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Recombinant Membrane Protein Methods.

Bill RM, Goddard AD, Rothnie AJ.

Methods. 2018 Sep 1;147:1-2. doi: 10.1016/j.ymeth.2018.08.007. No abstract available.


Single molecule fluorescence for membrane proteins.

Castell OK, Dijkman PM, Wiseman DN, Goddard AD.

Methods. 2018 Sep 1;147:221-228. doi: 10.1016/j.ymeth.2018.05.024. Epub 2018 May 30. Review.


Validation of the 16-Gene Recurrence Score in Patients with Locoregional, High-Risk Renal Cell Carcinoma from a Phase III Trial of Adjuvant Sunitinib.

Rini BI, Escudier B, Martini JF, Magheli A, Svedman C, Lopatin M, Knezevic D, Goddard AD, Febbo PG, Li R, Lin X, Valota O, Staehler M, Motzer RJ, Ravaud A.

Clin Cancer Res. 2018 Sep 15;24(18):4407-4415. doi: 10.1158/1078-0432.CCR-18-0323. Epub 2018 May 17.


Mechanistic and phenotypic studies of bicarinalin, BP100 and colistin action on Acinetobacter baumannii.

Eales MG, Ferrari E, Goddard AD, Lancaster L, Sanderson P, Miller C.

Res Microbiol. 2018 Jul - Aug;169(6):296-302. doi: 10.1016/j.resmic.2018.04.005. Epub 2018 May 8.


Dynamic tuneable G protein-coupled receptor monomer-dimer populations.

Dijkman PM, Castell OK, Goddard AD, Munoz-Garcia JC, de Graaf C, Wallace MI, Watts A.

Nat Commun. 2018 Apr 27;9(1):1710. doi: 10.1038/s41467-018-03727-6.


Self-Sampling for Human Papillomavirus Testing: Increased Cervical Cancer Screening Participation and Incorporation in International Screening Programs.

Gupta S, Palmer C, Bik EM, Cardenas JP, Nuñez H, Kraal L, Bird SW, Bowers J, Smith A, Walton NA, Goddard AD, Almonacid DE, Zneimer S, Richman J, Apte ZS.

Front Public Health. 2018 Apr 9;6:77. doi: 10.3389/fpubh.2018.00077. eCollection 2018. Review.


Microbial biotransformations in the human distal gut.

Bik EM, Ugalde JA, Cousins J, Goddard AD, Richman J, Apte ZS.

Br J Pharmacol. 2017 Nov 8. doi: 10.1111/bph.14085. [Epub ahead of print] Review.


Neurotensin receptor 1 facilitates intracellular and transepithelial delivery of macromolecules.

Bird JL, Simpson R, Vllasaliu D, Goddard AD.

Eur J Pharm Biopharm. 2017 Oct;119:300-309. doi: 10.1016/j.ejpb.2017.06.027. Epub 2017 Jul 6.


16S rRNA gene sequencing and healthy reference ranges for 28 clinically relevant microbial taxa from the human gut microbiome.

Almonacid DE, Kraal L, Ossandon FJ, Budovskaya YV, Cardenas JP, Bik EM, Goddard AD, Richman J, Apte ZS.

PLoS One. 2017 May 3;12(5):e0176555. doi: 10.1371/journal.pone.0176555. eCollection 2017.


The Paracoccus denitrificans NarK-like nitrate and nitrite transporters-probing nitrate uptake and nitrate/nitrite exchange mechanisms.

Goddard AD, Bali S, Mavridou DA, Luque-Almagro VM, Gates AJ, Dolores Roldán M, Newstead S, Richardson DJ, Ferguson SJ.

Mol Microbiol. 2017 Jan;103(1):117-133. doi: 10.1111/mmi.13546. Epub 2016 Oct 27.


Reconstitution of membrane proteins: a GPCR as an example.

Goddard AD, Dijkman PM, Adamson RJ, dos Reis RI, Watts A.

