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Items: 23


Increased TNFR1 expression and signaling in injured peripheral nerves of mice with reduced BACE1 activity.

Liu L, Fissel JA, Tasnim A, Borzan J, Gocke A, Calabresi PA, Farah MH.

Neurobiol Dis. 2016 Sep;93:21-7. doi: 10.1016/j.nbd.2016.04.002. Epub 2016 Apr 11.


Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis.

Sotirchos ES, Bhargava P, Eckstein C, Van Haren K, Baynes M, Ntranos A, Gocke A, Steinman L, Mowry EM, Calabresi PA.

Neurology. 2016 Jan 26;86(4):382-90. doi: 10.1212/WNL.0000000000002316. Epub 2015 Dec 30.


Antigenic Stimulation of Kv1.3-Deficient Th Cells Gives Rise to a Population of Foxp3-Independent T Cells with Suppressive Properties.

Grishkan IV, Tosi DM, Bowman MD, Harary M, Calabresi PA, Gocke AR.

J Immunol. 2015 Aug 15;195(4):1399-1407. doi: 10.4049/jimmunol.1403024. Epub 2015 Jul 6.


Transfer of myelin-reactive th17 cells impairs endogenous remyelination in the central nervous system of cuprizone-fed mice.

Baxi EG, DeBruin J, Tosi DM, Grishkan IV, Smith MD, Kirby LA, Strasburger HJ, Fairchild AN, Calabresi PA, Gocke AR.

J Neurosci. 2015 Jun 3;35(22):8626-39. doi: 10.1523/JNEUROSCI.3817-14.2015.


1,25-Dihydroxyvitamin D3 impairs the differentiation of effector memory T cells in vitro in multiple sclerosis patients and healthy controls.

Bhargava P, Gocke A, Calabresi PA.

J Neuroimmunol. 2015 Feb 15;279:20-4. doi: 10.1016/j.jneuroim.2014.12.018. Epub 2015 Jan 3.


FTY720 impairs CD8 T-cell function independently of the sphingosine-1-phosphate pathway.

Ntranos A, Hall O, Robinson DP, Grishkan IV, Schott JT, Tosi DM, Klein SL, Calabresi PA, Gocke AR.

J Neuroimmunol. 2014 May 15;270(1-2):13-21. doi: 10.1016/j.jneuroim.2014.03.007. Epub 2014 Mar 11.


1,25-Dihydroxyvitamin D3 selectively and reversibly impairs T helper-cell CNS localization.

Grishkan IV, Fairchild AN, Calabresi PA, Gocke AR.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21101-6. doi: 10.1073/pnas.1306072110. Epub 2013 Dec 9.


Helper T cells down-regulate CD4 expression upon chronic stimulation giving rise to double-negative T cells.

Grishkan IV, Ntranos A, Calabresi PA, Gocke AR.

Cell Immunol. 2013 Jul-Aug;284(1-2):68-74. doi: 10.1016/j.cellimm.2013.06.011. Epub 2013 Jul 2.


Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.

Hu L, Wang T, Gocke AR, Nath A, Zhang H, Margolick JB, Whartenby KA, Calabresi PA.

PLoS One. 2013;8(1):e54267. doi: 10.1371/journal.pone.0054267. Epub 2013 Jan 30.


Expression of CCR7 and CD45RA in CD4+ and CD8+ subsets in cerebrospinal fluid of 134 patients with inflammatory and non-inflammatory neurological diseases.

Mullen KM, Gocke AR, Allie R, Ntranos A, Grishkan IV, Pardo C, Calabresi PA.

J Neuroimmunol. 2012 Aug 15;249(1-2):86-92. doi: 10.1016/j.jneuroim.2012.04.017. Epub 2012 May 24.


Kv1.3 deletion biases T cells toward an immunoregulatory phenotype and renders mice resistant to autoimmune encephalomyelitis.

Gocke AR, Lebson LA, Grishkan IV, Hu L, Nguyen HM, Whartenby KA, Chandy KG, Calabresi PA.

J Immunol. 2012 Jun 15;188(12):5877-86. doi: 10.4049/jimmunol.1103095. Epub 2012 May 11.


