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NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte.

Udden SN, Kwak YT, Godfrey V, Khan MAW, Khan S, Loof N, Peng L, Zhu H, Zaki H.

Elife. 2019 Apr 16;8. pii: e40396. doi: 10.7554/eLife.40396.


Cytosolic Nucleic Acid Sensors in Inflammatory and Autoimmune Disorders.

Khan S, Godfrey V, Zaki MH.

Int Rev Cell Mol Biol. 2019;344:215-253. doi: 10.1016/bs.ircmb.2018.10.002. Epub 2018 Dec 3.


Development of outbred CD1 mouse colonies with distinct standardized gut microbiota profiles for use in complex microbiota targeted studies.

Hart ML, Ericsson AC, Lloyd KCK, Grimsrud KN, Rogala AR, Godfrey VL, Nielsen JN, Franklin CL.

Sci Rep. 2018 Jul 4;8(1):10107. doi: 10.1038/s41598-018-28448-0.


Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking.

Porrello A, Leslie PL, Harrison EB, Gorentla BK, Kattula S, Ghosh SK, Azam SH, Holtzhausen A, Chao YL, Hayward MC, Waugh TA, Bae S, Godfrey V, Randell SH, Oderup C, Makowski L, Weiss J, Wilkerson MD, Hayes DN, Earp HS, Baldwin AS, Wolberg AS, Pecot CV.

Nat Commun. 2018 May 18;9(1):1988. doi: 10.1038/s41467-018-04355-w.


Lanthionine Synthetase C-Like 2 Modulates Immune Responses to Influenza Virus Infection.

Leber A, Bassaganya-Riera J, Tubau-Juni N, Zoccoli-Rodriguez V, Lu P, Godfrey V, Kale S, Hontecillas R.

Front Immunol. 2017 Feb 21;8:178. doi: 10.3389/fimmu.2017.00178. eCollection 2017.


Modeling-Enabled Characterization of Novel NLRX1 Ligands.

Lu P, Hontecillas R, Abedi V, Kale S, Leber A, Heltzel C, Langowski M, Godfrey V, Philipson C, Tubau-Juni N, Carbo A, Girardin S, Uren A, Bassaganya-Riera J.

PLoS One. 2015 Dec 29;10(12):e0145420. doi: 10.1371/journal.pone.0145420. eCollection 2015.


An orphaned Mce-associated membrane protein of Mycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters.

Perkowski EF, Miller BK, McCann JR, Sullivan JT, Malik S, Allen IC, Godfrey V, Hayden JD, Braunstein M.

Mol Microbiol. 2016 Apr;100(1):90-107. doi: 10.1111/mmi.13303. Epub 2016 Feb 5.


A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner.

Donohoe DR, Holley D, Collins LB, Montgomery SA, Whitmore AC, Hillhouse A, Curry KP, Renner SW, Greenwalt A, Ryan EP, Godfrey V, Heise MT, Threadgill DS, Han A, Swenberg JA, Threadgill DW, Bultman SJ.

Cancer Discov. 2014 Dec;4(12):1387-97. doi: 10.1158/2159-8290.CD-14-0501. Epub 2014 Sep 29.


The Collaborative Cross as a resource for modeling human disease: CC011/Unc, a new mouse model for spontaneous colitis.

Rogala AR, Morgan AP, Christensen AM, Gooch TJ, Bell TA, Miller DR, Godfrey VL, de Villena FP.

Mamm Genome. 2014 Apr;25(3-4):95-108. doi: 10.1007/s00335-013-9499-2. Epub 2014 Feb 1.


The BRG1 chromatin remodeler regulates widespread changes in gene expression and cell proliferation during B cell activation.

Holley DW, Groh BS, Wozniak G, Donohoe DR, Sun W, Godfrey V, Bultman SJ.

J Cell Physiol. 2014 Jan;229(1):44-52. doi: 10.1002/jcp.24414.


Understanding precision nitrogen stress to optimize the growth and lipid content tradeoff in oleaginous green microalgae.

