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Items: 1 to 50 of 64

1.

Sirtuins in Alzheimer's Disease: SIRT2-Related GenoPhenotypes and Implications for PharmacoEpiGenetics.

Cacabelos R, Carril JC, Cacabelos N, Kazantsev AG, Vostrov AV, Corzo L, Cacabelos P, Goldgaber D.

Int J Mol Sci. 2019 Mar 12;20(5). pii: E1249. doi: 10.3390/ijms20051249.

2.

African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles.

Roses AD, Lutz MW, Saunders AM, Goldgaber D, Saul R, Sundseth SS, Akkari PA, Roses SM, Gottschalk WK, Whitfield KE, Vostrov AA, Hauser MA, Allingham RR, Burns DK, Chiba-Falek O, Welsh-Bohmer KA.

Alzheimers Dement. 2014 Nov;10(6):592-601.e2. doi: 10.1016/j.jalz.2014.06.009. Epub 2014 Sep 26.

3.

My story: the discovery and mapping to chromosome 21 of the Alzheimer amyloid gene.

Goldgaber D.

J Alzheimers Dis. 2006;9(3 Suppl):349-60.

PMID:
17007078
4.

Selection of peptides binding to the amyloid b-protein reveals potential inhibitors of amyloid formation.

Schwarzman AL, Tsiper M, Gregori L, Goldgaber D, Frakowiak J, Mazur-Kolecka B, Taraskina A, Pchelina S, Vitek MP.

Amyloid. 2005 Dec;12(4):199-209.

PMID:
16399644
5.

Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults.

Fishel MA, Watson GS, Montine TJ, Wang Q, Green PS, Kulstad JJ, Cook DG, Peskind ER, Baker LD, Goldgaber D, Nie W, Asthana S, Plymate SR, Schwartz MW, Craft S.

Arch Neurol. 2005 Oct;62(10):1539-44.

PMID:
16216936
6.

Amyloidogenic and anti-amyloidogenic properties of recombinant transthyretin variants.

Schwarzman AL, Tsiper M, Wente H, Wang A, Vitek MP, Vasiliev V, Goldgaber D.

Amyloid. 2004 Mar;11(1):1-9.

PMID:
15185492
7.

Somatic symptoms in women 11 years after the Chornobyl accident: prevalence and risk factors.

Bromet EJ, Gluzman S, Schwartz JE, Goldgaber D.

Environ Health Perspect. 2002 Aug;110 Suppl 4:625-9.

8.

Stress and well-being in mothers of young children 11 years after the Chornobyl nuclear power plant accident.

Adams RE, Bromet EJ, Panina N, Golovakha E, Goldgaber D, Gluzman S.

Psychol Med. 2002 Jan;32(1):143-56.

PMID:
11883724
9.

Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death.

De Vrij FM, Sluijs JA, Gregori L, Fischer DF, Hermens WT, Goldgaber D, Verhaagen J, Van Leeuwen FW, Hol EM.

FASEB J. 2001 Dec;15(14):2680-8.

PMID:
11726544
10.

Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology.

Dranovsky A, Vincent I, Gregori L, Schwarzman A, Colflesh D, Enghild J, Strittmatter W, Davies P, Goldgaber D.

Neurobiol Aging. 2001 Jul-Aug;22(4):517-28.

PMID:
11445251
11.

Ukrainian application of the Children's Somatization Inventory: psychometric properties and associations with internalizing symptoms.

Litcher L, Bromet E, Carlson G, Gilbert T, Panina N, Golovakha E, Goldgaber D, Gluzman S, Garber J.

J Abnorm Child Psychol. 2001 Apr;29(2):165-75.

PMID:
11321631
12.

The role of Alzheimer's disease-related presenilin 1 in intercellular adhesion.

Singh N, Talalayeva Y, Tsiper M, Romanov V, Dranovsky A, Colflesh D, Rudamen G, Vitek MP, Shen J, Yang X, Goldgaber D, Schwarzman AL.

Exp Cell Res. 2001 Feb 1;263(1):1-13.

PMID:
11161700
13.

Children's well-being 11 years after the Chornobyl catastrophe.

Bromet EJ, Goldgaber D, Carlson G, Panina N, Golovakha E, Gluzman SF, Gilbert T, Gluzman D, Lyubsky S, Schwartz JE.

Arch Gen Psychiatry. 2000 Jun;57(6):563-71.

PMID:
10839334
14.

School and neuropsychological performance of evacuated children in Kyiv 11 years after the Chornobyl disaster.

Litcher L, Bromet EJ, Carlson G, Squires N, Goldgaber D, Panina N, Golovakha E, Gluzman S.

J Child Psychol Psychiatry. 2000 Mar;41(3):291-9.

PMID:
10784076
15.

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells.

Kazantsev A, Preisinger E, Dranovsky A, Goldgaber D, Housman D.

Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11404-9.

16.

Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix.