Functional blockade of the voltage-gated potassium channel Kv1.3 mediates reversion of T effector to central memory lymphocytes through SMAD3/p21cip1 signaling.

Hu L, Gocke AR, Knapp E, Rosenzweig JM, Grishkan IV, Baxi EG, Zhang H, Margolick JB, Whartenby KA, Calabresi PA.

J Biol Chem. 2012 Jan 6;287(2):1261-8. doi: 10.1074/jbc.M111.296798. Epub 2011 Nov 22.


Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells.

Ghoreschi K, Brück J, Kellerer C, Deng C, Peng H, Rothfuss O, Hussain RZ, Gocke AR, Respa A, Glocova I, Valtcheva N, Alexander E, Feil S, Feil R, Schulze-Osthoff K, Rupec RA, Lovett-Racke AE, Dringen R, Racke MK, Röcken M.

J Exp Med. 2011 Oct 24;208(11):2291-303. doi: 10.1084/jem.20100977. Epub 2011 Oct 10.


Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening.

Reddy MM, Wilson R, Wilson J, Connell S, Gocke A, Hynan L, German D, Kodadek T.

Cell. 2011 Jan 7;144(1):132-42. doi: 10.1016/j.cell.2010.11.054.


Cutting edge: The transcription factor Kruppel-like factor 4 regulates the differentiation of Th17 cells independently of RORγt.

Lebson L, Gocke A, Rosenzweig J, Alder J, Civin C, Calabresi PA, Whartenby KA.

J Immunol. 2010 Dec 15;185(12):7161-4. doi: 10.4049/jimmunol.1002750. Epub 2010 Nov 12.


Silencing Nogo-A promotes functional recovery in demyelinating disease.

Yang Y, Liu Y, Wei P, Peng H, Winger R, Hussain RZ, Ben LH, Cravens PD, Gocke AR, Puttaparthi K, Racke MK, McTigue DM, Lovett-Racke AE.

Ann Neurol. 2010 Apr;67(4):498-507. doi: 10.1002/ana.21935.


Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling.

Hu W, Nessler S, Hemmer B, Eagar TN, Kane LP, Leliveld SR, Müller-Schiffmann A, Gocke AR, Lovett-Racke A, Ben LH, Hussain RZ, Breil A, Elliott JL, Puttaparthi K, Cravens PD, Singh MP, Petsch B, Stitz L, Racke MK, Korth C, Stüve O.

Brain. 2010 Feb;133(Pt 2):375-88. doi: 10.1093/brain/awp298. Epub 2010 Feb 9.


Isolation of antagonists of antigen-specific autoimmune T cell proliferation.

Gocke AR, Udugamasooriya DG, Archer CT, Lee J, Kodadek T.

Chem Biol. 2009 Nov 25;16(11):1133-9. doi: 10.1016/j.chembiol.2009.10.011.


Transcriptional modulation of the immune response by peroxisome proliferator-activated receptor-{alpha} agonists in autoimmune disease.

Gocke AR, Hussain RZ, Yang Y, Peng H, Weiner J, Ben LH, Drew PD, Stuve O, Lovett-Racke AE, Racke MK.

J Immunol. 2009 Apr 1;182(7):4479-87. doi: 10.4049/jimmunol.0713927.


PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis.

Yang Y, Gocke AR, Lovett-Racke A, Drew PD, Racke MK.

PPAR Res. 2008;2008:546753. doi: 10.1155/2008/546753.


T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity.

Gocke AR, Cravens PD, Ben LH, Hussain RZ, Northrop SC, Racke MK, Lovett-Racke AE.

J Immunol. 2007 Feb 1;178(3):1341-8.


Nuclear receptors and autoimmune disease: the potential of PPAR agonists to treat multiple sclerosis.

Racke MK, Gocke AR, Muir M, Diab A, Drew PD, Lovett-Racke AE.

J Nutr. 2006 Mar;136(3):700-3. Review.


Therapeutic potential of small interfering RNA for central nervous system diseases.

Lovett-Racke AE, Cravens PD, Gocke AR, Racke MK, Stüve O.

Arch Neurol. 2005 Dec;62(12):1810-3. Review. No abstract available.


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