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Items: 1 to 50 of 164

1.

A T-helper 1/interferon- gene signature is prognostic in the adjuvant setting of resectable high-risk melanoma but not in non-small cell lung cancer.

Dizier B, Callegaro A, Debois M, Dreno B, Hersey P, Gogas HJ, Kirkwood JM, Vansteenkiste JF, Sequist LV, Atanackovic D, Goeman J, van Houwelingen H, Salceda S, Wang F, Therasse P, Debruyne C, Spiessens B, Brichard VG, Louahed J, Ulloa-Montoya F.

Clin Cancer Res. 2019 Nov 15. pii: clincanres.3717.2018. doi: 10.1158/1078-0432.CCR-18-3717. [Epub ahead of print]

PMID:
31732522
2.

The harmonic mean p-value: Strong versus weak control, and the assumption of independence.

Goeman JJ, Rosenblatt JD, Nichols TE.

Proc Natl Acad Sci U S A. 2019 Oct 29. pii: 201909339. doi: 10.1073/pnas.1909339116. [Epub ahead of print] No abstract available.

PMID:
31662466
3.

Better-than-chance classification for signal detection.

Rosenblatt JD, Benjamini Y, Gilron R, Mukamel R, Goeman JJ.

Biostatistics. 2019 Oct 14. pii: kxz035. doi: 10.1093/biostatistics/kxz035. [Epub ahead of print]

PMID:
31612223
4.

Simultaneous Enrichment Analysis of all Possible Gene-sets: Unifying Self-Contained and Competitive Methods.

Ebrahimpoor M, Spitali P, Hettne K, Tsonaka R, Goeman J.

Brief Bioinform. 2019 Jul 9. pii: bbz074. doi: 10.1093/bib/bbz074. [Epub ahead of print]

PMID:
31297505
5.

Search for Early Pancreatic Cancer Blood Biomarkers in Five European Prospective Population Biobanks Using Metabolomics.

Fest J, Vijfhuizen LS, Goeman JJ, Veth O, Joensuu A, Perola M, Männistö S, Ness-Jensen E, Hveem K, Haller T, Tonisson N, Mikkel K, Metspalu A, van Duijn CM, Ikram A, Stricker BH, Ruiter R, van Eijck CHJ, van Ommen GB, ʼt Hoen PAC.

Endocrinology. 2019 Jul 1;160(7):1731-1742. doi: 10.1210/en.2019-00165.

6.

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine.

Onderwater GLJ, Ligthart L, Bot M, Demirkan A, Fu J, van der Kallen CJH, Vijfhuizen LS, Pool R, Liu J, Vanmolkot FHM, Beekman M, Wen KX, Amin N, Thesing CS, Pijpers JA, Kies DA, Zielman R, de Boer I, van Greevenbroek MMJ, Arts ICW, Milaneschi Y, Schram MT, Dagnelie PC, Franke L, Ikram MA, Ferrari MD, Goeman JJ, Slagboom PE, Wijmenga C, Stehouwer CDA, Boomsma DI, van Duijn CM, Penninx BW, 't Hoen PAC, Terwindt GM, van den Maagdenberg AMJM; BBMRI Metabolomics Consortium.

Neurology. 2019 Apr 16;92(16):e1899-e1911. doi: 10.1212/WNL.0000000000007313. Epub 2019 Apr 3.

7.

New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma.

Verhoeven J, Hulpia F, Kersemans K, Bolcaen J, De Lombaerde S, Goeman J, Descamps B, Hallaert G, Van den Broecke C, Deblaere K, Vanhove C, Van der Eycken J, Van Calenbergh S, Goethals I, De Vos F.

Sci Rep. 2019 Feb 27;9(1):2878. doi: 10.1038/s41598-019-40013-x.

8.

Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting.

Olie CS, Riaz M, Konietzny R, Charles PD, Pinto-Fernandez A, Kiełbasa SM, Aartsma-Rus A, Goeman JJ, Kessler BM, Raz V.

iScience. 2019 Feb 22;12:318-332. doi: 10.1016/j.isci.2019.01.024. Epub 2019 Jan 22.

