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Items: 1 to 50 of 72

1.

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.

Haake K, Neehus AL, Buchegger T, Kühnel MP, Blank P, Philipp F, Oleaga-Quintas C, Schulz A, Grimley M, Goethe R, Jonigk D, Kalinke U, Boisson-Dupuis S, Casanova JL, Bustamante J, Lachmann N.

Cells. 2020 Feb 19;9(2). pii: E483. doi: 10.3390/cells9020483.

2.

Complete Genome Sequence of Mycobacterium avium subsp. avium Chester (DSM 44156).

Goethe R, Laarmann K, Spröer C, Bunk B.

Microbiol Resour Announc. 2020 Feb 13;9(7). pii: e01549-19. doi: 10.1128/MRA.01549-19.

3.

Assessing the visual and cognitive demands of in-vehicle information systems.

Strayer DL, Cooper JM, Goethe RM, McCarty MM, Getty DJ, Biondi F.

Cogn Res Princ Implic. 2019 Jun 21;4(1):18. doi: 10.1186/s41235-019-0166-3. Erratum in: Cogn Res Princ Implic. 2019 Aug 9;4(1):30.

4.

Type I interferon induced by TLR2-TLR4-MyD88-TRIF-IRF3 controls Mycobacterium abscessus subsp. abscessus persistence in murine macrophages via nitric oxide.

Ruangkiattikul N, Rys D, Abdissa K, Rohde M, Semmler T, Tegtmeyer PK, Kalinke U, Schwarz C, Lewin A, Goethe R.

Int J Med Microbiol. 2019 Jul;309(5):307-318. doi: 10.1016/j.ijmm.2019.05.007. Epub 2019 Jun 1.

PMID:
31178418
5.

Visual and Cognitive Demands of CarPlay, Android Auto, and Five Native Infotainment Systems.

Strayer DL, Cooper JM, McCarty MM, Getty DJ, Wheatley CL, Motzkus CJ, Goethe RM, Biondi F, Horrey WJ.

Hum Factors. 2019 Dec;61(8):1371-1386. doi: 10.1177/0018720819836575. Epub 2019 Apr 5.

PMID:
30950645
6.

The CARD9-Associated C-Type Lectin, Mincle, Recognizes La Crosse Virus (LACV) but Plays a Limited Role in Early Antiviral Responses against LACV.

Monteiro JT, Schön K, Ebbecke T, Goethe R, Ruland J, Baumgärtner W, Becker SC, Lepenies B.

Viruses. 2019 Mar 26;11(3). pii: E303. doi: 10.3390/v11030303.

7.

Presence of Infected Gr-1intCD11bhiCD11cint Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in Mycobacterium avium-Infected Mice.

Abdissa K, Nerlich A, Beineke A, Ruangkiattikul N, Pawar V, Heise U, Janze N, Falk C, Bruder D, Schleicher U, Bogdan C, Weiss S, Goethe R.

Front Immunol. 2018 Oct 16;9:2317. doi: 10.3389/fimmu.2018.02317. eCollection 2018.

8.

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages.

Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N.

Stem Cell Reports. 2018 Jan 9;10(1):7-16. doi: 10.1016/j.stemcr.2017.11.011. Epub 2017 Dec 14.

9.

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections.

Hetzel M, Mucci A, Blank P, Nguyen AHH, Schiller J, Halle O, Kühnel MP, Billig S, Meineke R, Brand D, Herder V, Baumgärtner W, Bange FC, Goethe R, Jonigk D, Förster R, Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N.

Blood. 2018 Feb 1;131(5):533-545. doi: 10.1182/blood-2017-10-812859. Epub 2017 Dec 12.

PMID:
29233822
10.

The Consensus from the Mycobacterium avium ssp. paratuberculosis (MAP) Conference 2017.

