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Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.

Lopez Quezada L, Silve S, Kelinske M, Liba A, Diaz Gonzalez C, Kotev M, Goullieux L, Sans S, Roubert C, Lagrange S, Bacqué E, Couturier C, Pellet A, Blanc I, Ferron M, Debu F, Li K, Aubé J, Roberts J, Little D, Ling Y, Zhang J, Gold B, Nathan C.

MBio. 2019 Jul 9;10(4). pii: e01405-19. doi: 10.1128/mBio.01405-19.

Free Article

Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis.

Lopez Quezada L, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K, Somersan Karakaya S, Javidnia PE, Porras de Francisco E, Amieva MM, Dı Az SP, Mendoza Losana A, Zimmerman M, Liang HH, Zhang J, Dartois V, Sans S, Lagrange S, Goullieux L, Roubert C, Nathan C, Aubé J.

ACS Infect Dis. 2019 Jun 11. doi: 10.1021/acsinfecdis.9b00112. [Epub ahead of print]


Non-fasting High-Density Lipoprotein Is Associated With White Matter Microstructure in Healthy Older Adults.

Johnson NF, Gold BT, Ross D, Bailey AL, Clasey JL, Gupta V, Leung SW, Powell DK.

Front Aging Neurosci. 2019 May 7;11:100. doi: 10.3389/fnagi.2019.00100. eCollection 2019.


An nπ* Interaction in the Bound Substrate of Aspartic Proteases Replicates the Oxyanion Hole.

Windsor IW, Gold B, Raines RT.

ACS Catal. 2019 Feb 1;9(2):1464-1471. doi: 10.1021/acscatal.8b04142. Epub 2018 Nov 29.


Fractionating auditory priors: A neural dissociation between active and passive experience of musical sounds.

Kliuchko M, Brattico E, Gold BP, Tervaniemi M, Bogert B, Toiviainen P, Vuust P.

PLoS One. 2019 May 3;14(5):e0216499. doi: 10.1371/journal.pone.0216499. eCollection 2019.


Size and Prevalence of Pediatric Aerodigestive Programs in 2017.

Gumer L, Rosen R, Gold BD, Chiou EH, Greifer M, Cohen S, Friedlander JA.

J Pediatr Gastroenterol Nutr. 2019 May;68(5):e72-e76. doi: 10.1097/MPG.0000000000002268.


Distinct patterns of default mode and executive control network circuitry contribute to present and future executive function in older adults.

Brown CA, Schmitt FA, Smith CD, Gold BT.

Neuroimage. 2019 Jul 15;195:320-332. doi: 10.1016/j.neuroimage.2019.03.073. Epub 2019 Apr 4.


Direct Assessment of Tube Dilation in Entangled Polymers.

Gold BJ, Pyckhout-Hintzen W, Wischnewski A, Radulescu A, Monkenbusch M, Allgaier J, Hoffmann I, Parisi D, Vlassopoulos D, Richter D.

Phys Rev Lett. 2019 Mar 1;122(8):088001. doi: 10.1103/PhysRevLett.122.088001.


Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.

Zimmerman M, McDonald SL, Ho-Liang HP, Porubsky P, Nguyen Q, Pharr CW, Perkowski AJ, Smith R, Schoenen FJ, Gold BS, Zhang D, Nathan CF, Dartois V, Aubé J.

J Antibiot (Tokyo). 2019 Jun;72(6):469-475. doi: 10.1038/s41429-019-0167-y. Epub 2019 Mar 22.


Origin of mutations in genes associated with human glioblastoma multiform cancer: random polymerase errors versus deamination.

Zhang M, Yang D, Gold B.

Heliyon. 2019 Mar 7;5(3):e01265. doi: 10.1016/j.heliyon.2019.e01265. eCollection 2019 Mar.


Surprise-related activation in the nucleus accumbens interacts with music-induced pleasantness.

Shany O, Singer N, Gold BP, Jacoby N, Tarrasch R, Hendler T, Granot R.

Soc Cogn Affect Neurosci. 2019 May 17;14(4):459-470. doi: 10.1093/scan/nsz019.


Mechanisms underlying resilience in ageing.

Stern Y, Chételat G, Habeck C, Arenaza-Urquijo EM, Vemuri P, Estanga A, Bartrés-Faz D, Cantillon M, Clouston SAP, Elman JA, Gold BT, Jones R, Kempermann G, Lim YY, van Loenhoud A, Martínez-Lage P, Morbelli S, Okonkwo O, Ossenkoppele R, Pettigrew C, Rosen AC, Scarmeas N, Soldan A, Udeh-Momoh C, Valenzuela M, Vuoksimaa E.

Nat Rev Neurosci. 2019 Apr;20(4):246. doi: 10.1038/s41583-019-0138-0. No abstract available.


