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Items: 30

1.

Emerging Pharmacological Targets for the Treatment of Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Type 2 Diabetes.

Goedeke L, Perry RJ, Shulman GI.

Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:65-87. doi: 10.1146/annurev-pharmtox-010716-104727.

PMID:
30625285
2.

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents.

Goedeke L, Bates J, Vatner DF, Perry RJ, Wang T, Ramirez R, Li L, Ellis MW, Zhang D, Wong KE, Beysen C, Cline GW, Ray AS, Shulman GI.

Hepatology. 2018 Dec;68(6):2197-2211. doi: 10.1002/hep.30097.

PMID:
29790582
3.

Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis.

Aryal B, Singh AK, Zhang X, Varela L, Rotllan N, Goedeke L, Chaube B, Camporez JP, Vatner DF, Horvath TL, Shulman GI, Suárez Y, Fernández-Hernando C.

JCI Insight. 2018 Mar 22;3(6). pii: 97918. doi: 10.1172/jci.insight.97918. [Epub ahead of print]

4.

Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.

Vatner DF, Goedeke L, Camporez JG, Lyu K, Nasiri AR, Zhang D, Bhanot S, Murray SF, Still CD, Gerhard GS, Shulman GI, Samuel VT.

Diabetologia. 2018 Jun;61(6):1435-1446. doi: 10.1007/s00125-018-4579-1. Epub 2018 Mar 1.

PMID:
29497783
5.

Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance.

Price NL, Singh AK, Rotllan N, Goedeke L, Wing A, Canfrán-Duque A, Diaz-Ruiz A, Araldi E, Baldán Á, Camporez JP, Suárez Y, Rodeheffer MS, Shulman GI, de Cabo R, Fernández-Hernando C.

Cell Rep. 2018 Feb 20;22(8):2133-2145. doi: 10.1016/j.celrep.2018.01.074.

6.

Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes.

Willeit P, Skroblin P, Moschen AR, Yin X, Kaudewitz D, Zampetaki A, Barwari T, Whitehead M, Ramírez CM, Goedeke L, Rotllan N, Bonora E, Hughes AD, Santer P, Fernández-Hernando C, Tilg H, Willeit J, Kiechl S, Mayr M.

Diabetes. 2017 Feb;66(2):347-357. doi: 10.2337/db16-0731. Epub 2016 Nov 29.

7.

Micro-RNAs and High-Density Lipoprotein Metabolism.

Canfrán-Duque A, Lin CS, Goedeke L, Suárez Y, Fernández-Hernando C.

Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1076-84. doi: 10.1161/ATVBAHA.116.307028. Epub 2016 Apr 14. Review.

8.

miRNA regulation of LDL-cholesterol metabolism.

Goedeke L, Wagschal A, Fernández-Hernando C, Näär AM.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt B):2047-2052. doi: 10.1016/j.bbalip.2016.03.007. Epub 2016 Mar 9. Review.

9.

microRNAs in lipoprotein metabolism and cardiometabolic disorders.

Rotllan N, Price N, Pati P, Goedeke L, Fernández-Hernando C.

Atherosclerosis. 2016 Mar;246:352-60. doi: 10.1016/j.atherosclerosis.2016.01.025. Epub 2016 Jan 18. Review.

10.

miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice.

Goedeke L, Rotllan N, Ramírez CM, Aranda JF, Canfrán-Duque A, Araldi E, Fernández-Hernando A, Langhi C, de Cabo R, Baldán Á, Suárez Y, Fernández-Hernando C.

Atherosclerosis. 2015 Dec;243(2):499-509. doi: 10.1016/j.atherosclerosis.2015.09.033.

11.

Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis.

Wagschal A, Najafi-Shoushtari SH, Wang L, Goedeke L, Sinha S, deLemos AS, Black JC, Ramírez CM, Li Y, Tewhey R, Hatoum I, Shah N, Lu Y, Kristo F, Psychogios N, Vrbanac V, Lu YC, Hla T, de Cabo R, Tsang JS, Schadt E, Sabeti PC, Kathiresan S, Cohen DE, Whetstine J, Chung RT, Fernández-Hernando C, Kaplan LM, Bernards A, Gerszten RE, Näär AM.

Nat Med. 2015 Nov;21(11):1290-7. doi: 10.1038/nm.3980. Epub 2015 Oct 26.

12.

MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels.

Goedeke L, Rotllan N, Canfrán-Duque A, Aranda JF, Ramírez CM, Araldi E, Lin CS, Anderson NN, Wagschal A, de Cabo R, Horton JD, Lasunción MA, Näär AM, Suárez Y, Fernández-Hernando C.

Nat Med. 2015 Nov;21(11):1280-9. doi: 10.1038/nm.3949. Epub 2015 Oct 5.

13.

The miR-199-dynamin regulatory axis controls receptor-mediated endocytosis.

Aranda JF, Canfrán-Duque A, Goedeke L, Suárez Y, Fernández-Hernando C.

J Cell Sci. 2015 Sep 1;128(17):3197-209. doi: 10.1242/jcs.165233. Epub 2015 Jul 10.

14.

Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis.

Rotllan N, Chamorro-Jorganes A, Araldi E, Wanschel AC, Aryal B, Aranda JF, Goedeke L, Salerno AG, Ramírez CM, Sessa WC, Suárez Y, Fernández-Hernando C.

FASEB J. 2015 Feb;29(2):597-610. doi: 10.1096/fj.14-262097. Epub 2014 Nov 12.

