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Mechanisms involved in epigenetic down-regulation of Gfap under maternal hypothyroidism.

Kumar P, Godbole NM, Chaturvedi CP, Singh RS, George N, Upadhyay A, Anjum B, Godbole MM, Sinha RA.

Biochem Biophys Res Commun. 2018 Jul 20;502(3):375-381. doi: 10.1016/j.bbrc.2018.05.173.


Erratum. Pathophysiological Mechanism of Bone Loss in Type 2 Diabetes Involves Inverse Regulation of Osteoblast Function by PGC-1α and Skeletal Muscle Atrogenes: AdipoR1 as a Potential Target for Reversing Diabetes-Induced Osteopenia. Diabetes 2015;64:2609-2623.

Khan MP, Singh AK, Joharapurkar AA, Yadav M, Shree S, Kumar H, Gurjar A, Mishra JS, Tiwari MC, Nagar GK, Kumar S, Ramachandran R, Sharan A, Jain MR, Trivedi AK, Maurya R, Godbole MM, Gayen JR, Sanyal S, Chattopadhyay N.

Diabetes. 2017 Dec;66(12):3142-3143. doi: 10.2337/db17-er12b. Epub 2017 Oct 5. No abstract available.


miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells.

Godbole M, Chandrani P, Gardi N, Dhamne H, Patel K, Yadav N, Gupta S, Badwe R, Dutt A.

Cancer Biol Ther. 2017 Oct 3;18(10):801-805. doi: 10.1080/15384047.2017.1373216. Epub 2017 Sep 6.


Progesterone suppresses the invasion and migration of breast cancer cells irrespective of their progesterone receptor status - a short report.

Godbole M, Tiwary K, Badwe R, Gupta S, Dutt A.

Cell Oncol (Dordr). 2017 Aug;40(4):411-417. doi: 10.1007/s13402-017-0330-z. Epub 2017 Jun 26.


Inhibition of Intracellular Type 10 Adenylyl Cyclase Protects Cortical Neurons Against Reperfusion-Induced Mitochondrial Injury and Apoptosis.

Chagtoo M, George N, Pathak N, Tiwari S, Godbole MM, Ladilov Y.

Mol Neurobiol. 2018 Mar;55(3):2471-2482. doi: 10.1007/s12035-017-0473-y. Epub 2017 Apr 6.


hsa-miR-4485 regulates mitochondrial functions and inhibits the tumorigenicity of breast cancer cells.

Sripada L, Singh K, Lipatova AV, Singh A, Prajapati P, Tomar D, Bhatelia K, Roy M, Singh R, Godbole MM, Chumakov PM, Singh R.

J Mol Med (Berl). 2017 Jun;95(6):641-651. doi: 10.1007/s00109-017-1517-5. Epub 2017 Feb 20.


Inhibition of Inositol 1, 4, 5-Trisphosphate Receptor Induce Breast Cancer Cell Death Through Deregulated Autophagy and Cellular Bioenergetics.

Singh A, Chagtoo M, Tiwari S, George N, Chakravarti B, Khan S, Lakshmi S, Godbole MM.

J Cell Biochem. 2017 Aug;118(8):2333-2346. doi: 10.1002/jcb.25891. Epub 2017 Apr 25.


1H NMR Metabolomics Reveals Association of High Expression of Inositol 1, 4, 5 Trisphosphate Receptor and Metabolites in Breast Cancer Patients.

Singh A, Sharma RK, Chagtoo M, Agarwal G, George N, Sinha N, Godbole MM.

PLoS One. 2017 Jan 10;12(1):e0169330. doi: 10.1371/journal.pone.0169330. eCollection 2017.


Greater efficacy of atorvastatin versus a non-statin lipid-lowering agent against renal injury: potential role as a histone deacetylase inhibitor.

Singh RS, Chaudhary DK, Mohan A, Kumar P, Chaturvedi CP, Ecelbarger CM, Godbole MM, Tiwari S.

