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Items: 1 to 50 of 52

1.

An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis.

Amedonu E, Brenker C, Barman S, Schreiber JA, Becker S, Peischard S, Strutz-Seebohm N, Strippel C, Dik A, Hartung HP, Budde T, Wiendl H, Strünker T, Wünsch B, Goebels N, Meuth SG, Seebohm G, Melzer N.

Front Neurol. 2019 Mar 1;10:178. doi: 10.3389/fneur.2019.00178. eCollection 2019.

2.

Infectious risk stratification in multiple sclerosis patients receiving immunotherapy.

Graf J, Leussink VI, Dehmel T, Ringelstein M, Goebels N, Adams O, MacKenzie CR, Warnke C, Feldt T, Lammerskitten A, Klotz L, Meuth S, Wiendl H, Hartung HP, Aktas O, Albrecht P.

Ann Clin Transl Neurol. 2017 Nov 24;4(12):909-914. doi: 10.1002/acn3.491. eCollection 2017 Dec.

3.

NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody.

Malviya M, Barman S, Golombeck KS, Planagumà J, Mannara F, Strutz-Seebohm N, Wrzos C, Demir F, Baksmeier C, Steckel J, Falk KK, Gross CC, Kovac S, Bönte K, Johnen A, Wandinger KP, Martín-García E, Becker AJ, Elger CE, Klöcker N, Wiendl H, Meuth SG, Hartung HP, Seebohm G, Leypoldt F, Maldonado R, Stadelmann C, Dalmau J, Melzer N, Goebels N.

Ann Clin Transl Neurol. 2017 Oct 3;4(11):768-783. doi: 10.1002/acn3.444. eCollection 2017 Nov.

4.

Dose-dependent inhibition of demyelination and microglia activation by IVIG.

Winter M, Baksmeier C, Steckel J, Barman S, Malviya M, Harrer-Kuster M, Hartung HP, Goebels N.

Ann Clin Transl Neurol. 2016 Sep 23;3(11):828-843. eCollection 2016 Nov.

5.

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases.

Weil MT, Möbius W, Winkler A, Ruhwedel T, Wrzos C, Romanelli E, Bennett JL, Enz L, Goebels N, Nave KA, Kerschensteiner M, Schaeren-Wiemers N, Stadelmann C, Simons M.

Cell Rep. 2016 Jul 12;16(2):314-322. doi: 10.1016/j.celrep.2016.06.008. Epub 2016 Jun 23.

6.

IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity.

Kocur M, Schneider R, Pulm AK, Bauer J, Kropp S, Gliem M, Ingwersen J, Goebels N, Alferink J, Prozorovski T, Aktas O, Scheu S.

Acta Neuropathol Commun. 2015 Apr 3;3:20. doi: 10.1186/s40478-015-0192-4.

7.

Axonal damage in papilledema linked to idiopathic intracranial hypertension as revealed by multifocal visual evoked potentials.

Hartmann CJ, Klistorner AI, Brandt AU, Schroeder K, Kolbe R, Cohn E, Goebels N, Guthoff R, Aktas O, Hartung HP, Albrecht P.

Clin Neurophysiol. 2015 Oct;126(10):2040-1. doi: 10.1016/j.clinph.2014.12.014. Epub 2014 Dec 27. No abstract available.

PMID:
25613033
8.

Interferon-β-related tumefactive brain lesion in a Caucasian patient with neuromyelitis optica and clinical stabilization with tocilizumab.

Harmel J, Ringelstein M, Ingwersen J, Mathys C, Goebels N, Hartung HP, Jarius S, Aktas O.

BMC Neurol. 2014 Dec 17;14:247. doi: 10.1186/s12883-014-0247-3.

9.

Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: implication for cellular immune responses.

Kieseier BC, Stüve O, Dehmel T, Goebels N, Leussink VI, Mausberg AK, Ringelstein M, Turowski B, Aktas O, Antoch G, Hartung HP.

JAMA Neurol. 2013 Mar 1;70(3):390-3.

PMID:
23599943
10.

Spinal cord diffusion-tensor imaging and motor-evoked potentials in multiple sclerosis patients: microstructural and functional asymmetry.

von Meyenburg J, Wilm BJ, Weck A, Petersen J, Gallus E, Mathys J, Schaetzle E, Schubert M, Boesiger P, von Meyenburg K, Goebels N, Kollias S.

Radiology. 2013 Jun;267(3):869-79. doi: 10.1148/radiol.13112776. Epub 2013 Mar 6.

PMID:
23468573
11.

Brachial amyotrophic diparesis associated with anti-Hu positive anterior horn cell disease and autonomic disorder.

