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Items: 34

1.

Exploring the In Vivo Role of the Mitochondrial Calcium Uniporter in Brown Fat Bioenergetics.

Flicker D, Sancak Y, Mick E, Goldberger O, Mootha VK.

Cell Rep. 2019 Apr 30;27(5):1364-1375.e5. doi: 10.1016/j.celrep.2019.04.013.

2.

Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome.

Schleifer G, Marutani E, Ferrari M, Sharma R, Skinner O, Goldberger O, Grange RMH, Peneyra K, Malhotra R, Wepler M, Ichinose F, Bloch DB, Mootha VK, Zapol WM.

Am J Physiol Lung Cell Mol Physiol. 2019 Feb 1;316(2):L391-L399. doi: 10.1152/ajplung.00419.2018. Epub 2018 Dec 6.

3.

Modulation of allergic responses by mitochondrial STAT3 inhibitors.

Erlich TH, Sharkia I, Landolina N, Assayag M, Goldberger O, Berkman N, Levi-Schaffer F, Razin E.

Allergy. 2018 Nov;73(11):2160-2171. doi: 10.1111/all.13467. Epub 2018 Oct 30.

PMID:
29683527
4.

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter.

Bick AG, Wakimoto H, Kamer KJ, Sancak Y, Goldberger O, Axelsson A, DeLaughter DM, Gorham JM, Mootha VK, Seidman JG, Seidman CE.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9096-E9104. doi: 10.1073/pnas.1711303114. Epub 2017 Oct 9.

5.

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome.

Ferrari M, Jain IH, Goldberger O, Rezoagli E, Thoonen R, Cheng KH, Sosnovik DE, Scherrer-Crosbie M, Mootha VK, Zapol WM.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4241-E4250. doi: 10.1073/pnas.1621511114. Epub 2017 May 8. Erratum in: Proc Natl Acad Sci U S A. 2018 Jan 30;:. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4894-E4896.

6.

Mitochondrial dysfunction remodels one-carbon metabolism in human cells.

Bao XR, Ong SE, Goldberger O, Peng J, Sharma R, Thompson DA, Vafai SB, Cox AG, Marutani E, Ichinose F, Goessling W, Regev A, Carr SA, Clish CB, Mootha VK.

Elife. 2016 Jun 16;5. pii: e10575. doi: 10.7554/eLife.10575.

7.

Hypoxia as a therapy for mitochondrial disease.

Jain IH, Zazzeron L, Goli R, Alexa K, Schatzman-Bone S, Dhillon H, Goldberger O, Peng J, Shalem O, Sanjana NE, Zhang F, Goessling W, Zapol WM, Mootha VK.

Science. 2016 Apr 1;352(6281):54-61. doi: 10.1126/science.aad9642. Epub 2016 Feb 25.

8.

Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease.

Kattah NH, Newell EW, Jarrell JA, Chu AD, Xie J, Kattah MG, Goldberger O, Ye J, Chakravarty EF, Davis MM, Utz PJ.

Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3044-9. doi: 10.1073/pnas.1424796112. Epub 2015 Feb 23.

9.

EMRE is an essential component of the mitochondrial calcium uniporter complex.

Sancak Y, Markhard AL, Kitami T, Kovács-Bogdán E, Kamer KJ, Udeshi ND, Carr SA, Chaudhuri D, Clapham DE, Li AA, Calvo SE, Goldberger O, Mootha VK.

Science. 2013 Dec 13;342(6164):1379-82. doi: 10.1126/science.1242993. Epub 2013 Nov 14.

10.

Significance analysis of xMap cytokine bead arrays.

Won JH, Goldberger O, Shen-Orr SS, Davis MM, Olshen RA.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2848-53. doi: 10.1073/pnas.1112599109. Epub 2012 Feb 9.

11.

Split immunity: immune inhibition of rat gliomas by subcutaneous exposure to unmodified live tumor cells.