Methods Enzymol. 2015;556:405-24. doi: 10.1016/bs.mie.2015.01.004. Epub 2015 Mar 20.


Estimating the time at which commercial broiler flocks in Great Britain become infected with Campylobacter: a Bayesian approach.

Goddard AD, Arnold ME, Allen VM, Snary EL.

Epidemiol Infect. 2014 Sep;142(9):1884-92. doi: 10.1017/S0950268813002926. Epub 2013 Nov 20.


Lipid-dependent GPCR dimerization.

Goddard AD, Dijkman PM, Adamson RJ, Watts A.

Methods Cell Biol. 2013;117:341-57. doi: 10.1016/B978-0-12-408143-7.00018-9.


Analytical validation of the Oncotype DX prostate cancer assay - a clinical RT-PCR assay optimized for prostate needle biopsies.

Knezevic D, Goddard AD, Natraj N, Cherbavaz DB, Clark-Langone KM, Snable J, Watson D, Falzarano SM, Magi-Galluzzi C, Klein EA, Quale C.

BMC Genomics. 2013 Oct 8;14:690. doi: 10.1186/1471-2164-14-690.


Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists.

Basu S, Leonard JC, Desai N, Mavridou DA, Tang KH, Goddard AD, Ginger ML, Lukeš J, Allen JW.

Eukaryot Cell. 2013 Feb;12(2):343-55. doi: 10.1128/EC.00304-12. Epub 2012 Dec 21.


Contributions of fluorescence techniques to understanding G protein-coupled receptor dimerisation.

Goddard AD, Watts A.

Biophys Rev. 2012 Dec;4(4):291-298. doi: 10.1007/s12551-012-0073-z. Epub 2012 Apr 12. Review.


A quantitative release assessment for the noncommercial movement of companion animals: risk of rabies reintroduction to the United kingdom.

Goddard AD, Donaldson NM, Horton DL, Kosmider R, Kelly LA, Sayers AR, Breed AC, Freuling CM, Müller T, Shaw SE, Hallgren G, Fooks AR, Snary EL.

Risk Anal. 2012 Oct;32(10):1769-83. doi: 10.1111/j.1539-6924.2012.01804.x. Epub 2012 Apr 4.


Regulation of G protein-coupled receptors by palmitoylation and cholesterol.

Goddard AD, Watts A.

BMC Biol. 2012 Mar 19;10:27. doi: 10.1186/1741-7007-10-27.


Cytochrome c biogenesis System I.

Stevens JM, Mavridou DA, Hamer R, Kritsiligkou P, Goddard AD, Ferguson SJ.

FEBS J. 2011 Nov;278(22):4170-8. doi: 10.1111/j.1742-4658.2011.08376.x. Epub 2011 Oct 20. Review.


Oxidation state-dependent protein-protein interactions in disulfide cascades.

Mavridou DA, Saridakis E, Kritsiligkou P, Goddard AD, Stevens JM, Ferguson SJ, Redfield C.

J Biol Chem. 2011 Jul 15;286(28):24943-56. doi: 10.1074/jbc.M111.236141. Epub 2011 May 3.


A composite biochemical system for bacterial nitrate and nitrite assimilation as exemplified by Paracoccus denitrificans.

Gates AJ, Luque-Almagro VM, Goddard AD, Ferguson SJ, Roldán MD, Richardson DJ.

Biochem J. 2011 May 1;435(3):743-53. doi: 10.1042/BJ20101920.


DNA-templated protein arrays for single-molecule imaging.

Selmi DN, Adamson RJ, Attrill H, Goddard AD, Gilbert RJ, Watts A, Turberfield AJ.

Nano Lett. 2011 Feb 9;11(2):657-60. doi: 10.1021/nl1037769. Epub 2011 Jan 10.


Solution- and solid-state NMR studies of GPCRs and their ligands.

Tapaneeyakorn S, Goddard AD, Oates J, Willis CL, Watts A.

