Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 208


Prolactin and its receptor as therapeutic targets in glioblastoma multiforme.

Asad AS, Nicola Candia AJ, Gonzalez N, Zuccato CF, Abt A, Orrillo SJ, Lastra Y, De Simone E, Boutillon F, Goffin V, Seilicovich A, Pisera DA, Ferraris MJ, Candolfi M.

Sci Rep. 2019 Dec 20;9(1):19578. doi: 10.1038/s41598-019-55860-x.


Author Correction: Collagen XXV promotes myoblast fusion during myogenic differentiation and muscle formation.

Gonçalves TJM, Boutillon F, Lefebvre S, Goffin V, Iwatsubo T, Wakabayashi T, Oury F, Armand AS.

Sci Rep. 2019 Nov 21;9(1):17519. doi: 10.1038/s41598-019-53896-7.


Prolactin Regulates Pain Responses via a Female-Selective Nociceptor-Specific Mechanism.

Patil M, Belugin S, Mecklenburg J, Wangzhou A, Paige C, Barba-Escobedo PA, Boyd JT, Goffin V, Grattan D, Boehm U, Dussor G, Price TJ, Akopian AN.

iScience. 2019 Oct 25;20:449-465. doi: 10.1016/j.isci.2019.09.039. Epub 2019 Oct 1.


Prolactin Promotes Fibrosis and Pancreatic Cancer Progression.

Tandon M, Coudriet GM, Criscimanna A, Socorro M, Eliliwi M, Singhi AD, Cruz-Monserrate Z, Bailey P, Lotze MT, Zeh H, Hu J, Goffin V, Gittes GK, Biankin AV, Esni F.

Cancer Res. 2019 Oct 15;79(20):5316-5327. doi: 10.1158/0008-5472.CAN-18-3064. Epub 2019 Aug 8.


Correction: Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents.

Gaston J, Cheradame L, Yvonnet V, Deas O, Poupon MF, Judde JG, Cairo S, Goffin V.

Oncotarget. 2019 Jun 25;10(41):4249-4251. doi: 10.18632/oncotarget.27042. eCollection 2019 Jun 25.


STAT5a/b Deficiency Delays, but does not Prevent, Prolactin-Driven Prostate Tumorigenesis in Mice.

Boutillon F, Pigat N, Sala LS, Reyes-Gomez E, Moriggl R, Guidotti JE, Goffin V.

Cancers (Basel). 2019 Jul 2;11(7). pii: E929. doi: 10.3390/cancers11070929.


Prolactin decreases LPS-induced inflammatory cytokines by inhibiting TLR-4/NFκB signaling in the human placenta.

Olmos-Ortiz A, Déciga-García M, Preciado-Martínez E, Bermejo-Martínez L, Flores-Espinosa P, Mancilla-Herrera I, Irles C, Helguera-Repetto AC, Quesada-Reyna B, Goffin V, Díaz L, Zaga-Clavellina V.

Mol Hum Reprod. 2019 Oct 28;25(10):660-667. doi: 10.1093/molehr/gaz038.


Prolactin receptor expression in mouse dorsal root ganglia neuronal subtypes is sex-dependent.

Patil M, Hovhannisyan AH, Wangzhou A, Mecklenburg J, Koek W, Goffin V, Grattan D, Boehm U, Dussor G, Price TJ, Akopian AN.

J Neuroendocrinol. 2019 Aug;31(8):e12759. doi: 10.1111/jne.12759. Epub 2019 Jul 4.


Combined Sabal and Urtica Extracts (WS® 1541) Exert Anti-proliferative and Anti-inflammatory Effects in a Mouse Model of Benign Prostate Hyperplasia.

Pigat N, Reyes-Gomez E, Boutillon F, Palea S, Barry Delongchamps N, Koch E, Goffin V.

Front Pharmacol. 2019 Mar 29;10:311. doi: 10.3389/fphar.2019.00311. eCollection 2019.


Collagen XXV promotes myoblast fusion during myogenic differentiation and muscle formation.

Gonçalves TJM, Boutillon F, Lefebvre S, Goffin V, Iwatsubo T, Wakabayashi T, Oury F, Armand AS.

Sci Rep. 2019 Apr 10;9(1):5878. doi: 10.1038/s41598-019-42296-6. Erratum in: Sci Rep. 2019 Nov 21;9(1):17519.


Paul Kelly, PhD (1943-2018).

Goffin V, Zingg HH, Sumida C, Touraine P, Friesen HG.

Pituitary. 2019 Feb;22(1):1-3. doi: 10.1007/s11102-018-0929-8. No abstract available.


JAK2/STAT5 Pathway Mediates Prolactin-Induced Apoptosis of Lactotropes.

de Dios N, Orrillo S, Irizarri M, Theas MS, Boutillon F, Candolfi M, Seilicovich A, Goffin V, Pisera D, Ferraris J.