Volovitz I, Marmor Y, Azulay M, Machlenkin A, Goldberger O, Mor F, Slavin S, Ram Z, Cohen IR, Eisenbach L.

J Immunol. 2011 Nov 15;187(10):5452-62. doi: 10.4049/jimmunol.1003946. Epub 2011 Oct 12.

12.

Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation.

Tucker EJ, Hershman SG, Köhrer C, Belcher-Timme CA, Patel J, Goldberger OA, Christodoulou J, Silberstein JM, McKenzie M, Ryan MT, Compton AG, Jaffe JD, Carr SA, Calvo SE, RajBhandary UL, Thorburn DR, Mootha VK.

Cell Metab. 2011 Sep 7;14(3):428-34. doi: 10.1016/j.cmet.2011.07.010.

13.

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.

Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y, Bao XR, Strittmatter L, Goldberger O, Bogorad RL, Koteliansky V, Mootha VK.

Nature. 2011 Jun 19;476(7360):341-5. doi: 10.1038/nature10234.

14.

High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency.

Calvo SE, Tucker EJ, Compton AG, Kirby DM, Crawford G, Burtt NP, Rivas M, Guiducci C, Bruno DL, Goldberger OA, Redman MC, Wiltshire E, Wilson CJ, Altshuler D, Gabriel SB, Daly MJ, Thorburn DR, Mootha VK.

Nat Genet. 2010 Oct;42(10):851-8. doi: 10.1038/ng.659. Epub 2010 Sep 5.

15.

A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells.

Shaham O, Slate NG, Goldberger O, Xu Q, Ramanathan A, Souza AL, Clish CB, Sims KB, Mootha VK.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1571-5. doi: 10.1073/pnas.0906039107. Epub 2010 Jan 8.

16.

T-cell seeding: neonatal transfer of anti-myelin basic protein T-cell lines renders Fischer rats susceptible later in life to the active induction of experimental autoimmune encephalitis.

Volovitz I, Mor F, Machlenkin A, Goldberger O, Marmor Y, Eisenbach L, Cohen IR.

Immunology. 2009 Sep;128(1):92-102. doi: 10.1111/j.1365-2567.2009.03074.x. Erratum in: Immunology. 2009 Nov;128(3):459. Machlenkin, Athur [corrected to Machlenkin, Arthur]; Cohen, Irun [corrected to Cohen, Irun R].

17.

Towards a cytokine-cell interaction knowledgebase of the adaptive immune system.

Shen-Orr SS, Goldberger O, Garten Y, Rosenberg-Hasson Y, Lovelace PA, Hirschberg DL, Altman RB, Davis MM, Butte AJ.

Pac Symp Biocomput. 2009:439-50.

18.

Exuberated numbers of tumor-specific T cells result in tumor escape.

Goldberger O, Volovitz I, Machlenkin A, Vadai E, Tzehoval E, Eisenbach L.

Cancer Res. 2008 May 1;68(9):3450-7. doi: 10.1158/0008-5472.CAN-07-5006.

19.

Syndecan-1 expression in epithelial cells is induced by transforming growth factor beta through a PKA-dependent pathway.

Hayashida K, Johnston DR, Goldberger O, Park PW.

J Biol Chem. 2006 Aug 25;281(34):24365-74. Epub 2006 Jun 28.

20.

Preventive and therapeutic vaccination with PAP-3, a novel human prostate cancer peptide, inhibits carcinoma development in HLA transgenic mice.

Machlenkin A, Azriel-Rosenfeld R, Volovitz I, Vadai E, Lev A, Paz A, Goldberger O, Reiter Y, Tzehoval E, Benhar I, Eisenbach L.

Cancer Immunol Immunother. 2007 Feb;56(2):217-26. Epub 2006 Jun 1.

PMID:
16738849
21.

Insulin promotes shedding of syndecan ectodomains from 3T3-L1 adipocytes: a proposed mechanism for stabilization of extracellular lipoprotein lipase.

