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Items: 1 to 50 of 140

1.

DNA repair as a human biomonitoring tool: Comet assay approaches.

Azqueta A, Langie SAS, Boutet-Robinet E, Duthie S, Ladeira C, Møller P, Collins AR, Godschalk RWL; Working Group 5 of the hCOMET project (CA15132).

Mutat Res. 2019 Jul - Sep;781:71-87. doi: 10.1016/j.mrrev.2019.03.002. Epub 2019 Mar 6. Review.

PMID:
31416580
2.

Corrigendum to "Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell Gene mutation assays) and integration with somatic cell testing." [Mutat. Res. 832-833 (2018) 7-18].

Marchetti F, Aardema MJ, Beevers C, van Benthem J, Godschalk R, Williams A, Yauk CL, Young R, Douglas GR.

Mutat Res. 2019 Aug;844:70-71. doi: 10.1016/j.mrgentox.2019.05.018. Epub 2019 Jun 7. No abstract available.

3.

Corrigendum to "Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488" [Mutat. Res. 832-833 (2018) 19-28].

Marchetti F, Aardema MJ, Beevers C, van Benthem J, Douglas GR, Godschalk R, Yauk CL, Young R, Williams A.

Mutat Res. 2019 Aug;844:69. doi: 10.1016/j.mrgentox.2019.05.019. Epub 2019 Jun 12. No abstract available.

4.

Impact of Weight Loss Strategies on Obesity-Induced DNA Damage.

Setayesh T, Mišík M, Langie SAS, Godschalk R, Waldherr M, Bauer T, Leitner S, Bichler C, Prager G, Krupitza G, Haslberger A, Knasmüller S.

Mol Nutr Food Res. 2019 Sep;63(17):e1900045. doi: 10.1002/mnfr.201900045. Epub 2019 Jun 14.

5.

The association of maternal polyunsaturated fatty acids during pregnancy with social competence and problem behaviours at 7 years of age: The MEFAB cohort.

Tore EC, Gielen M, Antoniou EE, de Groot RHM, Godschalk RWL, Southwood TR, Smits L, Stratakis N, van de Wurff ISM, Zeegers MP.

Prostaglandins Leukot Essent Fatty Acids. 2019 May;144:1-9. doi: 10.1016/j.plefa.2019.04.002. Epub 2019 Apr 12.

PMID:
31088621
6.

Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet.

Rouschop SH, Karl T, Risch A, van Ewijk PA, Schrauwen-Hinderling VB, Opperhuizen A, van Schooten FJ, Godschalk RW.

J Lipid Res. 2019 Jul;60(7):1250-1259. doi: 10.1194/jlr.M092593. Epub 2019 May 7.

7.

Sirtuin 1 genetic variation, energy balance and colorectal cancer risk by sex and subsite in the Netherlands Cohort Study.

Simons CCJM, Schouten LJ, Godschalk RW, van Schooten FJ, van den Brandt PA, Weijenberg MP.

Sci Rep. 2018 Nov 8;8(1):16540. doi: 10.1038/s41598-018-34728-6.

8.

Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing.

Marchetti F, Aardema MJ, Beevers C, van Benthem J, Godschalk R, Williams A, Yauk CL, Young R, Douglas GR.

Mutat Res Genet Toxicol Environ Mutagen. 2018 Aug;832-833:7-18. doi: 10.1016/j.mrgentox.2018.05.021. Epub 2018 May 29. Erratum in: Mutat Res. 2019 Aug;844:70-71.

9.

Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488.

Marchetti F, Aardema M, Beevers C, van Benthem J, Douglas GR, Godschalk R, Yauk CL, Young R, Williams A.

Mutat Res Genet Toxicol Environ Mutagen. 2018 Aug;832-833:19-28. doi: 10.1016/j.mrgentox.2018.05.020. Epub 2018 Jun 1. Erratum in: Mutat Res. 2019 Aug;844:69.

