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Items: 1 to 50 of 168


α-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY.

Sierra JC, Suarez G, Piazuelo MB, Luis PB, Baker DR, Romero-Gallo J, Barry DP, Schneider C, Morgan DR, Peek RM Jr, Gobert AP, Wilson KT.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5077-5085. doi: 10.1073/pnas.1814497116. Epub 2019 Feb 25.


Outcomes after salvage radical prostatectomy and first-line radiation therapy or HIFU for recurrent localized prostate cancer: results from a multicenter study.

Clery R, Grande P, Seisen T, Gobert A, Duquesne I, Villers A, Olivier J, Bernhard JC, Robert G, Beauval JB, Prudhomme T, Bruyère F, Lainé-Caroff P, Waltregny D, Guillonneau B, Panarello D, Ruffion A, De Bayser H, de La Taille A, Roupret M.

World J Urol. 2019 Feb 21. doi: 10.1007/s00345-019-02683-0. [Epub ahead of print]


Bladder mapping of tumour recurrence after radical nephroureterectomy for upper tract urothelial carcinoma and its influence on oncological outcomes.

Belhadj Y, Grande P, Seisen T, Gobert A, Gomez FD, Cussenot O, Roupret M.

BJU Int. 2019 Apr;123(4):618-623. doi: 10.1111/bju.14647. Epub 2019 Jan 6.


HIV-associated cancers: the role of a unique multidisciplinary board to optimize patient's care behalf the CANCERVIH Group.

Gobert A, Spano JP, Cadranel J.

Med Oncol. 2018 Dec 5;36(1):13. doi: 10.1007/s12032-018-1224-2.


Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study.

Salem JE, Manouchehri A, Moey M, Lebrun-Vignes B, Bastarache L, Pariente A, Gobert A, Spano JP, Balko JM, Bonaca MP, Roden DM, Johnson DB, Moslehi JJ.

Lancet Oncol. 2018 Dec;19(12):1579-1589. doi: 10.1016/S1470-2045(18)30608-9. Epub 2018 Nov 12.


RNA uridylation and decay in plants.

de Almeida C, Scheer H, Gobert A, Fileccia V, Martinelli F, Zuber H, Gagliardi D.

Philos Trans R Soc Lond B Biol Sci. 2018 Nov 5;373(1762). pii: 20180163. doi: 10.1098/rstb.2018.0163. Review.


Helicobacter: Inflammation, immunology, and vaccines.

Blosse A, Lehours P, Wilson KT, Gobert AP.

Helicobacter. 2018 Sep;23 Suppl 1:e12517. doi: 10.1111/hel.12517. Review.


Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis.

Coburn LA, Singh K, Asim M, Barry DP, Allaman MM, Al-Greene NT, Hardbower DM, Polosukhina D, Williams CS, Delgado AG, Piazuelo MB, Washington MK, Gobert AP, Wilson KT.

Oncogene. 2019 Feb;38(7):1067-1079. doi: 10.1038/s41388-018-0492-9. Epub 2018 Sep 10.


[Radiotherapy for HIV-infected patients].

Quéro L, Gobert A, Spano JP.

Cancer Radiother. 2018 Oct;22(6-7):496-501. doi: 10.1016/j.canrad.2018.06.007. Epub 2018 Aug 4. Review. French.


Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection.

Gobert AP, Al-Greene NT, Singh K, Coburn LA, Sierra JC, Verriere TG, Luis PB, Schneider C, Asim M, Allaman MM, Barry DP, Cleveland JL, Destefano Shields CE, Casero RA Jr, Washington MK, Piazuelo MB, Wilson KT.

Front Immunol. 2018 Jun 5;9:1242. doi: 10.3389/fimmu.2018.01242. eCollection 2018.


BVES is required for maintenance of colonic epithelial integrity in experimental colitis by modifying intestinal permeability.

Choksi YA, Reddy VK, Singh K, Barrett CW, Short SP, Parang B, Keating CE, Thompson JJ, Verriere TG, Brown RE, Piazuelo MB, Bader DM, Washington MK, Mittal MK, Brand T, Gobert AP, Coburn LA, Wilson KT, Williams CS.

Mucosal Immunol. 2018 Sep;11(5):1363-1374. doi: 10.1038/s41385-018-0043-2. Epub 2018 Jun 15.


Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.

Singh K, Coburn LA, Asim M, Barry DP, Allaman MM, Shi C, Washington MK, Luis PB, Schneider C, Delgado AG, Piazuelo MB, Cleveland JL, Gobert AP, Wilson KT.

Cancer Res. 2018 Aug 1;78(15):4303-4315. doi: 10.1158/0008-5472.CAN-18-0116. Epub 2018 May 31.