Biochim Biophys Acta. 2011 Jun;1808(6):1462-75. doi: 10.1016/j.bbamem.2010.10.003. Epub 2010 Oct 15. Review.


c-Type cytochrome biogenesis can occur via a natural Ccm system lacking CcmH, CcmG, and the heme-binding histidine of CcmE.

Goddard AD, Stevens JM, Rao F, Mavridou DA, Chan W, Richardson DJ, Allen JW, Ferguson SJ.

J Biol Chem. 2010 Jul 23;285(30):22882-9. doi: 10.1074/jbc.M110.133421. Epub 2010 May 13. Erratum in: J Biol Chem. 2011 Aug 19;286(33):29442.


Comparing the substrate specificities of cytochrome c biogenesis Systems I and II: bioenergetics.

Goddard AD, Stevens JM, Rondelet A, Nomerotskaia E, Allen JW, Ferguson SJ.

FEBS J. 2010 Feb;277(3):726-37. doi: 10.1111/j.1742-4658.2009.07517.x. Epub 2009 Dec 29.


Control of periplasmic interdomain thiol:disulfide exchange in the transmembrane oxidoreductase DsbD.

Mavridou DA, Stevens JM, Goddard AD, Willis AC, Ferguson SJ, Redfield C.

J Biol Chem. 2009 Jan 30;284(5):3219-26. doi: 10.1074/jbc.M805963200. Epub 2008 Nov 12.


Interdependence of two NarK domains in a fused nitrate/nitrite transporter.

Goddard AD, Moir JW, Richardson DJ, Ferguson SJ.

Mol Microbiol. 2008 Nov;70(3):667-81. doi: 10.1111/j.1365-2958.2008.06436.x. Epub 2008 Sep 18.


Predicting clinical benefit in non-small-cell lung cancer patients treated with epidermal growth factor tyrosine kinase inhibitors.

Amler LC, Goddard AD, Hillan KJ.

Cold Spring Harb Symp Quant Biol. 2005;70:483-8. Review.


Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib.

Eberhard DA, Johnson BE, Amler LC, Goddard AD, Heldens SL, Herbst RS, Ince WL, Jänne PA, Januario T, Johnson DH, Klein P, Miller VA, Ostland MA, Ramies DA, Sebisanovic D, Stinson JA, Zhang YR, Seshagiri S, Hillan KJ.

J Clin Oncol. 2005 Sep 1;23(25):5900-9. Epub 2005 Jul 25.


BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue: cloning, organization of the human gene and assessment of a potential link to obesity.

Adams SH, Chui C, Schilbach SL, Yu XX, Goddard AD, Grimaldi JC, Lee J, Dowd P, Colman S, Lewin DA.

Biochem J. 2001 Nov 15;360(Pt 1):135-42.


Is Mycoplasma hominis a vaginal pathogen?

Arya OP, Tong CY, Hart CA, Pratt BC, Hughes S, Roberts P, Kirby P, Howel J, McCormick A, Goddard AD.

Sex Transm Infect. 2001 Feb;77(1):58-62.


IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1.

Lee J, Ho WH, Maruoka M, Corpuz RT, Baldwin DT, Foster JS, Goddard AD, Yansura DG, Vandlen RL, Wood WI, Gurney AL.

J Biol Chem. 2001 Jan 12;276(2):1660-4.


Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.

Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL.

J Biol Chem. 2000 Oct 6;275(40):31335-9.


Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.

Gurney AL, Marsters SA, Huang RM, Pitti RM, Mark DT, Baldwin DT, Gray AM, Dowd AD, Brush AD, Heldens AD, Schow AD, Goddard AD, Wood WI, Baker KP, Godowski PJ, Ashkenazi A.

Curr Biol. 1999 Feb 25;9(4):215-8.


Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer.