10.

Bulky DNA adduct levels in normal-appearing colon mucosa, and the prevalence of colorectal adenomas.

Ho V, Peacock S, Massey TE, Godschalk RW, van Schooten FJ, Ashbury JE, Vanner SJ, King WD.

Biomarkers. 2018 Dec;23(8):735-741. doi: 10.1080/1354750X.2018.1485055. Epub 2018 Jul 23.

PMID:
29871536
11.

Polyunsaturated fatty acid status at birth, childhood growth, and cardiometabolic risk: a pooled analysis of the MEFAB and RHEA cohorts.

Stratakis N, Gielen M, Margetaki K, de Groot RHM, Apostolaki M, Chalkiadaki G, Vafeiadi M, Leventakou V, Karachaliou M, Godschalk RW, Kogevinas M, Stephanou EG, Zeegers MP, Chatzi L.

Eur J Clin Nutr. 2019 Apr;73(4):566-576. doi: 10.1038/s41430-018-0175-1. Epub 2018 May 16.

PMID:
29765163
12.

The Role of Genetic Variants in the Association between Dietary Acrylamide and Advanced Prostate Cancer in the Netherlands Cohort Study on Diet and Cancer.

Perloy A, Schouten LJ, van den Brandt PA, Godschalk R, van Schooten FJ, Hogervorst JGF.

Nutr Cancer. 2018 May-Jun;70(4):620-631. doi: 10.1080/01635581.2018.1460682. Epub 2018 Apr 26.

PMID:
29697282
13.

Dietary supplement intake during pregnancy; better safe than sorry?

de Boer A, Bast A, Godschalk R.

Regul Toxicol Pharmacol. 2018 Jun;95:442-447. doi: 10.1016/j.yrtph.2018.03.014. Epub 2018 Mar 20.

PMID:
29567330
14.

Interaction between dietary acrylamide intake and genetic variants for estrogen receptor-positive breast cancer risk.

Hogervorst JGF, van den Brandt PA, Godschalk RWL, van Schooten FJ, Schouten LJ.

Eur J Nutr. 2019 Apr;58(3):1033-1045. doi: 10.1007/s00394-018-1619-z. Epub 2018 Feb 14.

15.

PUFA status at birth and allergy-related phenotypes in childhood: a pooled analysis of the Maastricht Essential Fatty Acid Birth (MEFAB) and RHEA birth cohorts.

Stratakis N, Gielen M, Margetaki K, de Groot RHM, Apostolaki M, Chalkiadaki G, Vafeiadi M, Leventakou V, Godschalk RW, Kogevinas M, Stephanou EG, Zeegers MP, Chatzi L.

Br J Nutr. 2018 Jan;119(2):202-210. doi: 10.1017/S0007114517003348.

PMID:
29359683
16.

Inflammation and the chemical carcinogen benzo[a]pyrene: Partners in crime.

Shi Q, Godschalk RWL, van Schooten FJ.

Mutat Res. 2017 Oct;774:12-24. doi: 10.1016/j.mrrev.2017.08.003. Epub 2017 Aug 24. Review.

PMID:
29173495
17.

Paternal Exposure to Environmental Chemical Stress Affects Male Offspring's Hepatic Mitochondria.

Godschalk R, Remels A, Hoogendoorn C, van Benthem J, Luijten M, Duale N, Brunborg G, Olsen AK, Bouwman FG, Munnia A, Peluso M, Mariman E, van Schooten FJ.

Toxicol Sci. 2018 Mar 1;162(1):241-250. doi: 10.1093/toxsci/kfx246.

PMID:
29145655
18.

Associations between maternal long-chain polyunsaturated fatty acid concentrations and child cognition at 7 years of age: The MEFAB birth cohort.

Brouwer-Brolsma EM, van de Rest O, Godschalk R, Zeegers MPA, Gielen M, de Groot RHM.

