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Chronic exposure to cadmium is associated with a marked reduction in glomerular filtration rate.

Satarug S, Boonprasert K, Gobe GC, Ruenweerayut R, Johnson DW, Na-Bangchang K, Vesey DA.

Clin Kidney J. 2018 Nov 21;12(4):468-475. doi: 10.1093/ckj/sfy113. eCollection 2019 Aug.


Role of leptin as a biomarker for early detection of renal cell carcinoma? No evidence from a systematic review and meta-analysis.

Perumal K, Huin WK, Yap NY, Ong TA, Gobe GC, Rajandram R.

Med Hypotheses. 2019 Aug;129:109239. doi: 10.1016/j.mehy.2019.109239. Epub 2019 May 20. Erratum in: Med Hypotheses. 2019 Oct;131:109284.


Protease-activated receptor 2 does not contribute to renal inflammation or fibrosis in the obstructed kidney.

Ma FY, Han Y, Ozols E, Chew P, Vesey DA, Gobe GC, Morais C, Lohman RJ, Suen JY, Johnson DW, Fairlie DP, Nikolic-Paterson DJ.

Nephrology (Carlton). 2019 Sep;24(9):983-991. doi: 10.1111/nep.13635. Epub 2019 Jul 31.


Limitations to the Therapeutic Potential of Tyrosine Kinase Inhibitors and Alternative Therapies for Kidney Cancer.

Kamli H, Li L, Gobe GC.

Ochsner J. 2019 Summer;19(2):138-151. doi: 10.31486/toj.18.0015. Review.


Heavy metal imaging in fibrotic human kidney tissue using the synchrotron X-ray fluorescence microprobe.

Gobe GC, Mott SA, de Jonge M, Hoy WE.

Transl Androl Urol. 2019 May;8(Suppl 2):S184-S191. doi: 10.21037/tau.2019.03.15. Review.


Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease.

Owens EP, Vesey DA, Kassianos AJ, Healy H, Hoy WE, Gobe GC.

Transl Androl Urol. 2019 May;8(Suppl 2):S175-S183. doi: 10.21037/tau.2018.11.03. Review.


Patient-derived xenograft models to optimize kidney cancer therapies.

Patel A, Cohen S, Moret R, Maresh G, Gobe GC, Li L.

Transl Androl Urol. 2019 May;8(Suppl 2):S156-S165. doi: 10.21037/tau.2018.11.04. Review.


Prostate specific membrane antigen (PSMA) expression in vena cava tumour thrombi of clear cell renal cell carcinoma suggests a role for PSMA-driven tumour neoangiogenesis.

Morgantetti G, Ng KL, Samaratunga H, Rhee H, Gobe GC, Wood ST.

Transl Androl Urol. 2019 May;8(Suppl 2):S147-S155. doi: 10.21037/tau.2019.04.10.


Utility of cytokeratin 7, S100A1 and caveolin-1 as immunohistochemical biomarkers to differentiate chromophobe renal cell carcinoma from renal oncocytoma.

Ng KL, Ellis RJ, Samaratunga H, Morais C, Gobe GC, Wood ST.

Transl Androl Urol. 2019 May;8(Suppl 2):S123-S137. doi: 10.21037/tau.2018.11.02.


Translational research in kidney disease.

Gobe GC.

Transl Androl Urol. 2019 May;8(Suppl 2):S121-S122. doi: 10.21037/tau.2019.05.11. No abstract available.


Tumor size and postoperative kidney function following radical nephrectomy.

Ellis RJ, White VM, Bolton DM, Coory MD, Davis ID, Francis RS, Giles GG, Gobe GC, Neale RE, Wood ST, Jordan SJ.

Clin Epidemiol. 2019 May 6;11:333-348. doi: 10.2147/CLEP.S197968. eCollection 2019.


Establishment of epithelial and fibroblast cell cultures and cell lines from primary renal cancer nephrectomies.

Yap NY, Ong TA, Morais C, Pailoor J, Gobe GC, Rajandram R.

Cell Biol Int. 2019 Jun;43(6):715-725. doi: 10.1002/cbin.11150. Epub 2019 May 6.


Incident Chronic Kidney Disease After Radical Nephrectomy for Renal Cell Carcinoma.

Ellis RJ, White VM, Bolton DM, Coory MD, Davis ID, Francis RS, Giles GG, Gobe GC, Marco DJT, Neale RE, Wood ST, Jordan SJ; IMPROVE Investigators.

Clin Genitourin Cancer. 2019 Jun;17(3):e581-e591. doi: 10.1016/j.clgc.2019.02.011. Epub 2019 Mar 15.


