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Items: 1 to 50 of 59

1.

7 T MRI reveals hippocampal structural abnormalities associated with memory intrusions in childhood-onset schizophrenia.

Zhou D, Liu S, Zhou X, Berman R, Broadnax D, Gochman P, Rapoport J, Thomas A.

Schizophr Res. 2018 Dec;202:431-432. doi: 10.1016/j.schres.2018.07.023. Epub 2018 Jul 18. No abstract available.

PMID:
30029830
2.

Reduced Functional Brain Activation and Connectivity During a Working Memory Task in Childhood-Onset Schizophrenia.

Loeb FF, Zhou X, Craddock KES, Shora L, Broadnax DD, Gochman P, Clasen LS, Lalonde FM, Berman RA, Berman KF, Rapoport JL, Liu S.

J Am Acad Child Adolesc Psychiatry. 2018 Mar;57(3):166-174. doi: 10.1016/j.jaac.2017.12.009. Epub 2017 Dec 28.

3.

Attenuated resting-state functional connectivity in patients with childhood- and adult-onset schizophrenia.

Watsky RE, Gotts SJ, Berman RA, McAdams HM, Zhou X, Greenstein D, Lalonde FM, Gochman P, Clasen LS, Shora L, Ordóñez AE, Gogtay N, Martin A, Barch DM, Rapoport JL, Liu S.

Schizophr Res. 2018 Jul;197:219-225. doi: 10.1016/j.schres.2018.01.003. Epub 2018 Jan 6.

4.

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.

Hoffman GE, Hartley BJ, Flaherty E, Ladran I, Gochman P, Ruderfer DM, Stahl EA, Rapoport J, Sklar P, Brennand KJ.

Nat Commun. 2017 Dec 20;8(1):2225. doi: 10.1038/s41467-017-02330-5.

5.

Symptom dimensions and subgroups in childhood-onset schizophrenia.

Craddock KES, Zhou X, Liu S, Gochman P, Dickinson D, Rapoport JL.

Schizophr Res. 2018 Jul;197:71-77. doi: 10.1016/j.schres.2017.10.045. Epub 2017 Nov 13.

6.

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells.

Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, Cagney G, Rapoport J, Gage FH, Dudley JT, Sklar P, Mattheisen M, Cotter D, Fang G, Brennand KJ.

Cell Rep. 2017 Sep 5;20(10):2525. doi: 10.1016/j.celrep.2017.08.073. No abstract available.

7.

Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.

Xu J, Hartley BJ, Kurup P, Phillips A, Topol A, Xu M, Ononenyi C, Foscue E, Ho SM, Baguley TD, Carty N, Barros CS, Müller U, Gupta S, Gochman P, Rapoport J, Ellman JA, Pittenger C, Aronow B, Nairn AC, Nestor MW, Lombroso PJ, Brennand KJ.

Mol Psychiatry. 2018 Feb;23(2):271-281. doi: 10.1038/mp.2016.163. Epub 2016 Oct 18.

8.

Lack of Gender-Related Differences in Childhood-Onset Schizophrenia.

Ordóñez AE, Loeb FF, Zhou X, Shora L, Berman RA, Broadnax DD, Gochman P, Liu S, Rapoport JL.

J Am Acad Child Adolesc Psychiatry. 2016 Sep;55(9):792-9. doi: 10.1016/j.jaac.2016.05.022. Epub 2016 Jul 1.

9.

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells.

Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, Cagney G, Rapoport J, Gage FH, Dudley JT, Sklar P, Mattheisen M, Cotter D, Fang G, Brennand KJ.

Cell Rep. 2016 May 3;15(5):1024-1036. doi: 10.1016/j.celrep.2016.03.090. Epub 2016 Apr 21. Erratum in: Cell Rep. 2017 Sep 5;20(10):2525.

10.

15q13.3 duplication in two patients with childhood-onset schizophrenia.

Zhou D, Gochman P, Broadnax DD, Rapoport JL, Ahn K.