Lee JI, Macht S, Albrecht P, Hartung HP, Goebels N.

J Neurol. 2013 Jan;260(1):301-2. doi: 10.1007/s00415-012-6711-3. Epub 2012 Nov 8. No abstract available.

PMID:
23135291
12.

Effects of dimethyl fumarate on neuroprotection and immunomodulation.

Albrecht P, Bouchachia I, Goebels N, Henke N, Hofstetter HH, Issberner A, Kovacs Z, Lewerenz J, Lisak D, Maher P, Mausberg AK, Quasthoff K, Zimmermann C, Hartung HP, Methner A.

J Neuroinflammation. 2012 Jul 7;9:163. doi: 10.1186/1742-2094-9-163.

13.

A case of relapsing-remitting neuroborreliosis? Challenges in the differential diagnosis of recurrent myelitis.

Albrecht P, Henke N, Lehmann HC, Macht S, Hefter H, Goebels N, Mackenzie C, Rupprecht TA, Fingerle V, Hartung HP, Methner A.

Case Rep Neurol. 2012 Jan;4(1):47-53. doi: 10.1159/000337223. Epub 2012 Mar 14.

14.

Atorvastatin added to interferon β for relapsing multiple sclerosis: a randomized controlled trial.

Kamm CP, El-Koussy M, Humpert S, Findling O, von Bredow F, Burren Y, Schwegler G, Schött D, Donati F, Müller M, Goebels N, Müller F, Slotboom J, Tettenborn B, Kappos L, Naegelin Y, Mattle HP.

J Neurol. 2012 Nov;259(11):2401-13. doi: 10.1007/s00415-012-6513-7. Epub 2012 May 9.

15.

Rituximab induces sustained reduction of pathogenic B cells in patients with peripheral nervous system autoimmunity.

Maurer MA, Rakocevic G, Leung CS, Quast I, Lukačišin M, Goebels N, Münz C, Wardemann H, Dalakas M, Lünemann JD.

J Clin Invest. 2012 Apr;122(4):1393-402. doi: 10.1172/JCI58743. Epub 2012 Mar 19.

16.

CNS live imaging reveals a new mechanism of myelination: the liquid croissant model.

Sobottka B, Ziegler U, Kaech A, Becher B, Goebels N.

Glia. 2011 Dec;59(12):1841-9. doi: 10.1002/glia.21228. Epub 2011 Sep 1.

PMID:
21887712
17.

Cladribine as a therapeutic option in multiple sclerosis.

Warnke C, Leussink VI, Goebels N, Aktas O, Boyko A, Kieseier BC, Hartung HP.

Clin Immunol. 2012 Jan;142(1):68-75. doi: 10.1016/j.clim.2011.05.009. Epub 2011 Jun 1. Review.

PMID:
21733757
18.

Clonally expanded plasma cells in the cerebrospinal fluid of patients with central nervous system autoimmune demyelination produce "oligoclonal bands".

von Büdingen HC, Gulati M, Kuenzle S, Fischer K, Rupprecht TA, Goebels N.

J Neuroimmunol. 2010 Jan 25;218(1-2):134-9. doi: 10.1016/j.jneuroim.2009.10.005. Epub 2009 Nov 8.

PMID:
19900722
19.

Another complication of natalizumab treatment? Taking the challenge.

Goebels N, Kappos L.

Ann Neurol. 2009 Sep;66(3):264-6. doi: 10.1002/ana.21842. No abstract available.

PMID:
19798646
20.

Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss.

Sobottka B, Harrer MD, Ziegler U, Fischer K, Wiendl H, Hünig T, Becher B, Goebels N.

Am J Pathol. 2009 Sep;175(3):1160-6. doi: 10.2353/ajpath.2009.090340. Epub 2009 Aug 21.

21.

Cross-reactive T-cell receptors in tumor and paraneoplastic target tissue.

Pellkofer HL, Voltz R, Goebels N, Hohlfeld R, Dornmair K.

Arch Neurol. 2009 May;66(5):655-8. doi: 10.1001/archneurol.2009.56.

PMID:
19433667
22.

Live imaging of remyelination after antibody-mediated demyelination in an ex-vivo model for immune mediated CNS damage.

Harrer MD, von Büdingen HC, Stoppini L, Alliod C, Pouly S, Fischer K, Goebels N.

Exp Neurol. 2009 Apr;216(2):431-8.

PMID:
19320002
23.

FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis.

Mehling M, Brinkmann V, Antel J, Bar-Or A, Goebels N, Vedrine C, Kristofic C, Kuhle J, Lindberg RL, Kappos L.