Musical reward prediction errors engage the nucleus accumbens and motivate learning.

Gold BP, Mas-Herrero E, Zeighami Y, Benovoy M, Dagher A, Zatorre RJ.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3310-3315. doi: 10.1073/pnas.1809855116. Epub 2019 Feb 6.


Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.

Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S, Fraisse L, Sans S, Couturier C, Bacqué E, Rhee K, Scarry SM, Aubé J, Yang G, Ouerfelli O, Schnappinger D, Ioerger TR, Engelhart CA, McConnell JA, McAulay K, Fay A, Roubert C, Sacchettini J, Nathan C.

Science. 2019 Feb 1;363(6426). pii: eaau8959. doi: 10.1126/science.aau8959. Erratum in: Science. 2019 Jun 21;364(6446):.


Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.

Early J, Ollinger J, Darby C, Alling T, Mullen S, Casey A, Gold B, Ochoada J, Wiernicki T, Masquelin T, Nathan C, Hipskind PA, Parish T.

ACS Infect Dis. 2019 Feb 8;5(2):272-280. doi: 10.1021/acsinfecdis.8b00256. Epub 2018 Dec 17.


Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β1-42 and Hypertension.

Al-Janabi OM, Brown CA, Bahrani AA, Abner EL, Barber JM, Gold BT, Goldstein LB, Murphy RR, Nelson PT, Johnson NF, Shaw LM, Smith CD, Trojanowski JQ, Wilcock DM, Jicha GA.

J Alzheimers Dis. 2018;66(3):1095-1104. doi: 10.3233/JAD-180663.


Dual Delayed-Release Dexlansoprazole for Healing and Maintenance of Healed Erosive Esophagitis: A Safety Study in Adolescents.

Gremse D, Gold BD, Pilmer B, Hunt B, Korczowski B, Perez MC.

Dig Dis Sci. 2019 Feb;64(2):493-502. doi: 10.1007/s10620-018-5325-8. Epub 2018 Nov 2.


The power of agricultural data.

Woodard JD, Sherrick BJ, Atwood DM, Blair R, Fogel G, Goeser N, Gold B, Lewis J, Mattson C, Moseley J, O'Mara C, Piotti J, Salas B, Scarlett L, Duncanson KW, Yoder F.

Science. 2018 Oct 26;362(6413):410-411. doi: 10.1126/science.aav5002. No abstract available.


Sub-picomolar Inhibition of HIV-1 Protease with a Boronic Acid.

Windsor IW, Palte MJ, Lukesh JC 3rd, Gold B, Forest KT, Raines RT.

J Am Chem Soc. 2018 Oct 31;140(43):14015-14018. doi: 10.1021/jacs.8b07366. Epub 2018 Oct 22.


Thermodynamic Stability of DNA Duplexes Comprising the Simplest T → dU Substitutions.

Carr CE, Khutsishvili I, Gold B, Marky LA.

Biochemistry. 2018 Oct 2;57(39):5666-5671. doi: 10.1021/acs.biochem.8b00676. Epub 2018 Sep 17.


A Combination of Essential Fatty Acids, Panax Ginseng Extract, and Green Tea Catechins Modifies Brain fMRI Signals in Healthy Older Adults.

Carmichael OT, Pillai S, Shankapal P, McLellan A, Kay DG, Gold BT, Keller JN.

J Nutr Health Aging. 2018;22(7):837-846. doi: 10.1007/s12603-018-1028-2.


A Mild Traumatic Brain Injury in Mice Produces Lasting Deficits in Brain Metabolism.

Lyons DN, Vekaria H, Macheda T, Bakshi V, Powell DK, Gold BT, Lin AL, Sullivan PG, Bachstetter AD.

J Neurotrauma. 2018 Oct 15;35(20):2435-2447. doi: 10.1089/neu.2018.5663. Epub 2018 Jul 2.


Clinical Characteristics of Disaccharidase Deficiencies Among Children Undergoing Upper Endoscopy.

Cohen SA, Oloyede H, Gold BD, Mohammed A, Elser HE.

J Pediatr Gastroenterol Nutr. 2018 Jun;66 Suppl 3:S56-S60. doi: 10.1097/MPG.0000000000001961.


Age and Alzheimer's pathology disrupt default mode network functioning via alterations in white matter microstructure but not hyperintensities.

Brown CA, Jiang Y, Smith CD, Gold BT.

Cortex. 2018 Jul;104:58-74. doi: 10.1016/j.cortex.2018.04.006. Epub 2018 Apr 19.


The Adenomatous Polyposis Coli (APC) mutation spectra in different anatomical regions of the large intestine in colorectal cancer.

Zhang M, Yang D, Gold B.

Mutat Res. 2018 Jul;810:1-5. doi: 10.1016/j.mrfmmm.2018.04.003. Epub 2018 May 1.