Am J Med Genet B Neuropsychiatr Genet. 2016 Sep;171(6):777-83. doi: 10.1002/ajmg.b.32439. Epub 2016 Mar 10.

11.

Severity of Cortical Thinning Correlates With Schizophrenia Spectrum Symptoms.

Watsky RE, Pollard KL, Greenstein D, Shora L, Dillard-Broadnax D, Gochman P, Clasen LS, Berman RA, Rapoport JL, Gogtay N, Ordóñez AE.

J Am Acad Child Adolesc Psychiatry. 2016 Feb;55(2):130-136. doi: 10.1016/j.jaac.2015.11.008. Epub 2015 Nov 26.

12.

Strong Treatment Response and High Maintenance Rates of Clozapine in Childhood-Onset Schizophrenia.

Kasoff LI, Ahn K, Gochman P, Broadnax DD, Rapoport JL.

J Child Adolesc Psychopharmacol. 2016 Jun;26(5):428-35. doi: 10.1089/cap.2015.0103. Epub 2016 Jan 19.

13.

Hippocampal volume change relates to clinical outcome in childhood-onset schizophrenia.

Anvari AA, Friedman LA, Greenstein D, Gochman P, Gogtay N, Rapoport JL.

Psychol Med. 2015;45(12):2667-74. doi: 10.1017/S0033291715000677. Epub 2015 May 4.

PMID:
25936396
14.

Looking for childhood-onset schizophrenia: diagnostic algorithms for classifying children and adolescents with psychosis.

Greenstein D, Kataria R, Gochman P, Dasgupta A, Malley JD, Rapoport J, Gogtay N.

J Child Adolesc Psychopharmacol. 2014 Sep;24(7):366-73. doi: 10.1089/cap.2013.0139. Epub 2014 Jul 14.

15.

At the boundary of the self: the insular cortex in patients with childhood-onset schizophrenia, their healthy siblings, and normal volunteers.

Moran ME, Weisinger B, Ludovici K, McAdams H, Greenstein D, Gochman P, Miller R, Clasen L, Rapoport J, Gogtay N.

Int J Dev Neurosci. 2014 Feb;32:58-63. doi: 10.1016/j.ijdevneu.2013.05.010. Epub 2013 Jun 11.

PMID:
23770018
16.

High rate of disease-related copy number variations in childhood onset schizophrenia.

Ahn K, Gotay N, Andersen TM, Anvari AA, Gochman P, Lee Y, Sanders S, Guha S, Darvasi A, Glessner JT, Hakonarson H, Lencz T, State MW, Shugart YY, Rapoport JL.

Mol Psychiatry. 2014 May;19(5):568-72. doi: 10.1038/mp.2013.59. Epub 2013 May 21.

17.

Risk factors for neutropenia in clozapine-treated children and adolescents with childhood-onset schizophrenia.

Maher KN, Tan M, Tossell JW, Weisinger B, Gochman P, Miller R, Greenstein D, Overman GP, Rapoport JL, Gogtay N.

J Child Adolesc Psychopharmacol. 2013 Mar;23(2):110-6. doi: 10.1089/cap.2011.0136.

18.

Childhood-onset schizophrenia: the challenge of diagnosis.

Gochman P, Miller R, Rapoport JL.

Curr Psychiatry Rep. 2011 Oct;13(5):321-2. doi: 10.1007/s11920-011-0212-4.

19.

Childhood onset schizophrenia: high rate of visual hallucinations.

David CN, Greenstein D, Clasen L, Gochman P, Miller R, Tossell JW, Mattai AA, Gogtay N, Rapoport JL.

J Am Acad Child Adolesc Psychiatry. 2011 Jul;50(7):681-686.e3. doi: 10.1016/j.jaac.2011.03.020. Epub 2011 Jun 11.

20.

Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls.

Raznahan A, Greenstein D, Lee Y, Long R, Clasen L, Gochman P, Addington A, Giedd JN, Rapoport JL, Gogtay N.