Adams C, Godfrey V, Wahlen B, Seefeldt L, Bugbee B.

Bioresour Technol. 2013 Mar;131:188-94. doi: 10.1016/j.biortech.2012.12.143. Epub 2012 Dec 29.


Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart.

Willis MS, Homeister JW, Rosson GB, Annayev Y, Holley D, Holly SP, Madden VJ, Godfrey V, Parise LV, Bultman SJ.

Circ Res. 2012 Aug 17;111(5):e111-22. doi: 10.1161/CIRCRESAHA.112.265587. Epub 2012 Jun 27.


B-type natriuretic peptide is an independent predictor of endothelial function in man.

Pauriah M, Khan F, Lim TK, Elder DH, Godfrey V, Kennedy G, Belch JJ, Booth NA, Struthers AD, Lang CC.

Clin Sci (Lond). 2012 Sep;123(5):307-12. doi: 10.1042/CS20110168.


The BRG1 chromatin remodeler protects against ovarian cysts, uterine tumors, and mammary tumors in a lineage-specific manner.

Serber DW, Rogala A, Makarem M, Rosson GB, Simin K, Godfrey V, Van Dyke T, Eaves CJ, Bultman SJ.

PLoS One. 2012;7(2):e31346. doi: 10.1371/journal.pone.0031346. Epub 2012 Feb 21.


Effects of aldosterone and related steroids on LPS-induced increased expression of inducible NOS in rat aortic smooth muscle cells.

Godfrey V, Martin AL, Struthers AD, Lyles GA.

Br J Pharmacol. 2011 Dec;164(8):2003-14. doi: 10.1111/j.1476-5381.2011.01523.x.


Global array-based transcriptomics from minimal input RNA utilising an optimal RNA isolation process combined with SPIA cDNA probes.

Kennedy L, Pauriah M, Godfrey V, Howie J, Dennis H, Crowther D, Struthers A, Goddard C, Feuerstein G, Lang C, Miele G.

PLoS One. 2011 Mar 22;6(3):e17625. doi: 10.1371/journal.pone.0017625.


Polymorphisms of the angiotensin converting enzyme gene in relation to intrauterine growth restriction.

Uma R, Forsyth JS, Struthers AD, Fraser CG, Godfrey V, Murphy DJ.

Acta Obstet Gynecol Scand. 2010 Sep;89(9):1197-201. doi: 10.3109/00016349.2010.491116.


Polymorphisms of the angiotensin converting enzyme gene in early-onset and late-onset pre-eclampsia.

Uma R, Forsyth SJ, Struthers AD, Fraser CG, Godfrey V, Murphy DJ.

J Matern Fetal Neonatal Med. 2010 Aug;23(8):874-9. doi: 10.3109/14767050903456667.


Metastatic uterine adenocarcinoma in an 8-year-old gilt.

Cannon CZ, Godfrey VL, King-Herbert A, Nielsen JN.

J Am Assoc Lab Anim Sci. 2009 Nov;48(6):795-800.


Inactivation of SNF5 cooperates with p53 loss to accelerate tumor formation in Snf5(+/-);p53(+/-) mice.

DelBove J, Kuwahara Y, Mora-Blanco EL, Godfrey V, Funkhouser WK, Fletcher CD, Van Dyke T, Roberts CW, Weissman BE.

Mol Carcinog. 2009 Dec;48(12):1139-48. doi: 10.1002/mc.20568.


Insulin resistance is highly prevalent and is associated with reduced exercise tolerance in nondiabetic patients with heart failure.

AlZadjali MA, Godfrey V, Khan F, Choy A, Doney AS, Wong AK, Petrie JR, Struthers AD, Lang CC.

J Am Coll Cardiol. 2009 Mar 3;53(9):747-53. doi: 10.1016/j.jacc.2008.08.081.


Effects of cage size and enrichment on reproductive performance and behavior in C57BL/6Tac mice.

Whitaker J, Moy SS, Godfrey V, Nielsen J, Bellinger D, Bradfield J.