Kuenstner JT, Naser S, Chamberlin W, Borody T, Graham DY, McNees A, Hermon-Taylor J, Hermon-Taylor A, Dow CT, Thayer W, Biesecker J, Collins MT, Sechi LA, Singh SV, Zhang P, Shafran I, Weg S, Telega G, Rothstein R, Oken H, Schimpff S, Bach H, Bull T, Grant I, Ellingson J, Dahmen H, Lipton J, Gupta S, Chaubey K, Singh M, Agarwal P, Kumar A, Misri J, Sohal J, Dhama K, Hemati Z, Davis W, Hier M, Aitken J, Pierce E, Parrish N, Goldberg N, Kali M, Bendre S, Agrawal G, Baldassano R, Linn P, Sweeney RW, Fecteau M, Hofstaedter C, Potula R, Timofeeva O, Geier S, John K, Zayanni N, Malaty HM, Kahlenborn C, Kravitz A, Bulfon A, Daskalopoulos G, Mitchell H, Neilan B, Timms V, Cossu D, Mameli G, Angermeier P, Jelic T, Goethe R, Juste RA, Kuenstner L.

Front Public Health. 2017 Sep 27;5:208. doi: 10.3389/fpubh.2017.00208. eCollection 2017.

11.

cGAS-STING-TBK1-IRF3/7 induced interferon-β contributes to the clearing of non tuberculous mycobacterial infection in mice.

Ruangkiattikul N, Nerlich A, Abdissa K, Lienenklaus S, Suwandi A, Janze N, Laarmann K, Spanier J, Kalinke U, Weiss S, Goethe R.

Virulence. 2017 Oct 3;8(7):1303-1315. doi: 10.1080/21505594.2017.1321191. Epub 2017 Apr 19.

12.

CD4 T Cell Dependent Colitis Exacerbation Following Re-Exposure of Mycobacterium avium ssp. paratuberculosis.

Suwandi A, Bargen I, Pils MC, Krey M, Zur Lage S, Singh AK, Basler T, Falk CS, Seidler U, Hornef MW, Goethe R, Weiss S.

Front Cell Infect Microbiol. 2017 Mar 16;7:75. doi: 10.3389/fcimb.2017.00075. eCollection 2017.

13.

Transcriptomic Analysis Reveals Selective Metabolic Adaptation of Streptococcus suis to Porcine Blood and Cerebrospinal Fluid.

Koczula A, Jarek M, Visscher C, Valentin-Weigand P, Goethe R, Willenborg J.

Pathogens. 2017 Feb 15;6(1). pii: E7. doi: 10.3390/pathogens6010007.

14.

FlpS, the FNR-Like Protein of Streptococcus suis Is an Essential, Oxygen-Sensing Activator of the Arginine Deiminase System.

Willenborg J, Koczula A, Fulde M, de Greeff A, Beineke A, Eisenreich W, Huber C, Seitz M, Valentin-Weigand P, Goethe R.

Pathogens. 2016 Jul 21;5(3). pii: E51. doi: 10.3390/pathogens5030051.

15.

Metabolic traits of pathogenic streptococci.

Willenborg J, Goethe R.

FEBS Lett. 2016 Nov;590(21):3905-3919. doi: 10.1002/1873-3468.12317. Epub 2016 Aug 4. Review.

16.

C/EBPβ is a transcriptional key regulator of IL-36α in murine macrophages.

Nerlich A, Ruangkiattikul N, Laarmann K, Janze N, Dittrich-Breiholz O, Kracht M, Goethe R.

Biochim Biophys Acta. 2015 Aug;1849(8):966-78. doi: 10.1016/j.bbagrm.2015.06.002. Epub 2015 Jun 8.

PMID:
26066982
17.

FurA contributes to the oxidative stress response regulation of Mycobacterium avium ssp. paratuberculosis.

Eckelt E, Meißner T, Meens J, Laarmann K, Nerlich A, Jarek M, Weiss S, Gerlach GF, Goethe R.

Front Microbiol. 2015 Feb 6;6:16. doi: 10.3389/fmicb.2015.00016. eCollection 2015.

18.

Characterization of the pivotal carbon metabolism of Streptococcus suis serotype 2 under ex vivo and chemically defined in vitro conditions by isotopologue profiling.

Willenborg J, Huber C, Koczula A, Lange B, Eisenreich W, Valentin-Weigand P, Goethe R.