Neurology. 2008 Oct 14;71(16):1261-7. doi: 10.1212/01.wnl.0000327609.57688.ea.

PMID:
18852441
24.

Clonally expanded plasma cells in the cerebrospinal fluid of MS patients produce myelin-specific antibodies.

von Büdingen HC, Harrer MD, Kuenzle S, Meier M, Goebels N.

Eur J Immunol. 2008 Jul;38(7):2014-23. doi: 10.1002/eji.200737784. Erratum in: Eur J Immunol. 2008 Jul;38(7):2046-7.

25.

Therapeutic antibodies in multiple sclerosis.

Goebels N, Becher B.

Neurodegener Dis. 2008;5(1):5-7. No abstract available.

26.

Pathogen specificity and autoimmunity are distinct features of antigen-driven immune responses in neuroborreliosis.

Kuenzle S, von Büdingen HC, Meier M, Harrer MD, Urich E, Becher B, Goebels N.

Infect Immun. 2007 Aug;75(8):3842-7. Epub 2007 May 21.

27.
28.

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

Greter M, Heppner FL, Lemos MP, Odermatt BM, Goebels N, Laufer T, Noelle RJ, Becher B.

Nat Med. 2005 Mar;11(3):328-34. Epub 2005 Feb 27.

PMID:
15735653
29.

Escalating immunotherapy of multiple sclerosis--new aspects and practical application.

Rieckmann P, Toyka KV, Bassetti C, Beer K, Beer S, Buettner U, Chofflon M, Götschi-Fuchs M, Hess K, Kappos L, Kesselring J, Goebels N, Ludin HP, Mattle H, Schluep M, Vaney C, Baumhackl U, Berger T, Deisenhammer F, Fazekas F, Freimüller M, Kollegger H, Kristoferitsch W, Lassmann H, Markut H, Strasser-Fuchs S, Vass K, Altenkirch H, Bamborschke S, Baum K, Benecke R, Brück W, Dommasch D, Elias WG, Gass A, Gehlen W, Haas J, Haferkamp G, Hanefeld F, Hartung HP, Heesen C, Heidenreich F, Heitmann R, Hemmer B, Hense T, Hohlfeld R, Janzen RW, Japp G, Jung S, Jügelt E, Koehler J, Kölmel W, König N, Lowitzsch K, Manegold U, Melms A, Mertin J, Oschmann P, Petereit HF, Pette M, Pöhlau D, Pohl D, Poser S, Sailer M, Schmidt S, Schock G, Schulz M, Schwarz S, Seidel D, Sommer N, Stangel M, Stark E, Steinbrecher A, Tumani H, Voltz R, Weber F, Weinrich W, Weissert R, Wiendl H, Wiethölter H, Wildemann U, Zettl UK, Zipp F, Zschenderlein R, Izquierdo G, Kirjazovas A, Packauskas L, Miller D, Koncan Vracko B, Millers A, Orologas A, Panellus M, Sindic CJ, Bratic M, Svraka A, Vella NR, Stelmasiak Z, Selmaj K, Bartosik-Psujik H, Mitosek-Szewczyk K, Belniak E, Mochecka A, Bayas A, Chan A, Flachenecker P, Gold R, Kallmann B, Leussink V, Mäurer M, Ruprecht K, Stoll G, Weilbach FX; Multiple Sclerosis Therapy Consensus Group.

J Neurol. 2004 Nov;251(11):1329-39. Review.

PMID:
15592728
30.

Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood.

Skulina C, Schmidt S, Dornmair K, Babbe H, Roers A, Rajewsky K, Wekerle H, Hohlfeld R, Goebels N.

Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2428-33.

31.

T-cell-mediated autoimmunity: novel techniques to characterize autoreactive T-cell receptors.

Dornmair K, Goebels N, Weltzien HU, Wekerle H, Hohlfeld R.

Am J Pathol. 2003 Oct;163(4):1215-26. Review.

32.

Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis.

Hofbauer M, Wiesener S, Babbe H, Roers A, Wekerle H, Dornmair K, Hohlfeld R, Goebels N.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4090-5. Epub 2003 Mar 21.

33.

[Multiple sclerosis. Therapeutic nihilism is the wrong approach here].

Voltz R, Goebels N, Jarius S, Hohlfeld R.

MMW Fortschr Med. 2002 May 6;Suppl 2:52-7. German.

PMID:
12070851
34.

Intrathecal antibody production against Chlamydia pneumoniae in multiple sclerosis is part of a polyspecific immune response.