The inverse association of glomerular function and urinary β2-MG excretion and its implications for cadmium health risk assessment.

Satarug S, Vesey DA, Nishijo M, Ruangyuttikarn W, Gobe GC.

Environ Res. 2019 Jun;173:40-47. doi: 10.1016/j.envres.2019.03.026. Epub 2019 Mar 14.


Pharmacological inhibition of protease-activated receptor-2 reduces crescent formation in rat nephrotoxic serum nephritis.

Han Y, Tian L, Ma F, Tesch G, Vesey DA, Gobe GC, Lohman RJ, Morais C, Suen JY, Fairlie DP, Nikolic-Paterson DJ.

Clin Exp Pharmacol Physiol. 2019 May;46(5):456-464. doi: 10.1111/1440-1681.13077. Epub 2019 Mar 25.


GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma.

Shen K, Vesey DA, Ellis RJ, Del Vecchio SJ, Cho Y, Teixeira-Pinto A, McGuckin MA, Johnson DW, Gobe GC.

PLoS One. 2019 Jan 17;14(1):e0210246. doi: 10.1371/journal.pone.0210246. eCollection 2019.


Chronic kidney cortical damage is associated with baseline kidney function and albuminuria in patients managed with radical nephrectomy for kidney tumours.

Ellis RJ, Kalma B, Del Vecchio SJ, Aliano DN, Ng KL, Dimeski G, Ma L, Guard D, Bertram JF, Morais C, Oliver K, Wood ST, Gobe GC, Francis RS.

Pathology. 2019 Jan;51(1):32-38. doi: 10.1016/j.pathol.2018.10.009. Epub 2018 Nov 23.


Is renal tubular cadmium toxicity clinically relevant?

Boonprasert K, Vesey DA, Gobe GC, Ruenweerayut R, Johnson DW, Na-Bangchang K, Satarug S.

Clin Kidney J. 2018 Oct;11(5):681-687. doi: 10.1093/ckj/sfx153. Epub 2018 Feb 2.


End-Stage Kidney Disease following Surgical Management of Kidney Cancer.

Ellis RJ, Edey DP, Del Vecchio SJ, McStea M, Campbell SB, Hawley CM, Johnson DW, Morais C, Jordan SJ, Francis RS, Wood ST, Gobe GC; Cancer Alliance Queensland.

Clin J Am Soc Nephrol. 2018 Nov 7;13(11):1641-1648. doi: 10.2215/CJN.06560518. Epub 2018 Sep 28.


Leptin and its receptor: can they help to differentiate chromophobe renal cell carcinoma from renal oncocytoma?

Ng KL, Del Vecchio SJ, Samaratunga H, Morais C, Rajandram R, Vesey DA, Wood ST, Gobe GC.

Pathology. 2018 Aug;50(5):504-510. doi: 10.1016/j.pathol.2018.01.007. Epub 2018 Jun 30.


Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells.

Song W, Thakor P, Vesey DA, Gobe GC, Morais C.

Biomed Pharmacother. 2018 Oct;106:247-254. doi: 10.1016/j.biopha.2018.06.126. Epub 2018 Jun 28.


Nuclear factor-kappa B subunits and their prognostic cancer-specific survival value in renal cell carcinoma patients.

Ng KL, Yap NY, Rajandram R, Small D, Pailoor J, Ong TA, Razack AH, Wood ST, Morais C, Gobe GC.

Pathology. 2018 Aug;50(5):511-518. doi: 10.1016/j.pathol.2018.03.003. Epub 2018 Jun 21.


Association between preoperative hydration status and acute kidney injury in patients managed surgically for kidney tumours.

Ellis RJ, Del Vecchio SJ, Kalma B, Ng KL, Morais C, Francis RS, Gobe GC, Ferris R, Wood ST.

Int Urol Nephrol. 2018 Jul;50(7):1211-1217. doi: 10.1007/s11255-018-1901-2. Epub 2018 Jun 5.


Predictors of new-onset chronic kidney disease in patients managed surgically for T1a renal cell carcinoma: An Australian population-based analysis.

Ahn T, Ellis RJ, White VM, Bolton DM, Coory MD, Davis ID, Francis RS, Giles GG, Gobe GC, Hawley CM, Johnson DW, Marco DJT, McStea M, Neale RE, Pascoe EM, Wood ST, Jordan SJ; IMPROVE investigators.

J Surg Oncol. 2018 Jun;117(7):1597-1610. doi: 10.1002/jso.25037. Epub 2018 May 22.