[HIV and cancer : What's new in 2017?]

Gobert A, Veyri M, Poizot-Martin I, Lavolé A, Solas C, Paliche R, Katlama C, Costagliola D, Spano JP.

Bull Cancer. 2018 Mar;105(3):256-262. doi: 10.1016/j.bulcan.2018.02.002. Epub 2018 Mar 13. Review. French.


RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities.

Sikorska N, Zuber H, Gobert A, Lange H, Gagliardi D.

Nat Commun. 2017 Dec 18;8(1):2162. doi: 10.1038/s41467-017-02066-2.


Non-Saccharomyces Yeasts Nitrogen Source Preferences: Impact on Sequential Fermentation and Wine Volatile Compounds Profile.

Gobert A, Tourdot-Maréchal R, Morge C, Sparrow C, Liu Y, Quintanilla-Casas B, Vichi S, Alexandre H.

Front Microbiol. 2017 Nov 6;8:2175. doi: 10.3389/fmicb.2017.02175. eCollection 2017.


Trypanosoma musculi Infection in Mice Critically Relies on Mannose Receptor-Mediated Arginase Induction by a TbKHC1 Kinesin H Chain Homolog.

Nzoumbou-Boko R, De Muylder G, Semballa S, Lecordier L, Dauchy FA, Gobert AP, Holzmuller P, Lemesre JL, Bras-Gonçalves R, Barnabé C, Courtois P, Daulouède S, Beschin A, Pays E, Vincendeau P.

J Immunol. 2017 Sep 1;199(5):1762-1771. doi: 10.4049/jimmunol.1700179. Epub 2017 Jul 24.


Biophysical analysis of Arabidopsis protein-only RNase P alone and in complex with tRNA provides a refined model of tRNA binding.

Pinker F, Schelcher C, Fernandez-Millan P, Gobert A, Birck C, Thureau A, Roblin P, Giegé P, Sauter C.

J Biol Chem. 2017 Aug 25;292(34):13904-13913. doi: 10.1074/jbc.M117.782078. Epub 2017 Jul 10.


Effect of CO2 on Peroxynitrite-Mediated Bacteria Killing: Response to Tsikas et al.

Gobert AP, Wilson KT.

Trends Microbiol. 2017 Aug;25(8):602-603. doi: 10.1016/j.tim.2017.05.009. Epub 2017 Jun 10. No abstract available.


The NAG Sensor NagC Regulates LEE Gene Expression and Contributes to Gut Colonization by Escherichia coli O157:H7.

Le Bihan G, Sicard JF, Garneau P, Bernalier-Donadille A, Gobert AP, Garrivier A, Martin C, Hay AG, Beaudry F, Harel J, Jubelin G.

Front Cell Infect Microbiol. 2017 Apr 24;7:134. doi: 10.3389/fcimb.2017.00134. eCollection 2017.


Epidermal growth factor receptor inhibition downregulates Helicobacter pylori-induced epithelial inflammatory responses, DNA damage and gastric carcinogenesis.

Sierra JC, Asim M, Verriere TG, Piazuelo MB, Suarez G, Romero-Gallo J, Delgado AG, Wroblewski LE, Barry DP, Peek RM Jr, Gobert AP, Wilson KT.

Gut. 2018 Jul;67(7):1247-1260. doi: 10.1136/gutjnl-2016-312888. Epub 2017 May 4.


EGFR-mediated macrophage activation promotes colitis-associated tumorigenesis.

Hardbower DM, Coburn LA, Asim M, Singh K, Sierra JC, Barry DP, Gobert AP, Piazuelo MB, Washington MK, Wilson KT.

Oncogene. 2017 Jul 6;36(27):3807-3819. doi: 10.1038/onc.2017.23. Epub 2017 Mar 6.


Human and Helicobacter pylori Interactions Determine the Outcome of Gastric Diseases.

Gobert AP, Wilson KT.

Curr Top Microbiol Immunol. 2017;400:27-52. doi: 10.1007/978-3-319-50520-6_2. Review.


Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.

Hardbower DM, Asim M, Luis PB, Singh K, Barry DP, Yang C, Steeves MA, Cleveland JL, Schneider C, Piazuelo MB, Gobert AP, Wilson KT.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E751-E760. doi: 10.1073/pnas.1614958114. Epub 2017 Jan 17.


The human intestinal microbiota of constipated-predominant irritable bowel syndrome patients exhibits anti-inflammatory properties.

Gobert AP, Sagrestani G, Delmas E, Wilson KT, Verriere TG, Dapoigny M, Del'homme C, Bernalier-Donadille A.