Sci Rep. 2016 Nov 30;6:38034. doi: 10.1038/srep38034.


Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer.

Upadhyay P, Nair S, Kaur E, Aich J, Dani P, Sethunath V, Gardi N, Chandrani P, Godbole M, Sonawane K, Prasad R, Kannan S, Agarwal B, Kane S, Gupta S, Dutt S, Dutt A.

Oncotarget. 2016 Aug 2;7(31):50437-50449. doi: 10.18632/oncotarget.10419.


Zoledronate and Molecular Iodine Cause Synergistic Cell Death in Triple Negative Breast Cancer through Endoplasmic Reticulum Stress.

Tripathi R, Singh P, Singh A, Chagtoo M, Khan S, Tiwari S, Agarwal G, Meeran SM, Godbole MM.

Nutr Cancer. 2016 May-Jun;68(4):679-88. doi: 10.1080/01635581.2016.1158293. Epub 2016 Apr 26.


Theophylline, a methylxanthine drug induces osteopenia and alters calciotropic hormones, and prophylactic vitamin D treatment protects against these changes in rats.

Pal S, Khan K, China SP, Mittal M, Porwal K, Shrivastava R, Taneja I, Hossain Z, Mandalapu D, Gayen JR, Wahajuddin M, Sharma VL, Trivedi AK, Sanyal S, Bhadauria S, Godbole MM, Gupta SK, Chattopadhyay N.

Toxicol Appl Pharmacol. 2016 Mar 15;295:12-25. doi: 10.1016/j.taap.2016.02.002. Epub 2016 Feb 3.


Systematic Review: Interventions to Educate Children About Dog Safety and Prevent Pediatric Dog-Bite Injuries: A Meta-Analytic Review.

Shen J, Rouse J, Godbole M, Wells HL, Boppana S, Schwebel DC.

J Pediatr Psychol. 2017 Aug 1;42(7):779-791. doi: 10.1093/jpepsy/jsv164. Review.


Histone deacetylase inhibition reduces hypothyroidism-induced neurodevelopmental defects in rats.

Kumar P, Mohan V, Sinha RA, Chagtoo M, Godbole MM.

J Endocrinol. 2015 Nov;227(2):83-92. doi: 10.1530/JOE-15-0168.


Pathophysiological Mechanism of Bone Loss in Type 2 Diabetes Involves Inverse Regulation of Osteoblast Function by PGC-1α and Skeletal Muscle Atrogenes: AdipoR1 as a Potential Target for Reversing Diabetes-Induced Osteopenia.

Khan MP, Singh AK, Joharapurkar AA, Yadav M, Shree S, Kumar H, Gurjar A, Mishra JS, Tiwari MC, Nagar GK, Kumar S, Ramachandran R, Sharan A, Jain MR, Trivedi AK, Maurya R, Godbole MM, Gayen JR, Sanyal S, Chattopadhyay N.

Diabetes. 2015 Jul;64(7):2609-23. doi: 10.2337/db14-1611. Epub 2015 Jan 29. Erratum in: Diabetes. 2017 Dec;66(12 ):3142-3143.


CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons: Rapid way to detect EGFR and KRAS mutations.

Ramteke MP, Patel KJ, Godbole M, Vyas M, Karve K, Choughule A, Prabhash K, Dutt A.

Version 2. F1000Res. 2015 Jun 23 [revised 2016 Jan 1];4:160. doi: 10.12688/f1000research.6663.2. eCollection 2015.


Phytochemicals for breast cancer therapy: current status and future implications.

Siddiqui JA, Singh A, Chagtoo M, Singh N, Godbole MM, Chakravarti B.

Curr Cancer Drug Targets. 2015;15(2):116-35. Review.


Insulin regulates nitric oxide production in the kidney collecting duct cells.

Pandey G, Makhija E, George N, Chakravarti B, Godbole MM, Ecelbarger CM, Tiwari S.

J Biol Chem. 2015 Feb 27;290(9):5582-91. doi: 10.1074/jbc.M114.592741. Epub 2014 Dec 22.