Neuroendocrinology. 2019;108(2):84-97. doi: 10.1159/000494975. Epub 2018 Oct 30.


Do dietary calcium and vitamin D matter in men with prostate cancer?

Capiod T, Barry Delongchamps N, Pigat N, Souberbielle JC, Goffin V.

Nat Rev Urol. 2018 Jul;15(7):453-461. doi: 10.1038/s41585-018-0015-z. Review.


17β-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes.

Jallow F, Brockman JL, Helzer KT, Rugowski DE, Goffin V, Alarid ET, Schuler LA.

J Endocr Soc. 2018 Feb 26;2(3):293-309. doi: 10.1210/js.2017-00399. eCollection 2018 Mar 1.


Antiestrogen Therapy Increases Plasticity and Cancer Stemness of Prolactin-Induced ERα+ Mammary Carcinomas.

Shea MP, O'Leary KA, Fakhraldeen SA, Goffin V, Friedl A, Wisinski KB, Alexander CM, Schuler LA.

Cancer Res. 2018 Apr 1;78(7):1672-1684. doi: 10.1158/0008-5472.CAN-17-0985. Epub 2018 Jan 23.


Novel reagents for human prolactin research: large-scale preparation and characterization of prolactin receptor extracellular domain, non-pegylated and pegylated prolactin and prolactin receptor antagonist.

Oclon E, Solomon G, Hayouka Z, Salame TM, Goffin V, Gertler A.

Protein Eng Des Sel. 2018 Jan 1;31(1):7-16. doi: 10.1093/protein/gzx062.


ATM Is Required for the Prolactin-Induced HSP90-Mediated Increase in Cellular Viability and Clonogenic Growth After DNA Damage.

Karayazi Atici Ö, Urbanska A, Gopinathan SG, Boutillon F, Goffin V, Shemanko CS.

Endocrinology. 2018 Feb 1;159(2):907-930. doi: 10.1210/en.2017-00652.


A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours.

Sackmann Sala L, Boutillon F, Menara G, De Goyon-Pélard A, Leprévost M, Codzamanian J, Lister N, Pencik J, Clark A, Cagnard N, Bole-Feysot C, Moriggl R, Risbridger GP, Taylor RA, Kenner L, Guidotti JE, Goffin V.

J Pathol. 2017 Sep;243(1):51-64. doi: 10.1002/path.4924. Epub 2017 Jul 28.


Prolactin receptor targeting in breast and prostate cancers: New insights into an old challenge.

Goffin V.

Pharmacol Ther. 2017 Nov;179:111-126. doi: 10.1016/j.pharmthera.2017.05.009. Epub 2017 May 23. Review.


Alpha2-adrenoceptor agonists trigger prolactin signaling in breast cancer cells.

Castillo LF, Rivero EM, Goffin V, Lüthy IA.

Cell Signal. 2017 Jun;34:76-85. doi: 10.1016/j.cellsig.2017.03.003. Epub 2017 Mar 14.


Vitamin D3 Prevents Calcium-Induced Progression of Early-Stage Prostate Tumors by Counteracting TRPC6 and Calcium Sensing Receptor Upregulation.

Bernichtein S, Pigat N, Barry Delongchamps N, Boutillon F, Verkarre V, Camparo P, Reyes-Gomez E, Méjean A, Oudard SM, Lepicard EM, Viltard M, Souberbielle JC, Friedlander G, Capiod T, Goffin V.

Cancer Res. 2017 Jan 15;77(2):355-365. doi: 10.1158/0008-5472.CAN-16-0687. Epub 2016 Nov 22.


Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk.

Chakhtoura Z, Laki F, Bernadet M, Cherifi I, Chiche A, Pigat N, Bernichtein S, Courtillot C, Boutillon F, Bièche I, Vacher S, Tanguy ML, Bissery A, Grouthier V, Camparo P, Foretz M, Do Cruzeiro M, Pierre R, Rakotozafy F, Tichet J, Tejedor I, Guidotti JE, Sigal-Zafrani B, Goffin V, Touraine P.

J Clin Endocrinol Metab. 2016 Nov;101(11):4449-4460. Epub 2016 Aug 30.


Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents.

Gaston J, Cheradame L, Yvonnet V, Deas O, Poupon MF, Judde JG, Cairo S, Goffin V.

Oncotarget. 2016 Nov 22;7(47):77205-77224. doi: 10.18632/oncotarget.12858. Erratum in: Oncotarget. 2019 Jun 25;10(41):4249-4251.


The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation.

Tang MW, Reedquist KA, Garcia S, Fernandez BM, Codullo V, Vieira-Sousa E, Goffin V, Reuwer AQ, Twickler MT, Gerlag DM, Tak PP.