Derfuss T, Gürkov R, Then Bergh F, Goebels N, Hartmann M, Barz C, Wilske B, Autenrieth I, Wick M, Hohlfeld R, Meinl E.

Brain. 2001 Jul;124(Pt 7):1325-35.

PMID:
11408328
35.

Extensive myelitis associated with Mycoplasma pneumoniae infection: magnetic resonance imaging and clinical long-term follow-up.

Goebels N, Helmchen C, Abele-Horn M, Gasser T, Pfister HW.

J Neurol. 2001 Mar;248(3):204-8.

PMID:
11355154
36.

Inflammatory myopathy in POEMS syndrome.

Goebels N, Walther EU, Schaller M, Pongratz D, Mueller-Felber W.

Neurology. 2000 Nov 14;55(9):1413-4. No abstract available.

PMID:
11087797
37.

Dementia associated with vitamin B(12) deficiency: presentation of two cases and review of the literature.

Goebels N, Soyka M.

J Neuropsychiatry Clin Neurosci. 2000 Summer;12(3):389-94. Review.

PMID:
10956574
38.

Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction.

Babbe H, Roers A, Waisman A, Lassmann H, Goebels N, Hohlfeld R, Friese M, Schröder R, Deckert M, Schmidt S, Ravid R, Rajewsky K.

J Exp Med. 2000 Aug 7;192(3):393-404.

39.

Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence.

Goebels N, Hofstetter H, Schmidt S, Brunner C, Wekerle H, Hohlfeld R.

Brain. 2000 Mar;123 Pt 3:508-18.

PMID:
10686174
40.

[Intima media thickness in patients with vertebrobasilar and carotid stenosis/occlusions].

Oberseider J, Felten-Keil G, Schuler K, Goebels N, Hamann GF.

Ultraschall Med. 1999 Aug;20(4):144-9. German.

PMID:
10522356
41.

[Interferon beta-1b for treatment of secondary chronic progressive multiple sclerosis].

Zimmermann C, Walther EU, Goebels N, Lienert C, Kappos L, Hartung HP, Hohlfeld R.

Nervenarzt. 1999 Aug;70(8):759-63. German.

PMID:
10483579
42.

[Therapy of multiple sclerosis].

Bereznai B, Goebels N, Dang T, Voltz R, Walther E, Zimmermann C, Hohlfeld R.

Dtsch Med Wochenschr. 1999 May 14;124(19):595-9. Review. German. No abstract available.

PMID:
10365178
43.

Human muscle cells express a functional costimulatory molecule distinct from B7.1 (CD80) and B7.2 (CD86) in vitro and in inflammatory lesions.

Behrens L, Kerschensteiner M, Misgeld T, Goebels N, Wekerle H, Hohlfeld R.

J Immunol. 1998 Dec 1;161(11):5943-51. Erratum in: J Immunol 2000 May 15;164(10):5330.

44.

Cellular immune mechanisms in inflammatory myopathies.

Hohlfeld R, Engel AG, Goebels N, Behrens L.

Curr Opin Rheumatol. 1997 Nov;9(6):520-6. Review.

PMID:
9375281
45.

Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis.

Goebels N, Michaelis D, Engelhardt M, Huber S, Bender A, Pongratz D, Johnson MA, Wekerle H, Tschopp J, Jenne D, Hohlfeld R.

J Clin Invest. 1996 Jun 15;97(12):2905-10.

46.

The role of autoimmune T lymphocytes in the pathogenesis of multiple sclerosis.

Hohlfeld R, Meinl E, Weber F, Zipp F, Schmidt S, Sotgiu S, Goebels N, Voltz R, Spuler S, Iglesias A, et al.

Neurology. 1995 Jun;45(6 Suppl 6):S33-8. Review.

PMID:
7783909
47.

[Effect of muscular work on the myosonogram].

Reimers CD, Lochmüller H, Goebels N, Schlotter B, Stempfle U.

Ultraschall Med. 1995 Apr;16(2):79-83. German.

PMID:
7624761
48.

Myelin basic protein-specific T lymphocyte repertoire in multiple sclerosis. Complexity of the response and dominance of nested epitopes due to recruitment of multiple T cell clones.

Meinl E, Weber F, Drexler K, Morelle C, Ott M, Saruhan-Direskeneli G, Goebels N, Ertl B, Jechart G, Giegerich G, et al.

J Clin Invest. 1993 Dec;92(6):2633-43.

49.

Cellular mechanisms in inflammatory myopathies.

Hohlfeld R, Goebels N, Engel AG.

Baillieres Clin Neurol. 1993 Nov;2(3):617-35. Review.

PMID:
8156145
50.

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