Sci Rep. 2016 Dec 16;6:39399. doi: 10.1038/srep39399.


The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria.

Singh K, Al-Greene NT, Verriere TG, Coburn LA, Asim M, Barry DP, Allaman MM, Hardbower DM, Delgado AG, Piazuelo MB, Vallance BA, Gobert AP, Wilson KT.

PLoS Pathog. 2016 Oct 26;12(10):e1005984. doi: 10.1371/journal.ppat.1005984. eCollection 2016 Oct.


Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise.

Gobert AP, Wilson KT.

Free Radic Biol Med. 2017 Apr;105:16-27. doi: 10.1016/j.freeradbiomed.2016.09.024. Epub 2016 Sep 25. Review.


A secretome view of colonisation factors in Shiga toxin-encoding Escherichia coli (STEC): from enterohaemorrhagic E. coli (EHEC) to related enteropathotypes.

Monteiro R, Ageorges V, Rojas-Lopez M, Schmidt H, Weiss A, Bertin Y, Forano E, Jubelin G, Henderson IR, Livrelli V, Gobert AP, Rosini R, Soriani M, Desvaux M.

FEMS Microbiol Lett. 2016 Aug;363(16). pii: fnw179. doi: 10.1093/femsle/fnw179. Epub 2016 Jul 26. Review.


Transfer RNA maturation in Chlamydomonas mitochondria, chloroplast and the nucleus by a single RNase P protein.

Bonnard G, Gobert A, Arrivé M, Pinker F, Salinas-Giegé T, Giegé P.

Plant J. 2016 Aug;87(3):270-80. doi: 10.1111/tpj.13198. Epub 2016 Jul 6.


The Immune Battle against Helicobacter pylori Infection: NO Offense.

Gobert AP, Wilson KT.

Trends Microbiol. 2016 May;24(5):366-376. doi: 10.1016/j.tim.2016.02.005. Epub 2016 Feb 22. Review.


Distribution of Ribonucleoprotein and Protein-Only RNase P in Eukarya.

Lechner M, Rossmanith W, Hartmann RK, Thölken C, Gutmann B, Giegé P, Gobert A.

Mol Biol Evol. 2015 Dec;32(12):3186-93. doi: 10.1093/molbev/msv187. Epub 2015 Sep 3.


EGFR-independent mechanisms of acquired resistance to AZD9291 in EGFR T790M-positive NSCLC patients.

Planchard D, Loriot Y, André F, Gobert A, Auger N, Lacroix L, Soria JC.

Ann Oncol. 2015 Oct;26(10):2073-8. doi: 10.1093/annonc/mdv319. Epub 2015 Aug 12.


[HIV-related malignancies: state of art].

Gobert A, Mounier N, Lavole A, Poizot-Martin I, Spano JP.

Bull Cancer. 2014 Nov;101(11):1020-9. doi: 10.1684/bdc.2014.2032. Review. French.


Heme oxygenase-1 dysregulates macrophage polarization and the immune response to Helicobacter pylori.

Gobert AP, Verriere T, Asim M, Barry DP, Piazuelo MB, de Sablet T, Delgado AG, Bravo LE, Correa P, Peek RM Jr, Chaturvedi R, Wilson KT.

J Immunol. 2014 Sep 15;193(6):3013-22. doi: 10.4049/jimmunol.1401075. Epub 2014 Aug 8.


NsrR, GadE, and GadX interplay in repressing expression of the Escherichia coli O157:H7 LEE pathogenicity island in response to nitric oxide.

Branchu P, Matrat S, Vareille M, Garrivier A, Durand A, Crépin S, Harel J, Jubelin G, Gobert AP.

PLoS Pathog. 2014 Jan;10(1):e1003874. doi: 10.1371/journal.ppat.1003874. Epub 2014 Jan 9.


Helical repeats modular proteins are major players for organelle gene expression.

Hammani K, Bonnard G, Bouchoucha A, Gobert A, Pinker F, Salinas T, Giegé P.

Biochimie. 2014 May;100:141-50. doi: 10.1016/j.biochi.2013.08.031. Epub 2013 Sep 8. Review.


PPR proteins shed a new light on RNase P biology.

Pinker F, Bonnard G, Gobert A, Gutmann B, Hammani K, Sauter C, Gegenheimer PA, Giegé P.

RNA Biol. 2013;10(9):1457-68. doi: 10.4161/rna.25273. Epub 2013 Jun 19. Review.


Structural insights into protein-only RNase P complexed with tRNA.

Gobert A, Pinker F, Fuchsbauer O, Gutmann B, Boutin R, Roblin P, Sauter C, Giegé P.