Rheumatology (Oxford). 2016 Dec;55(12):2248-2259. Epub 2016 Sep 10.


Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death.

Meléndez García R, Arredondo Zamarripa D, Arnold E, Ruiz-Herrera X, Noguez Imm R, Baeza Cruz G, Adán N, Binart N, Riesgo-Escovar J, Goffin V, Ordaz B, Peña-Ortega F, Martínez-Torres A, Clapp C, Thebault S.

EBioMedicine. 2016 May;7:35-49. doi: 10.1016/j.ebiom.2016.03.048. Epub 2016 Apr 20.


The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications.

Goffin V, Touraine P.

Expert Opin Ther Targets. 2015;19(9):1229-44. doi: 10.1517/14728222.2015.1053209. Epub 2015 Jun 11. Review.


Hypothalamic Prolactin Regulation of Luteinizing Hormone Secretion in the Female Rat.

Grachev P, Li XF, Goffin V, O'Byrne KT.

Endocrinology. 2015 Aug;156(8):2880-92. doi: 10.1210/en.2015-1040. Epub 2015 May 20.


High milk consumption does not affect prostate tumor progression in two mouse models of benign and neoplastic lesions.

Bernichtein S, Pigat N, Capiod T, Boutillon F, Verkarre V, Camparo P, Viltard M, Méjean A, Oudard S, Souberbielle JC, Friedlander G, Goffin V.

PLoS One. 2015 May 4;10(5):e0125423. doi: 10.1371/journal.pone.0125423. eCollection 2015.


Human and murine prostate basal/stem cells are not direct targets of prolactin.

Sackmann-Sala L, Angelergues A, Boutillon F, d'Acremont B, Maidenberg M, Oudard S, Goffin V.

Gen Comp Endocrinol. 2015 Sep 1;220:133-42. doi: 10.1016/j.ygcen.2015.04.007. Epub 2015 Apr 15.


Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes.

Haxholm GW, Nikolajsen LF, Olsen JG, Fredsted J, Larsen FH, Goffin V, Pedersen SF, Brooks AJ, Waters MJ, Kragelund BB.

Biochem J. 2015 Jun 15;468(3):495-506. doi: 10.1042/BJ20141243. Epub 2015 Apr 7.


Minireview: prolactin regulation of adult stem cells.

Sackmann-Sala L, Guidotti JE, Goffin V.

Mol Endocrinol. 2015 May;29(5):667-81. doi: 10.1210/me.2015-1022. Epub 2015 Mar 20. Review.


A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling.

Zhang C, Nygaard M, Haxholm GW, Boutillon F, Bernadet M, Hoos S, England P, Broutin I, Kragelund BB, Goffin V.

J Biol Chem. 2015 May 8;290(19):11890-904. doi: 10.1074/jbc.M115.639096. Epub 2015 Mar 17.


Anti-inflammatory properties of Lipidosterolic extract of Serenoa repens (Permixon®) in a mouse model of prostate hyperplasia.

Bernichtein S, Pigat N, Camparo P, Latil A, Viltard M, Friedlander G, Goffin V.

Prostate. 2015 May;75(7):706-22. doi: 10.1002/pros.22953. Epub 2015 Feb 14.


Residue 146 regulates prolactin receptor folding, basal activity and ligand-responsiveness: potential implications in breast tumorigenesis.

Zhang C, Cherifi I, Nygaard M, Haxholm GW, Bogorad RL, Bernadet M, England P, Broutin I, Kragelund BB, Guidotti JE, Goffin V.

Mol Cell Endocrinol. 2015 Feb 5;401:173-88. doi: 10.1016/j.mce.2014.12.006. Epub 2014 Dec 15.


Prolactin-induced prostate tumorigenesis.

Sackmann-Sala L, Goffin V.

Adv Exp Med Biol. 2015;846:221-42. doi: 10.1007/978-3-319-12114-7_10. Review.


Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

Brouwers B, de Faudeur G, Osipovich AB, Goyvaerts L, Lemaire K, Boesmans L, Cauwelier EJ, Granvik M, Pruniau VP, Van Lommel L, Van Schoors J, Stancill JS, Smolders I, Goffin V, Binart N, in't Veld P, Declercq J, Magnuson MA, Creemers JW, Schuit F, Schraenen A.

Cell Metab. 2014 Dec 2;20(6):979-90. doi: 10.1016/j.cmet.2014.11.004.


Prolactin-induced prostate tumorigenesis links sustained Stat5 signaling with the amplification of basal/stem cells and emergence of putative luminal progenitors.

Sackmann-Sala L, Chiche A, Mosquera-Garrote N, Boutillon F, Cordier C, Pourmir I, Pascual-Mathey L, Kessal K, Pigat N, Camparo P, Goffin V.

