pharmacol. 2019 Feb 5;844:241-252. doi: 10.1016/j.ejphar.2018.12.025. Epub 2018 Dec 17.

PMID:
30571955
2.

Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker.

Walker MJA, Hayes ES, Saint DA, Adaikan G, Abraham S, Goldin AL, Beatch GN, MacLeod BA, Wall RA, Pugsley MK.

Biomed Pharmacother. 2018 Oct;106:510-522. doi: 10.1016/j.biopha.2018.06.157. Epub 2018 Jul 11.

3.

Early-life febrile seizures worsen adult phenotypes in Scn1a mutants.

Dutton SBB, Dutt K, Papale LA, Helmers S, Goldin AL, Escayg A.

Exp Neurol. 2017 Jul;293:159-171. doi: 10.1016/j.expneurol.2017.03.026. Epub 2017 Apr 1.

4.

Regulation of Thalamic and Cortical Network Synchrony by Scn8a.

Makinson CD, Tanaka BS, Sorokin JM, Wong JC, Christian CA, Goldin AL, Escayg A, Huguenard JR.

Neuron. 2017 Mar 8;93(5):1165-1179.e6. doi: 10.1016/j.neuron.2017.01.031. Epub 2017 Feb 23.

5.

SCN8A encephalopathy: Research progress and prospects.

Meisler MH, Helman G, Hammer MF, Fureman BE, Gaillard WD, Goldin AL, Hirose S, Ishii A, Kroner BL, Lossin C, Mefford HC, Parent JM, Patel M, Schreiber J, Stewart R, Whittemore V, Wilcox K, Wagnon JL, Pearl PL, Vanderver A, Scheffer IE.

Epilepsia. 2016 Jul;57(7):1027-35. doi: 10.1111/epi.13422. Epub 2016 Jun 8.

6.

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

Makinson CD, Dutt K, Lin F, Papale LA, Shankar A, Barela AJ, Liu R, Goldin AL, Escayg A.

Exp Neurol. 2016 Jan;275 Pt 1:46-58. doi: 10.1016/j.expneurol.2015.09.008. Epub 2015 Sep 26.

7.

Complex genetic interactions in a mouse model of absence epilepsy.

Goldin AL, Escayg A.

Epilepsy Curr. 2015 Jan-Feb;15(1):50-1. doi: 10.5698/1535-7597-15.1.50. No abstract available.

8.

The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant.

Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H.

Neurotherapeutics. 2015 Jan;12(1):234-49. doi: 10.1007/s13311-014-0305-y.

9.

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

Makinson CD, Tanaka BS, Lamar T, Goldin AL, Escayg A.

Neurobiol Dis. 2014 Aug;68:16-25. doi: 10.1016/j.nbd.2014.03.014. Epub 2014 Apr 2.

10.

Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels.

Gao R, Du Y, Wang L, Nomura Y, Satar G, Gordon D, Gurevitz M, Goldin AL, Dong K.

Neuroscience. 2014 May 30;268:297-308. doi: 10.1016/j.neuroscience.2014.03.028. Epub 2014 Mar 21.

11.

Shaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anesthetics.

Lioudyno MI, Birch AM, Tanaka BS, Sokolov Y, Goldin AL, Chandy KG, Hall JE, Alkire MT.

J Neurosci. 2013 Oct 9;33(41):16310-22. doi: 10.1523/JNEUROSCI.0344-13.2013.

12.

Modulation of voltage-gated K+ channels by the sodium channel β1 subunit.

Nguyen HM, Miyazaki H, Hoshi N, Smith BJ, Nukina N, Goldin AL, Chandy KG.

Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18577-82. doi: 10.1073/pnas.1209142109. Epub 2012 Oct 22.

13.

Substitutions in the domain III voltage-sensing module enhance the sensitivity of an insect sodium channel to a scorpion beta-toxin.

Song W, Du Y, Liu Z, Luo N, Turkov M, Gordon D, Gurevitz M, Goldin AL, Dong K.

J Biol Chem. 2011 May 6;286(18):15781-8. doi: 10.1074/jbc.M110.217000. Epub 2011 Mar 15.

14.

Sodium channel SCN1A and epilepsy: mutations and mechanisms.

Escayg A, Goldin AL.

Epilepsia. 2010 Sep;51(9):1650-8. doi: 10.1111/j.1528-1167.2010.02640.x. Review.

15.

Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities.

Martin MS, Dutt K, Papale LA, Dubé CM, Dutton SB, de Haan G, Shankar A, Tufik S, Meisler MH, Baram TZ, Goldin AL, Escayg A.

J Biol Chem. 2010 Mar 26;285(13):9823-34. doi: 10.1074/jbc.M109.078568. Epub 2010 Jan 25.

16.

Sodium channel carboxyl-terminal residue regulates fast inactivation.

Nguyen HM, Goldin AL.

J Biol Chem. 2010 Mar 19;285(12):9077-89. doi: 10.1074/jbc.M109.054940. Epub 2010 Jan 20.

17.

Role of the terminal domains in sodium channel localization.

Lee A, Goldin AL.

Channels (Austin). 2009 May-Jun;3(3):171-80. Epub 2009 May 24.

18.

A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation.

Tang B, Dutt K, Papale L, Rusconi R, Shankar A, Hunter J, Tufik S, Yu FH, Catterall WA, Mantegazza M, Goldin AL, Escayg A.

Neurobiol Dis. 2009 Jul;35(1):91-102. doi: 10.1016/j.nbd.2009.04.007. Epub 2009 May 3.

19.

Role of the amino and carboxy termini in isoform-specific sodium channel variation.

Lee A, Goldin AL.