J Biol Chem. 2015 Feb 27;290(9):5840-54. doi: 10.1074/jbc.M114.619163. Epub 2015 Jan 9.

19.

Identification of a lineage specific zinc responsive genomic island in Mycobacterium avium ssp. paratuberculosis.

Eckelt E, Jarek M, Frömke C, Meens J, Goethe R.

BMC Genomics. 2014 Dec 6;15:1076. doi: 10.1186/1471-2164-15-1076.

20.

Establishment of a Cre recombinase based mutagenesis protocol for markerless gene deletion in Streptococcus suis.

Koczula A, Willenborg J, Bertram R, Takamatsu D, Valentin-Weigand P, Goethe R.

J Microbiol Methods. 2014 Dec;107:80-3. doi: 10.1016/j.mimet.2014.09.007. Epub 2014 Oct 1.

PMID:
25281472
21.

The Mycobacterium avium ssp. paratuberculosis specific mptD gene is required for maintenance of the metabolic homeostasis necessary for full virulence in mouse infections.

Meißner T, Eckelt E, Basler T, Meens J, Heinzmann J, Suwandi A, Oelemann WM, Trenkamp S, Holst O, Weiss S, Bunk B, Spröer C, Gerlach GF, Goethe R.

Front Cell Infect Microbiol. 2014 Aug 14;4:110. doi: 10.3389/fcimb.2014.00110. eCollection 2014.

22.

The arginine-ornithine antiporter ArcD contributes to biological fitness of Streptococcus suis.

Fulde M, Willenborg J, Huber C, Hitzmann A, Willms D, Seitz M, Eisenreich W, Valentin-Weigand P, Goethe R.

Front Cell Infect Microbiol. 2014 Aug 12;4:107. doi: 10.3389/fcimb.2014.00107. eCollection 2014.

23.

Experimental colitis is exacerbated by concomitant infection with Mycobacterium avium ssp. paratuberculosis.

Suwandi A, Bargen I, Roy B, Pils MC, Krey M, Zur Lage S, Basler T, Rohde M, Falk CS, Hornef MW, Goethe R, Weiss S.

Inflamm Bowel Dis. 2014 Nov;20(11):1962-71. doi: 10.1097/MIB.0000000000000157.

PMID:
25144571
24.

Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis.

Atreya R, Bülte M, Gerlach GF, Goethe R, Hornef MW, Köhler H, Meens J, Möbius P, Roeb E, Weiss S; ZooMAP Consortium.

Int J Med Microbiol. 2014 Oct;304(7):858-67. doi: 10.1016/j.ijmm.2014.07.006. Epub 2014 Jul 25. Review.

PMID:
25128370
25.

Characterization of multi-drug tolerant persister cells in Streptococcus suis.

Willenborg J, Willms D, Bertram R, Goethe R, Valentin-Weigand P.

BMC Microbiol. 2014 May 12;14:120. doi: 10.1186/1471-2180-14-120.

26.

Systemic and mucosal immune reactivity upon Mycobacterium avium ssp. paratuberculosis infection in mice.

Koc A, Bargen I, Suwandi A, Roderfeld M, Tschuschner A, Rath T, Gerlach GF, Hornef M, Goethe R, Weiss S, Roeb E.

PLoS One. 2014 Apr 11;9(4):e94624. doi: 10.1371/journal.pone.0094624. eCollection 2014.

27.

Role of capsule and suilysin in mucosal infection of complement-deficient mice with Streptococcus suis.

Seitz M, Beineke A, Singpiel A, Willenborg J, Dutow P, Goethe R, Valentin-Weigand P, Klos A, Baums CG.

Infect Immun. 2014 Jun;82(6):2460-71. doi: 10.1128/IAI.00080-14. Epub 2014 Mar 31.

28.

The CcpA regulon of Streptococcus suis reveals novel insights into the regulation of the streptococcal central carbon metabolism by binding of CcpA to two distinct binding motifs.

Willenborg J, de Greeff A, Jarek M, Valentin-Weigand P, Goethe R.