Neuroimage. 2011 Aug 15;57(4):1517-23. doi: 10.1016/j.neuroimage.2011.05.032. Epub 2011 May 15.

21.

A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders.

Addington AM, Gauthier J, Piton A, Hamdan FF, Raymond A, Gogtay N, Miller R, Tossell J, Bakalar J, Inoff-Germain G, Gochman P, Long R, Rapoport JL, Rouleau GA.

Mol Psychiatry. 2011 Mar;16(3):238-9. doi: 10.1038/mp.2010.59. Epub 2010 May 18. No abstract available. Erratum in: Mol Psychiatry. 2012 Apr;17(4):468. Germain, G [corrected to Inoff-Germain, G].

22.

Sex chromosome anomalies in childhood onset schizophrenia: an update.

Eckstrand K, Addington AM, Stromberg T, Merriman B, Miller R, Gochman P, Long R, Dutra A, Chen Z, Meltzer P, Nelson SF, Rapoport JL.

Mol Psychiatry. 2008 Oct;13(10):910-1. doi: 10.1038/mp.2008.67. No abstract available.

23.

Remission status and cortical thickness in childhood-onset schizophrenia.

Greenstein DK, Wolfe S, Gochman P, Rapoport JL, Gogtay N.

J Am Acad Child Adolesc Psychiatry. 2008 Oct;47(10):1133-40. doi: 10.1097/CHI.0b013e3181825b0c.

24.

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia.

Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, Cooper GM, Nord AS, Kusenda M, Malhotra D, Bhandari A, Stray SM, Rippey CF, Roccanova P, Makarov V, Lakshmi B, Findling RL, Sikich L, Stromberg T, Merriman B, Gogtay N, Butler P, Eckstrand K, Noory L, Gochman P, Long R, Chen Z, Davis S, Baker C, Eichler EE, Meltzer PS, Nelson SF, Singleton AB, Lee MK, Rapoport JL, King MC, Sebat J.

Science. 2008 Apr 25;320(5875):539-43. doi: 10.1126/science.1155174. Epub 2008 Mar 27.

25.

Clozapine treatment of childhood-onset schizophrenia: evaluation of effectiveness, adverse effects, and long-term outcome.

Sporn AL, Vermani A, Greenstein DK, Bobb AJ, Spencer EP, Clasen LS, Tossell JW, Stayer CC, Gochman PA, Lenane MC, Rapoport JL, Gogtay N.

J Am Acad Child Adolesc Psychiatry. 2007 Oct;46(10):1349-1356. doi: 10.1097/chi.0b013e31812eed10.

PMID:
17885577
26.

Cortical brain development in nonpsychotic siblings of patients with childhood-onset schizophrenia.

Gogtay N, Greenstein D, Lenane M, Clasen L, Sharp W, Gochman P, Butler P, Evans A, Rapoport J.

Arch Gen Psychiatry. 2007 Jul;64(7):772-80.

PMID:
17606811
27.

Childhood onset schizophrenia: cortical brain abnormalities as young adults.

Greenstein D, Lerch J, Shaw P, Clasen L, Giedd J, Gochman P, Rapoport J, Gogtay N.

J Child Psychol Psychiatry. 2006 Oct;47(10):1003-12.

PMID:
17073979
28.

Neuregulin 1 (8p12) and childhood-onset schizophrenia: susceptibility haplotypes for diagnosis and brain developmental trajectories.

Addington AM, Gornick MC, Shaw P, Seal J, Gogtay N, Greenstein D, Clasen L, Coffey M, Gochman P, Long R, Rapoport JL.

Mol Psychiatry. 2007 Feb;12(2):195-205. Epub 2006 Oct 10.

PMID:
17033632
29.

Childhood-onset schizophrenia: A double-blind, randomized clozapine-olanzapine comparison.

Shaw P, Sporn A, Gogtay N, Overman GP, Greenstein D, Gochman P, Tossell JW, Lenane M, Rapoport JL.