Thioaryl naphthylmethanone oxime ether analogs as novel anticancer agents.

Chakravarti B, Akhtar T, Rai B, Yadav M, Akhtar Siddiqui J, Dhar Dwivedi SK, Thakur R, Singh AK, Singh AK, Kumar H, Khan K, Pal S, Rath SK, Lal J, Konwar R, Trivedi AK, Datta D, Mishra DP, Godbole MM, Sanyal S, Chattopadhyay N, Kumar A.

J Med Chem. 2014 Oct 9;57(19):8010-25. doi: 10.1021/jm500873e. Epub 2014 Sep 22.


Orally active osteoanabolic agent GTDF binds to adiponectin receptors, with a preference for AdipoR1, induces adiponectin-associated signaling, and improves metabolic health in a rodent model of diabetes.

Singh AK, Joharapurkar AA, Khan MP, Mishra JS, Singh N, Yadav M, Hossain Z, Khan K, Kumar S, Dhanesha NA, Mishra DP, Maurya R, Sharma S, Jain MR, Trivedi AK, Godbole MM, Gayen JR, Chattopadhyay N, Sanyal S.

Diabetes. 2014 Oct;63(10):3530-44. doi: 10.2337/db13-1619. Epub 2014 May 21.


Vitamin D and insulin resistance in postmenopausal Indian women.

Agarwal N, Mithal A, Kaur P, Dhingra V, Godbole MM, Shukla M.

Indian J Endocrinol Metab. 2014 Jan;18(1):89-93. doi: 10.4103/2230-8210.126583.


QSAR guided semi-synthesis and in-vitro validation of anticancer activity in ursolic acid derivatives.

Kalani K, Yadav DK, Singh A, Khan F, Godbole MM, Srivastava SK.

Curr Top Med Chem. 2014;14(8):1005-13.


Curcumin conjugates induce apoptosis via a mitochondrion dependent pathway in MCF-7 and MDA-MB-231 cell lines.

Singh DV, Agarwal S, Singh P, Godbole MM, Misra K.

Asian Pac J Cancer Prev. 2013;14(10):5797-804.


Antiviral signaling protein MITA acts as a tumor suppressor in breast cancer by regulating NF-κB induced cell death.

Bhatelia K, Singh A, Tomar D, Singh K, Sripada L, Chagtoo M, Prajapati P, Singh R, Godbole MM, Singh R.

Biochim Biophys Acta. 2014 Feb;1842(2):144-53. doi: 10.1016/j.bbadis.2013.11.006. Epub 2013 Nov 13.


Effect of two different doses of oral cholecalciferol supplementation on serum 25-hydroxy-vitamin D levels in healthy Indian postmenopausal women: A randomized controlled trial.

Agarwal N, Mithal A, Dhingra V, Kaur P, Godbole MM, Shukla M.

Indian J Endocrinol Metab. 2013 Sep;17(5):883-9. doi: 10.4103/2230-8210.117237.


Report on institutions rankings - Where our medical institutions stand? Our big neighbour & the way forward.

Godbole MM, Misra R, Pandey CM, Srivastava S.

Indian J Med Res. 2013 Jun;137(6):1204-6. No abstract available.


Deletion of the insulin receptor in the proximal tubule promotes hyperglycemia.

Tiwari S, Singh RS, Li L, Tsukerman S, Godbole M, Pandey G, Ecelbarger CM.

J Am Soc Nephrol. 2013 Jul;24(8):1209-14. doi: 10.1681/ASN.2012060628. Epub 2013 May 30.


Wilm's tumor-1 protein levels in urinary exosomes from diabetic patients with or without proteinuria.

Kalani A, Mohan A, Godbole MM, Bhatia E, Gupta A, Sharma RK, Tiwari S.

PLoS One. 2013;8(3):e60177. doi: 10.1371/journal.pone.0060177. Epub 2013 Mar 27.


Iodine plus n-3 fatty acid supplementation augments rescue of postnatal neuronal abnormalities in iodine-deficient rat cerebellum.