Prostaglandins Leukot Essent Fatty Acids. 2017 Nov;126:92-97. doi: 10.1016/j.plefa.2017.09.012. Epub 2017 Sep 22.

PMID:
29031402
19.

Polyunsaturated fatty acid levels at birth and child-to-adult growth: Results from the MEFAB cohort.

Stratakis N, Gielen M, Margetaki K, Godschalk RW, van der Wurff I, Rouschop S, Ibrahim A, Antoniou E, Chatzi L, de Groot RHM, Zeegers MP.

Prostaglandins Leukot Essent Fatty Acids. 2017 Nov;126:72-78. doi: 10.1016/j.plefa.2017.09.004. Epub 2017 Sep 9.

PMID:
29031398
20.

Altered gene expression profiles in the lungs of benzo[a]pyrene-exposed mice in the presence of lipopolysaccharide-induced pulmonary inflammation.

Shi Q, Fijten RR, Spina D, Riffo Vasquez Y, Arlt VM, Godschalk RW, Van Schooten FJ.

Toxicol Appl Pharmacol. 2017 Dec 1;336:8-19. doi: 10.1016/j.taap.2017.09.023. Epub 2017 Oct 5.

21.

Exposure to meat-derived carcinogens and bulky DNA adduct levels in normal-appearing colon mucosa.

Ho V, Brunetti V, Peacock S, Massey TE, Godschalk RWL, van Schooten FJ, Ashbury JE, Vanner SJ, King WD.

Mutat Res. 2017 Sep;821:5-12. doi: 10.1016/j.mrgentox.2017.06.005. Epub 2017 Jul 4.

PMID:
28735743
22.

Interactions between dietary acrylamide intake and genes for ovarian cancer risk.

Hogervorst JGF, van den Brandt PA, Godschalk RWL, van Schooten FJ, Schouten LJ.

Eur J Epidemiol. 2017 May;32(5):431-441. doi: 10.1007/s10654-017-0244-0. Epub 2017 Apr 8.

23.

Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells.

Shi Q, Boots AW, Maas L, Veith C, van Kuijk K, Haenen GR, Godschalk RW, Van Schooten FJ.

Toxicology. 2017 Apr 15;381:64-74. doi: 10.1016/j.tox.2017.02.013. Epub 2017 Feb 24.

24.

The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice.

Langie SA, Cameron KM, Ficz G, Oxley D, Tomaszewski B, Gorniak JP, Maas LM, Godschalk RW, van Schooten FJ, Reik W, von Zglinicki T, Mathers JC.

Genes (Basel). 2017 Feb 17;8(2). pii: E75. doi: 10.3390/genes8020075.

25.

A systematic SNP selection approach to identify mechanisms underlying disease aetiology: linking height to post-menopausal breast and colorectal cancer risk.

Elands RJ, Simons CC, Riemenschneider M, Isaacs A, Schouten LJ, Verhage BA, Van Steen K, Godschalk RW, van den Brandt PA, Stoll M, Weijenberg MP.

Sci Rep. 2017 Jan 24;7:41034. doi: 10.1038/srep41034.

26.

Acidic cellular microenvironment modifies carcinogen-induced DNA damage and repair.

Shi Q, Maas L, Veith C, Van Schooten FJ, Godschalk RW.

Arch Toxicol. 2017 Jun;91(6):2425-2441. doi: 10.1007/s00204-016-1907-4. Epub 2016 Dec 22.

27.

Energy restriction at young age, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk in the Netherlands Cohort Study.

Simons CC, Schouten LJ, Godschalk RW, van Engeland M, van den Brandt PA, van Schooten FJ, Weijenberg MP.

Int J Cancer. 2017 Jan 15;140(2):272-284. doi: 10.1002/ijc.30439. Epub 2016 Oct 18.

28.

The influence of single nucleotide polymorphisms on the association between dietary acrylamide intake and endometrial cancer risk.