Arch Gen Psychiatry. 2006 Jul;63(7):721-30.

PMID:
16818861
30.

Segmental uniparental isodisomy on 5q32-qter in a patient with childhood-onset schizophrenia.

Seal JL, Gornick MC, Gogtay N, Shaw P, Greenstein DK, Coffey M, Gochman PA, Stromberg T, Chen Z, Merriman B, Nelson SF, Brooks J, Arepalli S, Wavrant-De Vrièze F, Hardy J, Rapoport JL, Addington AM.

J Med Genet. 2006 Nov;43(11):887-92. Epub 2006 Jun 8.

31.

Sleep disturbances in childhood-onset schizophrenia.

Mattai AA, Tossell J, Greenstein DK, Addington A, Clasen LS, Gornick MC, Seal J, Inoff-Germain G, Gochman PA, Lenane M, Rapoport JL, Gogtay N.

Schizophr Res. 2006 Sep;86(1-3):123-9. Epub 2006 May 30.

PMID:
16730952
32.

Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophrenia.

Vidal CN, Rapoport JL, Hayashi KM, Geaga JA, Sui Y, McLemore LE, Alaghband Y, Giedd JN, Gochman P, Blumenthal J, Gogtay N, Nicolson R, Toga AW, Thompson PM.

Arch Gen Psychiatry. 2006 Jan;63(1):25-34.

PMID:
16389194
33.

Dysbindin (DTNBP1, 6p22.3) is associated with childhood-onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS).

Gornick MC, Addington AM, Sporn A, Gogtay N, Greenstein D, Lenane M, Gochman P, Ordonez A, Balkissoon R, Vakkalanka R, Weinberger DR, Rapoport JL, Straub RE.

J Autism Dev Disord. 2005 Dec;35(6):831-8.

PMID:
16283082
34.

Hormonal correlates of clozapine-induced weight gain in psychotic children: an exploratory study.

Sporn AL, Bobb AJ, Gogtay N, Stevens H, Greenstein DK, Clasen LS, Tossell JW, Nugent T, Gochman PA, Sharp WS, Mattai A, Lenane MC, Yanovski JA, Rapoport JL.

J Am Acad Child Adolesc Psychiatry. 2005 Sep;44(9):925-33.

PMID:
16113621
35.

Multidimensionally impaired: the good news.

Stayer C, Sporn A, Gogtay N, Tossell JW, Lenane M, Gochman P, Greenstein D, Sharp W, Rapoport JL.

J Child Adolesc Psychopharmacol. 2005 Jun;15(3):510-9.

PMID:
16092914
36.

IQ stabilization in childhood-onset schizophrenia.

Gochman PA, Greenstein D, Sporn A, Gogtay N, Keller B, Shaw P, Rapoport JL.

Schizophr Res. 2005 Sep 15;77(2-3):271-7.

PMID:
15913958
37.

Childhood-onset schizophrenia: smooth pursuit eye-tracking dysfunction in family members.

Sporn A, Greenstein D, Gogtay N, Sailer F, Hommer DW, Rawlings R, Nicolson R, Egan MF, Lenane M, Gochman P, Weinberger DR, Rapoport JL.

Schizophr Res. 2005 Mar 1;73(2-3):243-52.

PMID:
15653267
38.

Stimulant drug treatment in childhood-onset schizophrenia with comorbid ADHD: an open-label case series.

Tossell JW, Greenstein DK, Davidson AL, Job SB, Gochman P, Lenane M, Nugent Iii TF, Gogtay N, Sporn AL, Rapoport JL.

J Child Adolesc Psychopharmacol. 2004 Fall;14(3):448-54.

PMID:
15650502
39.

GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss.

Addington AM, Gornick M, Duckworth J, Sporn A, Gogtay N, Bobb A, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Vakkalanka RK, Weinberger DR, Rapoport JL, Straub RE.

Mol Psychiatry. 2005 Jun;10(6):581-8.