Pitti RM, Marsters SA, Lawrence DA, Roy M, Kischkel FC, Dowd P, Huang A, Donahue CJ, Sherwood SW, Baldwin DT, Godowski PJ, Wood WI, Gurney AL, Hillan KJ, Cohen RL, Goddard AD, Botstein D, Ashkenazi A.

Nature. 1998 Dec 17;396(6712):699-703.


WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.

Pennica D, Swanson TA, Welsh JW, Roy MA, Lawrence DA, Lee J, Brush J, Taneyhill LA, Deuel B, Lew M, Watanabe C, Cohen RL, Melhem MF, Finley GG, Quirke P, Goddard AD, Hillan KJ, Gurney AL, Botstein D, Levine AJ.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14717-22.


A novel receptor for Apo2L/TRAIL contains a truncated death domain.

Marsters SA, Sheridan JP, Pitti RM, Huang A, Skubatch M, Baldwin D, Yuan J, Gurney A, Goddard AD, Godowski P, Ashkenazi A.

Curr Biol. 1997 Dec 1;7(12):1003-6.


Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors.

Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, Ramakrishnan L, Gray CL, Baker K, Wood WI, Goddard AD, Godowski P, Ashkenazi A.

Science. 1997 Aug 8;277(5327):818-21.


Partial growth-hormone insensitivity: the role of growth-hormone receptor mutations in idiopathic short stature.

Goddard AD, Dowd P, Chernausek S, Geffner M, Gertner J, Hintz R, Hopwood N, Kaplan S, Plotnick L, Rogol A, Rosenfield R, Saenger P, Mauras N, Hershkopf R, Angulo M, Attie K.

J Pediatr. 1997 Jul;131(1 Pt 2):S51-5.


Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B.

Marsters SA, Sheridan JP, Donahue CJ, Pitti RM, Gray CL, Goddard AD, Bauer KD, Ashkenazi A.

Curr Biol. 1996 Dec 1;6(12):1669-76.


Mutations of the growth hormone receptor in children with idiopathic short stature. The Growth Hormone Insensitivity Study Group.

Goddard AD, Covello R, Luoh SM, Clackson T, Attie KM, Gesundheit N, Rundle AC, Wells JA, Carlsson LM.

N Engl J Med. 1995 Oct 26;333(17):1093-8.


Cloning of the murine homolog of the leukemia-associated PML gene.

Goddard AD, Yuan JQ, Fairbairn L, Dexter M, Borrow J, Kozak C, Solomon E.

Mamm Genome. 1995 Oct;6(10):732-7.


Molecular cloning of a ligand for the EPH-related receptor protein-tyrosine kinase Htk.

Bennett BD, Zeigler FC, Gu Q, Fendly B, Goddard AD, Gillett N, Matthews W.

Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1866-70.


Genetic aspects of cancer.

Goddard AD, Solomon E.

Adv Hum Genet. 1993;21:321-76. Review. No abstract available.


Diagnosis of acute promyelocytic leukaemia by RT-PCR: detection of PML-RARA and RARA-PML fusion transcripts.

Borrow J, Goddard AD, Gibbons B, Katz F, Swirsky D, Fioretos T, Dube I, Winfield DA, Kingston J, Hagemeijer A, et al.

Br J Haematol. 1992 Nov;82(3):529-40.


Mechanisms of loss of heterozygosity in retinoblastoma.

Zhu X, Dunn JM, Goddard AD, Squire JA, Becker A, Phillips RA, Gallie BL.

Cytogenet Cell Genet. 1992;59(4):248-52.


Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia.

Goddard AD, Borrow J, Freemont PS, Solomon E.

Science. 1991 Nov 29;254(5036):1371-4.


Chromosome aberrations and cancer.

Solomon E, Borrow J, Goddard AD.

Science. 1991 Nov 22;254(5035):1153-60. Review.


Construction and regional localization of clones from a NotI linking library from human chromosome 17q.

Borrow J, Black DM, Goddard AD, Yagle MK, Frischauf AM, Solomon E.

Genomics. 1991 Jun;10(2):477-80.


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