9.

Tissue-sparing properties of Mohs micrographic surgery for infiltrative basal cell carcinoma.

van Kester MS, Goeman JJ, Genders RE.

J Am Acad Dermatol. 2019 Jun;80(6):1700-1703. doi: 10.1016/j.jaad.2019.01.057. Epub 2019 Jan 31.

PMID:
30710602
10.

A multicenter comparison of quantification methods for antisense oligonucleotide-induced DMD exon 51 skipping in Duchenne muscular dystrophy cell cultures.

Hiller M, Falzarano MS, Garcia-Jimenez I, Sardone V, Verheul RC, Popplewell L, Anthony K, Ruiz-Del-Yerro E, Osman H, Goeman JJ, Mamchaoui K, Dickson G, Ferlini A, Muntoni F, Aartsma-Rus A, Arechavala-Gomeza V, Datson NA, Spitali P.

PLoS One. 2018 Oct 2;13(10):e0204485. doi: 10.1371/journal.pone.0204485. eCollection 2018.

11.

Gaining power in multiple testing of interval hypotheses via conditionalization.

Ellis JL, Pecanka J, Goeman JJ.

Biostatistics. 2018 Sep 21. doi: 10.1093/biostatistics/kxy042. [Epub ahead of print]

PMID:
30247521
12.

Hommel's procedure in linear time.

Meijer RJ, Krebs TJP, Goeman JJ.

Biom J. 2019 Jan;61(1):73-82. doi: 10.1002/bimj.201700316. Epub 2018 Sep 5.

PMID:
30187522
13.

Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies.

van Meijgaarden KE, Khatri B, Smith SG, Drittij AMFH, de Paus RA, Goeman JJ, Ho MM, Dockrell HM, McShane H, Joosten SA, Ottenhoff THM.

PLoS One. 2018 Sep 4;13(9):e0201205. doi: 10.1371/journal.pone.0201205. eCollection 2018.

14.

Postmortem T2*- Weighted MRI Imaging of Cortical Iron Reflects Severity of Alzheimer's Disease.

Bulk M, Kenkhuis B, van der Graaf LM, Goeman JJ, Natté R, van der Weerd L.

J Alzheimers Dis. 2018;65(4):1125-1137. doi: 10.3233/JAD-180317.

15.

A test for detecting differential indirect trans effects between two groups of samples.

Chaturvedi N, Menezes RX, Goeman JJ, Wieringen WV.

Stat Appl Genet Mol Biol. 2018 Jul 31;17(5). pii: /j/sagmb.2018.17.issue-5/sagmb-2017-0058/sagmb-2017-0058.xml. doi: 10.1515/sagmb-2017-0058.

PMID:
30059350
16.

All-Resolutions Inference for brain imaging.

Rosenblatt JD, Finos L, Weeda WD, Solari A, Goeman JJ.

Neuroimage. 2018 Nov 1;181:786-796. doi: 10.1016/j.neuroimage.2018.07.060. Epub 2018 Jul 27.

PMID:
30056198
17.

Impact of congenital cytomegalovirus infection on transcriptomes from archived dried blood spots in relation to long-term clinical outcome.

Rovito R, Warnatz HJ, Kiełbasa SM, Mei H, Amstislavskiy V, Arens R, Yaspo ML, Lehrach H, Kroes ACM, Goeman JJ, Vossen ACTM.

PLoS One. 2018 Jul 19;13(7):e0200652. doi: 10.1371/journal.pone.0200652. eCollection 2018.

18.

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model.

Toonen LJA, Overzier M, Evers MM, Leon LG, van der Zeeuw SAJ, Mei H, Kielbasa SM, Goeman JJ, Hettne KM, Magnusson OT, Poirel M, Seyer A, 't Hoen PAC, van Roon-Mom WMC.

Mol Neurodegener. 2018 Jun 22;13(1):31. doi: 10.1186/s13024-018-0261-9.

