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Items: 17

1.

CD160 Stimulates CD8+ T Cell Responses and Is Required for Optimal Protective Immunity to Listeria monocytogenes.

Tan CL, Peluso MJ, Drijvers JM, Mera CM, Grande SM, Brown KE, Godec J, Freeman GJ, Sharpe AH.

Immunohorizons. 2018 Aug 27;2(7):238-250. doi: 10.4049/immunohorizons.1800039.

PMID:
31022694
2.

Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state.

Afik S, Yates KB, Bi K, Darko S, Godec J, Gerdemann U, Swadling L, Douek DC, Klenerman P, Barnes EJ, Sharpe AH, Haining WN, Yosef N.

Nucleic Acids Res. 2017 Sep 19;45(16):e148. doi: 10.1093/nar/gkx615.

3.

Erratum: The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection.

Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW.

Nat Immunol. 2017 Sep 19;18(10):1173. doi: 10.1038/ni1017-1173d. No abstract available.

PMID:
28926530
4.

The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection.

Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW.

Nat Immunol. 2017 Jul;18(7):791-799. doi: 10.1038/ni.3755. Epub 2017 May 22. Erratum in: Nat Immunol. 2017 Sep 19;18(10 ):1173.

5.

The epigenetic landscape of T cell exhaustion.

Sen DR, Kaminski J, Barnitz RA, Kurachi M, Gerdemann U, Yates KB, Tsao HW, Godec J, LaFleur MW, Brown FD, Tonnerre P, Chung RT, Tully DC, Allen TM, Frahm N, Lauer GM, Wherry EJ, Yosef N, Haining WN.

Science. 2016 Dec 2;354(6316):1165-1169. Epub 2016 Oct 27.

6.

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.

Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen DR, Kurachi M, Barnitz RA, Bartman C, Bengsch B, Huang AC, Schenkel JM, Vahedi G, Haining WN, Berger SL, Wherry EJ.

Science. 2016 Dec 2;354(6316):1160-1165. Epub 2016 Oct 27.

7.

Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling.

Dobbins J, Gagnon E, Godec J, Pyrdol J, Vignali DA, Sharpe AH, Wucherpfennig KW.

Sci Signal. 2016 Jul 26;9(438):ra75. doi: 10.1126/scisignal.aaf0626.

8.

Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation.

Godec J, Tan Y, Liberzon A, Tamayo P, Bhattacharya S, Butte AJ, Mesirov JP, Haining WN.

Immunity. 2016 Jan 19;44(1):194-206. doi: 10.1016/j.immuni.2015.12.006. Epub 2016 Jan 12.

9.

CD39 Expression Identifies Terminally Exhausted CD8+ T Cells.

Gupta PK, Godec J, Wolski D, Adland E, Yates K, Pauken KE, Cosgrove C, Ledderose C, Junger WG, Robson SC, Wherry EJ, Alter G, Goulder PJ, Klenerman P, Sharpe AH, Lauer GM, Haining WN.

PLoS Pathog. 2015 Oct 20;11(10):e1005177. doi: 10.1371/journal.ppat.1005177. eCollection 2015 Oct.

10.

Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans.

Ruparelia N, Godec J, Lee R, Chai JT, Dall'Armellina E, McAndrew D, Digby JE, Forfar JC, Prendergast BD, Kharbanda RK, Banning AP, Neubauer S, Lygate CA, Channon KM, Haining NW, Choudhury RP.

Eur Heart J. 2015 Aug 1;36(29):1923-34. doi: 10.1093/eurheartj/ehv195. Epub 2015 May 16.

11.

Keys to the kingdom.

Wong SC, Sasportas LS, Richardson K, Gordon BR, Jayatunga MK, Shalizi A, Pfister SX, Stanzl EG, Chui C, Mathur M, Thomsen SK, Shetty C, Pliuskys L, Mehra A, Bahar H, Godec J, Jong S, Perez DA.

Nat Biotechnol. 2015 Mar;33(3):232-6. doi: 10.1038/nbt.3159. Epub 2015 Feb 26. No abstract available.

PMID:
25748908
12.

Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation.

Godec J, Cowley GS, Barnitz RA, Alkan O, Root DE, Sharpe AH, Haining WN.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):512-7. doi: 10.1073/pnas.1413291112. Epub 2014 Dec 29. Erratum in: Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4968. Alkan, Ozan [added].

13.

Circulating T follicular regulatory and helper cells have memory-like properties.

Sage PT, Alvarez D, Godec J, von Andrian UH, Sharpe AH.

J Clin Invest. 2014 Dec;124(12):5191-204. doi: 10.1172/JCI76861. Epub 2014 Oct 27.

14.

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells.

Kurachi M, Barnitz RA, Yosef N, Odorizzi PM, DiIorio MA, Lemieux ME, Yates K, Godec J, Klatt MG, Regev A, Wherry EJ, Haining WN.

Nat Immunol. 2014 Apr;15(4):373-83. doi: 10.1038/ni.2834. Epub 2014 Mar 2.

15.

The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells.

Wang Y, Godec J, Ben-Aissa K, Cui K, Zhao K, Pucsek AB, Lee YK, Weaver CT, Yagi R, Lazarevic V.

Immunity. 2014 Mar 20;40(3):355-66. doi: 10.1016/j.immuni.2014.01.002. Epub 2014 Feb 13.

16.

MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma.

Grayson AR, Walsh EM, Cameron MJ, Godec J, Ashworth T, Ambrose JM, Aserlind AB, Wang H, Evan G, Kluk MJ, Bradner JE, Aster JC, French CA.

Oncogene. 2014 Mar 27;33(13):1736-1742. doi: 10.1038/onc.2013.126. Epub 2013 Apr 22.

17.

TLR signaling is required for Salmonella typhimurium virulence.

Arpaia N, Godec J, Lau L, Sivick KE, McLaughlin LM, Jones MB, Dracheva T, Peterson SN, Monack DM, Barton GM.

Cell. 2011 Mar 4;144(5):675-88. doi: 10.1016/j.cell.2011.01.031.

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