Hogervorst JG, van den Brandt PA, Godschalk RW, van Schooten FJ, Schouten LJ.

Sci Rep. 2016 Oct 7;6:34902. doi: 10.1038/srep34902.

29.

Potential role of gene-environment interactions in ion transport mechanisms in the etiology of renal cell cancer.

Deckers IA, van den Brandt PA, van Engeland M, van Schooten FJ, Godschalk RW, Keszei AP, Hogervorst JG, Schouten LJ.

Sci Rep. 2016 Sep 30;6:34262. doi: 10.1038/srep34262.

30.

Does Ataxia Telangiectasia Mutated (ATM) protect testicular and germ cell DNA integrity by regulating the redox status?

Godschalk RW, Vanhees K, Maas L, Drittij MJ, Pachen D, van Doorn-Khosrovani Sv, van Schooten FJ, Haenen GR.

Reprod Toxicol. 2016 Aug;63:169-73. doi: 10.1016/j.reprotox.2016.06.008. Epub 2016 Jun 16.

PMID:
27318254
31.

Association between prenatal and current exposure to selected LCPUFAs and school performance at age 7.

van der Wurff IS, Bakker EC, Hornstra G, Kirschner PA, Gielen M, Godschalk RW, Kremers S, Zeegers MP, de Groot RH.

Prostaglandins Leukot Essent Fatty Acids. 2016 May;108:22-9. doi: 10.1016/j.plefa.2016.03.005. Epub 2016 Mar 26.

PMID:
27154361
32.

Erratum: "Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother-Child Study (NewGeneris)".

Pedersen M, Mendez MA, Schoket B, Godschalk RW, Espinosa A, Landström A, Villanueva CM, Merlo DF, Fthenou E, Gracia-Lavedan E, van Schooten FJ, Hoek G, Brunborg G, Meltzer HM, Alexander J, Nielsen JK, Sunyer J, Wright J, Kovács K, de Hoogh K, Gutzkow KB, Hardie LJ, Chatzi L, Knudsen LE, Anna L, Ketzel M, Haugen M, Botsivali M, Nieuwenhuijsen MJ, Cirach M, Toledano MB, Smith RB, Fleming S, Agramunt S, Kyrtopoulos SA, Lukács V, Kleinjans JC, Segerbäck D, Kogevinas M.

Environ Health Perspect. 2016 Jan;124(1):A12. doi: 10.1289/ehp.124-A12. No abstract available.

33.

The oxidation of p-phenylenediamine, an ingredient used for permanent hair dyeing purposes, leads to the formation of hydroxyl radicals: Oxidative stress and DNA damage in human immortalized keratinocytes.

Zanoni TB, Hudari F, Munnia A, Peluso M, Godschalk RW, Zanoni MV, den Hartog GJ, Bast A, Barros SB, Maria-Engler SS, Hageman GJ, de Oliveira DP.

Toxicol Lett. 2015 Dec 15;239(3):194-204. doi: 10.1016/j.toxlet.2015.09.026. Epub 2015 Oct 9.

PMID:
26456176
34.

Inflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene.

Shi Q, Haenen GR, Maas L, Arlt VM, Spina D, Vasquez YR, Moonen E, Veith C, Van Schooten FJ, Godschalk RWL.

Arch Toxicol. 2016 Sep;90(9):2261-2273. doi: 10.1007/s00204-015-1593-7. Epub 2015 Oct 5.

35.

Genetic Variants in the Insulin-like Growth Factor Pathway and Colorectal Cancer Risk in the Netherlands Cohort Study.

Simons CC, Schouten LJ, Godschalk RW, van Engeland M, van den Brandt PA, van Schooten FJ, Weijenberg MP.

Sci Rep. 2015 Sep 18;5:14126. doi: 10.1038/srep14126.

36.

Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk.

Simons CC, Schouten LJ, Godschalk R, van Engeland M, van den Brandt PA, van Schooten FJ, Weijenberg MP.