19.

MAGE-A3 immunotherapeutic as adjuvant therapy for patients with resected, MAGE-A3-positive, stage III melanoma (DERMA): a double-blind, randomised, placebo-controlled, phase 3 trial.

Dreno B, Thompson JF, Smithers BM, Santinami M, Jouary T, Gutzmer R, Levchenko E, Rutkowski P, Grob JJ, Korovin S, Drucis K, Grange F, Machet L, Hersey P, Krajsova I, Testori A, Conry R, Guillot B, Kruit WHJ, Demidov L, Thompson JA, Bondarenko I, Jaroszek J, Puig S, Cinat G, Hauschild A, Goeman JJ, van Houwelingen HC, Ulloa-Montoya F, Callegaro A, Dizier B, Spiessens B, Debois M, Brichard VG, Louahed J, Therasse P, Debruyne C, Kirkwood JM.

Lancet Oncol. 2018 Jul;19(7):916-929. doi: 10.1016/S1470-2045(18)30254-7. Epub 2018 Jun 13.

PMID:
29908991
20.

Quantitative comparison of different iron forms in the temporal cortex of Alzheimer patients and control subjects.

Bulk M, van der Weerd L, Breimer W, Lebedev N, Webb A, Goeman JJ, Ward RJ, Huber M, Oosterkamp TH, Bossoni L.

Sci Rep. 2018 May 2;8(1):6898. doi: 10.1038/s41598-018-25021-7.

21.

Added Diagnostic Value of Cerebrospinal Fluid Biomarkers for Differential Dementia Diagnosis in an Autopsy-Confirmed Cohort.

Niemantsverdriet E, Feyen BFE, Le Bastard N, Martin JJ, Goeman J, De Deyn PP, Bjerke M, Engelborghs S.

J Alzheimers Dis. 2018;63(1):373-381. doi: 10.3233/JAD-170927.

22.

Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration.

Goossens J, Bjerke M, Van Mossevelde S, Van den Bossche T, Goeman J, De Vil B, Sieben A, Martin JJ, Cras P, De Deyn PP, Van Broeckhoven C, van der Zee J, Engelborghs S.

Alzheimers Res Ther. 2018 Mar 20;10(1):31. doi: 10.1186/s13195-018-0364-0.

23.

Cross-sectional serum metabolomic study of multiple forms of muscular dystrophy.

Spitali P, Hettne K, Tsonaka R, Sabir E, Seyer A, Hemerik JBA, Goeman JJ, Picillo E, Ergoli M, Politano L, Aartsma-Rus A.

J Cell Mol Med. 2018 Apr;22(4):2442-2448. doi: 10.1111/jcmm.13543. Epub 2018 Feb 14.

24.

Exact testing with random permutations.

Hemerik J, Goeman J.

Test (Madr). 2018;27(4):811-825. doi: 10.1007/s11749-017-0571-1. Epub 2017 Nov 30.

25.

Investigating the validity of the DN4 in a consecutive population of patients with chronic pain.

Timmerman H, Steegers MAH, Huygen FJPM, Goeman JJ, van Dasselaar NT, Schenkels MJ, Wilder-Smith OHG, Wolff AP, Vissers KCP.

PLoS One. 2017 Nov 30;12(11):e0187961. doi: 10.1371/journal.pone.0187961. eCollection 2017.

26.

Deep characterization of a common D4Z4 variant identifies biallelic DUX4 expression as a modifier for disease penetrance in FSHD2.

Lemmers RJ, van der Vliet PJ, Balog J, Goeman JJ, Arindrarto W, Krom YD, Straasheijm KR, Debipersad RD, Özel G, Sowden J, Snider L, Mul K, Sacconi S, van Engelen B, Tapscott SJ, Tawil R, van der Maarel SM.

Eur J Hum Genet. 2018 Jan;26(1):94-106. doi: 10.1038/s41431-017-0015-0. Epub 2017 Nov 21.

27.

Human papillomavirus and posttransplantation cutaneous squamous cell carcinoma: A multicenter, prospective cohort study.

