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Items: 1 to 50 of 183

1.

US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.

PMID:
28267733
2.

Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo.

Conze DB, Albert L, Ferrick DA, Goeddel DV, Yeh WC, Mak T, Ashwell JD.

Mol Cell Biol. 2005 Apr;25(8):3348-56.

3.

The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis.

Novack DV, Yin L, Hagen-Stapleton A, Schreiber RD, Goeddel DV, Ross FP, Teitelbaum SL.

J Exp Med. 2003 Sep 1;198(5):771-81. Epub 2003 Aug 25.

4.

TNF-R1 signaling: a beautiful pathway.

Chen G, Goeddel DV.

Science. 2002 May 31;296(5573):1634-5. Review.

PMID:
12040173
5.
6.

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

Yin L, Wu L, Wesche H, Arthur CD, White JM, Goeddel DV, Schreiber RD.

Science. 2001 Mar 16;291(5511):2162-5.

7.

NF-kappa B activation by tumor necrosis factor and interleukin-1.

Cao Z, Tanaka M, Regnier C, Rothe M, Yamit-hezi A, Woronicz JD, Fuentes ME, Durnin MH, Dalrymple SA, Goeddel DV.

Cold Spring Harb Symp Quant Biol. 1999;64:473-83. Review. No abstract available.

PMID:
11232324
8.

T6BP, a TRAF6-interacting protein involved in IL-1 signaling.

Ling L, Goeddel DV.

Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9567-72.

9.

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development.

Yeh WC, Itie A, Elia AJ, Ng M, Shu HB, Wakeham A, Mirtsos C, Suzuki N, Bonnard M, Goeddel DV, Mak TW.

Immunity. 2000 Jun;12(6):633-42.

10.
11.

Robert A. Swanson (1947-99)

Goeddel DV, Levinson AD.

Nature. 2000 Jan 20;403(6767):264. No abstract available.

PMID:
10681237
12.

Signal transduction by tumor necrosis factor: the Parker B. Francis Lectureship.

Goeddel DV.

Chest. 1999 Jul;116(1 Suppl):69S-73S. Review. No abstract available.

PMID:
10424599
13.

UC-Genentech trial.

Henner D, Goeddel DV, Heyneker H, Itakura K, Tansura D.

Science. 1999 May 28;284(5419):1465. No abstract available.

PMID:
10383322
14.

Genentech stands by original data.

Henner DJ, Goeddel DV, Heyneker H, Itakura K, Yansura D, Ross M, Miozzari G.

Nature. 1999 May 27;399(6734):297-8. No abstract available.

PMID:
10360564
15.

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice.

Tanaka M, Fuentes ME, Yamaguchi K, Durnin MH, Dalrymple SA, Hardy KL, Goeddel DV.

Immunity. 1999 Apr;10(4):421-9.

16.

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling.

Lomaga MA, Yeh WC, Sarosi I, Duncan GS, Furlonger C, Ho A, Morony S, Capparelli C, Van G, Kaufman S, van der Heiden A, Itie A, Wakeham A, Khoo W, Sasaki T, Cao Z, Penninger JM, Paige CJ, Lacey DL, Dunstan CR, Boyle WJ, Goeddel DV, Mak TW.

Genes Dev. 1999 Apr 15;13(8):1015-24.

17.

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.

Jiang Y, Woronicz JD, Liu W, Goeddel DV.

Science. 1999 Jan 22;283(5401):543-6. Erratum in: Science 1999 Mar 19;283(5409):1852.

18.

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation.

Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr.

Science. 1998 Sep 11;281(5383):1680-3.

19.

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176.

Ling L, Cao Z, Goeddel DV.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3792-7.

20.

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis.

Yeh WC, de la Pompa JL, McCurrach ME, Shu HB, Elia AJ, Shahinian A, Ng M, Wakeham A, Khoo W, Mitchell K, El-Deiry WS, Lowe SW, Goeddel DV, Mak TW.

Science. 1998 Mar 20;279(5358):1954-8.

21.

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice.

Yeh WC, Shahinian A, Speiser D, Kraunus J, Billia F, Wakeham A, de la Pompa JL, Ferrick D, Hum B, Iscove N, Ohashi P, Rothe M, Goeddel DV, Mak TW.

