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Items: 17


Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response to Mycobacterium tuberculosis in vivo.

Rothchild AC, Olson GS, Nemeth J, Amon LM, Mai D, Gold ES, Diercks AH, Aderem A.

Sci Immunol. 2019 Jul 26;4(37). pii: eaaw6693. doi: 10.1126/sciimmunol.aaw6693.


An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux.

Gillespie MA, Gold ES, Ramsey SA, Podolsky I, Aderem A, Ranish JA.

EMBO J. 2015 May 5;34(9):1244-58. doi: 10.15252/embj.201489819. Epub 2015 Mar 9.


Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway.

Ramsey SA, Vengrenyuk Y, Menon P, Podolsky I, Feig JE, Aderem A, Fisher EA, Gold ES.

PLoS Genet. 2014 Dec 4;10(12):e1004828. doi: 10.1371/journal.pgen.1004828. eCollection 2014 Dec.


25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.

Gold ES, Diercks AH, Podolsky I, Podyminogin RL, Askovich PS, Treuting PM, Aderem A.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10666-71. doi: 10.1073/pnas.1404271111. Epub 2014 Jul 3.


ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation.

Gold ES, Ramsey SA, Sartain MJ, Selinummi J, Podolsky I, Rodriguez DJ, Moritz RL, Aderem A.

J Exp Med. 2012 Apr 9;209(4):807-17. doi: 10.1084/jem.20111202. Epub 2012 Apr 2.


Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses.

Zak DE, Schmitz F, Gold ES, Diercks AH, Peschon JJ, Valvo JS, Niemistö A, Podolsky I, Fallen SG, Suen R, Stolyar T, Johnson CD, Kennedy KA, Hamilton MK, Siggs OM, Beutler B, Aderem A.

Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11536-41. doi: 10.1073/pnas.1107577108. Epub 2011 Jun 27.


Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites.

Ramsey SA, Knijnenburg TA, Kennedy KA, Zak DE, Gilchrist M, Gold ES, Johnson CD, Lampano AE, Litvak V, Navarro G, Stolyar T, Aderem A, Shmulevich I.

Bioinformatics. 2010 Sep 1;26(17):2071-5. doi: 10.1093/bioinformatics/btq405. Epub 2010 Jul 27.


A systems biology approach to understanding atherosclerosis.

Ramsey SA, Gold ES, Aderem A.

EMBO Mol Med. 2010 Mar;2(3):79-89. doi: 10.1002/emmm.201000063. Review.


Hematopoietic cell types: prototype for a revised cell ontology.

Diehl AD, Augustine AD, Blake JA, Cowell LG, Gold ES, Gondré-Lewis TA, Masci AM, Meehan TF, Morel PA, Nijnik A, Peters B, Pulendran B, Scheuermann RH, Yao QA, Zand MS, Mungall CJ.

J Biomed Inform. 2011 Feb;44(1):75-9. doi: 10.1016/j.jbi.2010.01.006. Epub 2010 Feb 1.


Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics.

Ramsey SA, Klemm SL, Zak DE, Kennedy KA, Thorsson V, Li B, Gilchrist M, Gold ES, Johnson CD, Litvak V, Navarro G, Roach JC, Rosenberger CM, Rust AG, Yudkovsky N, Aderem A, Shmulevich I.

PLoS Comput Biol. 2008 Mar 21;4(3):e1000021. doi: 10.1371/journal.pcbi.1000021. Erratum in: PLoS Comput Biol. 2008 Mar;4(3). doi: 10.1371/annotation/1c55be5f-ecd7-49be-91c1-91881be60297. PLoS Comput Biol. 2008 Mar;4(3). doi: 10.1371/annotation/e14ad837-e5ff-4bd5-a5f2-f32e784d75a2.


Amphiphysin IIm is required for survival of Chlamydia pneumoniae in macrophages.

Gold ES, Simmons RM, Petersen TW, Campbell LA, Kuo CC, Aderem A.

J Exp Med. 2004 Sep 6;200(5):581-6. Epub 2004 Aug 30.


Amphiphysin IIm, a novel amphiphysin II isoform, is required for macrophage phagocytosis.

Gold ES, Morrissette NS, Underhill DM, Guo J, Bassetti M, Aderem A.

Immunity. 2000 Mar;12(3):285-92.


Eagle's syndrome in an 11-year-old patient.

Quereshy FA, Gold ES, Arnold J, Powers MP.

J Oral Maxillofac Surg. 2001 Jan;59(1):94-7. No abstract available.


Hemolytic anemia in a glucose-6-phosphate dehydrogenase-deficient patient triggered by a maxillofacial infection.

Quereshy FA, Gold ES, Powers MP.

J Oral Maxillofac Surg. 2000 Jul;58(7):805-7. Review. No abstract available.


Dynamin 2 is required for phagocytosis in macrophages.

Gold ES, Underhill DM, Morrissette NS, Guo J, McNiven MA, Aderem A.

J Exp Med. 1999 Dec 20;190(12):1849-56.


Isolation and characterization of monoclonal antibodies directed against novel components of macrophage phagosomes.

Morrissette NS, Gold ES, Guo J, Hamerman JA, Ozinsky A, Bedian V, Aderem AA.

J Cell Sci. 1999 Dec;112 ( Pt 24):4705-13.

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