Reizes O, Goldberger O, Smith AC, Xu Z, Bernfield M, Bickel PE.

Biochemistry. 2006 May 9;45(18):5703-11.

PMID:
16669614
22.

Systematic identification of human mitochondrial disease genes through integrative genomics.

Calvo S, Jain M, Xie X, Sheth SA, Chang B, Goldberger OA, Spinazzola A, Zeviani M, Carr SA, Mootha VK.

Nat Genet. 2006 May;38(5):576-82. Epub 2006 Apr 2.

PMID:
16582907
23.

Human CTL epitopes prostatic acid phosphatase-3 and six-transmembrane epithelial antigen of prostate-3 as candidates for prostate cancer immunotherapy.

Machlenkin A, Paz A, Bar Haim E, Goldberger O, Finkel E, Tirosh B, Volovitz I, Vadai E, Lugassy G, Cytron S, Lemonnier F, Tzehoval E, Eisenbach L.

Cancer Res. 2005 Jul 15;65(14):6435-42.

24.

Combined dendritic cell cryotherapy of tumor induces systemic antimetastatic immunity.

Machlenkin A, Goldberger O, Tirosh B, Paz A, Volovitz I, Bar-Haim E, Lee SH, Vadai E, Tzehoval E, Eisenbach L.

Clin Cancer Res. 2005 Jul 1;11(13):4955-61.

26.

Expression of FasL by tumor cells does not abrogate anti-tumor CTL function.

Lee SH, Bar-Haim E, Goldberger O, Reich-Zeliger S, Vadai E, Tzehoval E, Eisenbach L.

Immunol Lett. 2004 Feb 15;91(2-3):119-26.

PMID:
15019279
27.

In vivo rejection of tumor cells dependent on CD8 cells that kill independently of perforin and FasL.

Lee SH, Bar-Haim E, Machlenkin A, Goldberger O, Volovitz I, Vadai E, Tzehoval E, Eisenbach L.

Cancer Gene Ther. 2004 Mar;11(3):237-48.

PMID:
14739939
28.

Syndecan-1 and -4 synthesized simultaneously by mouse mammary gland epithelial cells bear heparan sulfate chains that are apparently structurally indistinguishable.

Zako M, Dong J, Goldberger O, Bernfield M, Gallagher JT, Deakin JA.

J Biol Chem. 2003 Apr 11;278(15):13561-9. Epub 2003 Feb 5.

29.

Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse.

Stepp MA, Gibson HE, Gala PH, Iglesia DD, Pajoohesh-Ganji A, Pal-Ghosh S, Brown M, Aquino C, Schwartz AM, Goldberger O, Hinkes MT, Bernfield M.

J Cell Sci. 2002 Dec 1;115(Pt 23):4517-31.

30.

Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3.

Reizes O, Lincecum J, Wang Z, Goldberger O, Huang L, Kaksonen M, Ahima R, Hinkes MT, Barsh GS, Rauvala H, Bernfield M.

Cell. 2001 Jul 13;106(1):105-16.

31.

Syndecan-1 shedding is enhanced by LasA, a secreted virulence factor of Pseudomonas aeruginosa.

Park PW, Pier GB, Preston MJ, Goldberger O, Fitzgerald ML, Bernfield M.

J Biol Chem. 2000 Feb 4;275(5):3057-64.

32.
33.

Mapping of the syndecan genes in the mouse: linkage with members of the myc gene family.

Spring J, Goldberger OA, Jenkins NA, Gilbert DJ, Copeland NG, Bernfield M.

Genomics. 1994 Jun;21(3):597-601.

PMID:
7959737
34.

Organization and promoter activity of the mouse syndecan-1 gene.

Hinkes MT, Goldberger OA, Neumann PE, Kokenyesi R, Bernfield M.

J Biol Chem. 1993 May 25;268(15):11440-8.

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