Lab Anim (NY). 2009 Jan;38(1):24-34. doi: 10.1038/laban0109-24.


Correlation of angiotensin converting enzyme activity and the genotypes of the I/D polymorphism in the ACE gene with preterm birth and birth weight.

Uma R, Forsyth JS, Struthers AD, Fraser CG, Godfrey V, Murphy DJ.

Eur J Obstet Gynecol Reprod Biol. 2008 Nov;141(1):27-30. doi: 10.1016/j.ejogrb.2008.07.006. Epub 2008 Aug 28.


Biodegradation of Inion fast-absorbing biodegradable plates and screws.

Losken HW, van Aalst JA, Mooney MP, Godfrey VL, Burt T, Teotia S, Dean SB, Moss JR, Rahbar R.

J Craniofac Surg. 2008 May;19(3):748-56. doi: 10.1097/SCS.0b013e31816aab24.


Overexpression of Eg5 causes genomic instability and tumor formation in mice.

Castillo A, Morse HC 3rd, Godfrey VL, Naeem R, Justice MJ.

Cancer Res. 2007 Nov 1;67(21):10138-47.


The effect of cage size on reproductive performance and behavior of C57BL/6 mice.

Whitaker J, Moy SS, Saville BR, Godfrey V, Nielsen J, Bellinger D, Bradfield J.

Lab Anim (NY). 2007 Nov;36(10):32-9.


Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation.

Itahana K, Mao H, Jin A, Itahana Y, Clegg HV, Lindström MS, Bhat KP, Godfrey VL, Evan GI, Zhang Y.

Cancer Cell. 2007 Oct;12(4):355-66.


The functional consequence of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in young healthy volunteers.

Godfrey V, Chan SL, Cassidy A, Butler R, Choy A, Fardon T, Struthers A, Lang C.

Cardiovasc Drug Rev. 2007 Fall;25(3):280-8.


Characterization of mammary tumors from Brg1 heterozygous mice.

Bultman SJ, Herschkowitz JI, Godfrey V, Gebuhr TC, Yaniv M, Perou CM, Magnuson T.

Oncogene. 2008 Jan 17;27(4):460-8. Epub 2007 Jul 16.


FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene.

Zuo T, Wang L, Morrison C, Chang X, Zhang H, Li W, Liu Y, Wang Y, Liu X, Chan MW, Liu JQ, Love R, Liu CG, Godfrey V, Shen R, Huang TH, Yang T, Park BK, Wang CY, Zheng P, Liu Y.

Cell. 2007 Jun 29;129(7):1275-86. Epub 2007 Jun 14. Erratum in: Cell. 2008 Aug 8;134(3):546.


Tumor-specific cooperation of retinoblastoma protein family and Snf5 inactivation.

Chai J, Lu X, Godfrey V, Fletcher C, Roberts CW, Van Dyke T, Weissman BE.

Cancer Res. 2007 Apr 1;67(7):3002-9.


Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice.

Cressman VL, Backlund DC, Avrutskaya AV, Leadon SA, Godfrey V, Koller BH.

Mol Cell Biol. 2006 Dec;26(24):9571. No abstract available.


Evaluation of dosing regimen of respirable rifampicin biodegradable microspheres in the treatment of tuberculosis in the guinea pig.

Garcia-Contreras L, Sethuraman V, Kazantseva M, Godfrey V, Hickey AJ.

J Antimicrob Chemother. 2006 Nov;58(5):980-6. Epub 2006 Sep 13.


Foxp3 controls autoreactive T cell activation through transcriptional regulation of early growth response genes and E3 ubiquitin ligase genes, independently of thymic selection.

Chang X, Chen L, Wen J, Godfrey VL, Qiao G, Hussien Y, Zhang J, Gao JX.

Clin Immunol. 2006 Dec;121(3):274-85. Epub 2006 Aug 30.


Effect of spironolactone on C-reactive protein levels in patients with heart disease.