PMID:
15505639
40.

Childhood onset schizophrenia: familial neurocognitive measures.

Gochman PA, Greenstein D, Sporn A, Gogtay N, Nicolson R, Keller A, Lenane M, Brookner F, Rapoport JL.

Schizophr Res. 2004 Nov 1;71(1):43-7.

PMID:
15374571
41.

Looking for childhood schizophrenia: case series of false positives.

Stayer C, Sporn A, Gogtay N, Tossell J, Lenane M, Gochman P, Rapoport JL.

J Am Acad Child Adolesc Psychiatry. 2004 Aug;43(8):1026-9.

PMID:
15266198
42.

Pervasive developmental disorder and childhood-onset schizophrenia: comorbid disorder or a phenotypic variant of a very early onset illness?

Sporn AL, Addington AM, Gogtay N, Ordoñez AE, Gornick M, Clasen L, Greenstein D, Tossell JW, Gochman P, Lenane M, Sharp WS, Straub RE, Rapoport JL.

Biol Psychiatry. 2004 May 15;55(10):989-94.

PMID:
15121482
43.

Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified.

Addington AM, Gornick M, Sporn AL, Gogtay N, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Vakkalanka RK, Weinberger DR, Straub RE, Rapoport JL.

Biol Psychiatry. 2004 May 15;55(10):976-80.

PMID:
15121480
44.

Comparison of progressive cortical gray matter loss in childhood-onset schizophrenia with that in childhood-onset atypical psychoses.

Gogtay N, Sporn A, Clasen LS, Nugent TF 3rd, Greenstein D, Nicolson R, Giedd JN, Lenane M, Gochman P, Evans A, Rapoport JL.

Arch Gen Psychiatry. 2004 Jan;61(1):17-22.

PMID:
14706940
45.

22q11 deletion syndrome in childhood onset schizophrenia: an update.

Sporn A, Addington A, Reiss AL, Dean M, Gogtay N, Potocnik U, Greenstein D, Hallmayer J, Gochman P, Lenane M, Baker N, Tossell J, Rapoport JL.

Mol Psychiatry. 2004 Mar;9(3):225-6. No abstract available.

PMID:
14699434
46.

Clozapine-induced neutropenia in children: management with lithium carbonate.

Sporn A, Gogtay N, Ortiz-Aguayo R, Alfaro C, Tossell J, Lenane M, Gochman P, Rapoport JL.

J Child Adolesc Psychopharmacol. 2003 Fall;13(3):401-4.

PMID:
14642024
47.

Progressive brain volume loss during adolescence in childhood-onset schizophrenia.

Sporn AL, Greenstein DK, Gogtay N, Jeffries NO, Lenane M, Gochman P, Clasen LS, Blumenthal J, Giedd JN, Rapoport JL.

Am J Psychiatry. 2003 Dec;160(12):2181-9.

PMID:
14638588
48.

Structural brain MRI abnormalities in healthy siblings of patients with childhood-onset schizophrenia.

Gogtay N, Sporn A, Clasen LS, Greenstein D, Giedd JN, Lenane M, Gochman PA, Zijdenbos A, Rapoport JL.

Am J Psychiatry. 2003 Mar;160(3):569-71.

PMID:
12611841
49.

Parental schizophrenia spectrum disorders in childhood-onset and adult-onset schizophrenia.

Nicolson R, Brookner FB, Lenane M, Gochman P, Ingraham LJ, Egan MF, Kendler KS, Pickar D, Weinberger DR, Rapoport JL.

Am J Psychiatry. 2003 Mar;160(3):490-5.

PMID:
12611830
50.

Correlation of antipsychotic and prolactin concentrations in children and adolescents acutely treated with haloperidol, clozapine, or olanzapine.

Alfaro CL, Wudarsky M, Nicolson R, Gochman P, Sporn A, Lenane M, Rapoport JL.

J Child Adolesc Psychopharmacol. 2002 Summer;12(2):83-91.

PMID:
12188977

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