Immunity. 1997 Nov;7(5):715-25.

22.

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK.

Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV.

Science. 1997 Oct 31;278(5339):866-9.

23.
24.

Identification and characterization of an IkappaB kinase.

Régnier CH, Song HY, Gao X, Goeddel DV, Cao Z, Rothe M.

Cell. 1997 Jul 25;90(2):373-83.

25.

Casper is a FADD- and caspase-related inducer of apoptosis.

Shu HB, Halpin DR, Goeddel DV.

Immunity. 1997 Jun;6(6):751-63.

26.

A death-domain-containing receptor that mediates apoptosis.

Kitson J, Raven T, Jiang YP, Goeddel DV, Giles KM, Pun KT, Grinham CJ, Brown R, Farrow SN.

Nature. 1996 Nov 28;384(6607):372-5.

PMID:
8934525
27.
29.

TRAF6 is a signal transducer for interleukin-1.

Cao Z, Xiong J, Takeuchi M, Kurama T, Goeddel DV.

Nature. 1996 Oct 3;383(6599):443-6.

PMID:
8837778
30.

RANTES secretion by gene-modified tumor cells results in loss of tumorigenicity in vivo: role of immune cell subpopulations.

Mulé JJ, Custer M, Averbook B, Yang JC, Weber JS, Goeddel DV, Rosenberg SA, Schall TJ.

Hum Gene Ther. 1996 Aug 20;7(13):1545-53.

31.
32.

I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction.

Rothe M, Xiong J, Shu HB, Williamson K, Goddard A, Goeddel DV.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8241-6.

33.

Physical mapping and genomic structure of the human TNFR2 gene.

Beltinger CP, White PS, Maris JM, Sulman EP, Jensen SJ, LePaslier D, Stallard BJ, Goeddel DV, de Sauvage FJ, Brodeur GM.

Genomics. 1996 Jul 1;35(1):94-100.

PMID:
8661109
34.
35.

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex.

Hsu H, Huang J, Shu HB, Baichwal V, Goeddel DV.

Immunity. 1996 Apr;4(4):387-96.

36.
37.

Tumor necrosis factor signaling mechanisms.

Goeddel DV.

Harvey Lect. 1996-1997;92:41-54. Review. No abstract available.

PMID:
15372742
38.

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.

Rothe M, Pan MG, Henzel WJ, Ayres TM, Goeddel DV.

Cell. 1995 Dec 29;83(7):1243-52.

39.

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40.

Rothe M, Sarma V, Dixit VM, Goeddel DV.

Science. 1995 Sep 8;269(5229):1424-7.

PMID:
7544915
40.
41.
42.

Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75.

Sheehan KC, Pinckard JK, Arthur CD, Dehner LP, Goeddel DV, Schreiber RD.

J Exp Med. 1995 Feb 1;181(2):607-17.

43.

Sequence, genomic organization, and chromosome localization of the mouse TRADD gene.

Pan MG, Xiong J, Copeland NG, Gilbert DJ, Jenkins NA, Goeddel DV.

J Inflamm. 1995-1996;46(3):168-75.

PMID:
8844497
44.

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice.

Erickson SL, de Sauvage FJ, Kikly K, Carver-Moore K, Pitts-Meek S, Gillett N, Sheehan KC, Schreiber RD, Goeddel DV, Moore MW.

Nature. 1994 Dec 8;372(6506):560-3.

PMID:
7990930
45.

Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism.

Skelton NJ, Garcia KC, Goeddel DV, Quan C, Burnier JP.

Biochemistry. 1994 Nov 22;33(46):13581-92.

PMID:
7947768
46.

Role of the 75-kDa tumor necrosis factor receptor: inhibition of early hematopoiesis.

Jacobsen FW, Rothe M, Rusten L, Goeddel DV, Smeland EB, Veiby OP, Slørdal L, Jacobsen SE.

Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10695-9.

47.
48.
49.

Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily.

Bennett BD, Wang Z, Kuang WJ, Wang A, Groopman JE, Goeddel DV, Scadden DT.

J Biol Chem. 1994 May 13;269(19):14211-8.

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