Mol Microbiol. 2014 Apr;92(1):61-83. doi: 10.1111/mmi.12537. Epub 2014 Mar 4.

29.

Subcytolytic effects of suilysin on interaction of Streptococcus suis with epithelial cells.

Seitz M, Baums CG, Neis C, Benga L, Fulde M, Rohde M, Goethe R, Valentin-Weigand P.

Vet Microbiol. 2013 Dec 27;167(3-4):584-91. doi: 10.1016/j.vetmic.2013.09.010. Epub 2013 Sep 13.

PMID:
24095145
30.

Mycobacterium avium subspecies impair dendritic cell maturation.

Basler T, Brumshagen C, Beineke A, Goethe R, Bäumer W.

Innate Immun. 2013 Oct;19(5):451-61. doi: 10.1177/1753425912470291. Epub 2013 Jan 2.

PMID:
23283733
31.

Metabolic adaptation of Mycobacterium avium subsp. paratuberculosis to the gut environment.

Weigoldt M, Meens J, Bange FC, Pich A, Gerlach GF, Goethe R.

Microbiology. 2013 Feb;159(Pt 2):380-391. doi: 10.1099/mic.0.062737-0. Epub 2012 Dec 6.

PMID:
23223439
32.

Bartonella spp. infection rate and B. grahamii in ticks.

Janecek E, Mietze A, Goethe R, Schnieder T, Strube C.

Emerg Infect Dis. 2012 Oct;18(10):1689-90. doi: 10.3201/eid1810.120390. No abstract available.

33.

Induction of matrix metalloproteinases and TLR2 and 6 in murine colon after oral exposure to Mycobacterium avium subsp. paratuberculosis.

Roderfeld M, Koc A, Rath T, Blöcher S, Tschuschner A, Akineden Ö, Fischer M, von Gerlach S, Goethe R, Eckelt E, Meens J, Bülte M, Basler T, Roeb E.

Microbes Infect. 2012 Jun;14(6):545-53. doi: 10.1016/j.micinf.2012.01.004. Epub 2012 Jan 16.

PMID:
22289202
34.

Occurrence of Bartonella henselae and Borrelia burgdorferi sensu lato co-infections in ticks collected from humans in Germany.

Mietze A, Strube C, Beyerbach M, Schnieder T, Goethe R.

Clin Microbiol Infect. 2011 Jun;17(6):918-20. doi: 10.1111/j.1469-0691.2010.03363.x. Epub 2010 Nov 10.

35.

Presence of intestinal Mycobacterium avium subspecies paratuberculosis (MAP) DNA is not associated with altered MMP expression in ulcerative colitis.

Rath T, Roderfeld M, Blöcher S, Rhode A, Basler T, Akineden Ö, Abdulmawjood A, Halwe JM, Goethe R, Bülte M, Roeb E.

BMC Gastroenterol. 2011 Apr 8;11:34. doi: 10.1186/1471-230X-11-34.

36.

Role of glucose and CcpA in capsule expression and virulence of Streptococcus suis.

Willenborg J, Fulde M, de Greeff A, Rohde M, Smith HE, Valentin-Weigand P, Goethe R.

Microbiology. 2011 Jun;157(Pt 6):1823-1833. doi: 10.1099/mic.0.046417-0. Epub 2011 Feb 24.

PMID:
21349980
37.

Differential proteome analysis of Mycobacterium avium subsp. paratuberculosis grown in vitro and isolated from cases of clinical Johne's disease.

Weigoldt M, Meens J, Doll K, Fritsch I, Möbius P, Goethe R, Gerlach GF.

Microbiology. 2011 Feb;157(Pt 2):557-565. doi: 10.1099/mic.0.044859-0. Epub 2010 Nov 4.

PMID:
21051485
38.

ArgR is an essential local transcriptional regulator of the arcABC operon in Streptococcus suis and is crucial for biological fitness in an acidic environment.

Fulde M, Willenborg J, de Greeff A, Benga L, Smith HE, Valentin-Weigand P, Goethe R.

Microbiology. 2011 Feb;157(Pt 2):572-582. doi: 10.1099/mic.0.043067-0. Epub 2010 Oct 14.