Schwarzman AL, Singh N, Tsiper M, Gregori L, Dranovsky A, Vitek MP, Glabe CG, St George-Hyslop PH, Goldgaber D.

Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7932-7.

17.

Binding of amyloid beta protein to the 20 S proteasome.

Gregori L, Hainfeld JF, Simon MN, Goldgaber D.

J Biol Chem. 1997 Jan 3;272(1):58-62.

18.

Interaction of transthyretin with amyloid beta-protein: binding and inhibition of amyloid formation.

Schwarzman AL, Goldgaber D.

Ciba Found Symp. 1996;199:146-60; discussion 160-4.

PMID:
8915609
19.

Amyloid beta-protein inhibits ubiquitin-dependent protein degradation in vitro.

Gregori L, Fuchs C, Figueiredo-Pereira ME, Van Nostrand WE, Goldgaber D.

J Biol Chem. 1995 Aug 25;270(34):19702-8.

20.

USF binds to the APB alpha sequence in the promoter of the amyloid beta-protein precursor gene.

Vostrov AA, Quitschke WW, Vidal F, Schwarzman AL, Goldgaber D.

Nucleic Acids Res. 1995 Jul 25;23(14):2734-41.

21.

More on hantavirus in New England and New York.

Mackow ER, Luft BJ, Bosler E, Goldgaber D.

N Engl J Med. 1995 Feb 2;332(5):337-8. No abstract available.

PMID:
7816082
22.

Ubiquitin-mediated degradative pathway degrades the extracellular but not the intracellular form of amyloid beta-protein precursor.

Gregori L, Bhasin R, Goldgaber D.

Biochem Biophys Res Commun. 1994 Sep 30;203(3):1731-8.

PMID:
7945322
23.

Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy?

Roses AD, Pericak-Vance MA, Saunders AM, Schmechel D, Goldgaber D, Strittmatter W.

Epilepsia. 1994;35 Suppl 1:S20-8. Review.

PMID:
8293721
24.

Binding of IgG to amyloid beta A4 peptide via the heavy-chain hinge region with preservation of antigen binding.

Huang D, Martin M, Hu D, Roses AD, Goldgaber D, Strittmatter WJ.

J Neuroimmunol. 1993 Nov-Dec;48(2):199-203.

PMID:
8227317
25.

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

Schmechel DE, Saunders AM, Strittmatter WJ, Crain BJ, Hulette CM, Joo SH, Pericak-Vance MA, Goldgaber D, Roses AD.

Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9649-53.

26.

Sequestration of amyloid beta-peptide.

Goldgaber D, Schwarzman AI, Bhasin R, Gregori L, Schmechel D, Saunders AM, Roses AD, Strittmatter WJ.

Ann N Y Acad Sci. 1993 Sep 24;695:139-43. Review.

PMID:
8239272
27.

Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.

Saunders AM, Schmader K, Breitner JC, Benson MD, Brown WT, Goldfarb L, Goldgaber D, Manwaring MG, Szymanski MH, McCown N, et al.

Lancet. 1993 Sep 18;342(8873):710-1.

PMID:
8103823
28.

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

Strittmatter WJ, Weisgraber KH, Huang DY, Dong LM, Salvesen GS, Pericak-Vance M, Schmechel D, Saunders AM, Goldgaber D, Roses AD.

Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):8098-102.

29.

Avid binding of beta A amyloid peptide to its own precursor.

Strittmatter WJ, Huang DY, Bhasin R, Roses AD, Goldgaber D.

Exp Neurol. 1993 Aug;122(2):327-34.

PMID:
8405269
30.

Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart.

Ramabhadran TV, Gandy SE, Ghiso J, Czernik AJ, Ferris D, Bhasin R, Goldgaber D, Frangione B, Greengard P.

J Biol Chem. 1993 Jan 25;268(3):2009-12.

32.

Alzheimer beta/A4-amyloid precursor protein: evidence for putative amyloidogenic fragment.

Gandy SE, Bhasin R, Ramabhadran TV, Koo EH, Price DL, Goldgaber D, Greengard P.

J Neurochem. 1992 Jan;58(1):383-6.

PMID:
1345769
33.

Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene.

Goldfarb LG, Brown P, McCombie WR, Goldgaber D, Swergold GD, Wills PR, Cervenakova L, Baron H, Gibbs CJ Jr, Gajdusek DC.

Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10926-30.

34.

Expression of active secreted forms of human amyloid beta-protein precursor by recombinant baculovirus-infected insect cells.

Bhasin R, Van Nostrand WE, Saitoh T, Donets MA, Barnes EA, Quitschke WW, Goldgaber D.

Proc Natl Acad Sci U S A. 1991 Nov 15;88(22):10307-11.

35.

The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.

Van Nostrand WE, Farrow JS, Wagner SL, Bhasin R, Goldgaber D, Cotman CW, Cunningham DD.

Proc Natl Acad Sci U S A. 1991 Nov 15;88(22):10302-6.

