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Items: 30

1.

Mitochondrial dysfunctions in barth syndrome.

Ghosh S, Iadarola DM, Ball WB, Gohil VM.

IUBMB Life. 2019 Jul;71(7):791-801. doi: 10.1002/iub.2018. Epub 2019 Feb 11. Review.

PMID:
30746873
2.

Elesclomol restores mitochondrial function in genetic models of copper deficiency.

Soma S, Latimer AJ, Chun H, Vicary AC, Timbalia SA, Boulet A, Rahn JJ, Chan SSL, Leary SC, Kim BE, Gitlin JD, Gohil VM.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8161-8166. doi: 10.1073/pnas.1806296115. Epub 2018 Jul 23.

3.

Ethanolamine ameliorates mitochondrial dysfunction in cardiolipin-deficient yeast cells.

Basu Ball W, Baker CD, Neff JK, Apfel GL, Lagerborg KA, Žun G, Petrovič U, Jain M, Gohil VM.

J Biol Chem. 2018 Jul 13;293(28):10870-10883. doi: 10.1074/jbc.RA118.004014. Epub 2018 Jun 4.

4.

The role of nonbilayer phospholipids in mitochondrial structure and function.

Basu Ball W, Neff JK, Gohil VM.

FEBS Lett. 2018 Apr;592(8):1273-1290. doi: 10.1002/1873-3468.12887. Epub 2017 Nov 9. Review.

5.

Specific requirements of nonbilayer phospholipids in mitochondrial respiratory chain function and formation.

Baker CD, Basu Ball W, Pryce EN, Gohil VM.

Mol Biol Cell. 2016 Jul 15;27(14):2161-71. doi: 10.1091/mbc.E15-12-0865. Epub 2016 May 25.

6.

MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.

Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, Jaña F, Huang J, Barrero C, Rabinowitz JE, Luongo TS, Schumacher SM, Rockman ME, Dietrich A, Merali S, Caplan J, Stathopulos P, Ahima RS, Cheung JY, Houser SR, Koch WJ, Patel V, Gohil VM, Elrod JW, Rajan S, Madesh M.

Cell Rep. 2016 May 24;15(8):1673-85. doi: 10.1016/j.celrep.2016.04.050. Epub 2016 May 12.

7.

Design, synthesis and biological evaluation of 1,3,6-trisubstituted β-carboline derivatives for cytotoxic and anti-leishmanial potential.

Lunagariya NA, Gohil VM, Kushwah V, Neelagiri S, Jain S, Singh S, Bhutani KK.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):789-794. doi: 10.1016/j.bmcl.2015.12.095. Epub 2015 Dec 29.

PMID:
26791014
8.

Mitochondrial disease genes COA6, COX6B and SCO2 have overlapping roles in COX2 biogenesis.

Ghosh A, Pratt AT, Soma S, Theriault SG, Griffin AT, Trivedi PP, Gohil VM.

Hum Mol Genet. 2016 Feb 15;25(4):660-71. doi: 10.1093/hmg/ddv503. Epub 2015 Dec 15.

9.

Meclizine Preconditioning Protects the Kidney Against Ischemia-Reperfusion Injury.

Kishi S, Campanholle G, Gohil VM, Perocchi F, Brooks CR, Morizane R, Sabbisetti V, Ichimura T, Mootha VK, Bonventre JV.

EBioMedicine. 2015 Jul 29;2(9):1090-101. doi: 10.1016/j.ebiom.2015.07.035. eCollection 2015 Sep.

10.

Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency.

Ghosh A, Trivedi PP, Timbalia SA, Griffin AT, Rahn JJ, Chan SS, Gohil VM.

Hum Mol Genet. 2014 Jul 1;23(13):3596-606. doi: 10.1093/hmg/ddu069. Epub 2014 Feb 18.

11.

Mössbauer study and modeling of iron import and trafficking in human jurkat cells.

Jhurry ND, Chakrabarti M, McCormick SP, Gohil VM, Lindahl PA.

Biochemistry. 2013 Nov 12;52(45):7926-42. doi: 10.1021/bi401015t. Epub 2013 Nov 1.

12.

Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism.

Gohil VM, Zhu L, Baker CD, Cracan V, Yaseen A, Jain M, Clish CB, Brookes PS, Bakovic M, Mootha VK.

J Biol Chem. 2013 Dec 6;288(49):35387-95. doi: 10.1074/jbc.M113.489237. Epub 2013 Oct 19.

13.

Loss of cardiolipin leads to perturbation of mitochondrial and cellular iron homeostasis.

Patil VA, Fox JL, Gohil VM, Winge DR, Greenberg ML.