Prevalence of Helicobacter pylori among Alaskans: Factors associated with infection and comparison of urea breath test and anti-Helicobacter pylori IgG antibodies.

Miernyk KM, Bulkow LR, Gold BD, Bruce MG, Hurlburt DH, Griffin PM, Swerdlow DL, Cook K, Hennessy TW, Parkinson AJ.

Helicobacter. 2018 Jun;23(3):e12482. doi: 10.1111/hel.12482. Epub 2018 Mar 14.


Opinion: How to bring science and technology expertise to state governments.

Alberts B, Gold BD, Martin LL, Maxon ME.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):1952-1955. doi: 10.1073/pnas.1800543115. No abstract available.


Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.

Negri A, Javidnia P, Mu R, Zhang X, Vendome J, Gold B, Roberts J, Barman D, Ioerger T, Sacchettini JC, Jiang X, Burns-Huang K, Warrier T, Ling Y, Warren JD, Oren DA, Beuming T, Wang H, Wu J, Li H, Rhee KY, Nathan CF, Liu G, Somersan-Karakaya S.

ACS Infect Dis. 2018 May 11;4(5):771-787. doi: 10.1021/acsinfecdis.7b00111. Epub 2018 Feb 21.


Targeting the Proteostasis Network for Mycobacterial Drug Discovery.

Lupoli TJ, Vaubourgeix J, Burns-Huang K, Gold B.

ACS Infect Dis. 2018 Apr 13;4(4):478-498. doi: 10.1021/acsinfecdis.7b00231. Epub 2018 Mar 2. Review.


Structure and Functions of Pediatric Aerodigestive Programs: A Consensus Statement.

Boesch RP, Balakrishnan K, Acra S, Benscoter DT, Cofer SA, Collaco JM, Dahl JP, Daines CL, DeAlarcon A, DeBoer EM, Deterding RR, Friedlander JA, Gold BD, Grothe RM, Hart CK, Kazachkov M, Lefton-Greif MA, Miller CK, Moore PE, Pentiuk S, Peterson-Carmichael S, Piccione J, Prager JD, Putnam PE, Rosen R, Rutter MJ, Ryan MJ, Skinner ML, Torres-Silva C, Wootten CT, Zur KB, Cotton RT, Wood RE.

Pediatrics. 2018 Mar;141(3). pii: e20171701. doi: 10.1542/peds.2017-1701. Epub 2018 Feb 7.


Image-guided placement of percutaneous de novo low-profile gastrojejunostomy tubes in the pediatric population: a study of feasibility and efficacy.

Gill AE, Gallagher N, McElhanon BO, Painter AR, Gold BD, Hawkins CM.

Pediatr Radiol. 2018 Jun;48(6):882-888. doi: 10.1007/s00247-018-4082-3. Epub 2018 Feb 8.


[Femoral hernia in geriatric patient].

Ischer D, Renoult C, Gold B, Mégevand JM.

Rev Med Suisse. 2018 Jan 31;14(592):279-282. French.


Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities.

Al-Janabi OM, Panuganti P, Abner EL, Bahrani AA, Murphy R, Bardach SH, Caban-Holt A, Nelson PT, Gold BT, Smith CD, Wilcock DM, Jicha GA.

J Neuroimaging. 2018 May;28(3):301-306. doi: 10.1111/jon.12494. Epub 2018 Jan 5.


Value-Based Care and Strategic Priorities.

Gross WL, Cooper L, Boggs S, Gold B.

Anesthesiol Clin. 2017 Dec;35(4):725-731. doi: 10.1016/j.anclin.2017.08.008. Review.


Dexlansoprazole for Heartburn Relief in Adolescents with Symptomatic, Nonerosive Gastro-esophageal Reflux Disease.

Gold BD, Pilmer B, Kierkuś J, Hunt B, Perez MC, Gremse D.

Dig Dis Sci. 2017 Nov;62(11):3059-3068. doi: 10.1007/s10620-017-4743-3. Epub 2017 Sep 15.


Endothelial Function Is Associated with White Matter Microstructure and Executive Function in Older Adults.

Johnson NF, Gold BT, Brown CA, Anggelis EF, Bailey AL, Clasey JL, Powell DK.

Front Aging Neurosci. 2017 Aug 2;9:255. doi: 10.3389/fnagi.2017.00255. eCollection 2017.


Clinically silent Alzheimer's and vascular pathologies influence brain networks supporting executive function in healthy older adults.

Gold BT, Brown CA, Hakun JG, Shaw LM, Trojanowski JQ, Smith CD.

Neurobiol Aging. 2017 Oct;58:102-111. doi: 10.1016/j.neurobiolaging.2017.06.012. Epub 2017 Jun 24.


Origin of Somatic Mutations in β-Catenin versus Adenomatous Polyposis Coli in Colon Cancer: Random Mutagenesis in Animal Models versus Nonrandom Mutagenesis in Humans.