Nat Commun. 2013;4:1353. doi: 10.1038/ncomms2358.


The c-di-GMP phosphodiesterase VmpA absent in Escherichia coli K12 strains affects motility and biofilm formation in the enterohemorrhagic O157:H7 serotype.

Branchu P, Hindré T, Fang X, Thomas R, Gomelsky M, Claret L, Harel J, Gobert AP, Martin C.

Vet Immunol Immunopathol. 2013 Mar 15;152(1-2):132-40. doi: 10.1016/j.vetimm.2012.09.029. Epub 2012 Sep 26.


PlantRNA, a database for tRNAs of photosynthetic eukaryotes.

Cognat V, Pawlak G, Duchêne AM, Daujat M, Gigant A, Salinas T, Michaud M, Gutmann B, Giegé P, Gobert A, Maréchal-Drouard L.

Nucleic Acids Res. 2013 Jan;41(Database issue):D273-9. doi: 10.1093/nar/gks935. Epub 2012 Oct 12.


Haem oxygenase-1 inhibits phosphorylation of the Helicobacter pylori oncoprotein CagA in gastric epithelial cells.

Gobert AP, Verriere T, de Sablet T, Peek RM Jr, Chaturvedi R, Wilson KT.

Cell Microbiol. 2013 Jan;15(1):145-56. doi: 10.1111/cmi.12039. Epub 2012 Nov 7.


PRORP proteins support RNase P activity in both organelles and the nucleus in Arabidopsis.

Gutmann B, Gobert A, Giegé P.

Genes Dev. 2012 May 15;26(10):1022-7. doi: 10.1101/gad.189514.112. Epub 2012 May 1.


Editorial: Orchestration of macrophage polarization by polyamines.

Gobert AP, Wilson KT.

J Leukoc Biol. 2012 May;91(5):677-9. doi: 10.1189/jlb.0112047. No abstract available.


Quantification of extracellular levels of corticosterone in the basolateral amygdaloid complex of freely-moving rats: a dialysis study of circadian variation and stress-induced modulation.

Bouchez G, Millan MJ, Rivet JM, Billiras R, Boulanger R, Gobert A.

Brain Res. 2012 May 3;1452:47-60. doi: 10.1016/j.brainres.2012.01.010. Epub 2012 Jan 16.


Cationic amino acid transporter 2 enhances innate immunity during Helicobacter pylori infection.

Barry DP, Asim M, Scull BP, Piazuelo MB, de Sablet T, Lewis ND, Coburn LA, Singh K, Ellies LG, Gobert AP, Chaturvedi R, Wilson KT.

PLoS One. 2011;6(12):e29046. doi: 10.1371/journal.pone.0029046. Epub 2011 Dec 14.


S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: II. A behavioral, neurochemical, and electrophysiological characterization.

Dekeyne A, Brocco M, Loiseau F, Gobert A, Rivet JM, Di Cara B, Cremers TI, Flik G, Fone KC, Watson DJ, Papp M, Sharp T, Serres F, Cespuglio R, Olivier B, Chan JS, Lavielle G, Millan MJ.

J Pharmacol Exp Ther. 2012 Mar;340(3):765-80. doi: 10.1124/jpet.111.187534. Epub 2011 Dec 16.


Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA).

Di Cara B, Maggio R, Aloisi G, Rivet JM, Lundius EG, Yoshitake T, Svenningsson P, Brocco M, Gobert A, De Groote L, Cistarelli L, Veiga S, De Montrion C, Rodriguez M, Galizzi JP, Lockhart BP, Cogé F, Boutin JA, Vayer P, Verdouw PM, Groenink L, Millan MJ.

J Neurosci. 2011 Nov 23;31(47):16928-40. doi: 10.1523/JNEUROSCI.2502-11.2011.


Disruption of nitric oxide signaling by Helicobacter pylori results in enhanced inflammation by inhibition of heme oxygenase-1.

Gobert AP, Asim M, Piazuelo MB, Verriere T, Scull BP, de Sablet T, Glumac A, Lewis ND, Correa P, Peek RM Jr, Chaturvedi R, Wilson KT.

J Immunol. 2011 Nov 15;187(10):5370-9. doi: 10.4049/jimmunol.1102111. Epub 2011 Oct 10.


Arginine and polyamines in Helicobacter pylori-induced immune dysregulation and gastric carcinogenesis.

Chaturvedi R, de Sablet T, Coburn LA, Gobert AP, Wilson KT.

Amino Acids. 2012 Feb;42(2-3):627-40. doi: 10.1007/s00726-011-1038-4. Epub 2011 Aug 28.

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