J Physiol. 2008 Aug 15;586(16):3917-26. doi: 10.1113/jphysiol.2008.156299. Epub 2008 Jun 19.

20.
22.

An epilepsy mutation in the sodium channel SCN1A that decreases channel excitability.

Barela AJ, Waddy SP, Lickfett JG, Hunter J, Anido A, Helmers SL, Goldin AL, Escayg A.

J Neurosci. 2006 Mar 8;26(10):2714-23.

23.

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

Catterall WA, Goldin AL, Waxman SG.

Pharmacol Rev. 2005 Dec;57(4):397-409. Review.

PMID:
16382098
24.

A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction.

Spampanato J, Kearney JA, de Haan G, McEwen DP, Escayg A, Aradi I, MacDonald BT, Levin SI, Soltesz I, Benna P, Montalenti E, Isom LL, Goldin AL, Meisler MH.

J Neurosci. 2004 Nov 3;24(44):10022-34.

25.

Use-dependent potentiation of the Nav1.6 sodium channel.

Zhou W, Goldin AL.

Biophys J. 2004 Dec;87(6):3862-72. Epub 2004 Oct 1.

26.

A voltage-gated calcium-selective channel encoded by a sodium channel-like gene.

Zhou W, Chung I, Liu Z, Goldin AL, Dong K.

Neuron. 2004 Apr 8;42(1):101-12.

27.

Increased neuronal firing in computer simulations of sodium channel mutations that cause generalized epilepsy with febrile seizures plus.

Spampanato J, Aradi I, Soltesz I, Goldin AL.

J Neurophysiol. 2004 May;91(5):2040-50. Epub 2003 Dec 31.

28.

International Union of Pharmacology. XXXIX. Compendium of voltage-gated ion channels: sodium channels.

Catterall WA, Goldin AL, Waxman SG; International Union of Pharmacology.

Pharmacol Rev. 2003 Dec;55(4):575-8. Review.

PMID:
14657413
29.

Mechanisms of sodium channel inactivation.

Goldin AL.

Curr Opin Neurobiol. 2003 Jun;13(3):284-90. Review.

PMID:
12850212
30.
31.

Molecular basis of isoform-specific micro-conotoxin block of cardiac, skeletal muscle, and brain Na+ channels.

Li RA, Ennis IL, Xue T, Nguyen HM, Tomaselli GF, Goldin AL, Marbán E.

J Biol Chem. 2003 Mar 7;278(10):8717-24. Epub 2002 Dec 5.

32.

Sodium channel blocking and antiarrhythmic actions of the novel arylpiperazine rsd992.

Hayes ES, Pugsley MK, Goldin AL, Walker MJ.

Pharmacol Res. 2002 Jul;46(1):19-27.

PMID:
12208117
33.

Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels.

Tan J, Liu Z, Nomura Y, Goldin AL, Dong K.

J Neurosci. 2002 Jul 1;22(13):5300-9.

34.

Evolution of voltage-gated Na(+) channels.

Goldin AL.

J Exp Biol. 2002 Mar;205(Pt 5):575-84. Review.

35.

Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin.

Tan J, Liu Z, Tsai TD, Valles SM, Goldin AL, Dong K.

Insect Biochem Mol Biol. 2002 Apr;32(4):445-54.

36.
37.
38.
39.

Resurgence of sodium channel research.

Goldin AL.

Annu Rev Physiol. 2001;63:871-94. Review.

PMID:
11181979
40.

A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities.

Kearney JA, Plummer NW, Smith MR, Kapur J, Cummins TR, Waxman SG, Goldin AL, Meisler MH.

Neuroscience. 2001;102(2):307-17.

PMID:
11166117
41.

Potentiation of rat brain sodium channel currents by PKA in Xenopus oocytes involves the I-II linker.

Smith RD, Goldin AL.

Am J Physiol Cell Physiol. 2000 Apr;278(4):C638-45.

42.

Nomenclature of voltage-gated sodium channels.

Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN, Catterall WA.

Neuron. 2000 Nov;28(2):365-8. No abstract available.

43.

U-50,488H, a kappa opioid receptor agonist, is a more potent blocker of cardiac sodium channels than lidocaine.

Pugsley MK, Yu EJ, Goldin AL.

Proc West Pharmacol Soc. 2000;43:47-50. No abstract available.

PMID:
11056955
44.

Blockade of neuronal sodium channels by the antiepileptic drugs phenytoin, carbamazepine and sodium valproate.

Pugsley MK, Yu EJ, Mclean TH, Goldin AL.

Proc West Pharmacol Soc. 1999;42:105-8. No abstract available.

PMID:
10697707
45.

Reply

Pugsley MK, Goldin AL.

Br J Pharmacol. 2000 Jan;129(2):410-1. No abstract available.

46.

A mutation that causes ataxia shifts the voltage-dependence of the Scn8a sodium channel.

Smith MR, Goldin AL.

Neuroreport. 1999 Sep 29;10(14):3027-31.

PMID:
10549817
47.

Diversity of mammalian voltage-gated sodium channels.

Goldin AL.

Ann N Y Acad Sci. 1999 Apr 30;868:38-50. Review.

PMID:
10414280
48.
49.

Time- and voltage-dependent block of sodium channels expressed in Xenopus oocytes by RSD 921, a novel class I antiarrhythmic drug.

Pugsley MK, Goldin AL.

Proc West Pharmacol Soc. 1998;41:75-6. No abstract available.

PMID:
9836249
50.

High-level expression and detection of ion channels in Xenopus oocytes.

Shih TM, Smith RD, Toro L, Goldin AL.

Methods Enzymol. 1998;293:529-56. No abstract available.

PMID:
9711627

Supplemental Content

Loading ...
Support Center