J Biol Chem. 2013 Jan 18;288(3):1696-705. doi: 10.1074/jbc.M112.428938. Epub 2012 Nov 28.

14.

Synthesis and anti-leishmanial activity of 1-aryl-β-carboline derivatives against Leishmania donovani.

Gohil VM, Brahmbhatt KG, Loiseau PM, Bhutani KK.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):3905-7. doi: 10.1016/j.bmcl.2012.04.115. Epub 2012 May 2.

PMID:
22608390
15.

Synthesis, biological evaluation and molecular docking of aryl hydrazines and hydrazides for anticancer activity.

Gohil VM, Agrawal SK, Saxena AK, Garg D, Gopimohan C, Bhutani KK.

Indian J Exp Biol. 2010 Mar;48(3):265-8.

PMID:
21046979
16.

Natural products drug discovery research in India: status and appraisal.

Bhutani KK, Gohil VM.

Indian J Exp Biol. 2010 Mar;48(3):199-207. Review.

PMID:
21046972
17.

Meclizine is neuroprotective in models of Huntington's disease.

Gohil VM, Offner N, Walker JA, Sheth SA, Fossale E, Gusella JF, MacDonald ME, Neri C, Mootha VK.

Hum Mol Genet. 2011 Jan 15;20(2):294-300. doi: 10.1093/hmg/ddq464. Epub 2010 Oct 25.

18.

MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake.

Perocchi F, Gohil VM, Girgis HS, Bao XR, McCombs JE, Palmer AE, Mootha VK.

Nature. 2010 Sep 16;467(7313):291-6. doi: 10.1038/nature09358. Epub 2010 Aug 8.

19.

Mitochondrial and nuclear genomic responses to loss of LRPPRC expression.

Gohil VM, Nilsson R, Belcher-Timme CA, Luo B, Root DE, Mootha VK.

J Biol Chem. 2010 Apr 30;285(18):13742-7. doi: 10.1074/jbc.M109.098400. Epub 2010 Mar 10.

20.

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis.

Gohil VM, Sheth SA, Nilsson R, Wojtovich AP, Lee JH, Perocchi F, Chen W, Clish CB, Ayata C, Brookes PS, Mootha VK.

Nat Biotechnol. 2010 Mar;28(3):249-55. doi: 10.1038/nbt.1606. Epub 2010 Feb 14.

21.

A computational screen for regulators of oxidative phosphorylation implicates SLIRP in mitochondrial RNA homeostasis.

Baughman JM, Nilsson R, Gohil VM, Arlow DH, Gauhar Z, Mootha VK.

PLoS Genet. 2009 Aug;5(8):e1000590. doi: 10.1371/journal.pgen.1000590. Epub 2009 Aug 14. Erratum in: PLoS Genet. 2010;6(3). doi: 10.1371/annotation/36fe7624-0904-46d4-a013-4be6195245c4.

22.

Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand.

Gohil VM, Greenberg ML.

J Cell Biol. 2009 Feb 23;184(4):469-72. doi: 10.1083/jcb.200901127. Review.

23.

Cellular functions of cardiolipin in yeast.

Joshi AS, Zhou J, Gohil VM, Chen S, Greenberg ML.

Biochim Biophys Acta. 2009 Jan;1793(1):212-8. doi: 10.1016/j.bbamcr.2008.07.024. Epub 2008 Aug 7. Review.

24.

Modulating TNF-alpha signaling with natural products.

Paul AT, Gohil VM, Bhutani KK.

Drug Discov Today. 2006 Aug;11(15-16):725-32. Review.

PMID:
16846800
25.
26.

Binding of 10-N-nonyl acridine orange to cardiolipin-deficient yeast cells: implications for assay of cardiolipin.

Gohil VM, Gvozdenovic-Jeremic J, Schlame M, Greenberg ML.

Anal Biochem. 2005 Aug 15;343(2):350-2. No abstract available.

PMID:
15963941
27.

Separation of yeast phospholipids using one-dimensional thin-layer chromatography.

Vaden DL, Gohil VM, Gu Z, Greenberg ML.

Anal Biochem. 2005 Mar 1;338(1):162-4. No abstract available.

PMID:
15707948
28.

Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent.

Gohil VM, Hayes P, Matsuyama S, Schägger H, Schlame M, Greenberg ML.

J Biol Chem. 2004 Oct 8;279(41):42612-8. Epub 2004 Jul 29.

29.

Absence of cardiolipin results in temperature sensitivity, respiratory defects, and mitochondrial DNA instability independent of pet56.

Zhong Q, Gohil VM, Ma L, Greenberg ML.

J Biol Chem. 2004 Jul 30;279(31):32294-300. Epub 2004 May 29.

30.

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