15.

Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice.

Goedeke L, Salerno A, Ramírez CM, Guo L, Allen RM, Yin X, Langley SR, Esau C, Wanschel A, Fisher EA, Suárez Y, Baldán A, Mayr M, Fernández-Hernando C.

EMBO Mol Med. 2014 Sep;6(9):1133-41. doi: 10.15252/emmm.201404046.

16.

microRNA regulation of lipoprotein metabolism.

Goedeke L, Aranda JF, Fernández-Hernando C.

Curr Opin Lipidol. 2014 Aug;25(4):282-8. doi: 10.1097/MOL.0000000000000094. Review.

17.

MicroRNAs: a connection between cholesterol metabolism and neurodegeneration.

Goedeke L, Fernández-Hernando C.

Neurobiol Dis. 2014 Dec;72 Pt A:48-53. doi: 10.1016/j.nbd.2014.05.034. Epub 2014 Jun 5. Review.

18.

microRNAs and HDL life cycle.

Canfrán-Duque A, Ramírez CM, Goedeke L, Lin CS, Fernández-Hernando C.

Cardiovasc Res. 2014 Aug 1;103(3):414-22. doi: 10.1093/cvr/cvu140. Epub 2014 Jun 3. Review.

19.

RNA binding protein HuR regulates the expression of ABCA1.

Ramírez CM, Lin CS, Abdelmohsen K, Goedeke L, Yoon JH, Madrigal-Matute J, Martin-Ventura JL, Vo DT, Uren PJ, Penalva LO, Gorospe M, Fernández-Hernando C.

J Lipid Res. 2014 Jun;55(6):1066-76. doi: 10.1194/jlr.M044925. Epub 2014 Apr 11.

20.

MicroRNA 33 regulates glucose metabolism.

Ramírez CM, Goedeke L, Rotllan N, Yoon JH, Cirera-Salinas D, Mattison JA, Suárez Y, de Cabo R, Gorospe M, Fernández-Hernando C.

Mol Cell Biol. 2013 Aug;33(15):2891-902. doi: 10.1128/MCB.00016-13. Epub 2013 May 28.

21.

A regulatory role for microRNA 33* in controlling lipid metabolism gene expression.

Goedeke L, Vales-Lara FM, Fenstermaker M, Cirera-Salinas D, Chamorro-Jorganes A, Ramírez CM, Mattison JA, de Cabo R, Suárez Y, Fernández-Hernando C.

Mol Cell Biol. 2013 Jun;33(11):2339-52. doi: 10.1128/MCB.01714-12. Epub 2013 Apr 1.

22.

Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144.

Ramírez CM, Rotllan N, Vlassov AV, Dávalos A, Li M, Goedeke L, Aranda JF, Cirera-Salinas D, Araldi E, Salerno A, Wanschel A, Zavadil J, Castrillo A, Kim J, Suárez Y, Fernández-Hernando C.

Circ Res. 2013 Jun 7;112(12):1592-601. doi: 10.1161/CIRCRESAHA.112.300626. Epub 2013 Mar 21.

23.

MicroRNAs in metabolic disease.

Fernández-Hernando C, Ramírez CM, Goedeke L, Suárez Y.

Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):178-85. doi: 10.1161/ATVBAHA.112.300144. Review.

24.

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.

Rayner KJ, Esau CC, Hussain FN, McDaniel AL, Marshall SM, van Gils JM, Ray TD, Sheedy FJ, Goedeke L, Liu X, Khatsenko OG, Kaimal V, Lees CJ, Fernandez-Hernando C, Fisher EA, Temel RE, Moore KJ.

Nature. 2011 Oct 19;478(7369):404-7. doi: 10.1038/nature10486.

25.

Regulation of cholesterol homeostasis.

Goedeke L, Fernández-Hernando C.

Cell Mol Life Sci. 2012 Mar;69(6):915-30. doi: 10.1007/s00018-011-0857-5. Epub 2011 Oct 19. Review.

PMID:
22009455
26.

"Micromanaging" metabolic syndrome.

Ramírez CM, Goedeke L, Fernández-Hernando C.

Cell Cycle. 2011 Oct 1;10(19):3249-52. doi: 10.4161/cc.10.19.17558. Epub 2011 Oct 1.

27.

MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1.

Ramirez CM, Dávalos A, Goedeke L, Salerno AG, Warrier N, Cirera-Salinas D, Suárez Y, Fernández-Hernando C.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2707-14. doi: 10.1161/ATVBAHA.111.232066.

28.

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling.

Dávalos A, Goedeke L, Smibert P, Ramírez CM, Warrier NP, Andreo U, Cirera-Salinas D, Rayner K, Suresh U, Pastor-Pareja JC, Esplugues E, Fisher EA, Penalva LO, Moore KJ, Suárez Y, Lai EC, Fernández-Hernando C.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9232-7. doi: 10.1073/pnas.1102281108. Epub 2011 May 16.

29.

[Familial hemophagocytic reticulosis. A case report].

Maas B, Goedeke L, Roloff D, Drees N.

Monatsschr Kinderheilkd. 1974 Apr;122(4):164-8. German. No abstract available.

PMID:
4832030
30.

[THE HEREDITY OF HEMOPHILIA A].

BITTER K, GOEDEKE L, LANDBECK G, LENZ W.

Internist (Berl). 1963 Sep;4:397-400. German. No abstract available.

PMID:
14091459

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