Carcinogenesis. 2015 Sep;36(9):971-81. doi: 10.1093/carcin/bgv077. Epub 2015 May 29.

PMID:
26025909
37.

Gene-diet interactions in exposure to heterocyclic aromatic amines and bulky DNA adduct levels in blood leukocytes.

Ho V, Peacock S, Massey TE, Godschalk RW, van Schooten FJ, Chen J, King WD.

Environ Mol Mutagen. 2015 Aug;56(7):609-20. doi: 10.1002/em.21950. Epub 2015 May 22.

PMID:
26010176
38.

The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice.

Krais AM, Speksnijder EN, Melis JP, Indra R, Moserova M, Godschalk RW, van Schooten FJ, Seidel A, Kopka K, Schmeiser HH, Stiborova M, Phillips DH, Luijten M, Arlt VM.

Arch Toxicol. 2016 Apr;90(4):839-51. doi: 10.1007/s00204-015-1531-8. Epub 2015 May 21.

39.

Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene.

Arlt VM, Krais AM, Godschalk RW, Riffo-Vasquez Y, Mrizova I, Roufosse CA, Corbin C, Shi Q, Frei E, Stiborova M, van Schooten FJ, Phillips DH, Spina D.

Toxicol Sci. 2015 Aug;146(2):213-25. doi: 10.1093/toxsci/kfv086. Epub 2015 Apr 23.

40.

Canonical autophagy does not contribute to cellular radioresistance.

Schaaf MB, Jutten B, Keulers TG, Savelkouls KG, Peeters HJ, van den Beucken T, van Schooten FJ, Godschalk RW, Vooijs M, Rouschop KM.

Radiother Oncol. 2015 Mar;114(3):406-12. doi: 10.1016/j.radonc.2015.02.019. Epub 2015 Mar 13.

PMID:
25779723
41.

Environmental carcinogens and mutational pathways in atherosclerosis.

Pulliero A, Godschalk R, Andreassi MG, Curfs D, Van Schooten FJ, Izzotti A.

Int J Hyg Environ Health. 2015 May;218(3):293-312. doi: 10.1016/j.ijheh.2015.01.007. Epub 2015 Feb 7. Review.

PMID:
25704189
42.

Environmental, dietary, maternal, and fetal predictors of bulky DNA adducts in cord blood: a European mother-child study (NewGeneris).

Pedersen M, Mendez MA, Schoket B, Godschalk RW, Espinosa A, Landström A, Villanueva CM, Merlo DF, Fthenou E, Gracia-Lavedan E, van Schooten FJ, Hoek G, Brunborg G, Meltzer HM, Alexander J, Nielsen JK, Sunyer J, Wright J, Kovács K, de Hoogh K, Gutzkow KB, Hardie LJ, Chatzi L, Knudsen LE, Anna L, Ketzel M, Haugen M, Botsivali M, Nieuwenhuijsen MJ, Cirach M, Toledano MB, Smith RB, Fleming S, Agramunt S, Kyrtopoulos SA, Lukács V, Kleinjans JC, Segerbäck D, Kogevinas M.

Environ Health Perspect. 2015 Apr;123(4):374-80. doi: 10.1289/ehp.1408613. Epub 2015 Jan 27. Erratum in: Environ Health Perspect. 2016 Jan;124(1):A12.

43.

The shifting perception on antioxidants: the case of vitamin E and β-carotene.

Vrolijk MF, Opperhuizen A, Jansen EH, Godschalk RW, Van Schooten FJ, Bast A, Haenen GR.

Redox Biol. 2015;4:272-8. doi: 10.1016/j.redox.2014.12.017. Epub 2015 Jan 16. Review.

44.

DNA from nails for genetic analyses in large-scale epidemiologic studies.