Bouwes Bavinck JN, Feltkamp MCW, Green AC, Fiocco M, Euvrard S, Harwood CA, Nasir S, Thomson J, Proby CM, Naldi L, Diphoorn JCD, Venturuzzo A, Tessari G, Nindl I, Sampogna F, Abeni D, Neale RE, Goeman JJ, Quint KD, Halk AB, Sneek C, Genders RE, de Koning MNC, Quint WGV, Wieland U, Weissenborn S, Waterboer T, Pawlita M, Pfister H; EPI-HPV-UV-CA group.

Am J Transplant. 2018 May;18(5):1220-1230. doi: 10.1111/ajt.14537. Epub 2017 Nov 22.

28.

Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing.

Vogelaar IP, van der Post RS, van Krieken JHJ, Spruijt L, van Zelst-Stams WA, Kets CM, Lubinski J, Jakubowska A, Teodorczyk U, Aalfs CM, van Hest LP, Pinheiro H, Oliveira C, Jhangiani SN, Muzny DM, Gibbs RA, Lupski JR, de Ligt J, Vissers LELM, Hoischen A, Gilissen C, van de Vorst M, Goeman JJ, Schackert HK, Ranzani GN, Molinaro V, Gómez García EB, Hes FJ, Holinski-Feder E, Genuardi M, Ausems MGEM, Sijmons RH, Wagner A, van der Kolk LE, Bjørnevoll I, Høberg-Vetti H, van Kessel AG, Kuiper RP, Ligtenberg MJL, Hoogerbrugge N.

Eur J Hum Genet. 2017 Nov;25(11):1246-1252. doi: 10.1038/ejhg.2017.138. Epub 2017 Sep 6.

29.

The Cerebrospinal Fluid Aβ1-42/Aβ1-40 Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer's Disease in a Clinical Setting.

Niemantsverdriet E, Ottoy J, Somers C, De Roeck E, Struyfs H, Soetewey F, Verhaeghe J, Van den Bossche T, Van Mossevelde S, Goeman J, De Deyn PP, Mariën P, Versijpt J, Sleegers K, Van Broeckhoven C, Wyffels L, Albert A, Ceyssens S, Stroobants S, Staelens S, Bjerke M, Engelborghs S.

J Alzheimers Dis. 2017;60(2):561-576. doi: 10.3233/JAD-170327.

30.

Corrigenda to "Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents" [Bioorg Med Chem 24 (2016) 5172-5182].

Song L, Risseeuw MDP, Froeyen M, Karalic I, Goeman J, Cappoen D, Van der Eycken J, Cos P, Munier-Lehmann H, Van Calenbergh S.

Bioorg Med Chem. 2017 Oct 15;25(20):5889. doi: 10.1016/j.bmc.2017.08.023. Epub 2017 Aug 18. No abstract available.

PMID:
28826595
31.

Blinded histopathological characterisation of POLE exonuclease domain-mutant endometrial cancers: sheep in wolf's clothing.

Van Gool IC, Ubachs JEH, Stelloo E, de Kroon CD, Goeman JJ, Smit VTHBM, Creutzberg CL, Bosse T.

Histopathology. 2018 Jan;72(2):248-258. doi: 10.1111/his.13338. Epub 2017 Oct 10.

PMID:
28795426
32.

No added diagnostic value of non-phosphorylated tau fraction (p-taurel) in CSF as a biomarker for differential dementia diagnosis.

Goossens J, Bjerke M, Struyfs H, Niemantsverdriet E, Somers C, Van den Bossche T, Van Mossevelde S, De Vil B, Sieben A, Martin JJ, Cras P, Goeman J, De Deyn PP, Van Broeckhoven C, van der Zee J, Engelborghs S.

Alzheimers Res Ther. 2017 Jul 14;9(1):49. doi: 10.1186/s13195-017-0275-5.

33.

Robin Hood: A cost-efficient two-stage approach to large-scale simultaneous inference with non-homogeneous sparse effects.