Pal A, Mohan V, Modi DR, Sinha RA, Rastogi L, Kumar P, Godbole MM.

Br J Nutr. 2013 Aug;110(4):659-70. doi: 10.1017/S0007114512005569. Epub 2013 Jan 14.


Prevalence of vitamin D deficiency in critically ill patients and its influence on outcome: experience from a tertiary care centre in North India (an observational study).

Azim A, Ahmed A, Yadav S, Baronia AK, Gurjar M, Godbole MM, Poddar B, Singh RK.

J Intensive Care. 2013 Dec 20;1(1):14. doi: 10.1186/2052-0492-1-14. eCollection 2013.


Effects of short-term testosterone replacement on areal bone mineral density and bone turnover in young hypogonadal males.

Deb P, Gupta SK, Godbole MM.

Indian J Endocrinol Metab. 2012 Nov;16(6):947-51. doi: 10.4103/2230-8210.102997.


Calcitriol [1, 25[OH]2 D3] pre- and post-treatment suppresses inflammatory response to influenza A (H1N1) infection in human lung A549 epithelial cells.

Khare D, Godbole NM, Pawar SD, Mohan V, Pandey G, Gupta S, Kumar D, Dhole TN, Godbole MM.

Eur J Nutr. 2013 Jun;52(4):1405-15. doi: 10.1007/s00394-012-0449-7. Epub 2012 Sep 27.


Maternal thyroid hormone deficiency affects the fetal neocorticogenesis by reducing the proliferating pool, rate of neurogenesis and indirect neurogenesis.

Mohan V, Sinha RA, Pathak A, Rastogi L, Kumar P, Pal A, Godbole MM.

Exp Neurol. 2012 Oct;237(2):477-88. doi: 10.1016/j.expneurol.2012.07.019. Epub 2012 Aug 7.


A plausible explanation for enhanced bioavailability of P-gp substrates in presence of piperine: simulation for next generation of P-gp inhibitors.

Singh DV, Godbole MM, Misra K.

J Mol Model. 2013 Jan;19(1):227-38. doi: 10.1007/s00894-012-1535-8. Epub 2012 Aug 4.


Role of B₁₂ and homocysteine status in determining BMD and bone turnover in young Indians.

Haroon NN, Marwaha RK, Godbole MM, Gupta SK.

J Clin Densitom. 2012 Jul-Sep;15(3):366-73. doi: 10.1016/j.jocd.2012.01.006. Epub 2012 Apr 20.


Prenatal iodine deficiency results in structurally and functionally immature lungs in neonatal rats.

Godbole MM, Rao G, Paul BN, Mohan V, Singh P, Khare D, Babu S, Nath A, Singh PK, Tiwari S.

Am J Physiol Lung Cell Mol Physiol. 2012 May 15;302(10):L1037-43. doi: 10.1152/ajplung.00191.2011. Epub 2012 Mar 16.


Sodium iodide symporter, estrogen receptor, and progesterone receptor expression in carcinoma breast--an immunohistochemical analysis.

Tandon A, Shrivastava A, Kumar A, Prayaga AK, Sundaram C, Godbole MM.

Indian J Pathol Microbiol. 2011 Oct-Dec;54(4):745-51. doi: 10.4103/0377-4929.91514.


Inhibition of autophagy stimulate molecular iodine-induced apoptosis in hormone independent breast tumors.

Singh P, Godbole M, Rao G, Annarao S, Mitra K, Roy R, Ingle A, Agarwal G, Tiwari S.

Biochem Biophys Res Commun. 2011 Nov 11;415(1):181-6. doi: 10.1016/j.bbrc.2011.10.054. Epub 2011 Oct 18.


Human sodium iodide symporter (hNIS) in fibroadenoma breast--a immunohistochemical study.

Rai R, Shrivastava A, Tandon A, Godbole MM, Kumar S, Das V, Dwivedi V, Pal L.

Indian J Exp Biol. 2011 Feb;49(2):113-7.