Hogervorst JG, Godschalk RW, van den Brandt PA, Weijenberg MP, Verhage BA, Jonkers L, Goessens J, Simons CC, Vermeesch JR, van Schooten FJ, Schouten LJ.

Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2703-12. doi: 10.1158/1055-9965.EPI-14-0552.

45.

Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene.

Schults MA, Sanen K, Godschalk RW, Theys J, van Schooten FJ, Chiu RK.

Mutagenesis. 2014 Nov;29(6):481-7. doi: 10.1093/mutage/geu034. Epub 2014 Sep 8.

PMID:
25199627
46.

Polymorphisms in genes of the renin-angiotensin-aldosterone system and renal cell cancer risk: interplay with hypertension and intakes of sodium, potassium and fluid.

Deckers IA, van den Brandt PA, van Engeland M, van Schooten FJ, Godschalk RW, Keszei AP, Schouten LJ.

Int J Cancer. 2015 Mar 1;136(5):1104-16. doi: 10.1002/ijc.29060. Epub 2014 Jul 10.

47.

Association between polyunsaturated fatty acid concentrations in maternal plasma phospholipids during pregnancy and offspring adiposity at age 7: the MEFAB cohort.

de Vries PS, Gielen M, Rizopoulos D, Rump P, Godschalk R, Hornstra G, Zeegers MP.

Prostaglandins Leukot Essent Fatty Acids. 2014 Sep;91(3):81-5. doi: 10.1016/j.plefa.2014.04.002. Epub 2014 Apr 25.

PMID:
24813643
48.

Redox and epigenetic regulation of the APE1 gene in the hippocampus of piglets: The effect of early life exposures.

Langie SA, Kowalczyk P, Tomaszewski B, Vasilaki A, Maas LM, Moonen EJ, Palagani A, Godschalk RW, Tudek B, van Schooten FJ, Berghe WV, Zabielski R, Mathers JC.

DNA Repair (Amst). 2014 Jun;18:52-62. doi: 10.1016/j.dnarep.2014.03.011. Epub 2014 Apr 29.

PMID:
24794400
49.

Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories.

Godschalk RW, Ersson C, Stępnik M, Ferlińska M, Palus J, Teixeira JP, Costa S, Jones GD, Higgins JA, Kain J, Möller L, Forchhammer L, Loft S, Lorenzo Y, Collins AR, van Schooten FJ, Laffon B, Valdiglesias V, Cooke M, Mistry V, Karbaschi M, Phillips DH, Sozeri O, Routledge MN, Nelson-Smith K, Riso P, Porrini M, López de Cerain A, Azqueta A, Matullo G, Allione A, Møller P.

Mutagenesis. 2014 Jul;29(4):241-9. doi: 10.1093/mutage/geu012. Epub 2014 Apr 15.

PMID:
24737269
50.

Micronuclei in cord blood lymphocytes and associations with biomarkers of exposure to carcinogens and hormonally active factors, gene polymorphisms, and gene expression: the NewGeneris cohort.

Merlo DF, Agramunt S, Anna L, Besselink H, Botsivali M, Brady NJ, Ceppi M, Chatzi L, Chen B, Decordier I, Farmer PB, Fleming S, Fontana V, Försti A, Fthenou E, Gallo F, Georgiadis P, Gmuender H, Godschalk RW, Granum B, Hardie LJ, Hemminki K, Hochstenbach K, Knudsen LE, Kogevinas M, Kovács K, Kyrtopoulos SA, Løvik M, Nielsen JK, Nygaard UC, Pedersen M, Rydberg P, Schoket B, Segerbäck D, Singh R, Sunyer J, Törnqvist M, van Loveren H, van Schooten FJ, Vande Loock K, von Stedingk H, Wright J, Kleinjans JC, Kirsch-Volders M, van Delft JH; NewGeneris Consortium.

Environ Health Perspect. 2014 Feb;122(2):193-200. doi: 10.1289/ehp.1206324. Epub 2013 Nov 19.

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