36.

Anticipating the anti-prion protein?

Goldgaber D.

Nature. 1991 May 9;351(6322):106. No abstract available.

PMID:
1674358
37.

Clinical and molecular genetic study of a large German kindred with Gerstmann-Sträussler-Scheinker syndrome.

Brown P, Goldfarb LG, Brown WT, Goldgaber D, Rubenstein R, Kascsak RJ, Guiroy DC, Piccardo P, Boellaard JW, Gajdusek DC.

Neurology. 1991 Mar;41(3):375-9.

PMID:
1672447
38.

Support of linkage of Gerstmann-Sträussler-Scheinker syndrome to the prion protein gene on chromosome 20p12-pter.

Speer MC, Goldgaber D, Goldfarb LG, Roses AD, Pericak-Vance MA.

Genomics. 1991 Feb;9(2):366-8.

PMID:
1672296
39.

Regulation and genetic control of brain amyloid. FESN Study Group.

Gajdusek DC, Beyreuther K, Brown P, Cork LC, Cunningham DD, Frangione B, Gibbs CJ Jr, Goldfarb LG, Goldgaber D, Hsiao KK.

Brain Res Brain Res Rev. 1991 Jan-Apr;16(1):83-114. Review. No abstract available.

PMID:
1677826
40.

Identical mutation in unrelated patients with Creutzfeldt-Jakob disease.

Goldfarb LG, Brown P, Goldgaber D, Garruto RM, Yanagihara R, Asher DM, Gajdusek DC.

Lancet. 1990 Jul 21;336(8708):174-5. No abstract available.

PMID:
1973487
41.

Creutzfeldt-Jakob disease and kuru patients lack a mutation consistently found in the Gerstmann-Sträussler-Scheinker syndrome.

Goldfarb LG, Brown P, Goldgaber D, Asher DM, Rubenstein R, Brown WT, Piccardo P, Kascsak RJ, Boellaard JW, Gajdusek DC.

Exp Neurol. 1990 Jun;108(3):247-50.

PMID:
2190844
42.

Expression of the amyloid beta-protein precursor gene.

Goldgaber D, Schmechel DE.

Adv Neurol. 1990;51:163-9. Review. No abstract available.

PMID:
2104685
43.

Mutations in familial Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker's syndrome.

Goldgaber D, Goldfarb LG, Brown P, Asher DM, Brown WT, Lin S, Teener JW, Feinstone SM, Rubenstein R, Kascsak RJ, et al.

Exp Neurol. 1989 Nov;106(2):204-6.

PMID:
2572450
44.

Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells.

Goldgaber D, Harris HW, Hla T, Maciag T, Donnelly RJ, Jacobsen JS, Vitek MP, Gajdusek DC.

Proc Natl Acad Sci U S A. 1989 Oct;86(19):7606-10.

45.

Cloning of a cDNA encoding the rat high molecular weight neurofilament peptide (NF-H): developmental and tissue expression in the rat, and mapping of its human homologue to chromosomes 1 and 22.

Lieberburg I, Spinner N, Snyder S, Anderson J, Goldgaber D, Smulowitz M, Carroll Z, Emanuel B, Breitner J, Rubin L.

Proc Natl Acad Sci U S A. 1989 Apr;86(7):2463-7.

46.

Distribution of precursor amyloid-beta-protein messenger RNA in human cerebral cortex: relationship to neurofibrillary tangles and neuritic plaques.

Lewis DA, Higgins GA, Young WG, Goldgaber D, Gajdusek DC, Wilson MC, Morrison JH.

Proc Natl Acad Sci U S A. 1988 Mar;85(5):1691-5.

47.

Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer disease.

Higgins GA, Lewis DA, Bahmanyar S, Goldgaber D, Gajdusek DC, Young WG, Morrison JH, Wilson MC.

Proc Natl Acad Sci U S A. 1988 Feb;85(4):1297-301.

48.

Cellular localization of messenger RNA encoding amyloid-beta-protein in normal tissue and in Alzheimer disease.

Schmechel DE, Goldgaber D, Burkhart DS, Gilbert JR, Gajdusek DC, Roses AD.

Alzheimer Dis Assoc Disord. 1988;2(2):96-111.

PMID:
3063300
49.

Hemorrhagic fever with renal syndrome in Yugoslavia: detection of hantaviral antigen and antibody in wild rodents and serological diagnosis of human disease.

Gligić A, Obradović M, Stojanović R, Hlaca D, Antonijević B, Arnautović A, Gaon J, Frusic M, Lee P, Goldgaber D, et al.

Scand J Infect Dis. 1988;20(3):261-6.

PMID:
2900550
50.

Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimer's disease.

Bahmanyar S, Higgins GA, Goldgaber D, Lewis DA, Morrison JH, Wilson MC, Shankar SK, Gajdusek DC.

Science. 1987 Jul 3;237(4810):77-80.

PMID:
3299701

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