Outcome Measures Used to Report Kidney Function in Studies Investigating Surgical Management of Kidney Tumours: A Systematic Review.

Ellis RJ, Cho Y, Del Vecchio SJ, McStea M, Morais C, Coombes JS, Wood ST, Gobe GC, Francis RS.

Eur Urol Focus. 2018 May 1. pii: S2405-4569(18)30102-0. doi: 10.1016/j.euf.2018.04.012. [Epub ahead of print] Review.


Indoxyl Sulfate Induces Apoptosis and Hypertrophy in Human Kidney Proximal Tubular Cells.

Ellis RJ, Small DM, Ng KL, Vesey DA, Vitetta L, Francis RS, Gobe GC, Morais C.

Toxicol Pathol. 2018 Jun;46(4):449-459. doi: 10.1177/0192623318768171. Epub 2018 Apr 22.


N-acetyl-cysteine increases cellular dysfunction in progressive chronic kidney damage after acute kidney injury by dampening endogenous antioxidant responses.

Small DM, Sanchez WY, Roy SF, Morais C, Brooks HL, Coombes JS, Johnson DW, Gobe GC.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F956-F968. doi: 10.1152/ajprenal.00057.2017. Epub 2018 Jan 10.


The Correlates of Kidney Dysfunction – Tumour Nephrectomy Database (CKD-TUNED) Study: Protocol for a Prospective Observational Study

Ellis RJ, Del Vecchio SJ, Ng KL, Owens EP, Coombes JS, Morais C, Francis RS, Wood ST, Gobe GC.

Asian Pac J Cancer Prev. 2017 Dec 29;18(12):3281-3285.


Factors associated with acutely elevated serum creatinine following radical tumour nephrectomy: the Correlates of Kidney Dysfunction-Tumour Nephrectomy Database study.

Ellis RJ, Del Vecchio SJ, Ng KL, Dimeski G, Pascoe EM, Hawley CM, Johnson DW, Vesey DA, Coombes JS, Morais C, Francis RS, Wood ST, Gobe GC.

Transl Androl Urol. 2017 Oct;6(5):899-909. doi: 10.21037/tau.2017.08.15.


Adenine-induced chronic kidney disease in rats.

Diwan V, Brown L, Gobe GC.

Nephrology (Carlton). 2018 Jan;23(1):5-11. doi: 10.1111/nep.13180. Review.


Translational Significance for Tumor Metastasis of Tumor-Associated Macrophages and Epithelial-Mesenchymal Transition.

Song W, Mazzieri R, Yang T, Gobe GC.

Front Immunol. 2017 Sep 13;8:1106. doi: 10.3389/fimmu.2017.01106. eCollection 2017. Review.


Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies.

Shen K, Johnson DW, Vesey DA, McGuckin MA, Gobe GC.

Cell Stress Chaperones. 2018 May;23(3):317-334. doi: 10.1007/s12192-017-0844-3. Epub 2017 Sep 27. Review.


Anti-Coagulant and Anti-Thrombotic Properties of Blacklip Abalone (Haliotis rubra): In Vitro and Animal Studies.

Suleria HAR, Masci PP, Zhao KN, Addepalli R, Chen W, Osborne SA, Gobe GC.

Mar Drugs. 2017 Aug 4;15(8). pii: E240. doi: 10.3390/md15080240.


Optimising assessment of kidney function when managing localised renal masses.

Ellis RJ, Joshi A, Ng KL, Francis RS, Gobe GC, Wood ST.

Med J Aust. 2017 Aug 7;207(3):127-133. Review.


Current health risk assessment practice for dietary cadmium: Data from different countries.

Satarug S, Vesey DA, Gobe GC.

Food Chem Toxicol. 2017 Aug;106(Pt A):430-445. doi: 10.1016/j.fct.2017.06.013. Epub 2017 Jun 8. Review.


In vitro anti-thrombotic and anti-coagulant properties of blacklip abalone (Haliotis rubra) viscera hydrolysate.

Suleria HAR, Masci PP, Addepalli R, Chen W, Gobe GC, Osborne SA.

Anal Bioanal Chem. 2017 Jul;409(17):4195-4205. doi: 10.1007/s00216-017-0367-x. Epub 2017 May 11.


Maslinic Acid Inhibits Proliferation of Renal Cell Carcinoma Cell Lines and Suppresses Angiogenesis of Endothelial Cells.

Thakor P, Song W, Subramanian RB, Thakkar VR, Vesey DA, Gobe GC.