Yang D, Zhang M, Gold B.

Chem Res Toxicol. 2017 Jul 17;30(7):1369-1375. doi: 10.1021/acs.chemrestox.7b00092. Epub 2017 Jun 15. Review.


Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.

Saito K, Warrier T, Somersan-Karakaya S, Kaminski L, Mi J, Jiang X, Park S, Shigyo K, Gold B, Roberts J, Weber E, Jacobs WR Jr, Nathan CF.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4832-E4840. doi: 10.1073/pnas.1705385114. Epub 2017 May 30.


Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016).

Jones NL, Koletzko S, Goodman K, Bontems P, Cadranel S, Casswall T, Czinn S, Gold BD, Guarner J, Elitsur Y, Homan M, Kalach N, Kori M, Madrazo A, Megraud F, Papadopoulou A, Rowland M; ESPGHAN, NASPGHAN.

J Pediatr Gastroenterol Nutr. 2017 Jun;64(6):991-1003. doi: 10.1097/MPG.0000000000001594.


Fine-Tuning Strain and Electronic Activation of Strain-Promoted 1,3-Dipolar Cycloadditions with Endocyclic Sulfamates in SNO-OCTs.

Burke EG, Gold B, Hoang TT, Raines RT, Schomaker JM.

J Am Chem Soc. 2017 Jun 14;139(23):8029-8037. doi: 10.1021/jacs.7b03943. Epub 2017 May 31.


Next Generation Sequencing Reveals High Prevalence of BRCA1 and BRCA2 Variants of Unknown Significance in Early-Onset Breast Cancer in African American Women.

Ricks-Santi L, McDonald JT, Gold B, Dean M, Thompson N, Abbas M, Wilson B, Kanaan Y, Naab TJ, Dunston G.

Ethn Dis. 2017 Apr 20;27(2):169-178. doi: 10.18865/ed.27.2.169. eCollection 2017 Spring.


Integrating Quality Improvement and Continuing Professional Development at an Academic Medical Center: A Partnership Between Practice Plan, Hospital, and Medical School.

Gold B, England D, Riley W, Jacobs-Halsey G, Webb C, Daniels B.

J Contin Educ Health Prof. 2016 Fall;36(4):307-315. doi: 10.1097/CEH.0000000000000118.


Electronic and Steric Optimization of Fluorogenic Probes for Biomolecular Imaging.

Chyan W, Kilgore HR, Gold B, Raines RT.

J Org Chem. 2017 Apr 21;82(8):4297-4304. doi: 10.1021/acs.joc.7b00285. Epub 2017 Apr 11.


Targeting Phenotypically Tolerant Mycobacterium tuberculosis.

Gold B, Nathan C.

Microbiol Spectr. 2017 Jan;5(1). doi: 10.1128/microbiolspec.TBTB2-0031-2016. Review.


Infliximab Is Not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease.

Hyams JS, Dubinsky MC, Baldassano RN, Colletti RB, Cucchiara S, Escher J, Faubion W, Fell J, Gold BD, Griffiths A, Koletzko S, Kugathasan S, Markowitz J, Ruemmele FM, Veereman G, Winter H, Masel N, Shin CR, Tang KL, Thayu M.

Gastroenterology. 2017 Jun;152(8):1901-1914.e3. doi: 10.1053/j.gastro.2017.02.004. Epub 2017 Feb 11.


Somatic mutations in cancer: Stochastic versus predictable.

Gold B.

Mutat Res. 2017 Feb;814:37-46. doi: 10.1016/j.mrgentox.2016.12.006. Epub 2017 Jan 7. Review.


Visualization of the Charcoal Agar Resazurin Assay for Semi-quantitative, Medium-throughput Enumeration of Mycobacteria.

Gold B, Roberts J, Ling Y, Lopez Quezada L, Glasheen J, Ballinger E, Somersan-Karakaya S, Warrier T, Nathan C.

J Vis Exp. 2016 Dec 14;(118). doi: 10.3791/54690.


Clinical and Fecal Microbial Changes With Diet Therapy in Active Inflammatory Bowel Disease.

Suskind DL, Cohen SA, Brittnacher MJ, Wahbeh G, Lee D, Shaffer ML, Braly K, Hayden HS, Klein J, Gold B, Giefer M, Stallworth A, Miller SI.

J Clin Gastroenterol. 2018 Feb;52(2):155-163. doi: 10.1097/MCG.0000000000000772.


Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease.

Brown CA, Johnson NF, Anderson-Mooney AJ, Jicha GA, Shaw LM, Trojanowski JQ, Van Eldik LJ, Schmitt FA, Smith CD, Gold BT.

Neuroimage Clin. 2016 Nov 25;13:106-115. eCollection 2017.

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