Godfrey V, Farquharson CA, Macdonald JE, Yee KM, Struthers AD.

Int J Cardiol. 2007 Apr 25;117(2):282-4. Epub 2006 Aug 8.


The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis.

Chang X, Gao JX, Jiang Q, Wen J, Seifers N, Su L, Godfrey VL, Zuo T, Zheng P, Liu Y.

J Exp Med. 2005 Oct 17;202(8):1141-51.


Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: effects of dose, route, and diet.

Bissahoyo A, Pearsall RS, Hanlon K, Amann V, Hicks D, Godfrey VL, Threadgill DW.

Toxicol Sci. 2005 Dec;88(2):340-5. Epub 2005 Sep 8.


Neutrophil dysfunction in guanosine 3',5'-cyclic monophosphate-dependent protein kinase I-deficient mice.

Werner CG, Godfrey V, Arnold RR, Featherstone GL, Bender D, Schlossmann J, Schiemann M, Hofmann F, Pryzwansky KB.

J Immunol. 2005 Aug 1;175(3):1919-29.


Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage.

Lee D, Pearsall RS, Das S, Dey SK, Godfrey VL, Threadgill DW.

Mol Cell Biol. 2004 Oct;24(20):8907-16.


The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development.

Gebuhr TC, Kovalev GI, Bultman S, Godfrey V, Su L, Magnuson T.

J Exp Med. 2003 Dec 15;198(12):1937-49.


CHIP activates HSF1 and confers protection against apoptosis and cellular stress.

Dai Q, Zhang C, Wu Y, McDonough H, Whaley RA, Godfrey V, Li HH, Madamanchi N, Xu W, Neckers L, Cyr D, Patterson C.

EMBO J. 2003 Oct 15;22(20):5446-58.


Pathology of mouse models of intestinal cancer: consensus report and recommendations.

Boivin GP, Washington K, Yang K, Ward JM, Pretlow TP, Russell R, Besselsen DG, Godfrey VL, Doetschman T, Dove WF, Pitot HC, Halberg RB, Itzkowitz SH, Groden J, Coffey RJ.

Gastroenterology. 2003 Mar;124(3):762-77. Review. No abstract available.


Haploinsufficiency of p18(INK4c) sensitizes mice to carcinogen-induced tumorigenesis.

Bai F, Pei XH, Godfrey VL, Xiong Y.

Mol Cell Biol. 2003 Feb;23(4):1269-77.


Airway surface liquid recovered by lavage with perfluorocarbon liquid in cats.

Southern KW, Funkhouser WK, Kazachkova I, Godfrey VL, Fordham LA, Gatzy JT, Barker PM.

Eur J Clin Invest. 2002 Dec;32(12):956-61.


Impact of ionizing radiation and genetic background on mammary tumorigenesis in p53-deficient mice.

Backlund MG, Trasti SL, Backlund DC, Cressman VL, Godfrey V, Koller BH.

Cancer Res. 2001 Sep 1;61(17):6577-82.


Gene expression and cytokine and enzyme activation in the liver after a burn injury.

Nishiura T, Nishimura T, deSerres S, Godfrey V, Bradham CA, Nakagawa T, Brenner DA, Meyer AA.

J Burn Care Rehabil. 2000 Mar-Apr;21(2):135-41.


Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti.

Makris C, Godfrey VL, Krähn-Senftleben G, Takahashi T, Roberts JL, Schwarz T, Feng L, Johnson RS, Karin M.

Mol Cell. 2000 Jun;5(6):969-79.


Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice.

Cressman VL, Backlund DC, Avrutskaya AV, Leadon SA, Godfrey V, Koller BH.

Mol Cell Biol. 1999 Oct;19(10):7061-75. Erratum in: Mol Cell Biol. 2006 Dec;26(24):9571.


Errors associated with determining the susceptibilities of staphylococci to trimethoprim by the Vitek GPS-AK card.

Carmichael IC, Godfrey V, Nicholson G.

J Antimicrob Chemother. 1999 Aug;44(2):293-4. No abstract available.


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