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Items: 42


Population Pharmacokinetic Estimates Suggest Elevated Clearance and Distribution Volume of Desethylamodiaquine in Pediatric Patients with Sickle Cell Disease Treated with Artesunate-Amodiaquine.

Adjei GO, Amponsah SK, Goka BQ, Enweronu-Laryea C, Renner L, Sulley AM, Alifrangis M, Kurtzhals JAL.

Curr Ther Res Clin Exp. 2019 Jan 12;90:9-15. doi: 10.1016/j.curtheres.2019.01.005. eCollection 2019.


Pneumonia in Ghana-a need to raise the profile.

Abbey M, Afagbedzi SK, Afriyie-Mensah J, Antwi-Agyei D, Atengble K, Badoe E, Batchelor J, Donkor ES, Esena R, Goka BQ, Head MG, Labi AK, Nartey E, Sagoe-Moses I, Tette EMA.

Int Health. 2018 Jan 1;10(1):4-7. doi: 10.1093/inthealth/ihx062.


Paediatric emergencies in sub-Saharan Africa.

Molyneux EM, Goka BQ.

Afr J Emerg Med. 2017;7(Suppl):S1-S2. doi: 10.1016/j.afjem.2017.11.005. Epub 2017 Dec 7. No abstract available.


A STAT6 Intronic Single-Nucleotide Polymorphism is Associated with Clinical Malaria in Ghanaian Children.

Amoako-Sakyi D, Adukpo S, Kusi KA, Dodoo D, Ofori MF, Adjei GO, Edoh DE, Asmah RH, Brown C, Adu B, Obiri-Yeboah D, Futagbi G, Abubakari SB, Troye-Blomberg M, Akanmori BD, Goka BQ, Arko-Mensah J, Gyan BA.

Genet Epigenet. 2016 May 29;8:7-14. doi: 10.4137/GEG.S38307. eCollection 2016.


Polymorphisms in the Haem Oxygenase-1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children.

Hansson HH, Maretty L, Balle C, Goka BQ, Luzon E, Nkrumah FN, Schousboe ML, Rodrigues OP, Bygbjerg IC, Kurtzhals JA, Alifrangis M, Hempel C.

Malar J. 2015 Apr 11;14:153. doi: 10.1186/s12936-015-0668-5.


A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria.

Adjei GO, Goka BQ, Enweronu-Laryea CC, Rodrigues OP, Renner L, Sulley AM, Alifrangis M, Khalil I, Kurtzhals JA.

Malar J. 2014 Sep 19;13:369. doi: 10.1186/1475-2875-13-369.


High plasma levels of soluble intercellular adhesion molecule (ICAM)-1 are associated with cerebral malaria.

Adukpo S, Kusi KA, Ofori MF, Tetteh JK, Amoako-Sakyi D, Goka BQ, Adjei GO, Edoh DA, Akanmori BD, Gyan BA, Dodoo D.

PLoS One. 2013 Dec 27;8(12):e84181. doi: 10.1371/journal.pone.0084181. eCollection 2013.


Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana.

Hansson HH, Kurtzhals JA, Goka BQ, Rodriques OP, Nkrumah FN, Theander TG, Bygbjerg IC, Alifrangis M.

Malar J. 2013 Nov 7;12:400. doi: 10.1186/1475-2875-12-400.


Reversible audiometric threshold changes in children with uncomplicated malaria.

Adjei GO, Goka BQ, Kitcher E, Rodrigues OP, Badoe E, Kurtzhals JA.

J Trop Med. 2013;2013:360540. doi: 10.1155/2013/360540. Epub 2013 Mar 7.


Electrocardiographic study in Ghanaian children with uncomplicated malaria, treated with artesunate-amodiaquine or artemether-lumefantrine.

Adjei GO, Oduro-Boatey C, Rodrigues OP, Hoegberg LC, Alifrangis M, Kurtzhals JA, Goka BQ.

Malar J. 2012 Dec 17;11:420. doi: 10.1186/1475-2875-11-420.


Amodiaquine-associated adverse effects after inadvertent overdose and after a standard therapeutic dose.

Adjei GO, Goka BQ, Rodrigues OP, Hoegberg LC, Alifrangis M, Kurtzhals J.

Ghana Med J. 2009 Sep;43(3):135-8.


Parents' perceptions, attitudes and acceptability of treatment of childhood malaria with artemisinin combination therapies in ghana.

Adjei GO, Darkwah AK, Goka BQ, Bart-Plange C, Alifrangis ML, Kurtzhals JA, Rodrigues OP.

Ghana Med J. 2009 Sep;43(3):99-106.


Artemether-lumefantrine: an oral antimalarial for uncomplicated malaria in children.