PMID:
20947575
39.

Combined MLST and AFLP typing of Bartonella henselae isolated from cats reveals new sequence types and suggests clonal evolution.

Mietze A, Morick D, Köhler H, Harrus S, Dehio C, Nolte I, Goethe R.

Vet Microbiol. 2011 Mar 24;148(2-4):238-45. doi: 10.1016/j.vetmic.2010.08.012. Epub 2010 Sep 21.

PMID:
20863631
40.

Reduced transcript stabilization restricts TNF-alpha expression in RAW264.7 macrophages infected with pathogenic mycobacteria: evidence for an involvement of lipomannan.

Basler T, Holtmann H, Abel J, Eckstein T, Baumer W, Valentin-Weigand P, Goethe R.

J Leukoc Biol. 2010 Jan;87(1):173-83. doi: 10.1189/jlb.0309207.

PMID:
19850884
41.

Internalization-dependent recognition of Mycobacterium avium ssp. paratuberculosis by intestinal epithelial cells.

Pott J, Basler T, Duerr CU, Rohde M, Goethe R, Hornef MW.

Cell Microbiol. 2009 Dec;11(12):1802-15. doi: 10.1111/j.1462-5822.2009.01372.x. Epub 2009 Aug 13.

PMID:
19681906
42.

Detection of Bartonella spp. in wild rodents in Israel using HRM real-time PCR.

Morick D, Baneth G, Avidor B, Kosoy MY, Mumcuoglu KY, Mintz D, Eyal O, Goethe R, Mietze A, Shpigel N, Harrus S.

Vet Microbiol. 2009 Nov 18;139(3-4):293-7. doi: 10.1016/j.vetmic.2009.06.019. Epub 2009 Jun 21.

PMID:
19595521
43.

Streptococcus suis bacterin and subunit vaccine immunogenicities and protective efficacies against serotypes 2 and 9.

Baums CG, Kock C, Beineke A, Bennecke K, Goethe R, Schröder C, Waldmann KH, Valentin-Weigand P.

Clin Vaccine Immunol. 2009 Feb;16(2):200-8. doi: 10.1128/CVI.00371-08. Epub 2008 Dec 24.

44.

Mycobacterium avium subspecies induce differential expression of pro-inflammatory mediators in a murine macrophage model: evidence for enhanced pathogenicity of Mycobacterium avium subspecies paratuberculosis.

Basler T, Geffers R, Weiss S, Valentin-Weigand P, Goethe R.

Immunobiology. 2008;213(9-10):879-88. doi: 10.1016/j.imbio.2008.07.009. Epub 2008 Sep 2.

PMID:
18926302
45.

Polysaccharide capsule and suilysin contribute to extracellular survival of Streptococcus suis co-cultivated with primary porcine phagocytes.

Benga L, Fulde M, Neis C, Goethe R, Valentin-Weigand P.

Vet Microbiol. 2008 Nov 25;132(1-2):211-9. doi: 10.1016/j.vetmic.2008.05.005. Epub 2008 May 14.

PMID:
18565698
46.
47.

Amplified fragment length polymorphism of Streptococcus suis strains correlates with their profile of virulence-associated genes and clinical background.

Rehm T, Baums CG, Strommenger B, Beyerbach M, Valentin-Weigand P, Goethe R.

J Med Microbiol. 2007 Jan;56(Pt 1):102-109. doi: 10.1099/jmm.0.46616-0.

PMID:
17172524
48.

Identification of a novel virulence determinant with serum opacification activity in Streptococcus suis.

Baums CG, Kaim U, Fulde M, Ramachandran G, Goethe R, Valentin-Weigand P.

Infect Immun. 2006 Nov;74(11):6154-62.

49.

Virulence-associated gene profiling of Streptococcus suis isolates by PCR.

Silva LM, Baums CG, Rehm T, Wisselink HJ, Goethe R, Valentin-Weigand P.

Vet Microbiol. 2006 Jun 15;115(1-3):117-27. Epub 2006 Jan 20.

PMID:
16431041
50.

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