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Items: 14

1.

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study.

Overman MJ, McDermott R, Leach JL, Lonardi S, Lenz HJ, Morse MA, Desai J, Hill A, Axelson M, Moss RA, Goldberg MV, Cao ZA, Ledeine JM, Maglinte GA, Kopetz S, André T.

Lancet Oncol. 2017 Sep;18(9):1182-1191. doi: 10.1016/S1470-2045(17)30422-9. Epub 2017 Jul 19. Erratum in: Lancet Oncol. 2017 Sep;18(9):e510.

2.

Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody.

Zhang D, Goldberg MV, Chiu ML.

J Biol Chem. 2016 Dec 30;291(53):27134-27146. doi: 10.1074/jbc.M116.757773. Epub 2016 Nov 17.

3.

Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer.

Wada S, Jackson CM, Yoshimura K, Yen HR, Getnet D, Harris TJ, Goldberg MV, Bruno TC, Grosso JF, Durham N, Netto GJ, Pardoll DM, Drake CG.

J Transl Med. 2013 Apr 4;11:89. doi: 10.1186/1479-5876-11-89.

4.

Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape.

Woo SR, Turnis ME, Goldberg MV, Bankoti J, Selby M, Nirschl CJ, Bettini ML, Gravano DM, Vogel P, Liu CL, Tangsombatvisit S, Grosso JF, Netto G, Smeltzer MP, Chaux A, Utz PJ, Workman CJ, Pardoll DM, Korman AJ, Drake CG, Vignali DA.

Cancer Res. 2012 Feb 15;72(4):917-27. doi: 10.1158/0008-5472.CAN-11-1620. Epub 2011 Dec 20.

5.

LAG-3 in Cancer Immunotherapy.

Goldberg MV, Drake CG.

Curr Top Microbiol Immunol. 2011;344:269-78. doi: 10.1007/82_2010_114. Review.

6.

A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells.

Getnet D, Grosso JF, Goldberg MV, Harris TJ, Yen HR, Bruno TC, Durham NM, Hipkiss EL, Pyle KJ, Wada S, Pan F, Pardoll DM, Drake CG.

Mol Immunol. 2010 Apr;47(7-8):1595-600. doi: 10.1016/j.molimm.2010.02.001. Epub 2010 Mar 11.

7.

Tc17 CD8 T cells: functional plasticity and subset diversity.

Yen HR, Harris TJ, Wada S, Grosso JF, Getnet D, Goldberg MV, Liang KL, Bruno TC, Pyle KJ, Chan SL, Anders RA, Trimble CL, Adler AJ, Lin TY, Pardoll DM, Huang CT, Drake CG.

J Immunol. 2009 Dec 1;183(11):7161-8. doi: 10.4049/jimmunol.0900368. Epub 2009 Nov 16.

8.

Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells.

Grosso JF, Goldberg MV, Getnet D, Bruno TC, Yen HR, Pyle KJ, Hipkiss E, Vignali DA, Pardoll DM, Drake CG.

J Immunol. 2009 Jun 1;182(11):6659-69. doi: 10.4049/jimmunol.0804211.

9.

Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model.

Wada S, Yoshimura K, Hipkiss EL, Harris TJ, Yen HR, Goldberg MV, Grosso JF, Getnet D, Demarzo AM, Netto GJ, Anders R, Pardoll DM, Drake CG.

Cancer Res. 2009 May 15;69(10):4309-18. doi: 10.1158/0008-5472.CAN-08-4102. Epub 2009 May 12.

10.

Tumor recognition and self-recognition induce distinct transcriptional profiles in antigen-specific CD4 T cells.

Getnet D, Maris CH, Hipkiss EL, Grosso JF, Harris TJ, Yen HR, Bruno TC, Wada S, Adler A, Georgantas RW, Jie C, Goldberg MV, Pardoll DM, Drake CG.

J Immunol. 2009 Apr 15;182(8):4675-85. doi: 10.4049/jimmunol.0803400.

11.

Radiotherapy augments the immune response to prostate cancer in a time-dependent manner.

Harris TJ, Hipkiss EL, Borzillary S, Wada S, Grosso JF, Yen HR, Getnet D, Bruno TC, Goldberg MV, Pardoll DM, DeWeese TL, Drake CG.

Prostate. 2008 Sep 1;68(12):1319-29. doi: 10.1002/pros.20794.

12.

LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems.

Grosso JF, Kelleher CC, Harris TJ, Maris CH, Hipkiss EL, De Marzo A, Anders R, Netto G, Getnet D, Bruno TC, Goldberg MV, Pardoll DM, Drake CG.

J Clin Invest. 2007 Nov;117(11):3383-92.

13.

Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity.

Harris TJ, Grosso JF, Yen HR, Xin H, Kortylewski M, Albesiano E, Hipkiss EL, Getnet D, Goldberg MV, Maris CH, Housseau F, Yu H, Pardoll DM, Drake CG.

J Immunol. 2007 Oct 1;179(7):4313-7.

14.

Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells.

Goldberg MV, Maris CH, Hipkiss EL, Flies AS, Zhen L, Tuder RM, Grosso JF, Harris TJ, Getnet D, Whartenby KA, Brockstedt DG, Dubensky TW Jr, Chen L, Pardoll DM, Drake CG.

Blood. 2007 Jul 1;110(1):186-92. Epub 2007 Mar 28.

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