Pecanka J, Goeman J.

Stat Appl Genet Mol Biol. 2017 Apr 25;16(2):107-132. doi: 10.1515/sagmb-2016-0039.

PMID:
28599402
34.

Involvement of the Glucocorticoid Receptor in Pro-inflammatory Transcription Factor Inhibition by Daucane Esters from Laserpitium zernyi.

Popović V, Goeman JL, Bougarne N, Eyckerman S, Heyerick A, De Bosscher K, Van der Eycken J.

J Nat Prod. 2017 May 26;80(5):1505-1513. doi: 10.1021/acs.jnatprod.7b00012. Epub 2017 May 10.

PMID:
28489375
35.

Contribution to the discussion of "A critical evaluation of the current 'p-value controversy"'.

Goeman JJ.

Biom J. 2017 Sep;59(5):884-885. doi: 10.1002/bimj.201700028. Epub 2017 Apr 25. No abstract available.

PMID:
28440065
36.

Atomic Layer Deposition of Pt Nanoparticles within the Cages of MIL-101: A Mild and Recyclable Hydrogenation Catalyst.

Leus K, Dendooven J, Tahir N, Ramachandran RK, Meledina M, Turner S, Van Tendeloo G, Goeman JL, Van der Eycken J, Detavernier C, Van Der Voort P.

Nanomaterials (Basel). 2016 Mar 9;6(3). pii: E45. doi: 10.3390/nano6030045.

37.

Daucane esters from laserwort (Laserpitium latifolium L.) inhibit cytokine and chemokine production in human lung epithelial cells.

Popović V, Goeman J, Thommis J, Heyerick A, Caroen J, Van der Eycken J, De Bosscher K.

Phytomedicine. 2017 Mar 15;26:28-36. doi: 10.1016/j.phymed.2017.01.001. Epub 2017 Jan 5.

PMID:
28257662
38.

Quantification of Phenotype Information Aids the Identification of Novel Disease Genes.

Vulto-van Silfhout AT, Gilissen C, Goeman JJ, Jansen S, van Amen-Hellebrekers CJM, van Bon BWM, Koolen DA, Sistermans EA, Brunner HG, de Brouwer APM, de Vries BBA.

Hum Mutat. 2017 May;38(5):594-599. doi: 10.1002/humu.23176. Epub 2017 Feb 2.

PMID:
28074630
39.

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.

van der Zee J, Gijselinck I, Van Mossevelde S, Perrone F, Dillen L, Heeman B, Bäumer V, Engelborghs S, De Bleecker J, Baets J, Gelpi E, Rojas-García R, Clarimón J, Lleó A, Diehl-Schmid J, Alexopoulos P, Perneczky R, Synofzik M, Just J, Schöls L, Graff C, Thonberg H, Borroni B, Padovani A, Jordanova A, Sarafov S, Tournev I, de Mendonça A, Miltenberger-Miltényi G, Simões do Couto F, Ramirez A, Jessen F, Heneka MT, Gómez-Tortosa E, Danek A, Cras P, Vandenberghe R, De Jonghe P, De Deyn PP, Sleegers K, Cruts M, Van Broeckhoven C, Goeman J, Nuytten D, Smets K, Robberecht W, Damme PV, Bleecker J, Santens P, Dermaut B, Versijpt J, Michotte A, Ivanoiu A, Deryck O, Bergmans B, Delbeck J, Bruyland M, Willems C, Salmon E, Pastor P, Ortega-Cubero S, Benussi L, Ghidoni R, Binetti G, Hernández I, Boada M, Ruiz A, Sorbi S, Nacmias B, Bagnoli S, Sorbi S, Sanchez-Valle R, Llado A, Santana I, Rosário Almeida M, Frisoni GB, Maetzler W, Matej R, Fraidakis MJ, Kovacs GG, Fabrizi GM, Testi S.

Hum Mutat. 2017 Mar;38(3):297-309. doi: 10.1002/humu.23161. Epub 2017 Jan 19.

40.