Am J Pathol. 2014 Nov;184(11):3105-19. doi: 10.1016/j.ajpath.2014.07.020. Epub 2014 Sep 3. Erratum in: Am J Pathol. 2014 Dec;184(12):3415.


Prolactin receptor antagonism uncouples lipids from atherosclerosis susceptibility.

van der Sluis RJ, van den Aardweg T, Reuwer AQ, Twickler MT, Boutillon F, Van Eck M, Goffin V, Hoekstra M.

J Endocrinol. 2014 Sep;222(3):341-50. doi: 10.1530/JOE-14-0343. Epub 2014 Jul 25.


Prolactin induces apoptosis of lactotropes in female rodents.

Ferraris J, Zárate S, Jaita G, Boutillon F, Bernadet M, Auffret J, Seilicovich A, Binart N, Goffin V, Pisera D.

PLoS One. 2014 May 23;9(5):e97383. doi: 10.1371/journal.pone.0097383. eCollection 2014.


Carboxypeptidase-D is elevated in prostate cancer and its anti-apoptotic activity is abolished by combined androgen and prolactin receptor targeting.

Thomas LN, Merrimen J, Bell DG, Rendon R, Goffin V, Too CK.

Prostate. 2014 May;74(7):732-42. doi: 10.1002/pros.22793. Epub 2014 Feb 24.


Calcium channels, external calcium concentration and cell proliferation.

Borowiec AS, Bidaux G, Pigat N, Goffin V, Bernichtein S, Capiod T.

Eur J Pharmacol. 2014 Sep 15;739:19-25. doi: 10.1016/j.ejphar.2013.10.072. Epub 2013 Nov 28. Review.


Prolactin signaling enhances colon cancer stemness by modulating Notch signaling in a Jak2-STAT3/ERK manner.

Neradugomma NK, Subramaniam D, Tawfik OW, Goffin V, Kumar TR, Jensen RA, Anant S.

Carcinogenesis. 2014 Apr;35(4):795-806. doi: 10.1093/carcin/bgt379. Epub 2013 Nov 21.


Use of prolactin receptor antagonist to better understand prolactin regulation of pituitary homeostasis.

Ferraris J, Bernichtein S, Pisera D, Goffin V.

Neuroendocrinology. 2013;98(3):171-9. doi: 10.1159/000354701. Epub 2013 Sep 19. Review.


Tumour necrosis factor alpha, interferon gamma and substance P are novel modulators of extrapituitary prolactin expression in human skin.

Langan EA, Vidali S, Pigat N, Funk W, Lisztes E, Bíró T, Goffin V, Griffiths CE, Paus R.

PLoS One. 2013 Apr 23;8(4):e60819. doi: 10.1371/journal.pone.0060819. Print 2013.


The Role of Prolactin in Bone Metastasis and Breast Cancer Cell-Mediated Osteoclast Differentiation.

Sutherland A, Forsyth A, Cong Y, Grant L, Juan TH, Lee JK, Klimowicz A, Petrillo SK, Hu J, Chan A, Boutillon F, Goffin V, Egan C, Tang PA, Cai L, Morris D, Magliocco A, Shemanko CS.

J Natl Cancer Inst. 2015 Nov 19;108(3). doi: 10.1093/jnci/djv338. Print 2016 Mar.


Fetal pancreas transplants are dependent on prolactin for their development and prevent type 1 diabetes in syngeneic but not allogeneic mice.

Fourcade G, Colombo BM, Grégoire S, Baeyens A, Rachdi L, Guez F, Goffin V, Scharfmann R, Salomon BL.

Diabetes. 2013 May;62(5):1646-55. doi: 10.2337/db12-0448. Epub 2013 Feb 19.


Prolactin regulates transcription of the ion uptake Na+/Cl- cotransporter (ncc) gene in zebrafish gill.

Breves JP, Serizier SB, Goffin V, McCormick SD, Karlstrom RO.

Mol Cell Endocrinol. 2013 Apr 30;369(1-2):98-106. doi: 10.1016/j.mce.2013.01.021. Epub 2013 Feb 6.


Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition.

Hesling C, Lopez J, Fattet L, Gonzalo P, Treilleux I, Blanchard D, Losson R, Goffin V, Pigat N, Puisieux A, Mikaelian I, Gillet G, Rimokh R.

Development. 2013 Jan 1;140(1):167-75. doi: 10.1242/dev.085068. Epub 2012 Nov 15.


The prolactin receptor mediates HOXA1-stimulated oncogenicity in mammary carcinoma cells.

Hou L, Xu B, Mohankumar KM, Goffin V, Perry JK, Lobie PE, Liu DX.

Int J Oncol. 2012 Dec;41(6):2285-95. doi: 10.3892/ijo.2012.1660. Epub 2012 Oct 15.


Supplemental Content

Loading ...
Support Center