J Kidney Cancer VHL. 2017 Mar 21;4(1):16-24. doi: 10.15586/jkcvhl.2017.64. eCollection 2017.


Health Risk Assessment of Dietary Cadmium Intake: Do Current Guidelines Indicate How Much is Safe?

Satarug S, Vesey DA, Gobe GC.

Environ Health Perspect. 2017 Mar;125(3):284-288. doi: 10.1289/EHP108. Epub 2017 Mar 1.


MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance.

Sheng Y, Ng CP, Lourie R, Shah ET, He Y, Wong KY, Seim I, Oancea I, Morais C, Jeffery PL, Hooper J, Gobe GC, McGuckin MA.

Int J Cancer. 2017 May 15;140(10):2351-2363. doi: 10.1002/ijc.30651. Epub 2017 Feb 28.


Kidney Cadmium Toxicity, Diabetes and High Blood Pressure: The Perfect Storm.

Satarug S, Vesey DA, Gobe GC.

Tohoku J Exp Med. 2017 Jan;241(1):65-87. doi: 10.1620/tjem.241.65. Review.


Effects of exercise and lifestyle intervention on oxidative stress in chronic kidney disease.

Small DM, Beetham KS, Howden EJ, Briskey DR, Johnson DW, Isbel NM, Gobe GC, Coombes JS.

Redox Rep. 2017 May;22(3):127-136. doi: 10.1080/13510002.2016.1276314. Epub 2017 Jan 11.


Granzyme M has a critical role in providing innate immune protection in ulcerative colitis.

Souza-Fonseca-Guimaraes F, Krasnova Y, Putoczki T, Miles K, MacDonald KP, Town L, Shi W, Gobe GC, McDade L, Mielke LA, Tye H, Masters SL, Belz GT, Huntington ND, Radford-Smith G, Smyth MJ.

Cell Death Dis. 2016 Jul 21;7:e2302. doi: 10.1038/cddis.2016.215.


The role of cGMP and its signaling pathways in kidney disease.

Shen K, Johnson DW, Gobe GC.

Am J Physiol Renal Physiol. 2016 Oct 1;311(4):F671-F681. doi: 10.1152/ajprenal.00042.2016. Epub 2016 Jul 13. Review.


The stress response of human proximal tubule cells to cadmium involves up-regulation of haemoxygenase 1 and metallothionein but not cytochrome P450 enzymes.

Boonprasert K, Satarug S, Morais C, Gobe GC, Johnson DW, Na-Bangchang K, Vesey DA.

Toxicol Lett. 2016 May 13;249:5-14. doi: 10.1016/j.toxlet.2016.02.016. Epub 2016 Mar 19.


Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways.

Gobe GC, Ng KL, Small DM, Vesey DA, Johnson DW, Samaratunga H, Oliver K, Wood S, Barclay JL, Rajandram R, Li L, Morais C.

Biochem Biophys Res Commun. 2016 Apr 22;473(1):47-53. doi: 10.1016/j.bbrc.2016.03.048. Epub 2016 Mar 17.


Carvedilol protects the kidneys of tumor-bearing mice without impairing the biodistribution or the genotoxicity of cisplatin.

Carvalho Rodrigues MA, dos Santos NA, da Silva Faria MC, Rodrigues JL, Kinoshita A, Baffa O, Antunes LM, Barbosa F Jr, Gobe GC, dos Santos AC.

Chem Biol Interact. 2016 Feb 5;245:59-65. doi: 10.1016/j.cbi.2015.12.020. Epub 2016 Jan 2.


Protection against oxidative stress-induced apoptosis in kidney epithelium by Angelica and Astragalus.

Shahzad M, Small DM, Morais C, Wojcikowski K, Shabbir A, Gobe GC.

J Ethnopharmacol. 2016 Feb 17;179:412-9. doi: 10.1016/j.jep.2015.12.027. Epub 2015 Dec 21.


Multifocal Primary Neoplasms in Kidney Allografts: Evaluation of Two Cases.

Ellis RJ, Ng KL, Samaratunga H, Del Vecchio SJ, Wood ST, Gobe GC.

J Kidney Cancer VHL. 2016 Jun 13;3(2):14-22. doi: 10.15586/jkcvhl.2016.53. eCollection 2016.


Decreased Expression of Inhibitor of Caspase-Activated DNase (ICAD) in Renal Cell Carcinoma - Tissue Microarray of Human Samples.

Rajandram R, Razack AH, Ng KL, Gobe GC.

J Kidney Cancer VHL. 2016 Mar 22;3(1):1-11. doi: 10.15586/jkcvhl.2016.47. eCollection 2016.

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