What (not) to expect when classifying rare events.

Blagus R, Goeman JJ.

Brief Bioinform. 2018 Mar 1;19(2):341-349. doi: 10.1093/bib/bbw107.

PMID:
27881432
41.

EEG Dominant Frequency Peak Differentiates Between Alzheimer's Disease and Frontotemporal Lobar Degeneration.

Goossens J, Laton J, Van Schependom J, Gielen J, Struyfs H, Van Mossevelde S, Van den Bossche T, Goeman J, De Deyn PP, Sieben A, Martin JJ, Van Broeckhoven C, van der Zee J, Engelborghs S, Nagels G.

J Alzheimers Dis. 2017;55(1):53-58.

PMID:
27636837
42.

Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents.

Song L, Risseeuw MDP, Froeyen M, Karalic I, Goeman J, Cappoen D, Van der Eycken J, Cos P, Munier-Lehmann H, Van Calenbergh S.

Bioorg Med Chem. 2016 Nov 1;24(21):5172-5182. doi: 10.1016/j.bmc.2016.08.041. Epub 2016 Aug 24. Erratum in: Bioorg Med Chem. 2017 Oct 15;25(20):5889.

43.

Common disease signatures from gene expression analysis in Huntington's disease human blood and brain.

Mina E, van Roon-Mom W, Hettne K, van Zwet E, Goeman J, Neri C, A C 't Hoen P, Mons B, Roos M.

Orphanet J Rare Dis. 2016 Aug 1;11(1):97. doi: 10.1186/s13023-016-0475-2.

44.

Plea for routinely presenting prediction intervals in meta-analysis.

IntHout J, Ioannidis JP, Rovers MM, Goeman JJ.

BMJ Open. 2016 Jul 12;6(7):e010247. doi: 10.1136/bmjopen-2015-010247.

45.

A global × global test for testing associations between two large sets of variables.

Chaturvedi N, de Menezes RX, Goeman JJ.

Biom J. 2017 Jan;59(1):145-158. doi: 10.1002/bimj.201500106. Epub 2016 May 25.

PMID:
27225065
46.

Minimally adaptive BH: A tiny but uniform improvement of the procedure of Benjamini and Hochberg.

Solari A, Goeman JJ.

Biom J. 2017 Jul;59(4):776-780. doi: 10.1002/bimj.201500253. Epub 2016 May 18.

PMID:
27192178
47.

Microarray Gene Expression Analysis to Evaluate Cell Type Specific Expression of Targets Relevant for Immunotherapy of Hematological Malignancies.

Pont MJ, Honders MW, Kremer AN, van Kooten C, Out C, Hiemstra PS, de Boer HC, Jager MJ, Schmelzer E, Vries RG, Al Hinai AS, Kroes WG, Monajemi R, Goeman JJ, Böhringer S, Marijt WA, Falkenburg JH, Griffioen M.

PLoS One. 2016 May 12;11(5):e0155165. doi: 10.1371/journal.pone.0155165. eCollection 2016.

48.

Epigenomic Analysis of Sézary Syndrome Defines Patterns of Aberrant DNA Methylation and Identifies Diagnostic Markers.

van Doorn R, Slieker RC, Boonk SE, Zoutman WH, Goeman JJ, Bagot M, Michel L, Tensen CP, Willemze R, Heijmans BT, Vermeer MH.

J Invest Dermatol. 2016 Sep;136(9):1876-1884. doi: 10.1016/j.jid.2016.03.042. Epub 2016 Apr 23. Review.

49.

A Cochran-Armitage-type and a score-free global test for multivariate ordinal data.

Jelizarow M, Mansmann U, Goeman JJ.

Stat Med. 2016 Jul 20;35(16):2754-69. doi: 10.1002/sim.6898. Epub 2016 Feb 28.

PMID:
26924287
50.

Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack.

Menezes RX, Mohammadi L, Goeman JJ, Boer JM.

BMC Bioinformatics. 2016 Feb 9;17:77. doi: 10.1186/s12859-016-0926-8.

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