Adjei GO, Goka BQ, Binka F, Kurtzhals JA.

Expert Rev Anti Infect Ther. 2009 Aug;7(6):669-81. doi: 10.1586/eri.09.53. Review.


Cerebral malaria is associated with low levels of circulating endothelial progenitor cells in African children.

Gyan B, Goka BQ, Adjei GO, Tetteh JK, Kusi KA, Aikins A, Dodoo D, Lesser ML, Sison CP, Das S, Howard ME, Milbank E, Fischer K, Rafii S, Jin D, Golightly LM.

Am J Trop Med Hyg. 2009 Apr;80(4):541-6.


Effect of concomitant artesunate administration and cytochrome P4502C8 polymorphisms on the pharmacokinetics of amodiaquine in Ghanaian children with uncomplicated malaria.

Adjei GO, Kristensen K, Goka BQ, Hoegberg LC, Alifrangis M, Rodrigues OP, Kurtzhals JA.

Antimicrob Agents Chemother. 2008 Dec;52(12):4400-6. doi: 10.1128/AAC.00673-07. Epub 2008 Sep 8.


Levels of soluble CD163 and severity of malaria in children in Ghana.

Kusi KA, Gyan BA, Goka BQ, Dodoo D, Obeng-Adjei G, Troye-Blomberg M, Akanmori BD, Adjimani JP.

Clin Vaccine Immunol. 2008 Sep;15(9):1456-60. doi: 10.1128/CVI.00506-07. Epub 2008 Jul 16.


Amodiaquine-artesunate vs artemether-lumefantrine for uncomplicated malaria in Ghanaian children: a randomized efficacy and safety trial with one year follow-up.

Adjei GO, Kurtzhals JA, Rodrigues OP, Alifrangis M, Hoegberg LC, Kitcher ED, Badoe EV, Lamptey R, Goka BQ.

Malar J. 2008 Jul 11;7:127. doi: 10.1186/1475-2875-7-127.


Complement activation in Ghanaian children with severe Plasmodium falciparum malaria.

Helegbe GK, Goka BQ, Kurtzhals JA, Addae MM, Ollaga E, Tetteh JK, Dodoo D, Ofori MF, Obeng-Adjei G, Hirayama K, Awandare GA, Akanmori BD.

Malar J. 2007 Dec 17;6:165.


Neurotoxicity of artemisinin derivatives.

Adjei GO, Goka BQ, Kurtzhals JA.

Clin Infect Dis. 2006 Dec 15;43(12):1618. No abstract available.


Are currently deployed artemisinins neurotoxic?

Adjei GO, Goka BQ, Kurtzhals JA, Gordi T.

Toxicol Lett. 2006 Dec 1;167(2):162-4; author reply 165-6. Epub 2006 Sep 12. No abstract available.


Factors contributing to the development of anaemia in Plasmodium falciparum malaria: what about drug-resistant parasites?

Quashie NB, Akanmori BD, Ofori-Adjei D, Goka BQ, Kurtzhals JA.

J Trop Pediatr. 2006 Aug;52(4):254-9. Epub 2005 Dec 2.


Circulating epstein-barr virus in children living in malaria-endemic areas.

Rasti N, Falk KI, Donati D, Gyan BA, Goka BQ, Troye-Blomberg M, Akanmori BD, Kurtzhals JA, Dodoo D, Consolini R, Linde A, Wahlgren M, Bejarano MT.

Scand J Immunol. 2005 May;61(5):461-5.


Pretreatment blood concentrations of chloroquine in patients with malaria infection: relation to response to treatment.

Quashie NB, Akanmori BD, Goka BQ, Ofori-Adjei D, Kurtzhals JA.

J Trop Pediatr. 2005 Jun;51(3):149-53. Epub 2005 Apr 14.


Plasma concentrations of soluble urokinase-type plasminogen activator receptor are increased in patients with malaria and are associated with a poor clinical or a fatal outcome.

Ostrowski SR, Ullum H, Goka BQ, Høyer-Hansen G, Obeng-Adjei G, Pedersen BK, Akanmori BD, Kurtzhals JA.

J Infect Dis. 2005 Apr 15;191(8):1331-41. Epub 2005 Mar 14.


Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens.

Nielsen MA, Vestergaard LS, Lusingu J, Kurtzhals JA, Giha HA, Grevstad B, Goka BQ, Lemnge MM, Jensen JB, Akanmori BD, Theander TG, Staalsoe T, Hviid L.

Infect Immun. 2004 Jun;72(6):3531-5.


Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes.

Garred P, Nielsen MA, Kurtzhals JA, Malhotra R, Madsen HO, Goka BQ, Akanmori BD, Sim RB, Hviid L.