Effect of hypothyroxinemia on thyroid hormone responsiveness and action during rat postnatal neocortical development.

Babu S, Sinha RA, Mohan V, Rao G, Pal A, Pathak A, Singh M, Godbole MM.

Exp Neurol. 2011 Mar;228(1):91-8. doi: 10.1016/j.expneurol.2010.12.012. Epub 2010 Dec 24.


Oral iron supplementation leads to oxidative imbalance in anemic women: a prospective study.

Tiwari AK, Mahdi AA, Chandyan S, Zahra F, Godbole MM, Jaiswar SP, Srivastava VK, Negi MP.

Clin Nutr. 2011 Apr;30(2):188-93. doi: 10.1016/j.clnu.2010.08.001.


Evidence of a bigenomic regulation of mitochondrial gene expression by thyroid hormone during rat brain development.

Sinha RA, Pathak A, Mohan V, Babu S, Pal A, Khare D, Godbole MM.

Biochem Biophys Res Commun. 2010 Jul 2;397(3):548-52. doi: 10.1016/j.bbrc.2010.05.154. Epub 2010 May 31.


Maternal thyroid hormone before the onset of fetal thyroid function regulates reelin and downstream signaling cascade affecting neocortical neuronal migration.

Pathak A, Sinha RA, Mohan V, Mitra K, Godbole MM.

Cereb Cortex. 2011 Jan;21(1):11-21. doi: 10.1093/cercor/bhq052. Epub 2010 Apr 5.


Effect of vitamin D supplementation on bone health parameters of healthy young Indian women.

Malhotra N, Mithal A, Gupta S, Shukla M, Godbole M.

Arch Osteoporos. 2009 Dec;4(1-2):47-53. Epub 2009 Jul 14.


Persistence of severe iodine-deficiency disorders despite universal salt iodization in an iodine-deficient area in northern India.

Yadav S, Gupta SK, Godbole MM, Jain M, Singh U, V Pavithran P, Boddula R, Mishra A, Shrivastava A, Tandon A, Ora M, Chowhan A, Shukla M, Yadav N, Babu S, Dubey M, Awasthi PK.

Public Health Nutr. 2010 Mar;13(3):424-9. doi: 10.1017/S1368980009990280. Epub 2009 Jun 11.


Autophonia in anorexia nervosa.

Godbole M, Key A.

Int J Eat Disord. 2010 Jul;43(5):480-2. doi: 10.1002/eat.20702.


Anti-apoptotic role of omega-3-fatty acids in developing brain: perinatal hypothyroid rat cerebellum as apoptotic model.

Sinha RA, Khare P, Rai A, Maurya SK, Pathak A, Mohan V, Nagar GK, Mudiam MK, Godbole MM, Bandyopadhyay S.

Int J Dev Neurosci. 2009 Jun;27(4):377-83. doi: 10.1016/j.ijdevneu.2009.02.003. Epub 2009 Mar 5.


Enhanced neuronal loss under perinatal hypothyroidism involves impaired neurotrophic signaling and increased proteolysis of p75(NTR).

Sinha RA, Pathak A, Kumar A, Tiwari M, Shrivastava A, Godbole MM.

Mol Cell Neurosci. 2009 Mar;40(3):354-64. doi: 10.1016/j.mcn.2008.12.001. Epub 2008 Dec 16.


Maternal thyroid hormone: a strong repressor of neuronal nitric oxide synthase in rat embryonic neocortex.

Sinha RA, Pathak A, Mohan V, Bandyopadhyay S, Rastogi L, Godbole MM.

Endocrinology. 2008 Sep;149(9):4396-401. doi: 10.1210/en.2007-1617. Epub 2008 May 8.


Pathophysiological basis for thyrotoxicosis as an aggravating factor in post-ischemic brain injury in rats.

Rastogi L, Gupta S, Godbole MM.

J Endocrinol. 2008 Feb;196(2):335-41. doi: 10.1677/JOE-07-0483.

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