Infect Immun. 2003 Sep;71(9):5245-53. Erratum in: Infect Immun. 2003 Nov;71(11):6687.


Severe malaria in west African children.

Kurtzhals JA, Helleberg M, Goka BQ, Akanmori BD.

Lancet. 2003 Apr 19;361(9366):1393. No abstract available.


Acute P. falciparum malaria induces a loss of CD28- T IFN-gamma producing cells.

Kemp K, Akanmori BD, Kurtzhals JA, Adabayeri V, Goka BQ, Hviid L.

Parasite Immunol. 2002 Nov-Dec;24(11-12):545-8.


Elevated levels of nitric oxide and low levels of haptoglobin are associated with severe malarial anaemia in African children.

Gyan B, Kurtzhals JA, Akanmori BD, Ofori M, Goka BQ, Hviid L, Behr C.

Acta Trop. 2002 Aug;83(2):133-40.


Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria.

Kemp K, Kurtzhals JA, Akanmori BD, Adabayeri V, Goka BQ, Behr C, Hviid L.

Clin Diagn Lab Immunol. 2002 May;9(3):720-2.


Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity.

Nielsen MA, Staalsoe T, Kurtzhals JA, Goka BQ, Dodoo D, Alifrangis M, Theander TG, Akanmori BD, Hviid L.

J Immunol. 2002 Apr 1;168(7):3444-50.


Cytokine production and apoptosis among T cells from patients under treatment for Plasmodium falciparum malaria.

Kemp K, Akanmori BD, Adabayeri V, Goka BQ, Kurtzhals JA, Behr C, Hviid L.

Clin Exp Immunol. 2002 Jan;127(1):151-7.


Complement binding to erythrocytes is associated with macrophage activation and reduced haemoglobin in Plasmodium falciparum malaria.

Goka BQ, Kwarko H, Kurtzhals JA, Gyan B, Ofori-Adjei E, Ohene SA, Hviid L, Akanmori BD, Neequaye J.

Trans R Soc Trop Med Hyg. 2001 Sep-Oct;95(5):545-9.


The importance of strict patient definition in studies of malaria pathogenesis.

Kurtzhals JA, Goka BQ, Akanmori BD, Hviid L.

Trends Parasitol. 2001 Jul;17(7):313-4. No abstract available.


Comparison of chloroquine with artesunate in the treatment of cerebral malaria in Ghanaian children.

Goka BQ, Adabayeri V, Ofori-Adjei E, Quarshie B, Asare-Odei G, Akanmori BD, Kurtzhals J, Ofori-Adjei D, Neequaye J.

J Trop Pediatr. 2001 Jun;47(3):165-9. doi: 10.1093/tropej/47.3.165.


Perturbation and proinflammatory type activation of V delta 1(+) gamma delta T cells in African children with Plasmodium falciparum malaria.

Hviid L, Kurtzhals JA, Adabayeri V, Loizon S, Kemp K, Goka BQ, Lim A, Mercereau-Puijalon O, Akanmori BD, Behr C.

Infect Immun. 2001 May;69(5):3190-6.


Haptoglobin 1-1 is associated with susceptibility to severe Plasmodium falciparum malaria.

Quaye IK, Ekuban FA, Goka BQ, Adabayeri V, Kurtzhals JA, Gyan B, Ankrah NA, Hviid L, Akanmori BD.

Trans R Soc Trop Med Hyg. 2000 Mar-Apr;94(2):216-9.


Distinct patterns of cytokine regulation in discrete clinical forms of Plasmodium falciparum malaria.

Akanmori BD, Kurtzhals JA, Goka BQ, Adabayeri V, Ofori MF, Nkrumah FK, Behr C, Hviid L.

Eur Cytokine Netw. 2000 Mar;11(1):113-8.


The cytokine balance in severe malarial anemia.

Kurtzhals JA, Akanmori BD, Goka BQ, Adabayeri V, Nkrumah FK, Behr C, Hviid L.

J Infect Dis. 1999 Nov;180(5):1753-5. No abstract available.


Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria.

Kurtzhals JA, Adabayeri V, Goka BQ, Akanmori BD, Oliver-Commey JO, Nkrumah FK, Behr C, Hviid L.

Lancet. 1998 Jun 13;351(9118):1768-72. Erratum in: Lancet 1998 Jul 18;352(9123):242. Lancet 1999 Mar 6;353(9155):848.


Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria.

Hviid L, Kurtzhals JA, Goka BQ, Oliver-Commey JO, Nkrumah FK, Theander TG.

Infect Immun. 1997 Oct;65(10):4090-3.

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